Archives of Disease in Childhood最新文献

{"title":"Rethinking temporary absence from school in Chinese adolescents.","authors":"Fen Cheng, Yulan Yu, Manjun Shen","doi":"10.1136/archdischild-2025-329887","DOIUrl":"10.1136/archdischild-2025-329887","url":null,"abstract":"","PeriodicalId":8150,"journal":{"name":"Archives of Disease in Childhood","volume":" ","pages":"919-920"},"PeriodicalIF":3.4,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146099687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Developmental outcomes in 4-year-old children born in the first COVID-19 lockdown in England: preliminary findings from the Born In COVID Year - Core Lockdown Effects (BICYCLE) study.","authors":"Nicola Botting, Chelo Del Rosario, Jane Flynn, Stian Reimers, Catherine Davies, Nayeli Gonzalez-Gomez, Alexandra Hendry, Elisabeth Hill, Michelle McGillion, Becky Moss, Laura Shapiro, Lucy A Henry","doi":"10.1136/archdischild-2025-329529","DOIUrl":"10.1136/archdischild-2025-329529","url":null,"abstract":"<p><strong>Background/objective: </strong>Children born during England's COVID-19 lockdowns experienced markedly limited social exposure during a crucial developmental window. Given the importance of early interactions in shaping language, executive function and motor skills, this observational cross-sectional study examined developmental outcomes at age 4.</p><p><strong>Methods: </strong>205 children born in lockdown were assessed using standardised measures with published prepandemic norms: expressive vocabulary, expressive language and receptive language (Expressive Vocabulary, Word Structure and Sentence Structure subtests of the Clinical Evaluation of Language Fundamentals Preschool-second UK edition); receptive vocabulary (British Picture Vocabulary Scale, third edition); executive function (Global Executive Composite (GEC) and Emergent Metacognition Index (EMI) subscales of the Behaviour Rating Inventory of Executive Function-Preschool); motor skills (Motor Skills subscale from the Vineland Adaptive Behaviour Scales) and non-verbal reasoning (Matrices subtest from the British Ability Scales-3). Analyses (n=189-205) compared scores against prepandemic normative expectations and a within-sample benchmark of non-verbal reasoning to assess strengths and weaknesses against general cognitive development.</p><p><strong>Results: </strong>Compared with normative expectations, Sentence Structure (d=0.59), Expressive Vocabulary (d=0.24), receptive vocabulary (d=0.47) and Matrices (d=0.42) were significantly higher than expected for age. Caregiver-reported executive function was notably lower (GEC, d=-0.46; EMI, d=-0.36), while Word Structure (d=0.01) and Motor Skills (d=0.09) showed no differences. Benchmarked against non-verbal reasoning, Word Structure (d=-0.35), Expressive Vocabulary (d=-0.22), executive function (GEC, d=-0.72; EMI, d=-0.63) and Motor Skills (d=-0.33) were lower than cognitive potential. Sentence Structure (d=0.08) and receptive vocabulary (d=-0.01) were consistent with non-verbal reasoning.</p><p><strong>Conclusions: </strong>Caregiver-reported executive function was the most noteworthy area of concern for children born in lockdown. Expressive language and motor skills were lower than a benchmark of non-verbal reasoning, suggesting some impacts in relation to cognitive potential. This may lead to educational vulnerabilities and additional support needs in classrooms. Overall, these findings offer valuable early insight into postpandemic developmental impacts and underscore the urgent need for responsive educational policy and targeted support for those now in schooling.</p>","PeriodicalId":8150,"journal":{"name":"Archives of Disease in Childhood","volume":" ","pages":"910-918"},"PeriodicalIF":3.4,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13638306/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148444193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A century or more of cardiac morphology in the United Kingdom.","authors":"Robert H Anderson","doi":"10.1136/archdischild-2025-329878","DOIUrl":"10.1136/archdischild-2025-329878","url":null,"abstract":"","PeriodicalId":8150,"journal":{"name":"Archives of Disease in Childhood","volume":" ","pages":"840-842"},"PeriodicalIF":3.4,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145676175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnosis in children with Marfan syndrome: red flags for early identification.","authors":"Leonie Tyvaert, Simon D'hulst, Katya De Groote, Bert Callewaert, Hans De Wilde, Joseph Panzer, Kristof Vandekerckhove, Laura Muiño-Mosquera","doi":"10.1136/archdischild-2026-330318","DOIUrl":"10.1136/archdischild-2026-330318","url":null,"abstract":"<p><strong>Background: </strong>Marfan syndrome (MFS) is a multisystemic disorder caused by pathogenic (P) variants in the <i>fibrillin-1</i> gene (<i>FBN1</i>), associated with life-threatening cardiovascular complications. Early diagnosis enables preventive interventions, yet recognition in children can be challenging.