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Annals of Pediatric Cardiology最新文献

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Effects of intranasal dexmedetomidine versus intranasal midazolam as premedication in children with tetralogy of Fallot undergoing corrective cardiac surgery: A randomized trial. 法洛四联症患儿接受心脏矫正手术时，鼻内注射右美托咪定与鼻内注射咪达唑仑作为术前用药的效果：随机试验。
IF 0.9
Annals of Pediatric Cardiology Pub Date : 2024-03-01 Epub Date: 2024-07-20 DOI: 10.4103/apc.apc_10_24
Sarvesh Srivastava, Sambhunath Das, Neeti Makhija, Sandeep Chauhan
{"title":"Effects of intranasal dexmedetomidine versus intranasal midazolam as premedication in children with tetralogy of Fallot undergoing corrective cardiac surgery: A randomized trial.","authors":"Sarvesh Srivastava, Sambhunath Das, Neeti Makhija, Sandeep Chauhan","doi":"10.4103/apc.apc_10_24","DOIUrl":"10.4103/apc.apc_10_24","url":null,"abstract":"<p><strong>Background: </strong>This prospective, randomized, double-blind trial was done to compare intranasal dexmedetomidine and intranasal midazolam as premedication for sedation and ease of child-parent separation in pediatric patients of tetralogy of Fallot (TOF) undergoing corrective cardiac surgery.</p><p><strong>Materials and methods: </strong>Forty children with TOF, between 1 and 10 years, undergoing corrective cardiac surgery were included in the study and, after randomization, were given intranasal midazolam (0.2 mg/kg) or intranasal dexmedetomidine (1 µg/kg), 30 min before shifting to the operation room (OR). Patients were assessed for sedation and child-parent separation, along with hemodynamic parameters, respiratory rate, and oxygen saturation (SpO2) 30 min after drug administration, at the time of shifting inside the OR, and at the time of induction of anesthesia.</p><p><strong>Results: </strong>Both groups had comparable child-parent scores, hemodynamic parameters, SpO2, and respiratory rate. However, the dexmedetomidine group had significantly better sedation levels than the midazolam group patients at the time of shifting inside the OR (dexmedetomidine group: 3.55 ± 0.82 vs. midazolam group: 2.80 ± 0.83; <i>P</i> = 0.007) and at the time of induction of anesthesia (dexmedetomidine group: 3.40 ± 0.75 vs. midazolam group: 2.70 ± 0.86; P = 0.009).</p><p><strong>Conclusion: </strong>Intranasal dexmedetomidine provides better sedation than midazolam, with similar child-parent separation scores and hemodynamic parameters, respiratory rate, and SpO2. No adverse events were observed in both groups. A study on a larger population will help in further establishing the safety and superiority of dexmedetomidine and will further its regular use as an intranasal premedication.</p>","PeriodicalId":8026,"journal":{"name":"Annals of Pediatric Cardiology","volume":"17 2","pages":"109-115"},"PeriodicalIF":0.9,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11343385/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142054740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Zero-contrast transcatheter closure of sinus venosus defect in advanced renal failure. 晚期肾衰竭患者窦静脉缺损的零对比经导管闭合术。
IF 0.9
Annals of Pediatric Cardiology Pub Date : 2024-03-01 Epub Date: 2024-07-20 DOI: 10.4103/apc.apc_29_24
Puthiyedath Thejaswi, Pramod Sagar, Kothandam Sivakumar
{"title":"Zero-contrast transcatheter closure of sinus venosus defect in advanced renal failure.","authors":"Puthiyedath Thejaswi, Pramod Sagar, Kothandam Sivakumar","doi":"10.4103/apc.apc_29_24","DOIUrl":"10.4103/apc.apc_29_24","url":null,"abstract":"<p><p>Transcatheter closure of sinus venosus defect (SVD) is an emerging intervention that utilizes a covered stent to redirect the right upper pulmonary vein to the left atrium. Preprocedural computed tomography analysis, as well as the interventional procedure, necessitates the use of radiographic contrast media. Contrast use is prohibited in patients with advanced kidney disease, who also carry high surgical risks of cardiopulmonary bypass. Transesophageal echocardiography-guided catheter intervention with zero contrast use is presented in this report, along with technical details about planning the procedure. Covered stent exclusion of SVD without contrast use has not been reported in the literature so far.