Journal of transplant coordination : official publication of the North American Transplant Coordinators Organization (NATCO)最新文献_第8页

New Strategies Using ‘Low-Dose’ Mycophenolate Mofetil to Reduce Acute Rejection in Patients following Kidney Transplantation 使用“低剂量”霉酚酸酯减少肾移植后患者急性排斥反应的新策略

Journal of transplant coordination : official publication of the North American Transplant Coordinators Organization (NATCO) Pub Date : 1999-06-01 DOI: 10.1177/090591999900900209

P. Ulsh, Harold C. Yang, M. Holman, N. Ahsan

引用次数: 0

Azathioprine Monotherapy in HLA-Identical Live Donor Kidney Transplant Recipients 硫唑嘌呤单药治疗hla相同活体肾移植受者

Journal of transplant coordination : official publication of the North American Transplant Coordinators Organization (NATCO) Pub Date : 1999-03-01 DOI: 10.1177/090591999900900105

M. Bartucci, S. Fleming-Brooks, B. Koshla, T. Knauss, D. Hricik, J. Schulak

{"title":"Azathioprine Monotherapy in HLA-Identical Live Donor Kidney Transplant Recipients","authors":"M. Bartucci, S. Fleming-Brooks, B. Koshla, T. Knauss, D. Hricik, J. Schulak","doi":"10.1177/090591999900900105","DOIUrl":"https://doi.org/10.1177/090591999900900105","url":null,"abstract":"Journal of Transplant Coordination, Vol. 9, Number 1, March 1999 of hypertension,13-15 reduction in serum lipid levels,16-19 correction of posttransplant diabetes mellitus,19 and accelerated growth in children.20,21 Reported benefits of CsA withdrawal have included reduced cost and avoidance of long-term nephrotoxicity.10,11 Hypertension occurs in more than 50% of renal transplant recipients and has been attributed to multiple factors, including the presence of diseased native kidneys, acute and chronic allograft rejection, recurrence of original disease, and transplant renal artery stenosis. Although corticosteroids are known to elevate blood pressure in nontransplant patients, the role of these agents in the pathogenesis of posttransplant hypertension remains controversial. The influence of steroids has been further obscured by the routine use of CsA that also exacerbates posttransplant hypertension. However, studies have shown that cessation of steroids is accompanied by a significant decrease in mean arterial blood pressure and by a reduction in the number of required antihypertensive medications.6 , 7 , 1 2 1 5 Multivariate analysis in one study in which patients were maintained on AZA and CsA after steroid withdrawal showed the reduction in blood pressure was directly related to the prior severity of hypertension and inversely related to the dose of CsA.13 Hypercholesterolemia is common after renal transAzathioprine monotherapy in HLA-identical live donor kidney transplant recipients","PeriodicalId":79507,"journal":{"name":"Journal of transplant coordination : official publication of the North American Transplant Coordinators Organization (NATCO)","volume":"52 1","pages":"35 - 39"},"PeriodicalIF":0.0,"publicationDate":"1999-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/090591999900900105","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65464924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Willingness to donate organs and tissues in Vietnam. 在越南捐献器官和组织的意愿。

Journal of transplant coordination : official publication of the North American Transplant Coordinators Organization (NATCO) Pub Date : 1999-03-01

