Archives of Clinical Microbiology最新文献

{"title":"The Corona Virus Problem Via Linear Time-Equation","authors":"E. Gluskin","doi":"10.36648/1989-8436.21.12.151","DOIUrl":"https://doi.org/10.36648/1989-8436.21.12.151","url":null,"abstract":"Besides the visual heuristic side, our research of the Corona Virus Problem includes the line of physics considerations and the equational line. The present work is merely devoted to the latter line. It appears that some proposed special covering of some of the Corona Virus molecules, which is purposed to cause an antagonism between these molecules and those uncovered, leads to turning a nonlinear balance equation into a linear time-variant one (which the physicists sometime call \"parametric equation\").","PeriodicalId":8142,"journal":{"name":"Archives of Clinical Microbiology","volume":"19 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72566189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sero Prevalence and Risk factors forSheep Pox and Lumpy Skin Disease and Their Comparison to Capri Pox Double Antigen Multispecies ELISA in Khartoum and Kordofan States in Sudan","authors":"Mohammed E. Mansour, Maximillian Baumann, GelagayAyelet","doi":"10.36648/1989-8436.21.S3.001","DOIUrl":"https://doi.org/10.36648/1989-8436.21.S3.001","url":null,"abstract":"A cross-sectional survey was performed in the Kordofan region, from March to September 2011 was compared to Capripox Double Ag ELISA for multispecies. The estimated overall sero-prevalence of sheep pox in Kordofan region was 73.4% determined by virus neutralization and was prevalent in both South and North Kordofan states at 85% and 63.6% respectively. However, Seroprevalence for lumpy skin A cross-sectional survey was performed in the Kordofan region, from March to September 2011 was compared to Capripox Double Ag ELISA for multispecies. The estimated overall sero-Prevalence of sheep pox in Kordofan region was 73.4% determined by virus neutralization and was prevalent in both South and North Kordofan states at 85% and 63.6% respectively. However, Sero-Prevalence for lumpy skin disease was 5% and 62% for sheep pox by using Capripox Double Ag ELISA. The serological information was used to identify potential risk factors associated with sheep pox outbreaks. The risk factors identified were the breed, age, sex, species, movement patterns, herd size and geographic region. In addition, a questionnaire explored producer’s knowledge about the disease in the Sudan. The results of the questionnaire were that both nomadic as well as fixed farmers were generally aware of sheep pox as a disease, but most did not have full knowledge about the disease. Greater than half of producers experienced the disease in the past 2 years and did not have their sheep vaccinated.disease was 5% and 62% for sheep pox by using Capripox Double Ag ELISA. The serological information was used to identify potential risk factors associated with sheep pox outbreaks. The risk factors identified were the breed, age, sex, species, movement patterns, herd size and geographic region. In addition, a questionnaire explored producer’s knowledge about the disease in the Sudan. The results of the questionnaire were that both nomadic as well as fixed farmers were generally aware of sheep pox as a disease, but most did not have full knowledge about the disease. Greater than half of producers experienced the disease in the past 2 years and did not have their sheep vaccinated.","PeriodicalId":8142,"journal":{"name":"Archives of Clinical Microbiology","volume":"80 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80908796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Forming a Non-Profit Organization for Patients with a Urological Disease in 1984: Does it relate to Clinical Microbiology Today?","authors":"V. Ratner","doi":"10.36648/1989-8436.21.12.138","DOIUrl":"https://doi.org/10.36648/1989-8436.21.12.138","url":null,"abstract":"Interstitial Cystitis (IC), also known as Painful Bladder Syndrome (PBS), was initially described in the mid 1800’s. It was not until 1984 that a patient non-profit organization, the Interstitial Cystitis Association (ICA), was formed in order to work with IC patients and the National Institutes of Health (NIH) to define and increase research on this enigmatic and debilitating condition. The media played an important role in bringing together patients and helping them understand that they were not alone in their suffering. Epidemiological studies legitimized the disease and research at the NIH and other academic institutions progressed enormously. However, despite over 30 years of hard work, urologists have been unable to determine a cause for IC or any truly effective treatments to help patients suffering from this condition. Collaboration with other specialties, in particular clinical microbiology, may prove fruitful in advancing research into the cause and potential treatments for IC.","PeriodicalId":8142,"journal":{"name":"Archives of Clinical Microbiology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88927202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of Retreatment with ombitasvir/paritaprevir/ ritonavir, dasabuvir+sofosbuvir+ribavirin in Patients with Chronic Hepatitis C, Subtype 1b and Cirrhosis, Who Failed Previous with First- and Second-generation NS5A Inhibitors","authors":"S. V. Fedorchenko, Tatiana Martynovych, Zhanna Klimenko, Iryna Soliank","doi":"10.36648/1989-8436.21.S4.167","DOIUrl":"https://doi.org/10.36648/1989-8436.21.S4.167","url":null,"abstract":"The use of Directâ?Acting Antiviral agents (DAAs) in patients with chronic HCV GenoType (GT) 1 infection results in Sustained Virologic Response (SVR) rates of 95%-97%, but 3%-5% of patients experience virologic