Annals of palliative medicine最新文献

{"title":"Metastasis-directed therapy in oligoprogressive prostate cancer: current evidence and future directions.","authors":"Jarey H Wang, Daniel Huang, Emmanuel Jnr Amoateng, Asha Tipirneni, Hong Zhang, Kevin Bylund, Michael Cummings, Phuoc T Tran, Matthew P Deek, Philip A Sutera","doi":"10.21037/apm-2026-0041","DOIUrl":"10.21037/apm-2026-0041","url":null,"abstract":"<p><p>Oligoprogression in prostate cancer is increasingly recognized as a clinically meaningful state with increased incidence due to effective systemic therapies and more sensitive molecular imaging, particularly prostate-specific membrane antigen positron emission tomography (PET). Broadly, oligoprogressive prostate cancer is defined as progression at a limited number of metastatic sites, commonly three to five or fewer, while the remainder of disease remains stable on ongoing therapy. In prostate cancer, however, this concept spans biologically and clinically distinct states, including repeat oligorecurrence off systemic therapy, new oligometastasis at the time of castration-resistance, and oligoprogression in castration-resistant disease. These differences are important because the goals of metastasis-directed therapy (MDT) differ across settings. In castration-sensitive disease, local therapy is often used to delay initiation or re-initiation of androgen deprivation therapy (ADT) and preserve quality of life. In castration-resistant disease, the goal is more often to ablate resistant clones, prolong the benefit of otherwise effective systemic therapy, and defer next-line treatment. Prospective randomized phase II data in oligometastatic castration-sensitive prostate cancer (CSPC) support MDT as an ADT-sparing strategy, and emerging studies suggest that repeat courses of stereotactic body radiotherapy (SBRT) may remain feasible in selected patients with serial limited-site recurrence. In metastatic castration-resistant prostate cancer (mCRPC), two randomized phase II trials and multiple prospective and retrospective series support the addition of MDT in carefully selected men. Across both disease states, local control rates are high and grade 3 or higher toxicity is uncommon. Nevertheless, major questions remain regarding optimal patient selection, imaging definitions, integration with systemic intensification, and the role of biomarkers in distinguishing durable oligoprogression from impending polyprogression. This review summarizes the biologic rationale, clinical evidence, and future directions for MDT in oligoprogressive prostate cancer.</p>","PeriodicalId":7956,"journal":{"name":"Annals of palliative medicine","volume":"15 4","pages":"64"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148705176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A systematic review of psychotherapy for persons receiving palliative and hospice care, their caregivers, and patient-caregiver dyads.","authors":"David A Deemer, Allison J Applebaum, Joo-Young Lee, Nicholas Safian, Gabrielle E Milner, Mikayla G Wexler, Gloria Willson, Shahla Baharlou","doi":"10.21037/apm-2026-0025","DOIUrl":"https://doi.org/10.21037/apm-2026-0025","url":null,"abstract":"<p><strong>Background: </strong>Patients receiving palliative or hospice care and their caregivers frequently experience depression, anxiety, hopelessness, and fear of death. While previous reviews sought to clarify the impact of psychotherapy interventions for individuals receiving palliative and hospice care, none focused on the impact of psychotherapeutic interventions delivered by mental health professionals with formal psychotherapy training to all populations impacted. The aim of the present study was to systematically review the literature evaluating the efficacy of various psychotherapeutic interventions administered by mental health professionals, delivered to patients, their caregivers, and patient-caregiver dyads targeting a diverse set of outcomes.</p><p><strong>Methods: </strong>We conducted a systematic review of the literature to examine specific forms of psychotherapy support delivered by mental health professionals with formal psychotherapy training, assessed by validated quantitative instruments, offered to patients receiving palliative or hospice care, their caregivers, and patient-caregiver dyads. Risk of bias was assessed by either the Cochrane risk of bias assessment for randomized-controlled trials (RCTs), or the Newcastle-Ottawa Quality Assessment Form for Cohort studies for pilot/feasibility studies.</p><p><strong>Results: </strong>Twenty-seven studies met the criteria for inclusion in our final review after title/abstract and full-text screening. A wide variety of psychotherapeutic modalities and clinical outcomes were captured. Existential-phenomenological and life review/memory specificity therapy had the strongest current evidence base. Studies of cognitive behavioral therapy and dignity therapy (DT) almost uniformly found no significance in outcomes.