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Polymer gel passes safety tests, and is set to deliver drugs 聚合物凝胶通过了安全测试，并将用于输送药物
Pharmaceutical science & technology today Pub Date : 2000-12-01 DOI: 10.1016/S1461-5347(00)00321-7
David Bradley
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引用次数: 0
Particulate characterization by ultrasound 超声颗粒表征
Pharmaceutical science & technology today Pub Date : 2000-11-01 DOI: 10.1016/S1461-5347(00)00310-2
Malcolm J.W Povey
{"title":"Particulate characterization by ultrasound","authors":"Malcolm J.W Povey","doi":"10.1016/S1461-5347(00)00310-2","DOIUrl":"10.1016/S1461-5347(00)00310-2","url":null,"abstract":"<div><p>Ultrasound is a technique that is capable of tremendous accuracy and precision, whether in the laboratory or on-line in the factory. Data acquisition rates of the order of kHz transform process monitoring, providing unprecedented information of high statistical value. Ultrasound is complementary to other measurement modalities, probing the elastic and thermal properties of materials. In the absence of air bubbles, ultrasound travels through concentrated systems of particles, providing information about size, compressibility, structure, distribution, chemical and phase state. It is safe, can be non-invasive and can be economical. In these respects, it is unique.</p></div>","PeriodicalId":80125,"journal":{"name":"Pharmaceutical science & technology today","volume":"3 11","pages":"Pages 373-380"},"PeriodicalIF":0.0,"publicationDate":"2000-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1461-5347(00)00310-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21916162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Breast cancer drug for women who fail to respond to tamoxifen 治疗对他莫昔芬无效的女性的乳腺癌药物
Pharmaceutical science & technology today Pub Date : 2000-11-01 DOI: 10.1016/S1461-5347(00)00307-2
David Bradley
{"title":"Breast cancer drug for women who fail to respond to tamoxifen","authors":"David Bradley","doi":"10.1016/S1461-5347(00)00307-2","DOIUrl":"10.1016/S1461-5347(00)00307-2","url":null,"abstract":"","PeriodicalId":80125,"journal":{"name":"Pharmaceutical science & technology today","volume":"3 11","pages":"Page 369"},"PeriodicalIF":0.0,"publicationDate":"2000-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1461-5347(00)00307-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21916158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Seroquel offers hope for bipolar patients 思瑞康为躁郁症患者带来了希望
Pharmaceutical science & technology today Pub Date : 2000-11-01 DOI: 10.1016/S1461-5347(00)00308-4
David Bradley
{"title":"Seroquel offers hope for bipolar patients","authors":"David Bradley","doi":"10.1016/S1461-5347(00)00308-4","DOIUrl":"10.1016/S1461-5347(00)00308-4","url":null,"abstract":"","PeriodicalId":80125,"journal":{"name":"Pharmaceutical science & technology today","volume":"3 11","pages":"Page 371"},"PeriodicalIF":0.0,"publicationDate":"2000-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1461-5347(00)00308-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21916160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Monitor: progress and profiles 监控:进度和概要文件
Pharmaceutical science & technology today Pub Date : 2000-11-01 DOI: 10.1016/S1461-5347(00)00312-6
Andrew W Lloyd , A.Christy Hunter , Monitor Editors
{"title":"Monitor: progress and profiles","authors":"Andrew W Lloyd ,&nbsp;A.Christy Hunter ,&nbsp;Monitor Editors","doi":"10.1016/S1461-5347(00)00312-6","DOIUrl":"10.1016/S1461-5347(00)00312-6","url":null,"abstract":"<div><p>Monitor provides an insight into the latest developments in pharmaceutical science and technology through brief synopses of recent presentations, publications and patents, and expert commentaries on the latest technologies. There are two sections: Progress summarizes the latest developments in pharmaceutical process technology, formulation, analytical technology, sterilization, controlled drug delivery systems and regulatory issues; Profiles offers expert commentary on emerging technologies, novel processes and strategic, organizational and logistic issues underlying pharmaceutical R&amp;D.</p></div>","PeriodicalId":80125,"journal":{"name":"Pharmaceutical science & technology today","volume":"3 11","pages":"Pages 393-397"},"PeriodicalIF":0.0,"publicationDate":"2000-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1461-5347(00)00312-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21916165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stem-cell infusion might reduce lupus deaths 干细胞输注可能减少狼疮死亡
Pharmaceutical science & technology today Pub Date : 2000-11-01 DOI: 10.1016/S1461-5347(00)00306-0
David Bradley
