{"title":"The number needed to be treated as a valuable parameter in interpreting clinical trial findings.","authors":"B Bannwarth","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79371,"journal":{"name":"Revue du rhumatisme (English ed.)","volume":"66 6","pages":"361-2"},"PeriodicalIF":0.0,"publicationDate":"1999-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21285432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Young age at onset, renal involvement, and arterial hypertension are of adverse prognostic significance in juvenile systemic lupus erythematosus.","authors":"R Marini, L T Costallat","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To look for associations between mortality, clinical or laboratory data, and age at disease onset in systemic lupus erythematosus patients aged 16 years or younger at disease onset.</p><p><strong>Patients and methods: </strong>The medical records of patients seen at the Clinics Hospital, State University of Campinas, São Paulo, Brazil, between 1979 and 1995 were reviewed retrospectively. All 59 included patients (48F/11M) fulfilled four or more American College of Rheumatology criteria for systemic lupus erythematosus. Patients with discold, drug-induced or neonatal lupus, or other systemic connective tissue diseases were excluded. Patients were studied individually then classified in three groups based on age at disease onset, as follows: Group I, < or = 9 years of age; Group II, 10-14 years of age; and Group III, 15-16 years of age. Clinical and laboratory abnormalities and mortality were compared in the three groups.</p><p><strong>Results: </strong>The most frequent clinical manifestations were joint symptoms (91.5%), renal involvement (71.1%), malar rash (61%), alopecia (61%), fever (59.3%) and photosensitivity (52.5%). Laboratory findings included antinuclear antibody in 94.9% of cases. LE cells in 71.1%, low serum complement in 65.3%, anti-DNA in 63.4%, hematuria in 62.7%, and proteinuria in 61%. The mortality rate was 23.7% (9F/5M) overall, 18.7% in females, and 45.4% in males (P = 0.07). The cause of death was infection in eight patients (57.1% of decedents), central nervous system disease in five (35.7%), and renal insufficiency in one (7.2%). Disease onset before 15 years of age (P = 0.026), renal involvement (P = 0.03), and arterial hypertension (P = 0.002) were predictive of mortality. Mortality was not influenced by gender or race.</p>","PeriodicalId":79371,"journal":{"name":"Revue du rhumatisme (English ed.)","volume":"66 6","pages":"303-9"},"PeriodicalIF":0.0,"publicationDate":"1999-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21284193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sporadic ulcerative-mutilating acropathy of the foot. Features and therapeutic indications.","authors":"L de Palma, S Carloni, S Rapali, A Ventura","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Ulcerative-mutilating acropathy occurs as an inherited (Thévenard's disease) and a sporadic (Bureau-Barrière syndrome) variant. We report a retrospective study in nine patients with the sporadic variant. All nine had painless foot ulcers with trophic disorders and severe skeletal alterations. Electrodiagnostic testing showed polyneuropathy with sensory disorders in seven patients. Motor conduction velocity was normal. Radiological changes were confined to the lower limbs. The clinical course and treatment of sporadic ulcerative-mutilating acropathy are presented.</p>","PeriodicalId":79371,"journal":{"name":"Revue du rhumatisme (English ed.)","volume":"66 6","pages":"319-22"},"PeriodicalIF":0.0,"publicationDate":"1999-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21284196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L Le Gars, J M Savy, P Orcel, F Liote, D Kuntz, J M Tubiana, G Kaplan, J D Laredo
{"title":"Osteonecrosis-like syndrome of the medial tibial plateau can be due to a stress fracture. MR findings in 13 patients.","authors":"L Le Gars, J M Savy, P Orcel, F Liote, D Kuntz, J M Tubiana, G Kaplan, J D Laredo","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To demonstrate the contribution of magnetic resonance imaging to the elucidation of mechanisms involved in \"osteonecrosis-like syndrome of the medial tibial plateau\".</p><p><strong>Patients and methods: </strong>A magnetic resonance study with sagittal and coronal sections was done in 13 patients (age range, 57-95 years) two weeks to four months into a painful syndrome meeting the definition of \"osteonecrosis-like syndrome of the medial tibial plateau\". Gadolinium injection was used in nine patients. Clinical symptoms resolved within a few weeks in all 13 cases.</p><p><strong>Results: </strong>T1-weighted images without gadolinium showed diffuse low signal from the epiphysis (n = 12) containing an area of even lower signal seen either as a crescent-shaped subchondral image (n = 3/12) or as a linear image (n = 9/12). On postgadolinium images, the low signal was abolished except for a line of low signal parallel to the subchondral bone. T2-weighted images demonstrated diffuse high signal from the medial tibial plateau with persistence of the line of low signal (n = 8/12).</p><p><strong>Conclusion: </strong>Magnetic resonance imaging allows to analyze the anatomic lesion responsible for \"osteonecrosis-like syndrome of the medial tibial plateau\". Our magnetic resonance findings were similar to those seen in stress fractures at other sites.</p>","PeriodicalId":79371,"journal":{"name":"Revue du rhumatisme (English ed.)","volume":"66 6","pages":"323-30"},"PeriodicalIF":0.0,"publicationDate":"1999-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21284197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R Niamane, N Birouk, A Benomar, M Benabdejlil, A Amarti, M Yahyaoui, T Chkili, N Hajjaj-Hassouni