</p><p><strong>Objective: </strong>To identify common diagnostic traits in children with MFS that may assist general paediatricians in the recognition of children with MFS and lead to early detection of the disease.</p><p><strong>Study design: </strong>This retrospective study included 129 children who underwent genetic testing due to a suspicion of MFS. Personal and family history, clinical features and echocardiographic results were compared between those children where a (likely)P ((L)P) variant in <i>FBN1</i> was found (n=64) and those with normal genetic testing (n=65).</p><p><strong>Results: </strong>Children carrying a (L)P variant in <i>FBN1</i> were significantly younger (7.6±4.2 years vs 11.2±4.5 years, p<0.001) and more often met the revised Ghent criteria based on clinical features (60.9% vs 1.5%, p<0.001). Six key predictors of MFS were identified: percentile height (OR 1.1 (CI 1.0 to 1.1), p<0.001), aortic root z-score ≥2 (OR 2.1 (CI 1.3 to 3.4), p=0.002), positive family history of aortic aneurysms/dissections (positive family history) (OR 8.0 (CI 1.7 to 37.0), p=0.008), increased arm-span (OR 21.0 (CI 1.0 to 443.1), p=0.050), hindfoot deformity (OR 145.7 (CI 7.7 to 2766.6), p<0.001) and ectopia lentis (EL)(41% vs 0%, p<0.001).</p><p><strong>Conclusions: </strong>In children with clinically suspected MFS, a positive family history, increased aortic root z-score, EL, tall stature, increased arm-span and hindfoot deformity were significant predictors of a molecularly confirmed diagnosis of MFS.</p>","PeriodicalId":8150,"journal":{"name":"Archives of Disease in Childhood","volume":" ","pages":"879-884"},"PeriodicalIF":3.4,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147589569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Children of the sulphur mines: the tragedy of the <i>Carusi</i> in 19th-century Sicily.","authors":"Matteo Bazzano, Michele Augusto Riva","doi":"10.1136/archdischild-2025-329910","DOIUrl":"10.1136/archdischild-2025-329910","url":null,"abstract":"","PeriodicalId":8150,"journal":{"name":"Archives of Disease in Childhood","volume":" ","pages":"921-923"},"PeriodicalIF":3.4,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146091815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abdominal POCUS in the paediatric emergency department: how does UK use relate to that overseas? A snapshot PERUKI survey.","authors":"David McCreary, Nigel Chan, Jon Rees, Niall Mullen, Owen Hibberd, Peter James Snelling","doi":"10.1136/archdischild-2025-329932","DOIUrl":"10.1136/archdischild-2025-329932","url":null,"abstract":"","PeriodicalId":8150,"journal":{"name":"Archives of Disease in Childhood","volume":" ","pages":"924-925"},"PeriodicalIF":3.4,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148306650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Real-world outcomes of hybrid closed-loop insulin pump therapy in UK children and young people with type 1 diabetes and high HbA1c: a multicentre retrospective cohort study.","authors":"Anna Caitlin King, Peter Christian, Paul Bassett, Edward Holloway","doi":"10.1136/archdischild-2026-330408","DOIUrl":"10.1136/archdischild-2026-330408","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate changes in glycated haemoglobin (HbA1c) following initiation of hybrid closed-loop (HCL) insulin pump therapy in children and young people (CYP) with previously elevated HbA1c in a real-world multicentre setting.</p><p><strong>Design: </strong>Retrospective multicentre observational cohort study.</p><p><strong>Setting: </strong>13 National Health Service paediatric diabetes units within a regional diabetes network in England, UK.</p><p><strong>Patients: </strong>CYP aged ≤19 years with type 1 diabetes of more than 1 year's duration and HbA1c ≥69 mmol/mol at the time of HCL initiation and at least 3 months prior.</p><p><strong>Interventions: </strong>Initiation of HCL insulin pump therapy.