</p>","PeriodicalId":8026,"journal":{"name":"Annals of Pediatric Cardiology","volume":"17 2","pages":"141-145"},"PeriodicalIF":0.9,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11343390/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142054748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Artificial intelligence-based model for automatic real-time and noninvasive estimation of blood potassium levels in pediatric patients. 基于人工智能的儿科患者血钾水平实时无创自动估算模型。
IF 0.9
Annals of Pediatric Cardiology Pub Date : 2024-03-01 Epub Date: 2024-07-20 DOI: 10.4103/apc.apc_54_24
Hamid Mokhtari Torshizi, Negar Omidi, Mohammad Rafie Khorgami, Razieh Jamali, Mohsen Ahmadi
{"title":"Artificial intelligence-based model for automatic real-time and noninvasive estimation of blood potassium levels in pediatric patients.","authors":"Hamid Mokhtari Torshizi, Negar Omidi, Mohammad Rafie Khorgami, Razieh Jamali, Mohsen Ahmadi","doi":"10.4103/apc.apc_54_24","DOIUrl":"10.4103/apc.apc_54_24","url":null,"abstract":"<p><strong>Background: </strong>An abnormal variation in blood electrolytes, such as potassium, contributes to mortality in children admitted to intensive care units. Continuous and real-time monitoring of potassium serum levels can prevent fatal arrhythmias, but this is not currently practical. The study aims to use machine learning to estimate blood potassium levels with accuracy in real time noninvasively.</p><p><strong>Methods: </strong>Hospitalized patients in the Pediatric Department of the Rajaie Cardiology and Medical Research Center and Tehran Heart Center were recruited from December 2021 to June 2022. The electrocardiographic (ECG) features of patients were evaluated. We defined 16 features for each signal and extracted them automatically. The dimension reduction operation was performed with the assistance of the correlation matrix. Linear regression, polynomials, decision trees, random forests, and support vector machine algorithms have been used to find the relationship between characteristics and serum potassium levels. Finally, we used a scatter plot and mean square error (MSE) to display the results.</p><p><strong>Results: </strong>Of 463 patients (mean age: 8 ± 1 year; 56% boys) hospitalized, 428 patients met the inclusion criteria, with 35 patients having a high noise of ECG were excluded. After the dimension reduction step, 11 features were selected from each cardiac signal. The random forest regression algorithm showed the best performance with an MSE of 0.3.</p><p><strong>Conclusion: </strong>The accurate estimation of serum potassium levels based on ECG signals is possible using machine learning algorithms. This can be potentially useful in predicting serum potassium levels in specific clinical scenarios.</p>","PeriodicalId":8026,"journal":{"name":"Annals of Pediatric Cardiology","volume":"17 2","pages":"116-123"},"PeriodicalIF":0.9,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11343398/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142054735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rescue one-stage hybrid perventricular and percutaneous device closure of multiple muscular ventricular septal defects using the new multifunctional occluder. 使用新型多功能闭塞器对多发肌性室间隔缺损进行一期混合室间隔和经皮装置闭合的抢救性治疗。
IF 0.9
Annals of Pediatric Cardiology Pub Date : 2024-03-01 Epub Date: 2024-07-20 DOI: 10.4103/apc.apc_16_24
Paul Padovani, Mohamedou Ly, Alban-Elouen Baruteau
