Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology最新文献_第6页

[The clinical application of compound induced hypotension during functional endoscopic sinus surgery]. 【复合诱导降压在功能性内镜鼻窦手术中的临床应用】。

Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology Pub Date : 2006-12-01

Tao Wu, Jun Yang, Kai Luo, Yingwei Wang, Xinmin You

{"title":"[The clinical application of compound induced hypotension during functional endoscopic sinus surgery].","authors":"Tao Wu, Jun Yang, Kai Luo, Yingwei Wang, Xinmin You","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To assess the clinic efficacy of compound induced hypotension during functional endoscopic sinus surgery.Method: Sixty patients with chronic sinusitis and nasal polyps were divided into three groups: Sodium nitroprusside (SNP) group (A), diltiazem+SNP group (B), labetalol+SNP group (C). We started induced hypotension with beginning of functional endoscopic sinus surgery. Mean arterial pressure (MAP), heart rate (HR), cardiac output (CO), cardiac index (CI) and ejection fraction (EF) were recorded during induced hypotension. Sugar and lactic acid in arterial and venous blood were also assayed. Then we calculate rate-pressure product (RPP), arteriovenous difference in blood glucose [D(v-a) BG], blood glucose extraction rate (BGER), arteriovenous difference in lactate [L(v-a)] and lactate produce rate (LPR).Result: The dose of SNP applied in group B and C are fewer than group A ( P <0. 05). The cardiovascular functions and body metabolism of the patients in group B and C were stable and the anesthetic effect was satisfactory. Few adverse reaction of the drug was found in present study.Conclusion: Induced hypotension with SNP compound of diltiazem or labetalol is an ideal way in clinical use and produce satisfied synergistic effect.","PeriodicalId":79680,"journal":{"name":"Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology","volume":"20 24","pages":"1126-9"},"PeriodicalIF":0.0,"publicationDate":"2006-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26602303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Operation of chronic sphenoid sinusitis with endoscopic sinus surgery]. 慢性蝶窦炎的内窥镜手术治疗

Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology Pub Date : 2006-12-01

Jun Li, Xia Zhang, Haifang Tang, Yuqing Bai

引用次数: 0

[Determination and the diversity characteristic of the cytokine levels in the supernatants of spleen cell cultures of experimental allergic rhinitis mice]. [实验性变应性鼻炎小鼠脾细胞培养上清中细胞因子水平的测定及多样性特征]。

Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology Pub Date : 2006-12-01

Yue Zhou, Jianjun Chen, Weijia Kong

{"title":"[Determination and the diversity characteristic of the cytokine levels in the supernatants of spleen cell cultures of experimental allergic rhinitis mice].","authors":"Yue Zhou, Jianjun Chen, Weijia Kong","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To investigate the cytokine level in the supernatants of spleen cell stimulated with different stimulus of allergic rhinitis model at different time, compared the effect of the two stimulus to the cytokine, and its secrete status.Method: We sensitized and challenged the BALB/c mice with ovalbumin (OVA), in the control group normal sodium instead of OVA was used. After the last challenge we cultured the spleen mononuclear cell (SMNC) and stimulated with OVA or concanavalin A (ConA), then got the supernatants of the SMNC cultures at 24 h, 48 h and 72 h respectively to measure the concentration of cytokine IL-4, IL-5 and IFN-gamma.Result: Production of IL-4, IL-5 and IFN-gamma by ConA-stimulated SMNC from sensitized mice increased significantly (P < 0.05); the concentration of IL-4 and IL-5 by OVA-stimulated SMNC from sensitized mice also increased, inversely the production of IFN-gamma resulted suppression. The level of IL-4 was increased obviously in 72 hours, IL-5 and IFN-gamma were increased significantly in 48 hours, and slow down from 48 to 72 hours.Conclusion: The T cells of the experimental allergic rhinitis mice were generally activated. Production of cytokines from Th2 cells by OVA or ConA increased significantly, but Th1 cells and its cytokines were suppressed. The result was more obvious in the ConA-stimulated group. The levels of cytokines increased persistently within 72 hours.","PeriodicalId":79680,"journal":{"name":"Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology","volume":"20 23","pages":"1088-91"},"PeriodicalIF":0.0,"publicationDate":"2006-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26596641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[The diagnosis and treatment of cerebrospinal rhinorrhea caused by transsphenoidal cephalocele through transnasal endoscopic surgery]. 【经鼻内镜手术治疗经蝶窦性头膨出所致脑脊液鼻漏的诊断与治疗】。

Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology Pub Date : 2006-12-01

Haili Lü, Qiuhang Zhang, Bo Yan, Zhili Ni, Haisheng Liu

引用次数: 0

[The effect of TNF-alpha & IL-8 in the pathogenesis of allergic rhinitis]. [tnf - α和IL-8在变应性鼻炎发病中的作用]。

Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology Pub Date : 2006-12-01

Zhongxi Wang

引用次数: 0

[Expression and clinical significance of survivin gene and PTEN gene in laryngeal squamous cell carcinomas]. [survivin基因和PTEN基因在喉鳞癌中的表达及临床意义]。

Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology Pub Date : 2006-12-01

Li Zhu, Shuyi Wang

{"title":"[Expression and clinical significance of survivin gene and PTEN gene in laryngeal squamous cell carcinomas].","authors":"Li Zhu, Shuyi Wang","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To investigate the expression and clinical significance of anti-apoptosis gene Survivin and tumor suppressor gene PTEN in laryngeal squamous cell carcinomas (LSCC) METHOD: The expression of Survivin and PTEN protein were detected by immunohistochemistry Envision method in 71 specimens of LSCC, and 10 specimens of vocal cord polyp as control.Result: No Survivin was detected in polyp of vocal cord. However, it was detected in 53 of 71 (74. 6%) specimens from the patients with LSCC. The Survivin expression was unrelated to the age and sex of patients or the size of tumors ( P >0.05) ,but related to the tumor site, clinical stage, histological grade, lymphatic metastasis and tumor prognosis ( P <0. 05). PTEN had the expression in all specimens of vocal cord polyp. However, it was detected in 33 of 71 (46. 5%) specimens of laryngeal carcinoma. The PTEN expression was unrelated to the clinical data including age, gender, tumor size and site ( P >0. 05), but related to the clinical stage, pathological grade, lymph node metastasis and prognosis ( P <0. 05). There was a negative correlation between Survivin expression and PTEN expression ( P <0. 05).Conclusion: The abnormal expression of Survivin and PTEN gene may be related to carcinogenesis, tumor progress and prognosis. The Survivin and PTEN gene may act as markers predicting biological behavior of LSCC. The coexpression of Survivin and PTEN gene have the synergism in carcinogenesis and tumor progress of LSCC.","PeriodicalId":79680,"journal":{"name":"Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology","volume":"20 24","pages":"1113-5"},"PeriodicalIF":0.0,"publicationDate":"2006-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26602299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[The use of Mandarin hearing in noise test in non-Mandarin speakers]. [普通话听力在非普通话人群噪音测试中的应用]。

Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology Pub Date : 2006-12-01

Sha Liu, Demin Han, Na Han, Bo Liu, Xueqing Chen, Liansheng Guo, Hui Liu, Dan Zhang, Ning Zhang

引用次数: 0

[Study on the expression of angiogenesis and spontaneous apoptosis and their relevance in laryngeal squamous cell carcinoma]. [喉鳞癌血管生成和自发凋亡的表达及其相关性研究]。

Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology Pub Date : 2006-12-01

Haizhou Zheng, Shan Lin, Shenqing Wang, Libo Dai

{"title":"[Study on the expression of angiogenesis and spontaneous apoptosis and their relevance in laryngeal squamous cell carcinoma].","authors":"Haizhou Zheng, Shan Lin, Shenqing Wang, Libo Dai","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To investigate the relationship among angiogenesis, spontaneous apoptosis and clinicopathological parameters in laryngeal squamous cell carcinoma (LSCC).Method: The intratumor microvessel density (IMVD), apoptotic index (AI) and vascular endothelial growth factor (VEGF) expression were detected by immunohistochemistry SABC and terminal uridine deoxynucleotidyl transferase mediated nick end labeling(TUNEL) methods in 34 LSCC patients.Result: The average IMVD was (21.50 +/- 8.87), and median of AI was 1.15%. The average IMVD in positive and negative cervical lymphatic metastasis was (26.33 +/- 9.70) and (17.68 +/- 6.06) respectively, and the IMVD with positive lymphatic metastasis tumors was statistical significantly higher than those with negative cervical lymphatic metastasis tumors (P < 0.01). The average IMVD had statistical difference in histological grading (P < 0.01), and analysis by one to one, the average IMVD had statistical difference between high and median grading. Expression of VEGF had a significantly positive correlation with IMVD (r = 0.51, P < 0.01). Statistical analysis revealed a significantly inverse correlation between AI and IMVD (r = -0.53, P < 0.01). We failed to find the statistical difference between IMVD and tumor T-stage in LSCC.Conclusion: IMVD may be an important indicator to predict cervical lymphatic metastasis in LSCC. VEGF might be an important angiogenic factor, and could promote tumor angiogenesis in LSCC. Tumor angiogenesis might contribute to tumor malignant progression by inhibiting spontaneous apoptosis in LSCC.","PeriodicalId":79680,"journal":{"name":"Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology","volume":"20 23","pages":"1082-4"},"PeriodicalIF":0.0,"publicationDate":"2006-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26596639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Endoscopic transnasal surgery for anterior skull base lesions]. 内镜下经鼻手术治疗前颅底病变。

Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology Pub Date : 2006-12-01

Rongping Cao, Hao Wu, Qi Huang, Youjin Li, Zhaoyan Wang

引用次数: 0

[A clinic study on treatment of chronic frontal sinusitis with endoscopic surgery and permanent implantation of a place holder]. [内镜手术联合永久植入位架治疗慢性额窦炎的临床研究]。

Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology Pub Date : 2006-12-01

Zhishen Li, Guohua Shi, Shilong Zhang

{"title":"[A clinic study on treatment of chronic frontal sinusitis with endoscopic surgery and permanent implantation of a place holder].","authors":"Zhishen Li, Guohua Shi, Shilong Zhang","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To investigate the characteristics of chronic frontal sinusitis and to improve the clinical therapeutic efficacy.Method: Sixty-eight patients (130 sides) who underwent endoscopic frontal sinus surgery in our department were randomly divided into three groups: Group 1 included 23 patients (43 operations) underwent endonasal sinus surgery with the frontal sinus opened and drained by two pipes of silicone for 6 months. Group 2 included 24 patients (45 operations) treated as group 1 but added injection of beclomethasone (approximately 1 cc, 94 mcg/100 microliters). Group 3 included 21 patients (42 operations) with only frontal sinus opened.Result: After an average follow-up of 18 months, the cure rate in group 1, group 2 and group 3 was 93%, 93% and 71% respectively.Conclusion: The ultimate success or failure of frontal sinus surgical procedures, whether they are endonasal or external, depends on the restenosis of the frontal sinus outflow tract or neo-ostium postoperatively. Long-term stenting for a period of several months will significantly reduce the possibility of restenosis. We recommend that this type of management be considered in difficult revision cases and before performing an external operation.","PeriodicalId":79680,"journal":{"name":"Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology","volume":"20 23","pages":"1065-8"},"PeriodicalIF":0.0,"publicationDate":"2006-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26596247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0