T B Hai, T Eastlund, L A Chien, P T Duc, T H Giang, N T Hoa, P H Viet, D Q Trung

{"title":"Willingness to donate organs and tissues in Vietnam.","authors":"T B Hai, T Eastlund, L A Chien, P T Duc, T H Giang, N T Hoa, P H Viet, D Q Trung","doi":"","DOIUrl":"","url":null,"abstract":"Context: Few studies on public attitudes toward organ and tissue donation have been carried out in Asia.Objective: To determine demographic influences on attitudes toward organ and tissue donation in Vietnam.Design: Face-to-face interviews.Setting: Tan Binh District, Ho Chi Minh City, Vietnam.Participants: Random sample of adults (N = 785).Main outcome measures: Awareness of donation and transplantation, acceptance of organ and tissue donation.Results: 75% of respondents stated they had heard of organ or tissue donation, but only 55% were aware of organ and tissue transplantation taking place in Vietnam. Forty-eight percent of Buddhists and 27.5% of Christians had either no knowledge or incorrect knowledge about their religion's official position toward donation and transplantation. Sixty-four percent stated they would give consent for the donation of their decreased relative's tissues and organs, 66% would themselves become posthumous donors, and 21% to 22% would donate multiple organs and tissues. A significant association was found between respondents' acceptance of organ and tissue donation and their educational level, sex, occupation, and awareness of transplantation. Most respondents stated that their willingness to donate depended on whether other family members agreed. Many noted the importance of preventing commerce in organ and tissue transplantation but were in favor of providing healthcare for the donor's family or monetary incentives as a reward for donating.Conclusion: Nearly two thirds of urban Vietnamese surveyed were willing to donate organs or tissues after death. Their willingness was related to awareness of transplantation, sex, education level, and occupation.","PeriodicalId":79507,"journal":{"name":"Journal of transplant coordination : official publication of the North American Transplant Coordinators Organization (NATCO)","volume":"9 1","pages":"57-63"},"PeriodicalIF":0.0,"publicationDate":"1999-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21268927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Program Development and Routine Notification in a Large, Independent OPO: A 12-Year Review 大型独立OPO的项目开发和例行通知:12年回顾

Journal of transplant coordination : official publication of the North American Transplant Coordinators Organization (NATCO) Pub Date : 1999-03-01 DOI: 10.1177/090591999900900106

T. Shafer, C. V. van Buren, Charles A. Andrews

{"title":"Program Development and Routine Notification in a Large, Independent OPO: A 12-Year Review","authors":"T. Shafer, C. V. van Buren, Charles A. Andrews","doi":"10.1177/090591999900900106","DOIUrl":"https://doi.org/10.1177/090591999900900106","url":null,"abstract":"Review of the Literature Shafer et al21 reported some of the first OPO benchmarking data available to the industry on what might result from successful organ recovery in defined geographic service areas. Evans1 reported that the potential for organ donation in the United States ranges from 27.6 to 42.8 donors per million population (pmp); according to Gortmaker et al,23 the potential ranges from 27.6 to 42.8 donors pmp. Nathan et al24 found that the potential donor pool in Pennsylvania in 1987 ranged from 38.3 to 55.2 donors pmp. Although OPOs have steadily applied numerous resources and countless hours in an attempt to maximize this potential, donation rates in the United States have stalled around 21 donors pmp, with OPOs in the upper quartile of production achieving greater than 24 donors pmp.25 The growth of organ recovery is stagnated for many reasons. Two of the reasons—lack of donor identification and lack of consent by families of the Program development and routine notification in a large, independent OPO: a 12-year review","PeriodicalId":79507,"journal":{"name":"Journal of transplant coordination : official publication of the North American Transplant Coordinators Organization (NATCO)","volume":"9 1","pages":"40 - 49"},"PeriodicalIF":0.0,"publicationDate":"1999-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/090591999900900106","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65465264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Azathioprine monotherapy in HLA-identical live donor kidney transplant recipients. 硫唑嘌呤单药治疗hla相同活体肾移植受者。

Journal of transplant coordination : official publication of the North American Transplant Coordinators Organization (NATCO) Pub Date : 1999-03-01 DOI: 10.7182/prtr.1.9.1.v52h0082041k1751

M R Bartucci, S Flemming-Brooks, B Koshla, T C Knauss, D E Hricik, J A Schulak

{"title":"Azathioprine monotherapy in HLA-identical live donor kidney transplant recipients.","authors":"M R Bartucci, S Flemming-Brooks, B Koshla, T C Knauss, D E Hricik, J A Schulak","doi":"10.7182/prtr.1.9.1.v52h0082041k1751","DOIUrl":"https://doi.org/10.7182/prtr.1.9.1.v52h0082041k1751","url":null,"abstract":"The high success rate of HLA-identical sibling transplants and our previous experience with steroid-free immunosuppressive regimens and cyclosporine withdrawal prompted us to evaluate the safety and efficacy of monotherapy with azathioprine in 12 HLA-identical kidney transplant recipients with a serum creatinine concentration less than 176.8 mumol/L, a 1-way stimulatory index less than 2.0 in a post-transplant mixed lymphocyte culture, and a demonstrated tolerance of a minimum azathioprine dose of 1.0 mg/kg per day without leukopenia. Eleven of 12 patients were successfully converted to azathioprine monotherapy without a significant change in serum creatinine concentration for as long as 76 months. Benefits of steroid and cyclosporine withdrawal included a significant reduction in mean systolic and diastolic blood pressure, number of blood pressure medications, total serum cholesterol, and glycohemoglobin in diabetic subjects. Our results suggest that azathioprine monotherapy is safe and effective in a select group of HLA-identical sibling transplants, but these benefits must be carefully balanced against an associated risk of precipitating acute allograft rejection.","PeriodicalId":79507,"journal":{"name":"Journal of transplant coordination : official publication of the North American Transplant Coordinators Organization (NATCO)","volume":"9 1","pages":"35-9"},"PeriodicalIF":0.0,"publicationDate":"1999-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21268438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

