Dillon J. Dzikowicz, Mehmed Aktas, Betty Mykins, Xiaojuan Xia, Wojciech Zareba, Jean-Phillippe Couderc
{"title":"Identifying Demographic Factors Affecting the ECG Duration Collected Using a Single-Lead ECG Patch Device","authors":"Dillon J. Dzikowicz, Mehmed Aktas, Betty Mykins, Xiaojuan Xia, Wojciech Zareba, Jean-Phillippe Couderc","doi":"10.1111/anec.70068","DOIUrl":"https://doi.org/10.1111/anec.70068","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Atrial fibrillation (AF), affecting 3% of the US adults, is the most common arrhythmia. While ambulatory electrocardiogram (ECG) monitoring is essential for AF detection, conventional technologies have diagnostic limitations due to AF's sporadic nature. ECG patches offer extended monitoring periods, though their effectiveness is primarily limited by deteriorating skin-electrode contact rather than battery or memory constraints.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This analysis reports our experience with the Zio ECG patch (iRhythm, San Francisco, CA) in 256 AF patients.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>We analyzed human and technical factors and their association with ECG recording duration using previously recorded data which employed the ECG patch as a reference. Descriptive statistics and logistic regression were used to identify associations.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Body mass index (BMI) was found to be an independent predictor of poorer compliance in a dose-dependent manner (<i>B</i> = −0.046, OR = 0.955, 95% CI: 0.916–0.996, <i>p</i> = 0.033). Loss of adhesive was the primary reason for poor compliance (<i>n</i> = 25; 11%). These findings can guide researchers and clinicians in determining the appropriateness of a 14-day ECG patch based on expected wear time and patient compliance.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>BMI significantly impacts ECG patch compliance, primarily through adhesive failures. These findings indicate the need for improved adhesive technologies for higher BMI patients. Future device development should prioritize maintaining electrode-skin contact across diverse patient populations.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Trial Registration</h3>\u0000 \u0000 <p>ClinicalTrials.gov Identifier: NCT04267133</p>\u0000 </section>\u0000 </div>","PeriodicalId":8074,"journal":{"name":"Annals of Noninvasive Electrocardiology","volume":"30 3","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/anec.70068","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143904928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zhi Luo, Yi Liu, Yuwei Chen, Xiaobo Pu, Xiangbin Xiao
{"title":"Narrowed Right Bundle Branch Block Pattern in Tachycardia","authors":"Zhi Luo, Yi Liu, Yuwei Chen, Xiaobo Pu, Xiangbin Xiao","doi":"10.1111/anec.70072","DOIUrl":"https://doi.org/10.1111/anec.70072","url":null,"abstract":"<p>A 66-year-old man with 5-year intermittent palpitation underwent an electrophysiologic (EP) study. Electrocardiograms (ECGs) on admission showed sinus rhythm with right bundle branch block (RBBB). During palpitation, regular tachycardia with RBBB occurred. Through detailed analysis, the diagnosis of Wolff-Parkinson-White (WPW) syndrome with orthodromic atrio-ventricular reentry tachycardia (AVRT) was established. The case emphasizes the significance of comparing sinus rhythm and tachycardia ECGs for accurate diagnosis.</p>","PeriodicalId":8074,"journal":{"name":"Annals of Noninvasive Electrocardiology","volume":"30 3","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/anec.70072","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143883952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Case Report: Electrotonic Modulation-Related T-Wave Over-Sensing After Left Bundle Branch Pacing","authors":"Linlin Li, Manxin Lin, Jincun Guo, Qiang Li, Fanqi Meng, Xinyi Huang, Simei Chen, Binni Cai","doi":"10.1111/anec.70083","DOIUrl":"https://doi.org/10.1111/anec.70083","url":null,"abstract":"<p>A 66-year-old male patient diagnosed with dilated cardiomyopathy, heart failure with reduced EF (32%), and complete left bundle branch block (CLBBB) received cardiac resynchronization therapy (CRT)-D implantation. Left bundle branch pacing (LBBP) was successfully performed, but during the follow-up 6 weeks later, the electrocardiogram (ECG) showed a sinus rhythm tracked by ventricular pacing with a ratio of approximately 2:1 due to T-wave over-sensing, which might be caused by the changes in T-wave morphology due to electrotonic modulation and hyperkalemia or by the lower sensitivity threshold set by the auto sensing algorithm of the ICD. Shortening post-ventricular atrial refractory period (PVARP) restored the ventricular pacing tracking of the atrium, and the T-wave changes improved as time went by.</p>","PeriodicalId":8074,"journal":{"name":"Annals of Noninvasive Electrocardiology","volume":"30 3","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/anec.70083","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143879947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Murat Özmen, Onur Altunkaya, Selim Aydemir, Sidar Şiyar Aydın, Faruk Aydınyılmaz, Emrah Aksakal, Emre Alkan