</p><p><strong>Conclusions: </strong>While often well-tolerated and appreciated, psychotherapy administered by mental health professionals with formal psychotherapy training inconsistently improves objective outcomes for patients receiving palliative care, their caregivers, and patient-caregiver dyads-a demographic uniquely impacted by advanced disease states and subsequent existential distress. Studies that utilized mixed-effect model intention-to-treat analyses to account for loss to follow-up and blinding approaches like delayed intervention for control groups were rated as high quality.</p>","PeriodicalId":7956,"journal":{"name":"Annals of palliative medicine","volume":"15 4","pages":"58"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148705080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of stereotactic body radiotherapy (SBRT) for metastatic cancer patients beyond the traditional oligometastatic setting: a narrative review for an evolving concept.","authors":"Raquel Ciervide, Mercedes López, Ovidio Hernando, Ángel Montero, Rafael García","doi":"10.21037/apm-2026-0030","DOIUrl":"https://doi.org/10.21037/apm-2026-0030","url":null,"abstract":"<p><strong>Background and objective: </strong>The management of metastatic cancer is shifting from a strict division between curative local therapy and palliative systemic treatment toward a biology-driven continuum. In this setting, stereotactic body radiotherapy (SBRT), or stereotactic ablative radiotherapy (SABR), has emerged as an effective consolidative approach for patients with limited metastatic burden. Its role is now being explored beyond the classical oligometastatic paradigm, including oligoprogressive and selected polymetastatic disease. This narrative review summarizes the evidence supporting SBRT/SABR in patients with metastatic burden exceeding the traditional definition (≤3-5 metastases), focusing on emerging clinical scenarios.</p><p><strong>Methods: </strong>A structured PubMed/MEDLINE search identified studies published between January 2000 and December 2025 using MeSH and free-text terms related to stereotactic radiotherapy and metastatic disease states. Randomized trials, prospective cohorts, and retrospective studies evaluating SBRT/SABR in oligoprogressive and other non-classical settings were included. Reviews, case reports, and preclinical studies were excluded. Due to heterogeneity in definitions and study designs, findings were synthesized narratively.</p><p><strong>Key content and findings: </strong>Prospective and observational data show that SBRT/SABR achieves high local control with acceptable toxicity in oligometastatic disease and is increasingly investigated in patients with higher metastatic burden. The conventional cutoff of ≤3-5 metastases appears arbitrary, with ongoing trials assessing broader indications. Clinical benefit is strongly influenced by tumor biology, with more favorable outcomes in prostate and renal cell carcinoma than in other malignancies. SBRT/SABR is also used in oligoprogressive disease to prolong systemic therapy efficacy and for local symptom control. Patient-reported outcomes suggest disease progression, rather than treatment toxicity, is the main driver of quality-of-life decline.</p><p><strong>Conclusions: </strong>SBRT/SABR may extend beyond the oligometastatic paradigm, but lesion count alone is insufficient for patient selection. Optimal use requires individualized, biology-driven strategies. Future research should refine selection criteria, incorporate biomarkers, and clarify integration with systemic therapies.</p>","PeriodicalId":7956,"journal":{"name":"Annals of palliative medicine","volume":"15 4","pages":"61"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148705128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypnosis and bleeding disorders: a narrative review-with a focus on hemophilia.","authors":"Jessie Porzi, Amandine Berner, Matteo Coen","doi":"10.21037/apm-2026-1-0021","DOIUrl":"https://doi.org/10.21037/apm-2026-1-0021","url":null,"abstract":"<p><strong>Background and objective: </strong>Hypnosis has been explored for its therapeutic effects in bleeding disorders since the 1960s, yet this relationship remains inadequately characterized in contemporary medical literature. This study aimed to provide a narrative review examining the relationship between hypnosis and bleeding disorders, with emphasis on hemophilia, and identify evidence gaps.</p><p><strong>Methods: </strong>A literature search was conducted using PubMed (1946-October 2025) with keywords \"Hypno*\" AND \"Bleed*\" without restrictions on article origin, language, or study design.