The Use of Over-the-Counter Medications by Transplant Recipients: A Guideline 移植受者使用非处方药:指南

Journal of transplant coordination : official publication of the North American Transplant Coordinators Organization (NATCO) Pub Date : 1999-03-01 DOI: 10.1177/090591999900900103

T. Ellingson, D. Wipke-Tevis, C. Messina, T. Livesay

引用次数: 0

Promoting Adherence to Transplant Medication Regimens: A Review of Behavioral Analysis 促进移植药物治疗方案的依从性:行为分析综述

Journal of transplant coordination : official publication of the North American Transplant Coordinators Organization (NATCO) Pub Date : 1999-03-01 DOI: 10.1177/090591999900900102

S. Newton

{"title":"Promoting Adherence to Transplant Medication Regimens: A Review of Behavioral Analysis","authors":"S. Newton","doi":"10.1177/090591999900900102","DOIUrl":"https://doi.org/10.1177/090591999900900102","url":null,"abstract":"Journal of Transplant Coordination, Vol. 9, Number 1, March 1999 administering the medications. However, studies have shown that at least one third of patients do not adhere to their drug regimens.3,4,5 Conrad4 suggests that compliance rates with medication regimens over long periods tend to approach 50%. It has also been shown that multiple medications and/or multiple doses per day of a medication—a common pattern for transplant recipients—tend to have higher rates of nonadherence.6 For transplant recipients, not adhering to the immunosuppressant regimen can result in rejection, graft loss, and even death.3 It has been documented that transplanted allografts are needlessly lost, due to recipient nonadherent behaviors.7 In one study,3 a third of liver transplant recipients were nonadherent with their immunosuppressant medication regimen. Perhaps the most surprising finding is that nonadherent behaviors generally occur when early posttransplant complications have been surpassed and long-term engraftment seems to have been achieved.7 According to some researchers, medication nonadherence causes more graft loss than does uncontrollable rejection in compliant recipients.3","PeriodicalId":79507,"journal":{"name":"Journal of transplant coordination : official publication of the North American Transplant Coordinators Organization (NATCO)","volume":"167 1","pages":"13 - 16"},"PeriodicalIF":0.0,"publicationDate":"1999-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/090591999900900102","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65464971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Discriminant Variables between Organ Donors and Nondonors: A Post Hoc Investigation 器官供者和非供者之间的判别变量:一项事后调查

Journal of transplant coordination : official publication of the North American Transplant Coordinators Organization (NATCO) Pub Date : 1999-03-01 DOI: 10.1177/090591999900900107

J. Rosel, M. Frutos, M. Blanca, P. Ruiz

引用次数: 0

The use of over-the-counter medications by transplant recipients: a guideline. 移植受者使用非处方药:指南。

Journal of transplant coordination : official publication of the North American Transplant Coordinators Organization (NATCO) Pub Date : 1999-03-01 DOI: 10.7182/prtr.1.9.1.487821t0k2015512

T Ellingson, D Wipke-Tevis, C Messina, T Livesay

引用次数: 7

Dealing with the fear of mutilation in the donation discussion. 在捐赠讨论中处理对残割的恐惧。

Journal of transplant coordination : official publication of the North American Transplant Coordinators Organization (NATCO) Pub Date : 1999-03-01 DOI: 10.7182/prtr.1.9.1.ng3r6718543619g4

M Verble, J Worth

引用次数: 19