Annals of Movement Disorders最新文献_第4页

Botulinum toxin injections during the COVID-19 epidemic: A retrospective chart review COVID-19流行期间肉毒杆菌毒素注射:回顾性图表回顾

Annals of Movement Disorders Pub Date : 2023-01-01 DOI: 10.4103/aomd.aomd_30_22

Saurabh Nandwani, Anumeha Mishra, Ganeshgouda Majigoudra, S. Pandey

{"title":"Botulinum toxin injections during the COVID-19 epidemic: A retrospective chart review","authors":"Saurabh Nandwani, Anumeha Mishra, Ganeshgouda Majigoudra, S. Pandey","doi":"10.4103/aomd.aomd_30_22","DOIUrl":"https://doi.org/10.4103/aomd.aomd_30_22","url":null,"abstract":"BACKGROUND AND AIM: Clinical services were severely affected globally during the COVID-19 pandemic. This study aimed to characterize the clinical experience of using botulinum toxin (BTX) injections during the COVID-19 pandemic. METHODS: This is a retrospective chart review of patients who received BTX injections from April 2019 to January 2022. RESULTS: A total of 105 patients received an BTX injections, out of which 76 (72.4%) were men. The mean age of the patients was 47.9 ± 15.1 years. The most common indication for receiving BTX injections was dystonia (n = 79; 75.2%), followed by hemifacial spasm (n = 22; 21%) and miscellaneous movement disorders (n = 4; 3.8%). Focal dystonia (n = 45; 57%) was the most frequent form of dystonia, followed by segmental dystonia (n = 24; 30%). The percentage of generalized dystonia and hemidystonia was 12% and 1%, respectively. Cervical dystonia (44.4%), blepharospasm (17.8%), and writer’s cramp (15.6%) were the most frequent forms of focal dystonia. The miscellaneous group included four patients (3.8%) with trigeminal neuralgia, Holmes tremor, dystonic tics, and hemimasticatory spasm. The mean ages of patients in the dystonia, hemifacial spasm, and the miscellaneous groups were 47.7 ± 14.9 years, 49.2 ± 14.0 years, and 44.2 ± 26.0 years, respectively. The mean BTX dose was 131.6 ± 104.1 U. The mean BTX doses for the dystonia group, hemifacial spasm, and the miscellaneous group were 158.7 ± 105.3 U, 40.1 ± 11.3 U, and 100.0 ± 70.7 U, respectively. CONCLUSION: Most patients in our cohort had dystonia, followed by hemifacial spasm. Among the patients with dystonia, most had focal dystonia, with cervical dystonia being the most common movement disorder. The data obtained in our study is important to increase awareness of the effectiveness of BTX injections in patients with chronic disorders.","PeriodicalId":7973,"journal":{"name":"Annals of Movement Disorders","volume":"6 1","pages":"13 - 16"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45948585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Can parkinsonian gait be a predictor of unresponsiveness to CSF tap test in normal-pressure hydrocephalus? 帕金森步态是否可作为常压脑积水患者脑脊液抽头试验无反应的预测指标?

Annals of Movement Disorders Pub Date : 2023-01-01 DOI: 10.4103/aomd.aomd_8_22

H. Onder

引用次数: 0

Stem cell therapy for spinocerebellar ataxias: A narrative review 干细胞治疗脊髓小脑共济失调:一个叙述性的回顾

Annals of Movement Disorders Pub Date : 2023-01-01 DOI: 10.4103/aomd.aomd_48_22

R. Singh, M. Bhartiya, Ayush Agarwal, Divya Radhakrishnan, R. Rajan, A. Srivastava

引用次数: 0

Paraneoplastic cerebellar degeneration heralding recurrent metastatic carcinoma breast 副肿瘤小脑变性预示着乳腺癌复发性转移癌

Annals of Movement Disorders Pub Date : 2023-01-01 DOI: 10.4103/aomd.aomd_5_22

Rambhupal Nagireddy, Amit Kumar, D. Joshi

引用次数: 0

Huffing and puffing sign in functional axial jerks with secondary gait impairment 功能性轴性急动伴继发性步态障碍的哈芬顿和喘胀征

Annals of Movement Disorders Pub Date : 2023-01-01 DOI: 10.4103/aomd.aomd_16_22

K. Patel, Asish Vijayaraghavan, Syam Krishnan, D. Puthenveedu

引用次数: 0

Automated analysis of pen-on-paper spirals for tremor detection, quantification, and differentiation 自动分析笔在纸上的螺旋震颤检测，量化，和分化

Annals of Movement Disorders Pub Date : 2023-01-01 DOI: 10.4103/aomd.aomd_50_22

R. Rajan, R. Anandapadmanabhan, S. Nageswaran, V. Radhakrishnan, Arti Saini, Syam Krishnan, Anuragini Gupta, V. Vishnu, A. Pandit, Rajesh Kumar Singh, Divya Radhakrishnan, Mamta Bhushan Singh, R. Bhatia, A. Srivastava, A. Kishore, M. Padma Srivastava

