Journal of women's health & gender-based medicine最新文献_第7页

Times change: the public and government. 时代变了:公众和政府。

Journal of women's health & gender-based medicine Pub Date : 2002-01-01 DOI: 10.1089/152460902753473372

F. Haseltine

引用次数: 4

A survey of gynecologists concerning menorrhagia: perceptions of bleeding disorders as a possible cause. 一项关于月经过多的妇科医生的调查:对出血性疾病作为可能原因的看法。

Journal of women's health & gender-based medicine Pub Date : 2002-01-01 DOI: 10.1089/152460902753473444

A. Dilley, C. Drews, C. Lally, H. Austin, Elizabeth R. Barnhart, B. Evatt

{"title":"A survey of gynecologists concerning menorrhagia: perceptions of bleeding disorders as a possible cause.","authors":"A. Dilley, C. Drews, C. Lally, H. Austin, Elizabeth R. Barnhart, B. Evatt","doi":"10.1089/152460902753473444","DOIUrl":"https://doi.org/10.1089/152460902753473444","url":null,"abstract":"We sought to determine perceptions and practices of American gynecologists when treating with a woman complaining of menorrhagia, specifically with regard to an underlying bleeding disorder as a potential cause. A mail survey of Georgia members of the American College of Obstetricians and Gynecologists was conducted. The survey response was 52%, and the analysis includes 376 physicians who reported seeing at least one gynecological patient per week. On average, respondents were in practice 20 years and reported that 8% of their patient population complain of menorrhagia. Virtually all physicians reported employing a menstrual history as a starting point for the workup for menorrhagia, and 95% order a hemoglobin/hematocrit determination. About 50% of physicians considered saturating three tampons/pads per 4 hours as excessive, although the criterion varied widely (range 0-24 per 4 hours, SD = 3). The diagnoses considered most likely among reproductive age women were anovulatory bleeding or benign lesions or that the heavy bleeding was within normal limits. Only 4% of physicians would consider von Willebrand disease (VWD) for this age group (women of reproductive age). Among girls near menarche, physicians overwhelmingly consider anovulatory bleeding or bleeding within normal limits the likely diagnoses, and 16% would consider VWD in this age group. Only rarely (3%) do surveyed physicians refer menorrhagia patients to other specialists. Most respondents believe that most menorrhagia is caused by anovulation or is within normal limits. Bleeding disorders are believed to be a rare cause of menorrhagia.","PeriodicalId":80044,"journal":{"name":"Journal of women's health & gender-based medicine","volume":"232 6","pages":"39-44"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/152460902753473444","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72392201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 70

Phytoestrogen and multiple vitamin/mineral effects on bone mineral density in early postmenopausal women: a pilot study. 植物雌激素和多种维生素/矿物质对早期绝经后妇女骨密度的影响:一项初步研究。

Journal of women's health & gender-based medicine Pub Date : 2002-01-01 DOI: 10.1089/152460902753473462

A. Cook, Gena Pennington

{"title":"Phytoestrogen and multiple vitamin/mineral effects on bone mineral density in early postmenopausal women: a pilot study.","authors":"A. Cook, Gena Pennington","doi":"10.1089/152460902753473462","DOIUrl":"https://doi.org/10.1089/152460902753473462","url":null,"abstract":"The purpose of the study was to assess the effect of a combination regimen of herbs, vitamins, and minerals on bone mineral density (BMD) in early postmenopausal women via a 2-year, single-blind, uncontrolled, prospective trial. BMD was measured by dual energy x-ray absorptiometry (DEXA) at baseline and at 6, 12, and 24 months. Results of lumbar spine, hip, and forearm densities did not differ significantly from historical controls derived from other recent trials using a similar patient population. Bone mineral losses are reported on an annualized basis over the 2 years for the 12 women who completed the trial: spine (-1.42% per year), hip (-0.43% per year), forearm (-1.42% per year). Six women were withdrawn from the trial by the investigators because of excessive losses of bone mineral, and 1 of these women was diagnosed with hyperparathyroidism. There were no metabolic diseases to explain the losses in the remaining 5 withdrawn subjects. Four of 21 subjects experienced adverse side effects, necessitating dropping out by 3 of these women. In conclusion, the combined treatment regimen of a menopause symptom-oriented herbal blend plus a high potency vitamin/mineral was unsuccessful in protecting women against the predictable acceleration of bone mineral losses associated with early postmenopause.","PeriodicalId":80044,"journal":{"name":"Journal of women's health & gender-based medicine","volume":"8 1","pages":"53-60"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84729603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 15

Are mammography and palpation sufficient for breast cancer screening? A dissenting opinion. 乳房x光检查和触诊是否足以进行乳腺癌筛查?反对意见。

Journal of women's health & gender-based medicine Pub Date : 2002-01-01 DOI: 10.1089/152460902753473417

