Seminars in reproductive endocrinology最新文献_第9页

Psychobiology of premenstrual dysphoric disorder. 经前焦虑症的心理生物学。

Seminars in reproductive endocrinology Pub Date : 1997-02-01 DOI: 10.1055/s-2008-1067968

B L Parry

引用次数: 27

Anxiety disorders in women: gender-related modulation of neurobiology and behavior. 女性焦虑症:神经生物学和行为的性别相关调节。

Seminars in reproductive endocrinology Pub Date : 1997-02-01 DOI: 10.1055/s-2008-1067969

M K Shear

引用次数: 27

Psychobiology of postpartum mood disorders. 产后情绪障碍的心理生物学。

Seminars in reproductive endocrinology Pub Date : 1997-02-01 DOI: 10.1055/s-2008-1067970

K L Wisner, Z N Stowe

引用次数: 100

The perimenopause and affective disorders. 围绝经期和情感性障碍。

Seminars in reproductive endocrinology Pub Date : 1997-02-01 DOI: 10.1055/s-2008-1067971

P J Schmidt, C A Roca, M Bloch, D R Rubinow

引用次数: 72

Behaviorally induced reproductive compromise in women and men. 行为诱导的男女生殖妥协。

Seminars in reproductive endocrinology Pub Date : 1997-02-01 DOI: 10.1055/s-2008-1067967

S L Berga

引用次数: 20

Integrins and other cell adhesion molecules in endometrium and endometriosis. 子宫内膜和子宫内膜异位症中的整合素和其他细胞粘附分子。

Seminars in reproductive endocrinology Pub Date : 1997-01-01 DOI: 10.1055/s-2008-1068759

B A Lessey, S L Young

{"title":"Integrins and other cell adhesion molecules in endometrium and endometriosis.","authors":"B A Lessey, S L Young","doi":"10.1055/s-2008-1068759","DOIUrl":"https://doi.org/10.1055/s-2008-1068759","url":null,"abstract":"Endometriosis is a disease that affects about 5% of women of reproductive age, but is found much more frequently in those with pelvic pain and/or infertility. In affected individuals, shed endometrium is thought to attach and spread within the pelvis through specific cell adhesion receptors. To understand why some women develop endometriosis while others do not, researchers have begun to examine these receptors and their extracellular matrix ligands. Cell adhesion molecules fall into 4 major groups including cadherins, selectins, members of the immunoglobulin superfamily, and integrins. Based on our current understanding, each may potentially play a role in the development or progression of this disease. In addition, the use of integrins as markers of the normal endometrial phenotype may be useful for the diagnosis of endometriosis and may identify women with defects in endometrial function leading to infertility or recurrent pregnancy loss. As more information becomes available, it may be possible to develop better treatments for endometriosis based on these concepts and to identify those women at risk for development of this common yet serious disorder.","PeriodicalId":79457,"journal":{"name":"Seminars in reproductive endocrinology","volume":"15 3","pages":"291-9"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-2008-1068759","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20313993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 66

Diagnosis of endometriosis. 诊断子宫内膜异位症。

Seminars in reproductive endocrinology Pub Date : 1997-01-01 DOI: 10.1055/s-2008-1068752

I Brosens

引用次数: 104

Role of endothelial cells in the steroidogenic activity of the bovine corpus luteum. 内皮细胞在牛黄体类固醇生成活性中的作用。

Seminars in reproductive endocrinology Pub Date : 1997-01-01 DOI: 10.1055/s-2008-1068375

R Meidan, E Girsh

引用次数: 12

Is there a genetic basis to endometriosis? 子宫内膜异位症有遗传基础吗?

Seminars in reproductive endocrinology Pub Date : 1997-01-01 DOI: 10.1055/s-2008-1068761

S Kennedy

引用次数: 47

The role of GnRH agonists plus add-back therapy in the treatment of endometriosis. GnRH激动剂加加回疗法在子宫内膜异位症治疗中的作用。

Seminars in reproductive endocrinology Pub Date : 1997-01-01 DOI: 10.1055/s-2008-1068757

A R Gargiulo, M D Hornstein

{"title":"The role of GnRH agonists plus add-back therapy in the treatment of endometriosis.","authors":"A R Gargiulo, M D Hornstein","doi":"10.1055/s-2008-1068757","DOIUrl":"https://doi.org/10.1055/s-2008-1068757","url":null,"abstract":"Agonistic analogs of GnRH have emerged as effective drugs in the treatment of pelvic pain associated with endometriosis. Iatrogenic hypoestrogenism is the fundamental mechanism through which GnRH agonists induce regression of the exquisitely estrogen-dependent endometriotic lesions. The decrease in bone mass consistently observed in women on long-term GnRH agonist treatment has prompted regulatory agencies such as the FDA to approve the use of these drugs for a maximum of six months in the treatment of endometriosis. The very high recurrence rate of pelvic symptomatology after the interruption of medical therapy underlines the importance of strategies aiming at improving the safety of effective long-term treatments. Data has recently become available suggesting the existence of an ideal range of circulating estradiol levels which would maintain a normal bone metabolism and still cause atrophy of endometriotic lesions. Add-back regimens including estrogen preparations have been therefore studied with variable results. In strict analogy, as oral progestins have been shown to improve bone mass in postmenopausal women, regimens employing progestin add-back have been proposed. Our review describes most of the currently published studies employing these and other substances in association with the commonly used GnRH agonists in patients with symptomatic endometriosis.","PeriodicalId":79457,"journal":{"name":"Seminars in reproductive endocrinology","volume":"15 3","pages":"273-84"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-2008-1068757","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20314044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11