{"title":"Evaluatıon of Depressıon and Anxıety Status in Patıents After Cardıac Devıce Implantatıon","authors":"Murat Özmen, Onur Altunkaya, Selim Aydemir, Sidar Şiyar Aydın, Faruk Aydınyılmaz, Emrah Aksakal, Emre Alkan","doi":"10.1111/anec.70085","DOIUrl":"https://doi.org/10.1111/anec.70085","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Implantable cardioverter defibrillator (ICD) and pacemaker (PM) implantation may lead to anxiety and depression, which may reduce patients' quality of life. The aim of our study was to compare depression and anxiety following device implantation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This prospective study was conducted on 202 patients admitted to our hospital with ICD and PM implants between January 2024 and January 2025.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The prevalence of anxiety in PM and ICD recipients was 25.9% and 38.8%, respectively. There was a significant difference in anxiety in ICD patients (< 0.001). In terms of depression, the results in the PM and ICD groups were 18.9 and 38.9, respectively. The results showed a significant difference in the prevalence of depression between PM and ICD recipients. The tendency toward depression was statistically significant in both device recipients (PM; <i>p</i> = 0.008, ICD; <i>p</i> < 0.001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Considering the prevalence of anxiety and depression, it seems necessary to pay closer attention to the anxiety and depression states of patients who have been treated with PM and ICD devices and to provide more widespread education to these patients.</p>\u0000 </section>\u0000 </div>","PeriodicalId":8074,"journal":{"name":"Annals of Noninvasive Electrocardiology","volume":"30 3","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/anec.70085","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143871640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Transesophageal Atrial Pacing for the Evaluation of Accessory Atrioventricular Pathways in Wolff-Parkinson-White Syndrome: A Pediatric Case Report and Literature Review","authors":"Jing Chen, Ping Zuo, Xiaoyun Yang, Bei Wang","doi":"10.1111/anec.70084","DOIUrl":"https://doi.org/10.1111/anec.70084","url":null,"abstract":"<p>Arrhythmia induction and identifying the functional characteristics of accessory pathways in Wolff-Parkinson-White (WPW) syndrome typically requires an invasive electrophysiological study. This case reports a 13-year-old boy with a five-year history of paroxysmal palpitations, where transesophageal atrial pacing (TEAP) was used to identify accessory pathways. TEAP revealed multiple tachycardia forms, differentiating orthodromic atrioventricular reentrant tachycardia with narrow and wide QRS complexes. EPS confirmed two pathways, diagnosing WPW syndrome. TEAP effectively assessed accessory pathways' functional characteristics and their roles in tachycardia, showcasing its potential as a minimally invasive diagnostic tool for this condition.</p>","PeriodicalId":8074,"journal":{"name":"Annals of Noninvasive Electrocardiology","volume":"30 3","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/anec.70084","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143861865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Effect of Sacubitril/Valsartan on Supraventricular and Ventricular Arrhythmias in Patients With Heart Failure","authors":"Alireza Arzhangzadeh, Mohammad Hossein Nikoo, Majid Haghjoo, Fatemeh Rasekh, Shayan Shojaei, Asma Mousavi, Salma Nozhat, Roozbeh Narimani-Javid, Helia Bazroodi, Sana Neisi, Mitra Mojibpour, Mohammad Abedini, Saghi Eslamzadeh, Hamed Bazrafshan Drissi, Sasan Shafiei","doi":"10.1111/anec.70081","DOIUrl":"https://doi.org/10.1111/anec.70081","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Patients with heart failure with reduced ejection fraction (HFrEF) frequently experience electrical disturbances, such as ventricular or atrial fibrillation (AF). Sacubitril/Valsartan (SV) therapy has been linked to lower rates of mortality, ventricular tachycardia (VT), and ventricular fibrillation (VF), with decreased reliance on implantable cardioverter-defibrillator (ICD) therapy. However, studies on the antiarrhythmic effects of SV in patients with ICD or cardiac resynchronization therapy defibrillator (CRT-D) devices are limited. This study aimed to evaluate the impact of SV therapy on antiarrhythmic pacing, defibrillation shock occurrences, and the burden of ventricular arrhythmias in patients with HFrEF who have ICD or CRT-D devices.