{"title":"Automated analysis of pen-on-paper spirals for tremor detection, quantification, and differentiation","authors":"R. Rajan, R. Anandapadmanabhan, S. Nageswaran, V. Radhakrishnan, Arti Saini, Syam Krishnan, Anuragini Gupta, V. Vishnu, A. Pandit, Rajesh Kumar Singh, Divya Radhakrishnan, Mamta Bhushan Singh, R. Bhatia, A. Srivastava, A. Kishore, M. Padma Srivastava","doi":"10.4103/aomd.aomd_50_22","DOIUrl":"https://doi.org/10.4103/aomd.aomd_50_22","url":null,"abstract":"Objective: To develop an automated algorithm to detect, quantify, and differentiate between tremor using pen-on-paper spirals. Methods: Patients with essential tremor (n = 25), dystonic tremor (n = 25), Parkinson’s disease (n = 25), and healthy volunteers (HV, n = 25) drew free-hand spirals. The algorithm derived the mean deviation (MD) and tremor variability from scanned images. MD and tremor variability were compared with 1) the Bain and Findley scale, 2) the Fahn–Tolosa–Marin tremor rating scale (FTM–TRS), and 3) the peak power and total power of the accelerometer spectra. Inter and intra loop widths were computed to differentiate between the tremor. Results: MD was higher in the tremor group (48.9 ± 26.3) than in HV (26.4 ± 5.3; p < 0.001). The cut-off value of 30.3 had 80.9% sensitivity and 76.0% specificity for the detection of the tremor [area under the curve: 0.83; 95% confidence index (CI): 0.75, 0.91, p < 0.001]. MD correlated with the Bain and Findley ratings (rho = 0.491, p = 0 < 0.001), FTM–TRS part B (rho = 0.260, p = 0.032) and accelerometric measures of postural tremor (total power, rho = 0.366, p < 0.001; peak power, rho = 0.402, p < 0.001). Minimum Detectable Change was 19.9%. Inter loop width distinguished Parkinson’s disease spirals from dystonic tremor (p < 0.001, 95% CI: 54.6, 211.1), essential tremor (p = 0.003, 95% CI: 28.5, 184.9), or HV (p = 0.036, 95% CI: -160.4, -3.9). Conclusion: The automated analysis of pen-on-paper spirals generated robust variables to quantify the tremor and putative variables to distinguish them from each other. Significance: This technique maybe useful for epidemiological surveys and follow-up studies on tremor.","PeriodicalId":7973,"journal":{"name":"Annals of Movement Disorders","volume":"6 1","pages":"17 - 25"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42601555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Geste antagoniste in dystonia: Demystifying the tricks 肌张力障碍中的手势对抗：破解技巧

Annals of Movement Disorders Pub Date : 2023-01-01 DOI: 10.4103/aomd.aomd_51_22

S. Prasad, V. Holla, Lulup Kumar Sahoo, Dhruv Batra, Albert Stezin, R. Mahale, N. Kamble, R. Yadav, P. Pal

引用次数: 0

A juvenile-onset case of autosomal recessive spastic ataxia of charlevoix–saguenay with a novel mutation in the SACS gene 一例青少年发病的常染色体隐性遗传性沙葛痉挛性共济失调SACS基因新突变病例

Annals of Movement Disorders Pub Date : 2023-01-01 DOI: 10.4103/aomd.aomd_15_22

H. Onder, V. Topçu, S. Comoglu

引用次数: 0

Escitalopram-induced rabbit syndrome 艾司西酞普兰诱发兔综合征

Annals of Movement Disorders Pub Date : 2023-01-01 DOI: 10.4103/aomd.aomd_21_22

Nitish Batra, Prerna Verma, Neha Phate, Sunil Kumar

引用次数: 0

Myoclonus associated with infections: A narrative review 与感染相关的肌阵挛:叙述性回顾

Annals of Movement Disorders Pub Date : 2022-09-01 DOI: 10.4103/AOMD.AOMD_25_22

A. Kothiala, V. Shankar, S. Desai

{"title":"Myoclonus associated with infections: A narrative review","authors":"A. Kothiala, V. Shankar, S. Desai","doi":"10.4103/AOMD.AOMD_25_22","DOIUrl":"https://doi.org/10.4103/AOMD.AOMD_25_22","url":null,"abstract":"Different movement disorders are reported in association with infectious diseases. In addition, myoclonus can be associated with different types of viral and bacterial infections. We screened three electronic databases for cases of myoclonus as a feature of different infections and collected cases and series describing myoclonus associated with infections. Data regarding study design, sample size, neurological assessment, and diagnostic workup including brain imaging and cerebrospinal fluid analysis were extracted from the identified studies. In this narrative review, we review different infections associated with myoclonus and discuss their salient features. The infections presenting with myoclonus include predominantly subacute sclerosing panencephalitis due to measles. In addition, we describe other viral infections that are reported to associated with myoclonus. Recently, coronavirus disease 2019 infections have been reported to be increasingly associated with myoclonus. The hypothesized mechanisms of infection-related myoclonus are vasculopathy, autoimmune reactions, and inflammation. Although myoclonus is considered to be a result of heredodegenerative, metabolic, or autoimmune disorders, infections may present with myoclonus, especially in tropical and developing countries. In this review, we describe the infections that are associated with myoclonus.","PeriodicalId":7973,"journal":{"name":"Annals of Movement Disorders","volume":"5 1","pages":"137 - 152"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43069134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0