</p><p><strong>Key content and findings: </strong>Of 527 articles identified, 37 were retained, predominantly case reports and small trials. Twenty-five articles (68%) focused on hemophilia. Four randomized controlled trials were identified (total n=90). Publications concentrated in 1960-1980 (40.5%), with declining frequency thereafter. Evidence on bleeding reduction is mixed: historical studies suggested reduced bleeding frequency and factor use, while recent trials showed non-significant trends. Contemporary research focuses on quality of life, with hypnosis demonstrating significant improvements in pain interference with daily activities and health-related quality of life, despite not reducing absolute pain intensity. Effects persisted at three-month follow-up. Hypnosis showed good feasibility and safety, with 90-100% retention rates and no adverse events. Additional evidence supports hypnotic interventions in surgical bleeding, menstrual disorders, gastrointestinal hemorrhage, epistaxis, and hematuria.</p><p><strong>Conclusions: </strong>Hypnosis demonstrates promise as an adjunctive intervention in bleeding disorders, particularly for improving quality of life in people with hemophilia. Contemporary protocols focus on relaxation and anxiety reduction rather than direct bleeding control, reflecting understanding of stress-mediated effects on hemostasis. Future adequately powered trials should elucidate mechanisms and identify patient populations most likely to benefit. Given consistent evidence for improved health-related quality of life and safety, hypnosis warrants consideration as a component of comprehensive care for bleeding disorders.</p>","PeriodicalId":7956,"journal":{"name":"Annals of palliative medicine","volume":"15 4","pages":"63"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148705138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Palliative care involvement in solid organ transplant: a narrative review.","authors":"Zaheera Lukman, Maisha T Robinson, Molly M Kilpatrick","doi":"10.21037/apm-2026-1-0024","DOIUrl":"10.21037/apm-2026-1-0024","url":null,"abstract":"<p><strong>Background and objective: </strong>Solid organ transplant has increased within the last 50 years, particularly as surgical procedures, transplant outcomes, brain death criteria, and immunosuppressive therapies are improving. While transplant programs have specific criteria to help identify ideal transplant candidates, some programs are recognizing the emotional and physical burden that transplant candidates have leading up to the transplant decision; as such, a multidisciplinary approach to candidate evaluation which involves social work, psychiatry, nursing, and other disciplines is necessary for transplant success. Due to the complex nature of medical illnesses that lead to solid organ transplant, and the significant impact on quality of life, palliative care involvement both pre-transplant and post-transplant has been identified as a helpful support for patients. This narrative review summarizes relevant literature on the involvement of palliative care in transplant and provides a conversation guide for supporting patients through the transplant process from a palliative lens.</p><p><strong>Methods: </strong>Authors ran a narrative review search in the National Library of Medicine (NLM) PubMed database. The search was restricted to English language articles, and publication date filters limited the results from January 1, 2015 to the day the search was run on April 2, 2026. An effort was made to exclude animal studies. Search terms included Medical Subject Headings (MeSH) terms as well as keywords, including terms for palliative care, palliative medicine, transplantation, solid organ transplant, conversation guide, heart transplant, liver transplant, lung transplant, kidney transplant, attitudes, perspectives, trajectory, utilization, outpatient, inpatient, early palliative care, referral, cost-savings, and their synonyms.</p><p><strong>Key content and findings: </strong>While palliative care involvement in transplantation has been well studied, only certain transplant groups, particularly heart and liver, have formally updated guidelines to reflect this. Palliative care providers should continue to partner with transplant teams in order to better support patients and caregivers throughout all stages of end-stage disease, particularly pre- and post-transplant.</p><p><strong>Conclusions: </strong>Further consideration should be given to healthcare outcomes with palliative team involvement in transplant populations. More research is needed to determine optimal timing, setting, and resource availability of palliative teams.