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>This study was conducted at a HF outpatient clinic involving patients with HFrEF treated with SV. Primary outcomes included the incidence of VT, VF, non-sustained VT (NsVT), supraventricular tachycardia (SVT), and related interventions such as antiarrhythmic pacing (ATP) and defibrillation shocks.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Result</h3>\u0000 \u0000 <p>A total of 181 HFrEF patients completed at least 12 months of follow-up, with a mean age of 63.39 ± 12 years; 36.5% were male, and 60.8% had an ICD. Device interrogation revealed a significant reduction in VF incidents (7 vs. 15, <i>p</i> = 0.025) and a decrease in the combined outcome of VT and VF (17 vs. 24, <i>p</i> = 0.047). The need for ICD interventions such as ATP and shocks also significantly decreased following the initiation of SV therapy (10 vs. 24, <i>p</i> = 0.012).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>SV therapy significantly reduces the incidence of cardiac arrhythmias, particularly VT and VF, while decreasing the need for clinical interventions related to implanted devices.</p>\u0000 </section>\u0000 </div>","PeriodicalId":8074,"journal":{"name":"Annals of Noninvasive Electrocardiology","volume":"30 3","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/anec.70081","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143835773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adam Visca, Saadia Sherazi, Ilan Goldenberg, Scott McNitt, Nikhila Rao, Nilesh Rao, Ahmed Shah, Mehmet Aktas, Valentina Kutyifa, Wojciech Zareba, Krishna Rao
{"title":"Predicting Ventricular Tachyarrhythmias in Patients With Left Ventricular Ejection Fraction Improvement Following Cardiac Resynchronization Therapy","authors":"Adam Visca, Saadia Sherazi, Ilan Goldenberg, Scott McNitt, Nikhila Rao, Nilesh Rao, Ahmed Shah, Mehmet Aktas, Valentina Kutyifa, Wojciech Zareba, Krishna Rao","doi":"10.1111/anec.70059","DOIUrl":"https://doi.org/10.1111/anec.70059","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Patients undergoing cardiac resynchronization therapy with a defibrillator (CRT-D) often experience improvements in the left ventricular ejection fraction (LVEF). This study aimed to identify predictors of ventricular tachyarrhythmias (VTA) in patients with CRT-D devices and LVEF improvement beyond guideline recommendations for a defibrillator.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Patients randomized to the CRT-D arm of the Multicenter Automatic Defibrillator Implantation Trial With Cardiac Resynchronization Therapy trial who improved their LVEF to > 35% at 12 months following CRT-D implant were included in this analysis (<i>N</i> = 651). Predictors of an appropriate implantable cardioverter defibrillator (ICD) Rx VTA were evaluated by Cox proportional hazards regression modeling.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>We identified three predictors of VTA among patients treated with CRT-D subsequent to LVEF improvement > 35%: Lower range improvement in LVEF 36%–40% versus improvement to > 40% (HR, 1.97; 95% CI, 1.21–3.20; <i>p</i> = 0.006); Baseline non-LBBB ECG morphology (hazard ratio [HR], 1.93; 95% confidence interval [CI], 1.23–3.04; <i>p</i> = 0.004); Occurrence of VTA during the first year post-CRT-D (HR, 4.91; 95% CI, 2.99–8.07; <i>p</i> < 0.001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>We identified a sub-group of patients with risk factors who remain at high risk of VTA despite improvement in LVEF following CRT implant. These patients require close monitoring despite improvement in LVEF beyond guideline recommendations for an ICD.</p>\u0000 </section>\u0000 </div>","PeriodicalId":8074,"journal":{"name":"Annals of Noninvasive Electrocardiology","volume":"30 3","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/anec.70059","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143793338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ramazan Astan, Fehmi Kacmaz, Ersin Saricam, Erdogan Ilkay
{"title":"The Evaluation of P-Wave Parameters in Patients With Percutaneous Closure of Atrial Septal Defect","authors":"Ramazan Astan, Fehmi Kacmaz, Ersin Saricam, Erdogan Ilkay","doi":"10.1111/anec.70076","DOIUrl":"https://doi.org/10.1111/anec.70076","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Atrial septal defect (ASD) can lead to volume overload and related changes in P-wave parameters in surface electrocardiograms of these patients. In this study, we aimed to evaluate the effect of volume overload on P-wave parameters in patients with ASD.