{"title":"On the road with HIV: a guide for positive travelers.","authors":"Amelia Glynn","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":80644,"journal":{"name":"BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation","volume":"19 4","pages":"40-5"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27109672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Renal complications of HIV/AIDS.","authors":"Lynda Anne Szczech","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Renal complications are common among people living with HIV; in fact, up to 30% of HIV positive individuals may have protein in their urine--a sign of kidney dysfunction. It is difficult to estimate precisely how many people develop kidney disease--and, therefore, to implement effective disease prevention or early intervention--because kidney dysfunction may be asymptomatic or may result in only vague symptoms, such as fatigue or general malaise. Without specific symptoms, many individuals are diagnosed later in their disease course, reducing the efficacy of available treatments. Given the risks associated with kidney disease, developing awareness of kidney function and getting the necessary tests are essential to maintaining good health with HIV. This article explains how kidney function is assessed, describes the renal complications that are most commonly seen in HIV positive people, and outlines treatment options.</p>","PeriodicalId":80644,"journal":{"name":"BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation","volume":"19 4","pages":"27-34"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27109668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Conquering anxiety.","authors":"Joni Lavick, Gaetano Vaccaro","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":80644,"journal":{"name":"BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation","volume":"19 2","pages":"20-8"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26711752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"New approaches to HIV prevention.","authors":"Liz Highleyman","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Just as the 1996 International AIDS Conference in Vancouver ushered in the era of effective combination antiretroviral therapy and the 2000 meeting in Durban focused on the HIV/AIDS epidemic in the developing world, the 2006 conference (held August 13-18 in Toronto) may be remembered as the one that brought HIV prevention to the fore. Political considerations aside, it has become abundantly clear that efforts to promote behavioral change--the so-called \"ABC\" approach, relying on abstinence, marital fidelity (\"be faithful\"), and condoms--has failed to stem the tide of new HIV infections. According to the Joint United Nations Programme on HIV/AIDS (UNAIDS), some four million people worldwide were newly infected in 2005. Even as antiretroviral therapy begins to trickle down to people in resource-limited countries, public health experts estimate that about four people become infected with HIV for each person who starts treatment.</p>","PeriodicalId":80644,"journal":{"name":"BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation","volume":"19 2","pages":"29-38"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26711753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Human papillomavirus.","authors":"Liz Highleyman","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A majority of sexually active adults carry the human papillomavirus (HPV), but until recently, this virus received little public attention. This changed in 2006 with the approval of a new vaccine that can prevent infection with certain types of HPV, and thereby reduce the risk of cervical cancer.</p>","PeriodicalId":80644,"journal":{"name":"BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation","volume":"19 4","pages":"35-9"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27109669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"TH9507: an experimental treatment for lipodystrophy.","authors":"Anne Monroe","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>As the use of highly active antiretroviral therapy (HAART) became widespread, HIV positive individuals and their physicians began to notice changes in body fat distribution, with excess fat or fat loss noted in different areas. These body shape changes are sometimes accompanied by metabolic abnormalities, such as insulin resistance and elevated blood fats. Collectively, these changes are known as lipodystrophy syndrome. Treatment options for lipodystrophy are somewhat limited. Growth hormone has been used with success in clinical trials to reduce visceral adipose tissue, fat that collects around the abdominal organs. A new product, TH9507, a synthetic growth hormone releasing hormone analog made by the Canadian pharmaceutical company Theratechnologies, is currently showing promise in clinical trials and may represent a new treatment option for people with some types of lipodystrophy.</p>","PeriodicalId":80644,"journal":{"name":"BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation","volume":"19 4","pages":"16-9"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27109664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Revisiting monotherapy: heresy or revised orthodoxy?","authors":"Bob Huff","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>After the widespread introduction of triple combination antiretroviral therapy in 1996 caused AIDS deaths to plummet, the earlier practice of single-drug treatment--or monotherapy--seemed like an embarrassing phase of medical ignorance. By then, it had become all too apparent that monotherapy promoted the rapid development of drug-resistant virus, often leading to treatment failure. Stories still occasionally surface about an isolated doctor prescribing solo AZT (zidovudine, Retrovir), and many long-time HIV physicians with large practices probably have one or two patients still doing well on two drugs and see no reason to change their regimens. But by and large, hitting hard with two nucleoside reverse transcriptase inhibitors (NRTIs) plus either a protease inhibitor (PI) or a non-NRTI (NNRTI) has become dogma, and is now enshrined in all HIV treatment guidelines.</p>","PeriodicalId":80644,"journal":{"name":"BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation","volume":"18 2","pages":"15-7"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25969506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"MK-0518 and GS-9137: two promising integrase inhibitors in the pipeline.","authors":"Reilly O'Neal","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Possibly the most exciting news to come out of the 13th Conference on Retroviruses and Opportunistic Infections, held in Denver last February, concerned clinical trials of two experimental drugs in a new class: integrase inhibitors. If successful in further trials, integrase inhibitors could revitalize the treatment regimens of people living with multidrug-resistant HIV.</p>","PeriodicalId":80644,"journal":{"name":"BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation","volume":"18 4","pages":"13-6"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26290899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Methamphetamine and HIV.","authors":"Bob Huff","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>When the New York City Department of Health and Mental Hygiene announced in January 2005 that a gay man in his forties had become infected with a multidrug-resistant \"superstrain\" of HIV and had progressed to AIDS within a few months, much was made of the man's use of methamphetamine. The case highlighted two important aspects of the intersection of methamphetamine use and HIV. First is the fairly well-established role the drug can play in facilitating new infections by lowering users' inhibitions and encouraging sexual practices that increase the risk of HIV transmission. The second aspect is the idea that methamphetamine somehow speeds up the HIV disease process. There is little evidence of a direct interaction between meth and HIV that accelerates immune decline, but meth use can undermine the general health of the user. There is also a growing body of evidence that meth's harmful effects on the brain may be exacerbated in people with HIV, and that many HIV-related neurological impairments may be worsened by meth use.</p>","PeriodicalId":80644,"journal":{"name":"BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation","volume":"18 4","pages":"42-7"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26290903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Switching antiretroviral therapy.","authors":"Liz Highleyman","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":80644,"journal":{"name":"BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation","volume":"18 4","pages":"17-29"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26290900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}