</p>","PeriodicalId":7956,"journal":{"name":"Annals of palliative medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148547715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The evolving role and impact of patient navigators in serious illness care: a narrative review.","authors":"Jennifer A Wylie, Crystal Diaz, Audry S Sebikali-Potts, Fabian M Johnston","doi":"10.21037/apm-2025-1-140","DOIUrl":"10.21037/apm-2025-1-140","url":null,"abstract":"<p><strong>Background and objective: </strong>In today's increasingly complex and fragmented healthcare system, patient navigation has emerged as a strategy to improve access to palliative care and reduce health inequities among historically marginalized populations. This narrative review aims to examine the evolution of patient navigation and its implementation across care settings to identify key themes and opportunities to optimize outcomes and reduce disparities in patients with serious illnesses.</p><p><strong>Methods: </strong>A literature search was conducted in PubMed, Cumulative Index of Nursing and Allied Health Literature (CINAHL) Ultimate, and Google Scholar by three independent investigators on articles related to patient navigation in palliative care and patients with serious illnesses. A total of 49 academic articles and 5 additional articles were included.</p><p><strong>Key content and findings: </strong>A review of the literature revealed a number of diverse models of care navigation and implementation strategies. Navigation models involved varying degrees of community-based personnel and healthcare professionals from a range of disciplines. Through culturally informed support, education, and empowerment, many of these programs demonstrated improved patient outcomes such as reduced symptom burden, increased advance care planning, improved hospice referrals, more goal-concordant care at the end of life, reduced end-of-life cost expenditure, hospitalizations and emergency room visits. Integration of navigation across both medical and community settings also helped to reduce health disparities by addressing barriers across multiple levels of influence. However, in order for such models to be successful, understanding and integration of cultural values, trusted community figures, and strategies for addressing language barriers are essential.</p><p><strong>Conclusions: </strong>While a variety of approaches to patient navigation can help improve care for seriously ill patients, common themes of effective interventions include social connection, engagement in what is most meaningful to the patient, identification of patient needs, access to culturally grounded resources, patient advocacy and empowerment, incorporation of navigators embedded within the local community, and support from key stakeholders.</p>","PeriodicalId":7956,"journal":{"name":"Annals of palliative medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147979823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Palliative care for patients with haematologic malignancies: challenges and opportunities.","authors":"Joanne Droney, Jennifer Vidrine","doi":"10.21037/apm-2026-1-0014","DOIUrl":"https://doi.org/10.21037/apm-2026-1-0014","url":null,"abstract":"","PeriodicalId":7956,"journal":{"name":"Annals of palliative medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147979804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Code status among surgical patients at a rural teaching hospital.","authors":"Lauren McKay, Alexis Kohlbeck, Melissa Scribani, Jennifer Victory, Nicole Krupa, Ana Berlin, Joon K Shim","doi":"10.21037/apm-2025-1-143","DOIUrl":"10.21037/apm-2025-1-143","url":null,"abstract":"<p><strong>Background: </strong>Code status is infrequently addressed in surgical disciplines unless there is a specific triggering event. Consistency and quality of code status discussions at a rural teaching hospital were evaluated, focusing on surgical residents' performance.</p><p><strong>Methods: </strong>Study was conducted at Bassett Medical Center in Cooperstown, New York, a rural teaching, tertiary hospital. Bassett Healthcare Network has affiliations with Columbia University. A retrospective analysis of emergency department (ED) to inpatient surgical admissions from 1/1/2022 to 12/31/2023 was conducted of surgical patients (n=716) 18 years or older, excluding trauma, multiple admissions, and patients without a surgical procedure. Patient age, sex, race, insurance status, American Society of Anesthesiologists (ASA) class, discharge disposition, procedure, and service team requesting the procedure were collected. Code status orders were reviewed to assess whether Medical Orders for Life-Sustaining Treatment (MOLST) were on file, code status was discussed by the admitting clinician, and a new or revised MOLST was completed.