L. Keith, J. Oleszczuk, M. Laguens

{"title":"Are mammography and palpation sufficient for breast cancer screening? A dissenting opinion.","authors":"L. Keith, J. Oleszczuk, M. Laguens","doi":"10.1089/152460902753473417","DOIUrl":"https://doi.org/10.1089/152460902753473417","url":null,"abstract":"Breast cancer is an equal opportunity killer in that as many as 60%-70% of breast cancer patients have no obvious risk factor(s). Thus, the continued reliance on the importance of risk factors to initiate screening programs may inhibit further inquiry into better diagnostic and prognostic indicators. An extensive review of past and recent literature reveals that mammography is not an objective examination. Its use as a screening tool is facilitated among women 40 years old and older whose breast tissue is primarily fatty and provides better visualization. Younger women are not generally advised to use mammography because of its potentially hazardous effects associated with repeated use of radiation. More importantly, regardless of patient age, radiologists interpret mammograms, and different degrees of interpretation error exist for different radiologists as well as for the same radiologist performing the analysis after a period of time. Thus, the use of mammography as the sole screening tool does not provide patients or physicians with a sense of confidence about sensitivity and specificity. Further, recent enthusiasm to promote mammography screening may give women unrealistic expectations, leading them to falsely believe that a negative examination is assurance that cancer is not present in its earliest detectable stage. We propose to supplement the physical examination and mammography with a third screening modality based on thermal detection monitors. This is a noninvasive and nonradiogenic tool and might enable clinicians to provide patients with every opportunity for early diagnosis.","PeriodicalId":80044,"journal":{"name":"Journal of women's health & gender-based medicine","volume":"1 1","pages":"17-25"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90320193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 15

News from the Society for Women's Health Research: subgroup analysis in clinical trials: detecting sex differences. 来自妇女健康研究协会的消息:临床试验中的亚组分析:检测性别差异。

Journal of women's health & gender-based medicine Pub Date : 2002-01-01 DOI: 10.1089/152460902753473390

P. Greenberger, S. Knab

引用次数: 1

Possible beneficial effect of exercise, by reducing oxidative stress, on the incidence of preeclampsia. 通过减少氧化应激，运动可能对子痫前期的发病率有有益的影响。

Journal of women's health & gender-based medicine Pub Date : 2001-12-01 DOI: 10.1089/152460901317193558

SeonAe Yeo, S. Davidge

{"title":"Possible beneficial effect of exercise, by reducing oxidative stress, on the incidence of preeclampsia.","authors":"SeonAe Yeo, S. Davidge","doi":"10.1089/152460901317193558","DOIUrl":"https://doi.org/10.1089/152460901317193558","url":null,"abstract":"We hypothesize that regular exercise enhances antioxidative enzymes in pregnant women, which reduce oxidative stress and, thus, the incidence of preeclampsia. Oxidative stress with enhanced lipid peroxide formation could lead to endothelial dysfunction in preeclampsia. Other conditions, such as increased transferrin saturation and decreased iron-binding capacity, directly and indirectly promote the process of oxidative stress and subsequent endothelial dysfunction. Exercise increases oxidative metabolism and produces a prooxidant environment. This acidic environment during exercise (at or beyond anaerobic threshold) promotes oxygen release from hemoglobin and increases in PO(2) in tissues, as well as releases iron from transferrin. When exercise is repeated regularly, the body promptly adjusts so that oxidative stress is eliminated or reduced. The body's adaptations to a regular exercise habit seem to have an antioxidant effect. In humans, training effects have been identified with an enhanced activity of antioxidative enzymes. Another concerted adaptation that regular exercise brings to women's bodies is resistance against production of prooxidants by increasing the number of mitochondria. Equally important is a training effect that decreases susceptibility to lipid peroxidation. Evidence suggests that physically active women are less likely to develop preeclampsia. In theory, intracellular and extracellular conditions resulting from regular exercise should counteract the enhancement of oxidative stress, thus interfering with the process leading to endothelial dysfunction. This position paper describes a hypothesis and includes a brief review of exercise physiology and biochemical research in preeclampsia. Unlike other preventive treatments, such as aspirin or calcium supplements, a regular exercise habit leads to a positive and healthy lifestyle without concern of side effects.","PeriodicalId":80044,"journal":{"name":"Journal of women's health & gender-based medicine","volume":"36 1","pages":"983-9"},"PeriodicalIF":0.0,"publicationDate":"2001-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74026758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 47

An open trial of mirtazapine in menopausal women with depression unresponsive to estrogen replacement therapy. 米氮平对雌激素替代疗法无反应的绝经期抑郁症妇女的公开试验。

Journal of women's health & gender-based medicine Pub Date : 2001-12-01 DOI: 10.1089/152460901317193576