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>This study is a retrospective cohort analysis. A total of 142 patients with secundum ASD who underwent percutaneous closure were evaluated. P-wave duration (Pmax) and P-wave dispersion (PWD) were measured on the surface ECG before and 1 h after the closure procedure. We evaluated P-wave parameters in terms of defect size, duration of the volume overload, and closure device sizes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Pmax and PWD were significantly decreased after the procedure compared with the values before the procedure (<i>p</i> < 0.001). Pmax values had a statistically significant correlation with ASD size (< 20 mm or ≥ 20 mm) both before and after the procedure. Pmax values were significantly higher in patients older than 30 years of age (119.6 ± 19.5 vs. 102.7 ± 17.1 ms, respectively; <i>p</i> = 0.039). A significantly positive correlation was found between pre- and post-procedural Pmax and defect sizes (<i>r</i> = 0.474, <i>p</i> = 0.019 and <i>r</i> = 0.4233, <i>p</i> = 0.04, respectively). However, no positive correlation between PWD and defect age and size was present.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Percutaneous closure of ASD is associated with an immediate decrease in both Pd and Pmax that seems to be related to the acute volume overload cessation in cardiac chambers.</p>\u0000 </section>\u0000 </div>","PeriodicalId":8074,"journal":{"name":"Annals of Noninvasive Electrocardiology","volume":"30 3","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/anec.70076","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143793339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Refining STEMI Prognosis: Expanding the Role of Noninvasive Cardiac Monitoring Beyond the GRACE Score","authors":"Javeria Akhter, Javed Iqbal","doi":"10.1111/anec.70078","DOIUrl":"https://doi.org/10.1111/anec.70078","url":null,"abstract":"<p>We read with great interest the recent article by Xin et al. “Predictive Value of Noninvasive Cardiac Function Monitoring Combined with GRACE Score for Short-Term Outcomes in Patients With ST-Segment Elevation Myocardial Infarction” which provides valuable insights into the potential of noninvasive cardiac function monitoring (NCFM) to augment risk stratification in patients with ST-segment elevation myocardial infarction (STEMI). The authors present a novel approach to improving prognostic accuracy for major adverse cardiovascular events (MACE) by integrating hemodynamic parameters with the established GRACE score (Xin et al. <span>2025</span>). Although the study contributes implicitly to the field, certain aspects warrant further discussion.</p><p>First, the study successfully demonstrates that stroke volume (SV), cardiac output (CO), cardiac index (CI), contractility index (CTI), early diastolic filling ratio (EDFR), end-diastolic volume (EDV), and systemic vascular resistance (SVR) are independent predictors of MACE. Moreover, the authors confirm that including SV and CTI into the GRACE score improves predictive performance. While this finding is promising, the study does not assess whether alternative combinations of hemodynamic parameters might offer even greater predictive accuracy. Considering the interaction of different cardiac function parameters, an exploratory analysis using machine-learning techniques such as decision trees or neural networks could help investigate the most effective predictors of short-term outcomes (Patel and Sengupta <span>2020</span>).</p><p>Second, while the study effectively underscores the added predictive value of NCFM in combination with the GRACE score, it does not provide adequate discussion on the probability of integrating NCFM into clinical practice. Extensive implementation of noninvasive cardiac monitoring entails considerations such as availability, cost-effectiveness, and user-friendliness in different healthcare settings (Kim et al. <span>2019</span>). Addressing these logistical concerns would enhance the study's clinical applicability and guide its possible adoption in routine patient management.</p><p>Third, the study does not consider probable confounding variables that may affect the predictive power of NCFM. Variables such as renal function, medication adherence, and previous cardiovascular interventions could affect both hemodynamic parameters and MACE outcomes (Chinwong et al. <span>2021</span>; Hussain et al. <span>2023</span>). Adjusting for these factors in a multivariate analysis would support the study's conclusions and provide more precise risk stratification.</p><p>Fourth, the study does not investigate the additional benefit of repeated NCFM measurements over time. Although the single-timepoint evaluation at admission provides valuable prognostic information, dynamic changes in cardiac function parameters post-STEMI may offer supplementary predictive value. Future research shou","PeriodicalId":8074,"journal":{"name":"Annals of Noninvasive Electrocardiology","volume":"30 3","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/anec.70078","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143786876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}