</p><p><strong>Main outcome measures: </strong>Primary outcome was change in HbA1c following HCL initiation. Secondary outcomes included subgroup and pump system comparisons and changes in diabetes-related hospital admissions.</p><p><strong>Results: </strong>A total of 220 participants were included. HbA1c decreased significantly following HCL initiation (p<0.001), falling from a mean of 82.5 mmol/mol at baseline to 72.8 mmol/mol within the first 3 months and remaining stable thereafter with a mean value of 69.3 mmol/mol at 12 months. Improvements were observed across all subgroups, with the greatest reductions in those with very high baseline HbA1c (>100 mmol/mol) and in participants transitioning from multiple daily injections. Outcomes were similar across HCL pump systems, and diabetes-related hospital admissions decreased overall following HCL initiation.</p><p><strong>Conclusions: </strong>In this large, real-world cohort of CYP with high HbA1c, initiation of HCL therapy was associated with sustained improvements in glycaemic control and fewer diabetes-related hospital admissions, supporting its use in this high-risk population.</p>","PeriodicalId":8150,"journal":{"name":"Archives of Disease in Childhood","volume":" ","pages":"891-896"},"PeriodicalIF":3.4,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148270028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal melanonychia in a child.","authors":"Ayona Dey, Katy Tuthill, David Tuthill","doi":"10.1136/archdischild-2026-331274","DOIUrl":"https://doi.org/10.1136/archdischild-2026-331274","url":null,"abstract":"","PeriodicalId":8150,"journal":{"name":"Archives of Disease in Childhood","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149001145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"BronchStartStop study: a maternal bivalent RSV prefusion F vaccine.","authors":"","doi":"10.1136/archdischild-2026-331530","DOIUrl":"https://doi.org/10.1136/archdischild-2026-331530","url":null,"abstract":"","PeriodicalId":8150,"journal":{"name":"Archives of Disease in Childhood","volume":"111 10","pages":"855"},"PeriodicalIF":3.4,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149001206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of physical symptoms persisting in children a year after the Türkiye earthquake.","authors":"Sümeyye Özarslan, Yeliz Suna Dağ, Emriye Hilal Yayan, Mürşide Zengin, Mehmet Emin Düken, Feyza İnceoğlu","doi":"10.1136/archdischild-2026-331178","DOIUrl":"https://doi.org/10.1136/archdischild-2026-331178","url":null,"abstract":"<p><strong>Objective: </strong>While the impact of earthquakes on children's mental health is frequently discussed in the literature, the extent of physical health problems remains unclear. This study was conducted to identify the short-term and long-term physical health problems experienced by children exposed to earthquakes.</p><p><strong>Design: </strong>A descriptive and retrospective design was used.</p><p><strong>Methods: </strong>The study included a total of 1073 children aged 6-16 living in temporary shelters (tents and containers). Data were collected 1 year after the earthquakes. The children's physical health was assessed using a Physical Examination and Care Form specifically developed for this study. Data were collected through self-reports from children and parents as well as observations and assessments by researchers.</p><p><strong>Results: </strong>Following the earthquake, children experienced respiratory problems (20.3%), respiratory tract infections (10.6%) and sputum production (24.8%). Digestive problems included nausea and vomiting (16.5%), loss of appetite (15.3%) and diarrhoea (10.2%). In terms of sleep, 29.3% of children had difficulty falling asleep, 24.9% experienced shorter sleep durations, 18.3% woke up frequently and 11.4% had nightmares. Furthermore, urinary incontinence was reported in 8.7% of cases, faecal incontinence in 4.4%, musculoskeletal pain in 13.4%, limited mobility in 7.5%, joint problems in 6.2% and coordination disorders in 4.8%.</p><p><strong>Conclusion: </strong>Many of the children who lived through the Türkiye earthquake experienced physical health problems both immediately after earthquakes and 1 year later. A holistic assessment and long-term monitoring of the health impacts of such disasters on children are crucial for identifying their physical care needs and mitigating these health issues.</p>","PeriodicalId":8150,"journal":{"name":"Archives of Disease in Childhood","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148975520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}