</p><p><strong>Results: </strong>About 94% of patients were documented as having no MOLST form, nor explicit discussion of code status resulting in completion of a MOLST form. 24.44% of patients had advance care planning documents in their electronic health record. 91.43% of these patients also had \"NO\" to all three MOLST questions in their admission orders. Majority of patients were ASA class 3 (60%) and most common surgeries were laparotomy (11.31%), laparoscopic cholecystectomy (11.17%), laparoscopic appendectomy (6.56%), and esophagogastroduodenoscopy (3.77%).</p><p><strong>Conclusions: </strong>Discussing code status with surgical patients is critical to providing complete surgical care, yet our results add to evidence of inconsistency in doing so. Rural areas face additional challenges, such as resource scarcity and older, comorbid populations. To bridge these gaps in surgical care, there is necessity for additional programming, such as rural surgical training programs, to ensure appropriate, informed, and patient-centered code status management for every surgical patient, regardless of geography.</p>","PeriodicalId":7956,"journal":{"name":"Annals of palliative medicine","volume":"15 3","pages":"35"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148215607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case series of patients with head and neck cancer undergoing curative-intent chemoradiation receiving low dose transdermal buprenorphine for pain.","authors":"Kevin Dyer, Mara Feingold-Link, Dana Guyer","doi":"10.21037/apm-2026-1-0008","DOIUrl":"10.21037/apm-2026-1-0008","url":null,"abstract":"<p><strong>Background: </strong>Buprenorphine is a semisynthetic partial µ-opioid receptor agonist used for opioid use disorder and increasingly for cancer-related pain. Transdermal buprenorphine (TDB) is effective for both nociceptive and neuropathic pain and may be particularly advantageous in patients with head and neck cancer (HNC) due to its pharmacologic profile and non-oral route of administration. Existing literature evaluates the efficacy of high dose TDB (>30 µg/h) in symptom management and demonstrates equivocal effectiveness to morphine. In the United States, TDB patches are only available in 5, 7.5, 10, 15, and 20 µg/h patches with a max dose of 20 µg/h approved by the Food and Drug Administration. Data on low-dose TDB for HNC-related pain and treatment-associated toxicities, including mucositis, are limited.</p><p><strong>Case description: </strong>We performed a single center, retrospective review of nine patients with HNC who started or completed treatment between 2024 to 2025 All patients were treated in the HNC multidisciplinary clinic, which includes medical oncology, radiation oncology, otolaryngology, nutrition, navigation, and a palliative care physician at an academic hospital. Pain was treated primarily with TDB at varying doses, with adjuvant analgesics as needed, and patients were followed longitudinally during the course of their treatment. Analgesic regimens were adjusted as anticipated complications such as mucositis and odynophagia developed. While some patients required short-term full agonist opioids, most required fewer than 30 oral morphine equivalents daily in addition to their TDB. All patients were successfully weaned off full agonist opioids during post-treatment follow-up. Most patients completed their treatments with minimal interruptions. Instances of incomplete treatment included extenuating social circumstances, chemotherapy-related acute kidney injury, and dose-limiting cytopenias.</p><p><strong>Conclusions: </strong>In our clinical experience, low dose TDB demonstrated efficacy in managing pain and limiting the need for full agonist opioids, and patients were able to achieve complete weaning of all full agonist opioids post-treatment. This study shows that low dose TDB can be a viable analgesic option for pain related to HNC and treatment sequelae while reducing total exposure to full agonist opioids, which makes it an ideal choice for patients who may have a history of substance use disorder.</p>","PeriodicalId":7956,"journal":{"name":"Annals of palliative medicine","volume":"15 3","pages":"41"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148216072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"(Electronic) patient reported outcomes: an undervalued tool for discussions on palliative care?","authors":"Eva Oldenburger, Johan Menten","doi":"10.21037/apm-2026-1-0005","DOIUrl":"https://doi.org/10.21037/apm-2026-1-0005","url":null,"abstract":"","PeriodicalId":7956,"journal":{"name":"Annals of palliative medicine","volume":"15 3","pages":"32"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148216053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}