Clinical allergy and immunology最新文献_第9页

Differential diagnosis of persistent nonallergic rhinitis and rhinosinusitis syndromes. 持续性非过敏性鼻炎与鼻鼻窦炎综合征的鉴别诊断。

Clinical allergy and immunology Pub Date : 2007-01-01 DOI: 10.3109/9781420021172-7

M. Staevska, J. Baraniuk

引用次数: 12

Role of mast cells and basophils in chronic rhinosinusitis. 肥大细胞和嗜碱性粒细胞在慢性鼻窦炎中的作用。

Clinical allergy and immunology Pub Date : 2007-01-01 DOI: 10.3109/9781420014020-10

R. Pawankar, Kun‐Hee Lee, M. Nonaka, R. Takizawa

{"title":"Role of mast cells and basophils in chronic rhinosinusitis.","authors":"R. Pawankar, Kun‐Hee Lee, M. Nonaka, R. Takizawa","doi":"10.3109/9781420014020-10","DOIUrl":"https://doi.org/10.3109/9781420014020-10","url":null,"abstract":"Mast cells and basophils contribute to induction and/or maintenance of eosinophilic inflammation by a variety of mechanisms, including IgE-dependent and IgE-independent processes. The latter include a variety of stimuli that have only recently been elucidated, including mechanisms triggered by bacteria, virus, fungi, complement, or autoantibodies. MCs, and basophils contribute to inflammation both directly through the release of inflammatory mediators, cytokines and growth factors and indirectly through the activation of structural cells. Accumulating evidence places MCs (and most probably basophils) in a position of importance in the pathogenesis of CRS, particularly in the pathogenesis and progression of NP (Fig. 1). Mechanisms other than conventional IgE-dependent activation of MCs are intriguing as potential mechanisms of eosinophilic inflammation in non-allergic CRS/NP. Although it is not possible using current pharmacologic approaches to completely isolate the effects of MCs or basophils in CRS and NP pathogenesis, it seems most likely that such approaches will eventually be available. It might be expected that one or both of these cells will be shown to play important roles, particularly considering their potential for activation by IgE and non-IgE mechanisms, their production of a broad array of inflammatory mediators, cytokines and growth factors, and their unique assortment of proteases.","PeriodicalId":80264,"journal":{"name":"Clinical allergy and immunology","volume":"20 1","pages":"93-101"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69463538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 45

The role of nasal endoscopy in the diagnosis and medical management of chronic rhinosinusitis. 鼻内窥镜在慢性鼻窦炎诊断和医疗管理中的作用。

Clinical allergy and immunology Pub Date : 2007-01-01 DOI: 10.3109/9781420014020-17

C. Melroy, M. Dubin, B. Senior

引用次数: 4

Environmental and allergic factors in chronic rhinosinusitis. 慢性鼻窦炎的环境和过敏因素。

Clinical allergy and immunology Pub Date : 2007-01-01 DOI: 10.3109/9781420014020-7

J. Pinto, R. Naclerio

引用次数: 3

Aspirin-sensitive rhinosinusitis and asthma. 阿司匹林敏感性鼻窦炎和哮喘。

Clinical allergy and immunology Pub Date : 2007-01-01

Marek L Kowalski