Pathology (Philadelphia, Pa.)最新文献

{"title":"Immunopathology of malignant mesothelioma.","authors":"K Sheibani,&nbsp;R M Stroup","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The pathologic diagnosis of malignant mesothelioma is difficult because the disease is rare and because it has many morphologic variants. This chapter emphasizes practical aspects of the pathologic features and of the differential diagnosis of malignant mesothelioma.</p>","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"4 1","pages":"191-212"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19916924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuroendocrine tumors of the lung.","authors":"A M Marchevsky","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The lung can develop a spectrum of neuroendocrine neoplasms, whose histopathologic classification is difficult, controversial, and potentially confusing for the surgical pathologist. This chapter describes the various pulmonary endocrine tumors of the lung and provides guidelines for their differential diagnosis.</p>","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"4 1","pages":"103-23"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19916919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Low-grade B-cell lymphomas of lung and lymphomatoid granulomatosis.","authors":"M Koss,&nbsp;E H Zeren","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The last decade has seen major advances in our knowledge of the clinical and biologic behavior of lymphomas of lung. These advances have in turn led to intriguing hypotheses that attempt to explain the origin of these lesions. In this chapter, the authors summarize the background and evolution of these intriguing lymphomas.</p>","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"4 1","pages":"125-39"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19916920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fine-needle aspiration diagnosis of HIV-related conditions.","authors":"D Hanks,&nbsp;V Bhargava","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors highlight the more common conditions that can be diagnosed by FNA, offering examples to illustrate how material obtained from FNA can be triaged for effective patient management. They also discuss the HIV-related changes found in body fluids and other cytologic specimens, such as those from bronchoalveolar lavage and induced sputum.</p>","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"4 2","pages":"221-52"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20182047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intraoperative consultation: introduction and general principles.","authors":"M Ranchod","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"3 2","pages":"259-71"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19766517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lung.","authors":"C M Lombard","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"3 2","pages":"321-38"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19766522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Soft tissue.","authors":"R L Kempson","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"3 2","pages":"545-53"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19767848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vasculitis of the lung.","authors":"W D Travis,&nbsp;M V Fleming","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Many conditions are known to produce vasculitis of the lung but only a few major idiopathic vasculitis syndromes are clinically encountered-- and their diagnosis is very difficult. The authors provide in-depth coverage of these syndromes, focusing on clinical features, pathologic features, and diagnosis and differential diagnosis.</p>","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"4 1","pages":"23-41"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19916916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fine-needle aspiration cytology of the thyroid.","authors":"P B Jeffrey,&nbsp;T R Miller","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Fine-needle aspiration of the thyroid, in experienced hands, is an extremely specific and sensitive tool. The authors provide an in-depth discussion of FNA for both benign and malignant lesions of the thyroid, and they offer a flow chart with diagnostic indicators that also clarifies areas of overlap between lesions.</p>","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"4 2","pages":"319-35"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20182050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fine-needle aspiration of the head and neck.","authors":"L J Layfield","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Fine-needle aspiration cytology is a valuable technique in the work-up of nodules and masses arising within the head and neck. Squamous cell carcinoma is present most often, and because of this relative frequency, the primary utility of needle-aspiration cytology is in the confirmation or exclusion of this diagnosis. FNA is particularly helpful in the work-up of cervical masses and nodules because biopsy of cervical adenopathy should be avoided unless all other diagnostic modalities have failed to establish a diagnosis. As such, needle-aspiration cytology represents an accurate, inexpensive, and rapid technique for elucidation of the etiology of cervical adenopathy. The majority of aspirates from cervical lymph nodes will disclose either reactive lymphadenopathy or metastatic squamous cell carcinoma. Occasional nodules will be due to lymphoma. While primary diagnosis of lymphoma by needle-aspiration cytology is generally not considered definitive, it is helpful in clarifying the nature of the process and the direction additional diagnostic tests should take. Similarly, establishing the presence of carotid body tumors, brachial cleft cysts or epidermal inclusion cysts excludes metastatic carcinoma and negates the need for open biopsy as well as allaying concerns on the part of both clinician and patient. Fine-needle aspiration of lesions within the mouth, oral pharynx, nasopharynx, and nasal sinuses has similar diagnostic goals, in that eliminating squamous cell carcinoma is its paramount objective. Fine-needle aspiration cytology can also establish a specific diagnosis for many lesions within this area. This technique can make specific diagnoses of angiofibroma, primary adenocarcinoma of the nasal sinuses, rhabdomyoma, granular cell tumor, and rhabdomyosarcoma. Each of these represents an important clinical entity with a specific therapy. Utilizing electron microscopy and immunohistochemical techniques, along with flow cytometry, can greatly broaden the diagnostic range and specificity of needle-aspiration cytology. Flow cytometry and immunohistochemistry are particularly useful in the establishment of monoclonality in lymphoproliferative processes and, hence, aid in the separation of reactive from lymphomatous lymphadenopathy. Immunohistochemistry can establish the precise nature of lesions as variable as rhabdomyosarcoma, olfactory neuroblastoma, and granular cell tumor. The prudent use of these techniques can be cost-effective and negate the need for more invasive diagnostic procedures. Needle-aspiration cytology represents a cost-effective and rapid technique for the assessment of nodules and masses within the head and neck area. Limitations in accuracy exist. In particular, the separation of reactive atypia in benign squamous epithelium from well-differentiated squamous cell carcinoma may be exceedingly difficult, if not impossible. Nonetheless, the technique has a high degree of accuracy for the diagnosis of both primary and metastati","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"4 2","pages":"409-38"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20183275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}