New Strategies Using ‘Low-Dose’ Mycophenolate Mofetil to Reduce Acute Rejection in Patients following Kidney Transplantation

Abstract

Journal of Transplant Coordination, Vol. 9, Number 2, June 1999 cyclosporine-based regimens, episodes of acute rejection exceed 50% in some centers. Several authors have demonstrated that the frequency and severity of these acute rejections significantly shorten the overall halflife of renal allografts.2,3 With this observation, many of the recent studies have used the number and severity of acute rejections as primary efficacy end point. New strategies using ‘low-dose’ mycophenolate mofetil to reduce acute rejection in patients following kidney transplantation