{"title":"Rescue one-stage hybrid perventricular and percutaneous device closure of multiple muscular ventricular septal defects using the new multifunctional occluder.","authors":"Paul Padovani, Mohamedou Ly, Alban-Elouen Baruteau","doi":"10.4103/apc.apc_16_24","DOIUrl":"10.4103/apc.apc_16_24","url":null,"abstract":"<p><p>Data on the safety and efficiency of perventricular device closure of complex ventricular septal defects (VSDs) are scarce. We report successful one-stage combined hybrid perventricular and percutaneous closure of the muscular VSDs in a critically ill 4-kg infant, using the new multifunctional occluder.</p>","PeriodicalId":8026,"journal":{"name":"Annals of Pediatric Cardiology","volume":"17 2","pages":"146-148"},"PeriodicalIF":0.9,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11343388/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142054745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dual-drainage pulmonary venous return of the left upper lobe. 左上叶双引流肺静脉回流。
IF 0.9
Annals of Pediatric Cardiology Pub Date : 2024-03-01 Epub Date: 2024-07-20 DOI: 10.4103/apc.apc_8_24
Yeka W Nmadu, Robert F English
{"title":"Dual-drainage pulmonary venous return of the left upper lobe.","authors":"Yeka W Nmadu, Robert F English","doi":"10.4103/apc.apc_8_24","DOIUrl":"10.4103/apc.apc_8_24","url":null,"abstract":"<p><p>Dual drainage of a pulmonary vein is an unusual anomaly of pulmonary venous drainage. While being evaluated for hypertension, a child was found with dual drainage of the upper left lobe through a vertical vein that connects to the normal pulmonary vein as well as the innominate vein with no symptoms from his effective left-to-right shunt.</p>","PeriodicalId":8026,"journal":{"name":"Annals of Pediatric Cardiology","volume":"17 2","pages":"156-158"},"PeriodicalIF":0.9,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11343391/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142054739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dual dilemma: Necrotizing enterocolitis and congenital heart disease in infants. 双重困境：婴儿坏死性小肠结肠炎和先天性心脏病。
IF 0.9
Annals of Pediatric Cardiology Pub Date : 2024-03-01 Epub Date: 2024-07-20 DOI: 10.4103/apc.apc_46_24
Maryum Imran, Javeria Kamran, Rida Irfan, Noor Ul Huda, Ahmad Akhtar
{"title":"Dual dilemma: Necrotizing enterocolitis and congenital heart disease in infants.","authors":"Maryum Imran, Javeria Kamran, Rida Irfan, Noor Ul Huda, Ahmad Akhtar","doi":"10.4103/apc.apc_46_24","DOIUrl":"10.4103/apc.apc_46_24","url":null,"abstract":"","PeriodicalId":8026,"journal":{"name":"Annals of Pediatric Cardiology","volume":"17 2","pages":"159-160"},"PeriodicalIF":0.9,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11343396/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142054738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The arrangement of the organs. 器官的排列。
IF 0.9
Annals of Pediatric Cardiology Pub Date : 2024-03-01 Epub Date: 2024-07-20 DOI: 10.4103/apc.apc_107_24
Robert Henry Anderson
{"title":"The arrangement of the organs.","authors":"Robert Henry Anderson","doi":"10.4103/apc.apc_107_24","DOIUrl":"10.4103/apc.apc_107_24","url":null,"abstract":"","PeriodicalId":8026,"journal":{"name":"Annals of Pediatric Cardiology","volume":"17 2","pages":"132-133"},"PeriodicalIF":0.9,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11343392/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142054746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transcatheter management of superior vena cava obstruction following cardiac surgery: A case report from a resource-limited set-up. 心脏手术后上腔静脉阻塞的经导管治疗：来自资源有限地区的病例报告。
IF 0.9
Annals of Pediatric Cardiology Pub Date : 2024-03-01 Epub Date: 2024-07-20 DOI: 10.4103/apc.apc_34_24
Nurul Islam, Siddhartha Saha
{"title":"Transcatheter management of superior vena cava obstruction following cardiac surgery: A case report from a resource-limited set-up.","authors":"Nurul Islam, Siddhartha Saha","doi":"10.4103/apc.apc_34_24","DOIUrl":"10.4103/apc.apc_34_24","url":null,"abstract":"<p><p>Obstruction of the superior vena cava (SVC) is a rare complication after cardiac surgery in infants and children. We present the case of an 8-year-old boy who underwent bi-directional Glenn shunt followed by takedown of Glenn shunt and complete repair for cyanotic congenital heart disease. After 4 years of surgery, the child developed features of superior vena caval (SVC) syndrome. Echocardiography and CT angiography revealed complete obstruction of SVC without any forward flow. Transcatheter intervention was performed successfully to re-canalize and stent the SVC to maintain its patency. The patient was doing well at follow-up appointments, with good laminar flow through the stent. In conclusion, transcatheter management of post cardiac surgery SVC obstruction was successful in this patient.