{"title":"Stem-cell infusion might reduce lupus deaths","authors":"David Bradley","doi":"10.1016/S1461-5347(00)00306-0","DOIUrl":"10.1016/S1461-5347(00)00306-0","url":null,"abstract":"","PeriodicalId":80125,"journal":{"name":"Pharmaceutical science & technology today","volume":"3 11","pages":"Page 370"},"PeriodicalIF":0.0,"publicationDate":"2000-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1461-5347(00)00306-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21916159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Delivering DNA with polymer matrices: applications in tissue engineering and gene therapy 用聚合物基质传递DNA:在组织工程和基因治疗中的应用
Pharmaceutical science & technology today Pub Date : 2000-11-01 DOI: 10.1016/S1461-5347(00)00305-9
Sara-Kaye Madsen , David J Mooney
{"title":"Delivering DNA with polymer matrices: applications in tissue engineering and gene therapy","authors":"Sara-Kaye Madsen ,&nbsp;David J Mooney","doi":"10.1016/S1461-5347(00)00305-9","DOIUrl":"10.1016/S1461-5347(00)00305-9","url":null,"abstract":"<div><p>DNA delivery from polymers is currently being applied to the multidisciplinary science of gene therapy and tissue engineering. This is motivated by the potential of treating a wide range of diseases and the provision of alternatives to tissue and organ transplantation. The combination of these fields involves the incorporation of genes into polymeric matrices that can be injected or implanted to promote tissue regeneration. This review presents an overview of current and developing polymer systems for gene delivery and tissue engineering.</p></div>","PeriodicalId":80125,"journal":{"name":"Pharmaceutical science & technology today","volume":"3 11","pages":"Pages 381-384"},"PeriodicalIF":0.0,"publicationDate":"2000-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1461-5347(00)00305-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21916163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 26
Development of a new engineering-based capsule for human drug absorption studies 用于人体药物吸收研究的新型工程胶囊的研制
Pharmaceutical science & technology today Pub Date : 2000-11-01 DOI: 10.1016/S1461-5347(00)00311-4
Ian Wilding , Peter Hirst , Alyson Connor
{"title":"Development of a new engineering-based capsule for human drug absorption studies","authors":"Ian Wilding ,&nbsp;Peter Hirst ,&nbsp;Alyson Connor","doi":"10.1016/S1461-5347(00)00311-4","DOIUrl":"10.1016/S1461-5347(00)00311-4","url":null,"abstract":"<div><p>Over recent years, there has been a significant growth in the number of new drugs entering development with challenging pharmaceutical (e.g. solubility) and biopharmaceutical (e.g. permeability) properties. As a consequence, there is an increasing number of pharmaceutical companies using human absorption studies to provide a ‘route map’ for development. These projects are typically undertaken early in clinical development and utilize engineering-based capsules to provide non-invasive drug delivery to the selected sites of the human gut. The Enterion capsule has recently been developed to provide for the delivery of a wide range of different drug formulations, for example, solution, powder and granulate, into any region of the gut, both easily and efficiently.</p></div>","PeriodicalId":80125,"journal":{"name":"Pharmaceutical science & technology today","volume":"3 11","pages":"Pages 385-392"},"PeriodicalIF":0.0,"publicationDate":"2000-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1461-5347(00)00311-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21916164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 121
Dual-function medication offers hope for asthma sufferers 双重功能药物为哮喘患者带来希望
Pharmaceutical science & technology today Pub Date : 2000-11-01 DOI: 10.1016/S1461-5347(00)00309-6
David Bradley
{"title":"Dual-function medication offers hope for asthma sufferers","authors":"David Bradley","doi":"10.1016/S1461-5347(00)00309-6","DOIUrl":"10.1016/S1461-5347(00)00309-6","url":null,"abstract":"","PeriodicalId":80125,"journal":{"name":"Pharmaceutical science & technology today","volume":"3 11","pages":"Page 372"},"PeriodicalIF":0.0,"publicationDate":"2000-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1461-5347(00)00309-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21916161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Alternative uses found for cancer drug 发现抗癌药物的替代用途
Pharmaceutical science & technology today Pub Date : 2000-10-01 DOI: 10.1016/S1461-5347(00)00299-6
David Bradley
{"title":"Alternative uses found for cancer drug","authors":"David Bradley","doi":"10.1016/S1461-5347(00)00299-6","DOIUrl":"10.1016/S1461-5347(00)00299-6","url":null,"abstract":"","PeriodicalId":80125,"journal":{"name":"Pharmaceutical science & technology today","volume":"3 10","pages":"Page 334"},"PeriodicalIF":0.0,"publicationDate":"2000-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1461-5347(00)00299-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21878158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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