{"title":"The additive effect of latanoprost 0.005% in patients on maximally tolerated medical therapy","authors":"Shari E. Strier","doi":"10.1016/S0953-4431(97)10015-7","DOIUrl":"10.1016/S0953-4431(97)10015-7","url":null,"abstract":"<div><p><em>Objective:</em> To determine the IOP lowering effect of latanoprost 0.005% when added to patients already on maximum tolerated medical therapy and not at target IOP. <em>Design:</em> Eye Clinic records of glaucoma patients at the Baltimore VAMC who were on maximum tolerated medical therapy and who had latanoprost 0.005% added to their drug regimen due to unacceptably high IOP levels were reviewed. The 18 patients whose findings were analyzed for this study were all male veterans ranging in age from 53 to 82 years. The mean age was 73.3 years. All but one of the subjects were African-American. Three baseline IOP readings were taken before patients were started on latanoprost. Patients were then followed at their regular appointments and the resultant change in intraocular pressure was assessed. Statistical significance was determined by Student's <em>t</em>-test and by defining the correlation coefficient. <em>Results:</em> The addition of latanoprost 0.005% additionally lowered IOP by an average of 21% for patients already on maximum tolerated medical therapy. This effect was statistically significant at <em>P < 0.01</em>. Seventy-two percent of the subjects reached their target IOPs. There was a trend toward higher IOP reduction with higher baseline IOP, but no direct correlation was found. There was a general decrease in the percentage of subjects reaching target pressures as the number of medications taken increased. Of those patients not on pilocarpine, a greater number reached their target pressures. The difference in the amount of patients reaching their target pressures on and off pilocarpine was mildly significant at <em>P</em> < 0.5. However, the difference in percentage drop in IOP between these two groups was not significant. <em>Conclusion:</em> This study indicated that latanoprost 0.005% was useful in lowering IOP in patients already on maximum tolerated medical therapy. A large percentage of patients taking pilocarpine as part of their drug regimen had a therapeutic lowering of IOP when latanoprost was added. This indicates there may be an additivity of latanoprost to pilocarpine when they are used together in clinical practice.</p></div>","PeriodicalId":80266,"journal":{"name":"Clinical eye and vision care","volume":"9 4","pages":"Pages 189-196"},"PeriodicalIF":0.0,"publicationDate":"1997-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0953-4431(97)10015-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56467254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Come see the new NECO!","authors":"","doi":"10.1016/S0953-4431(97)90020-5","DOIUrl":"https://doi.org/10.1016/S0953-4431(97)90020-5","url":null,"abstract":"","PeriodicalId":80266,"journal":{"name":"Clinical eye and vision care","volume":"9 4","pages":"Page 236"},"PeriodicalIF":0.0,"publicationDate":"1997-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0953-4431(97)90020-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136543187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bilateral idiopathic juxtafoveolar retinal telangiectasis","authors":"Keri M. Pomella","doi":"10.1016/S0953-4431(97)10018-2","DOIUrl":"10.1016/S0953-4431(97)10018-2","url":null,"abstract":"<div><p>Bilateral idiopathic juxtafoveolar retinal telangiectasis (JRT) is a condition of unknown etiology characterized by telangiectatic retinal vessels located temporal to the fovea. Most patients with bilateral JRT have associated telangiectasis, dilated capillaries, minimal exudation, retinal crystals, right angle venules, and retinal pigment hyperplasia. An unusual case of bilateral retinal telangiectasis with associated asymmetric cystoid macular edema in a middle-aged female is presented. This case is unusual due to the presence of cystoid macular edema. Classification, differential diagnosis and management of idiopathic juxtafoveolar retinal telangiectasis are reviewed.</p></div>","PeriodicalId":80266,"journal":{"name":"Clinical eye and vision care","volume":"9 4","pages":"Pages 213-219"},"PeriodicalIF":0.0,"publicationDate":"1997-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0953-4431(97)10018-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56467396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical assessment of bloody tears","authors":"Peter J. Calla O.D.","doi":"10.1016/S0953-4431(97)10016-9","DOIUrl":"10.1016/S0953-4431(97)10016-9","url":null,"abstract":"<div><p>Bloody tears are a rare clinical occurrence that can cause great anxiety for the patient and doctor alike. They can be associated with lesions of the lids, conjunctiva, cornea, lacrimal drainage system or lacrimal gland. Consideration should also be given to possible underlying systemic involvement. This paper includes a case presentation of a reported case of bloody tears and will review the differential diagnosis and management considerations in this condition.</p></div>","PeriodicalId":80266,"journal":{"name":"Clinical eye and vision care","volume":"9 4","pages":"Pages 197-201"},"PeriodicalIF":0.0,"publicationDate":"1997-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0953-4431(97)10016-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56467356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"1. Connecticut Association of Optometrists","authors":"Hal Ostrom O.D.","doi":"10.1016/S0953-4431(97)90016-3","DOIUrl":"10.1016/S0953-4431(97)90016-3","url":null,"abstract":"","PeriodicalId":80266,"journal":{"name":"Clinical eye and vision care","volume":"9 4","pages":"Page 234"},"PeriodicalIF":0.0,"publicationDate":"1997-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0953-4431(97)90016-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"93736256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mary Ann Skarote O.D. , Robert Newcomb O.D., M.P.H., FAAO
{"title":"Ocular histoplasmosis","authors":"Mary Ann Skarote O.D. , Robert Newcomb O.D., M.P.H., FAAO","doi":"10.1016/S0953-4431(97)10019-4","DOIUrl":"https://doi.org/10.1016/S0953-4431(97)10019-4","url":null,"abstract":"<div><p>Presumed ocular histoplasmosis syndrome, or POHS, is a disease which usually presents itself in the classic triad of clinical signs: peripapillary atrophy, peripheral ‘punched-out’ scarring, and a macular lesion. This paper describes two cases: one which is a classic case, and another which is an unusual presentation of the same disease.</p></div>","PeriodicalId":80266,"journal":{"name":"Clinical eye and vision care","volume":"9 4","pages":"Pages 221-225"},"PeriodicalIF":0.0,"publicationDate":"1997-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0953-4431(97)10019-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92077991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Quarterly reports of the New England council of optometrists","authors":"","doi":"10.1016/S0953-4431(97)90006-0","DOIUrl":"https://doi.org/10.1016/S0953-4431(97)90006-0","url":null,"abstract":"","PeriodicalId":80266,"journal":{"name":"Clinical eye and vision care","volume":"9 3","pages":"Page 179"},"PeriodicalIF":0.0,"publicationDate":"1997-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0953-4431(97)90006-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136672104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}