</p>","PeriodicalId":8026,"journal":{"name":"Annals of Pediatric Cardiology","volume":"17 2","pages":"152-155"},"PeriodicalIF":0.9,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11343395/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142054747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mitral annular disjunction with atrial septal defect in children: An intriguing association. 儿童二尖瓣环脱节与房间隔缺损：一种耐人寻味的关联。
IF 0.9
Annals of Pediatric Cardiology Pub Date : 2024-03-01 Epub Date: 2024-07-20 DOI: 10.4103/apc.apc_35_24
Mridul Agarwal, Jay Relan, Neeraj Aggarwal, Raja Joshi
{"title":"Mitral annular disjunction with atrial septal defect in children: An intriguing association.","authors":"Mridul Agarwal, Jay Relan, Neeraj Aggarwal, Raja Joshi","doi":"10.4103/apc.apc_35_24","DOIUrl":"10.4103/apc.apc_35_24","url":null,"abstract":"<p><p>Mitral annular disjunction (MAD) is defined as a separation between the mitral annulus and the left ventricular myocardium and is most often seen in association with mitral valve prolapse (MVP). MAD has been linked to ventricular arrhythmias in adults, independent of MVP. However, it has rarely been reported in children. We, hereby, report two cases of MAD associated with a large atrial septal defect (ASD). Thus far, there are no consensus guidelines for the management of MAD. The additional association of large ASD further complicates the decision-making in these patients. To the best of our knowledge, this is the first report of the association of MAD with ASD. We further discuss the challenges in the management of this condition.</p>","PeriodicalId":8026,"journal":{"name":"Annals of Pediatric Cardiology","volume":"17 2","pages":"137-140"},"PeriodicalIF":0.9,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11343393/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142054742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Regenerating the ailing heart: Stem cell therapies for hypoplastic left heart syndrome. 再生生病的心脏：干细胞疗法治疗左心发育不全综合征。
IF 0.9
Annals of Pediatric Cardiology Pub Date : 2024-03-01 Epub Date: 2024-07-20 DOI: 10.4103/apc.apc_24_24
Udit Choubey, Varsha Srinivas, Yash Vardhan Trivedi, Nikita Garg, Vasu Gupta, Rohit Jain
{"title":"Regenerating the ailing heart: Stem cell therapies for hypoplastic left heart syndrome.","authors":"Udit Choubey, Varsha Srinivas, Yash Vardhan Trivedi, Nikita Garg, Vasu Gupta, Rohit Jain","doi":"10.4103/apc.apc_24_24","DOIUrl":"10.4103/apc.apc_24_24","url":null,"abstract":"<p><p>Hypoplastic left heart syndrome (HLHS) is a complex congenital heart defect (CHD) characterized by a spectrum of underdeveloped left-sided cardiac structures. It is a serious defect and warrants either 3-staged surgical palliation or a heart transplant. Despite numerous surgical advancements, long-term outcomes remain challenging and still have significant morbidity and mortality. There have been notable advancements in stem cell therapy for HLHS, including developments in diverse stem cell origins and methods of administration. Clinical trials have shown safety and potential benefits, including improved ventricular function, reduced heart failure, and fewer adverse events. Younger myocardium seems particularly receptive to stem cell signals, suggesting the importance of early intervention. This review explores the potential of emerging stem cell-based therapies as an adjunctive approach to improve the outcomes for HLHS patients.</p>","PeriodicalId":8026,"journal":{"name":"Annals of Pediatric Cardiology","volume":"17 2","pages":"124-131"},"PeriodicalIF":0.9,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11343389/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142054744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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