failure. We observed 41 patients infected with HCV subtype 1b who failed previous treatment with DAAs, including 37 subjects (90.2%) with liver cirrhosis. In total, 30(73.2%) subjects previously received NS5A inhibitors of the first generation (ledipasvir, daclatasvir, or ombitasvir) and 11 subjects (26.8%) received NS5A inhibitors of the second generation (velpatasvir). All patients received retreatment with a combination of ombitasvir/paritaprevir/ritonavir and dasabuvir (3D) with Sofosbuvir (SOF) and Ribavirin (RBV). We compared SVR12 rates depending on fibrosis stage, presence of just single or double NS5A mutation (L31M/V/I and/or Y93H), and the generation of previously used NS5A inhibitors. Observed SVR12 rates were as follows: 97.6% (40/41 patients) overall; 100% in patients without cirrhosis (n=4) versus 97.3% in those with cirrhosis (n=37); 100% with single L31M/V/I or Y93H mutation (n=22) versus 94.4% with double mutations (n=18); 100% in patients who failed previous treatment with firstâ?generation (n=30) versus 90.9% in those who failed previous treatment with secondâ?generation NS5A inhibitors (n=11).","PeriodicalId":8142,"journal":{"name":"Archives of Clinical Microbiology","volume":"134 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88746110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Brief Overview on the COVID-19 Pandemic in Spain","authors":"V. Martínez","doi":"10.36648/1989-8436.21.12.159","DOIUrl":"https://doi.org/10.36648/1989-8436.21.12.159","url":null,"abstract":"We analyze the evolution of the COVID-19 pandemic in Spain. Several numerical methods and models are studied to understand how the evolution of this pandemic is referenced. We also justify the adjustments that we have made in order to interpret the public data supplied by the Spanish Government. Finally, we present some of the lessons learned so that we way carry out early actions when we are immersed in similar pandemics.","PeriodicalId":8142,"journal":{"name":"Archives of Clinical Microbiology","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82998162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Staining For Bacterial Detection","authors":"S. Asin","doi":"10.36648/1989-8436.21.12.152","DOIUrl":"https://doi.org/10.36648/1989-8436.21.12.152","url":null,"abstract":"","PeriodicalId":8142,"journal":{"name":"Archives of Clinical Microbiology","volume":"46 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80440600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Zika Virus: A Mosquito-Borne Flavivirus","authors":"Samuel fedel","doi":"10.36648/1989-8436.21.12.142","DOIUrl":"https://doi.org/10.36648/1989-8436.21.12.142","url":null,"abstract":"The Zika virus is part of the Flaviviridae family of viruses. It is transmitted by Aedes mosquitoes that are active during the day, such as A. Aegypti, A. Albopictus. Its name comes from the Ugandan Zika Forest, where, in 1947, the virus was first isolated. The species shares dengue, yellow fever, Japanese encephalitis and West Nile viruses with the Zika virus. There are sometimes no or only mild signs of an infection known as Zika fever or Zika virus disease, similar to a very mild type of dengue fever.","PeriodicalId":8142,"journal":{"name":"Archives of Clinical Microbiology","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81932380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Saccharomyces: An Overview","authors":"S. Aaron","doi":"10.36648/1989-8436.21.12.162","DOIUrl":"https://doi.org/10.36648/1989-8436.21.12.162","url":null,"abstract":"","PeriodicalId":8142,"journal":{"name":"Archives of Clinical Microbiology","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78496317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial Note on Black Fungus","authors":"S. Aaron","doi":"10.36648/1989-8436.21.12.E001","DOIUrl":"https://doi.org/10.36648/1989-8436.21.12.E001","url":null,"abstract":"","PeriodicalId":8142,"journal":{"name":"Archives of Clinical Microbiology","volume":"65 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73384759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Biology of Plasmacytoid Dendritic Cells and their Role in Pathogenesis of Erythema Multiforme and Other Inflammatory Dermatoses: A Mini Literature Review","authors":"Hatice Zengin, B. Smoller","doi":"10.36648/1989-8436.21.12.160","DOIUrl":"https://doi.org/10.36648/1989-8436.21.12.160","url":null,"abstract":"Plasmacytoid Dendritic Cells (pDCs) are a unique dendritic cell population with both innate and adaptive immune functions. When pDCs get activated by various pathogens or self-DNA, they are able to produce massive amount of interferon type I and play an essential role in immune defense mechanisms. Plasmacytoid DCs are generally absent from the normal skin. In the past decade, their involvement in pathogenesis of different inflammatory dermatoses has been widely explored. Plasmacytoid DCs’ excessive sensing of non-self or self-DNA (upon skin injury) was addressed as a primary trigger for many cutaneous pathologies. Recently, we have also shown significant amount of pDCs in erythema multiforme lesions and hypothesized that these cells are central to EM pathogenesis as well. However, neither EM pathogenesis nor pDCs’ actual role in this entity is well studied. In this mini review, our goal is to outline recent updates on pDCs and their role in particular inflammatory skin diseases such as psoriasis. Our focus will also be the highlights of our recent study and our perspective regarding relationship between pDCs and EM.","PeriodicalId":8142,"journal":{"name":"Archives of Clinical Microbiology","volume":"89 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87366616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}