{"title":"AIDS, HIV, antiretrovirals and Africa.","authors":"Brian Gazzard","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":81665,"journal":{"name":"Journal of HIV therapy","volume":"11 1","pages":"4-6"},"PeriodicalIF":0.0,"publicationDate":"2006-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26028223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"13th Conference on Retroviruses and Opportunistic Infections (CROI), Denver, USA, 5-8 February 2005.","authors":"Stefano Rusconi","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":81665,"journal":{"name":"Journal of HIV therapy","volume":"11 1","pages":"20-2"},"PeriodicalIF":0.0,"publicationDate":"2006-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26028227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The current status of antiretroviral therapy in Africa.","authors":"Dorothy H Bray","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":81665,"journal":{"name":"Journal of HIV therapy","volume":"11 1","pages":"7-10"},"PeriodicalIF":0.0,"publicationDate":"2006-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26028224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laurence John, Andrew Kambugu, Patricia Mwebaze Songa, Barbara Castelnuovo, Robert Colebunders, Moses Kamya
{"title":"Are the best antiretrovirals being used in Africa?","authors":"Laurence John, Andrew Kambugu, Patricia Mwebaze Songa, Barbara Castelnuovo, Robert Colebunders, Moses Kamya","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":81665,"journal":{"name":"Journal of HIV therapy","volume":"11 1","pages":"11-5"},"PeriodicalIF":0.0,"publicationDate":"2006-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26028225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Protease inhibitors: the current status.","authors":"Brenda Dauer","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":81665,"journal":{"name":"Journal of HIV therapy","volume":"10 4","pages":"72-4"},"PeriodicalIF":0.0,"publicationDate":"2005-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25889553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pilar García-Gasco, Francisco Blanco, Vincent Soriano
{"title":"Integrase inhibitors.","authors":"Pilar García-Gasco, Francisco Blanco, Vincent Soriano","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":81665,"journal":{"name":"Journal of HIV therapy","volume":"10 4","pages":"75-8"},"PeriodicalIF":0.0,"publicationDate":"2005-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25889554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Meeting report of the 10th European AIDS Conference (EACS) 17-20 November 2005.","authors":"Nicholas Chew, John S Lambert","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":81665,"journal":{"name":"Journal of HIV therapy","volume":"10 4","pages":"79-80"},"PeriodicalIF":0.0,"publicationDate":"2005-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25889555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"New drugs for HIV therapy.","authors":"Jürgen K Rockstroh","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":81665,"journal":{"name":"Journal of HIV therapy","volume":"10 4","pages":"66-7"},"PeriodicalIF":0.0,"publicationDate":"2005-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25889549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"CCR5 antagonists: a new tool in fighting HIV.","authors":"Boris Jülg, Frank-Detlef Goebel","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Chemokine receptors are essential for cell entry by HIV. The two chemokine receptors most relevant to this process are CC chemokine receptor 5 (CCR5) and CXC chemokine receptor 4 (CXCR4) since a delayed onset of disease can be achieved by inhibition of either receptor. Therefore, chemokine receptor antagonists, in particular inhibitors of CCR5, represent a promising new class of anti-HIV agents. In this review, we summarise current drug candidates, give an insight into how they interact with CCR5, and discuss requirements and restrictions for these compounds.</p>","PeriodicalId":81665,"journal":{"name":"Journal of HIV therapy","volume":"10 4","pages":"68-71"},"PeriodicalIF":0.0,"publicationDate":"2005-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25889552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"CD40 activation: lessons for HIV immunotherapy from malignancies?","authors":"Rifca Le Dieu, John Gribben","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In HIV, the immune defects seen are due not only to a decrease in T-cell numbers, but also to qualitative impairment in T-cell function as well as decreased antigen-presenting cell (APC) function. These defects in cell-mediated immunity lead to increased level of infection, contributing to inability to clear the HIV virus, and an increased incidence of tumours. One of the major defects in HIV appears to be the failure of CD4 T cells to provide CD 154 (CD40 ligand)-mediated help, which is required for APC function. In lymphomas, activation through CD40 leads to increased APC activity and induction of immune responses against tumours. Such an effect may also be useful in HIV to increase response against the virus and improve immune surveillance of tumours.</p>","PeriodicalId":81665,"journal":{"name":"Journal of HIV therapy","volume":"10 3","pages":"51-5"},"PeriodicalIF":0.0,"publicationDate":"2005-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25778039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}