H. Joffe, Heather Groninger, C. Soares, R. Nonacs, L. Cohen

{"title":"An open trial of mirtazapine in menopausal women with depression unresponsive to estrogen replacement therapy.","authors":"H. Joffe, Heather Groninger, C. Soares, R. Nonacs, L. Cohen","doi":"10.1089/152460901317193576","DOIUrl":"https://doi.org/10.1089/152460901317193576","url":null,"abstract":"Treatment of major depression in menopausal women is controversial. Estrogen replacement therapy (ERT) treats mild depression but may not treat more severe depression in this population. Antidepressants are recommended as treatment for major depression in menopausal women, but the specific efficacy of antidepressants has not been examined in menopause-associated depression. Twenty-two perimenopausal and postmenopausal women aged 40-61 taking stable doses of ERT who met Structured Clinical Interview for DSM-IV (SCID-IV) criteria for major depression were accessioned into an open-label clinical trial of mirtazapine. Subjects were treated with 30-45 mg/day mirtazapine for 8 weeks and were assessed every 2 weeks with the Hamilton Depression Rating Scale-17 (HDRS-17), Beck Depression Inventory (BDI), and Clinical Global Impression (CGI) Scale. Remission of depression was defined as an HDRS-17 score < or =7 at the week 8 study visit. Sixteen (73%) of the enrolled subjects completed the 8-week study. The median HDRS-17 score declined from 20.5 (range 12-37) at baseline to 2 (range 0-9) at week 8 (Wilcoxon signed-rank test, p < 0.001). Remission of depression was achieved by 14 of 16 (87.5%) study completers. Subjects responded well to mirtazapine regardless of whether their depression preceded ERT use or developed after ERT was initiated. Therapeutic response also appeared independent of menopausal status (perimenopausal vs. postmenopausal), ERT preparation, and concomitant use of medroxyprogesterone. Mirtazapine is an effective treatment for major depression in perimenopausal and postmenopausal women whose depression precedes ERT use and does not respond to ERT or whose depression develops after ERT is initiated.","PeriodicalId":80044,"journal":{"name":"Journal of women's health & gender-based medicine","volume":"27 1","pages":"999-1004"},"PeriodicalIF":0.0,"publicationDate":"2001-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91195749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 57

Identifying and caring for underserved populations: experience of the National Centers of Excellence in Women's Health. 确定和照顾服务不足的人口:国家妇女健康卓越中心的经验。

Journal of women's health & gender-based medicine Pub Date : 2001-12-01 DOI: 10.1089/152460901317193521

T. Weitz, K. Freund, L. Wright

{"title":"Identifying and caring for underserved populations: experience of the National Centers of Excellence in Women's Health.","authors":"T. Weitz, K. Freund, L. Wright","doi":"10.1089/152460901317193521","DOIUrl":"https://doi.org/10.1089/152460901317193521","url":null,"abstract":"From 1996 through 1998, 18 National Centers of Excellence in Women's Health (CoEs) were designated by the Office on Women's Health (OWH) of the U.S. Department of Health and Human Services (DHHS). These CoEs were charged with developing standards for comprehensive, multidisciplinary, and culturally competent approaches to women's health. One specific mandate to the CoEs was to address the needs of underserved women. This paper presents the efforts of the CoE Racial and Ethnic Minority and Underserved Women Working Group to describe the work done within the CoEs to meet this mandate. One method of defining underserved populations is the seven-point definition used in the current \"Index for Primary Care Shortage,\" which categorizes underserved populations based on characteristics including race, ethnicity, geography, and health outcomes. The definition allows the local identification of underserved communities based on this group of variables. The analysis included in this paper focuses specifically on the CoEs' efforts to operationalize this definition in order to meet the clinical care needs of women who are of low socioeconomic status (SES), racial or ethnic minorities, or non-English speaking. A brief review of the literature linking these characteristics to being underserved is provided, followed by examples of ongoing activities at the 15 currently funded CoEs, to understand the needs of diverse women, to improve the quality of care provided to women, and to address healthcare needs of underserved women who meet this definition. Efforts to serve three additional underserved populations defined by age, sexual orientation, and disability status are also presented.","PeriodicalId":80044,"journal":{"name":"Journal of women's health & gender-based medicine","volume":"63 3 1","pages":"937-52"},"PeriodicalIF":0.0,"publicationDate":"2001-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82458884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 22

Observations from the CDC. Community Prevention Study: contributions to women's health and prevention research. 来自疾病预防控制中心的观察。社区预防研究:对妇女健康和预防研究的贡献。

Journal of women's health & gender-based medicine Pub Date : 2001-12-01 DOI: 10.1089/152460901317193495

B. Ainsworth, L. Anderson, D. Becker, S. Blalock, D. Brown, R. Brownson, N. Brownstein, C. Cornell, B. Devellis, L. Finnegan, S. Folger, J. Fulton, J. Groff, C. Herman, D. Jones, T. Keyserling, D. M. Matson Koffman, C. Lewis, L. Mâsse, R. Mckeown, D. Orenstein, A. J. Spadaro

引用次数: 7

Training programs for healthcare professionals in domestic violence. 为医疗保健专业人员提供家庭暴力方面的培训方案。

Journal of women's health & gender-based medicine Pub Date : 2001-12-01 DOI: 10.1089/152460901317193530

L. Davidson, J. Grisso, C. Garcia-Moreno, J. Garcia, V. King, S. Marchant

引用次数: 71