{"title":"Rigid spine syndrome. Two case-reports.","authors":"R Niamane, N Birouk, A Benomar, M Benabdejlil, A Amarti, M Yahyaoui, T Chkili, N Hajjaj-Hassouni","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Unlabelled: </strong>Rigid spine syndrome is characterized by massive spinal rigidity, usually most marked in the cervical region. Stiffness of the peripheral joints is sometimes present. We report two cases. Patient 1 was a 12-year-old boy diagnosed at three years of age with Duchenne's muscular dystrophy because of delayed onset of walking. Contracture of the Achilles tendons, flexion contracture of the elbows, and loss of motion of the cervical spine were the main findings during the current evaluation. Radiographs of the affected joints were normal. An electrocardiogram showed an incomplete left bundle branch block. Muscle enzyme activities were moderately elevated. A myopathic pattern was seen on the electromyogram. A muscle biopsy showed muscle fiber atrophy with peri- and endomysial fibrosis. Patient 2 was a 39-year-old man with a five-year history of isolated rigidity of the cervical spine thought to be due to a spondylarthropathy. Extension was the only movement possible at the cervical spine. The peripheral joints showed no motion range limitation. Findings were normal from radiographs of the spine and sacroiliac joints, an erythrocyte sedimentation rate determination, an electromyogram, and muscle enzyme activity assays. A muscle biopsy showed muscle fiber atrophy with peri- and endomysial fibrosis.</p><p><strong>Discussion: </strong>Rigid spine syndrome is rare in rheumatological practice and can simulate a number of other muscle and joint diseases. Peri- and endomysial fibrosis may be strongly suggestive, although nonpathognomonic. Involvement of the heart governs the prognosis.</p>","PeriodicalId":79371,"journal":{"name":"Revue du rhumatisme (English ed.)","volume":"66 6","pages":"347-50"},"PeriodicalIF":0.0,"publicationDate":"1999-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21285427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A Lohse, F Michel, B Auge, E Toussirot, D Wendling
{"title":"Vascular purpura and cryoglobulinemia after influenza vaccination. Case-report and literature review.","authors":"A Lohse, F Michel, B Auge, E Toussirot, D Wendling","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79371,"journal":{"name":"Revue du rhumatisme (English ed.)","volume":"66 6","pages":"359-60"},"PeriodicalIF":0.0,"publicationDate":"1999-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21285430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mechanisms of action of bisphosphonates.","authors":"V Breuil","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79371,"journal":{"name":"Revue du rhumatisme (English ed.)","volume":"66 6","pages":"339-43"},"PeriodicalIF":0.0,"publicationDate":"1999-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21284199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J Narváez, J A Narváez, R Ortega, A Juan-Mas, D Roig-Escofet
{"title":"Lipoma arborescens of the knee.","authors":"J Narváez, J A Narváez, R Ortega, A Juan-Mas, D Roig-Escofet","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Lipoma arborescens is a rare intraarticular lesion characterized by diffuse replacement of the subsynovial tissue by mature fat cells, producing villous transformation of the synovium. The etiology of this benign condition is unknown. The most typical site of involvement is the knee, most notably at the suprapatellar pouch, although other joints can be affected. Symptoms consist of gradual joint swelling, variable pain, motion range restriction, and intermittent joint effusions or bleeding. We report a case of lipoma arborescens and discuss the clinical features, diagnosis, and treatment of this disorder based on a literature review. Although it is rare, lipoma arborescens should be included in the differential diagnosis of patients with chronic joint swelling or hemarthrosis.</p>","PeriodicalId":79371,"journal":{"name":"Revue du rhumatisme (English ed.)","volume":"66 6","pages":"351-3"},"PeriodicalIF":0.0,"publicationDate":"1999-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21285428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hemarthrosis of the ankle revealing an aneurysm of the anterior tibial artery.","authors":"T Billey, F Marin, H Vidal, S Lassoued","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79371,"journal":{"name":"Revue du rhumatisme (English ed.)","volume":"66 5","pages":"297-8"},"PeriodicalIF":0.0,"publicationDate":"1999-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21248505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}