发布求助
文献互助 智能选刊 最新文献

Immunodeficiency最新文献

筛选
英文 中文
Bone marrow transplantation in severe combined immunodeficiency: potential and current limitations. 骨髓移植治疗严重联合免疫缺陷:潜在的和目前的局限性。
Immunodeficiency Pub Date : 1993-01-01
W Friedrich, C Knobloch, J Greher, W Hartmann, H H Peter, S F Goldmann, E Kleihauer
{"title":"Bone marrow transplantation in severe combined immunodeficiency: potential and current limitations.","authors":"W Friedrich, C Knobloch, J Greher, W Hartmann, H H Peter, S F Goldmann, E Kleihauer","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79340,"journal":{"name":"Immunodeficiency","volume":"4 1-4","pages":"315-22"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19158256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effector functions of IgG subclass antibodies. IgG亚类抗体的效应功能。
Immunodeficiency Pub Date : 1993-01-01
R G Bredius, J G Van de Winkel, R S Weening, T A Out
{"title":"Effector functions of IgG subclass antibodies.","authors":"R G Bredius, J G Van de Winkel, R S Weening, T A Out","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79340,"journal":{"name":"Immunodeficiency","volume":"4 1-4","pages":"51-3"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19158264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Control of human B cell tumor growth in SCID mice by monoclonal anti-B cell antibodies. 单克隆抗B细胞抗体对SCID小鼠人B细胞肿瘤生长的控制。
Immunodeficiency Pub Date : 1993-01-01
A Durandy, N Brousse, F Rozenberg, G De Saint Basile, A M Fischer, A Fischer
{"title":"Control of human B cell tumor growth in SCID mice by monoclonal anti-B cell antibodies.","authors":"A Durandy, N Brousse, F Rozenberg, G De Saint Basile, A M Fischer, A Fischer","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79340,"journal":{"name":"Immunodeficiency","volume":"4 1-4","pages":"73-6"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19158270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Selective impairment of CD43-mediated T cell activation in the Wiskott-Aldrich syndrome. Wiskott-Aldrich综合征中cd43介导的T细胞活化的选择性损伤。
Immunodeficiency Pub Date : 1993-01-01
K A Siminovitch, W L Greer, B Axelsson, L A Rubin, A Novogrodsky, M Peacocke
{"title":"Selective impairment of CD43-mediated T cell activation in the Wiskott-Aldrich syndrome.","authors":"K A Siminovitch,&nbsp;W L Greer,&nbsp;B Axelsson,&nbsp;L A Rubin,&nbsp;A Novogrodsky,&nbsp;M Peacocke","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The Wiskott-Aldrich syndrome (WAS) is associated with defective glycosylation and altered membrane expression of the leukocyte sialoglycoprotein CD43. To investigate whether such modifications of CD43 are relevant to T cell dysfunction in WAS, we have analyzed peripheral blood mononuclear cells from WAS patients for proliferative responses to both CD43-interacting and other T cell mitogenic stimuli. While patient lymphocytes proliferated in response to phytohaemagglutinin, concanavalin A, interleukin-2 and neuraminidase/galactose oxidase, no responses were elicited upon attempted triggering of the CD43 signalling pathway using periodate or anti-CD43 antibody. Cells from four of five patients with clinical profiles resembling, but not identical, to that of classic WAS also failed to respond to periodate or anti-CD43 antibody stimulation. These results indicate that the aberrant expression of CD43 on WAS lymphocytes is associated with selective impairment of CD43-induced T cell proliferation and that detection of this defect may be useful in the diagnosis of WAS and its variant forms.</p>","PeriodicalId":79340,"journal":{"name":"Immunodeficiency","volume":"4 1-4","pages":"99-108"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19158275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The influence of gene duplications in the human immunoglobulin heavy chain constant locus on serum levels of immunoglobulin. 人免疫球蛋白重链常数位点基因重复对血清免疫球蛋白水平的影响。
Immunodeficiency Pub Date : 1993-01-01
H Rabbani, A Bottaro, A O Carbonara, A Brusco, U Cariota, P G Olsson, C I Smith, L Hammarström
{"title":"The influence of gene duplications in the human immunoglobulin heavy chain constant locus on serum levels of immunoglobulin.","authors":"H Rabbani,&nbsp;A Bottaro,&nbsp;A O Carbonara,&nbsp;A Brusco,&nbsp;U Cariota,&nbsp;P G Olsson,&nbsp;C I Smith,&nbsp;L Hammarström","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79340,"journal":{"name":"Immunodeficiency","volume":"4 1-4","pages":"237-41"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19158283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biosynthesis of Tcr-alpha, beta and Tcr-gamma, delta/CD3 complexes. tcr - α， β和tcr - γ， δ /CD3复合物的生物合成。
Immunodeficiency Pub Date : 1993-01-01
S Bauguil-Caspar, J Arnaud, J Kuhlmann, C Geisler, B Rubin
{"title":"Biosynthesis of Tcr-alpha, beta and Tcr-gamma, delta/CD3 complexes.","authors":"S Bauguil-Caspar,&nbsp;J Arnaud,&nbsp;J Kuhlmann,&nbsp;C Geisler,&nbsp;B Rubin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Jurkat J76 clone, LYON L12.37 clone and L12.37 cells transfected with J76-alpha cDNA or J76 Tcr-alpha mutated cDNA (J79) were analysed for membrane expression of Tcr/CD3 complex using WT31 mAb (Tcr-alpha, beta) or Tcr-delta 1 mAb (Tcr-gamma, delta): LYON cells express V beta 9 bearing Tcr-beta chains. J76 Tcr-alpha cDNA transfected LYON cells have intracellular Tcr-gamma, delta chains and J79 Tcr-alpha cDNA transfected LYON cells have intracellular Tcr-alpha (M), beta chains.</p>","PeriodicalId":79340,"journal":{"name":"Immunodeficiency","volume":"4 1-4","pages":"113-6"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19158476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterization of anergy to the superantigen Staphylococcus enterotoxin B. 对超抗原葡萄球菌肠毒素B的能量表征。
Immunodeficiency Pub Date : 1993-01-01
G Dannecker, H Schultz, S Mecheri, G Sappler, K Clarke, D Niethammer, M K Hoffmann
{"title":"Characterization of anergy to the superantigen Staphylococcus enterotoxin B.","authors":"G Dannecker,&nbsp;H Schultz,&nbsp;S Mecheri,&nbsp;G Sappler,&nbsp;K Clarke,&nbsp;D Niethammer,&nbsp;M K Hoffmann","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In vivo administration of superantigens leads to activation and subsequent depletion or anergy of T cells expressing defined V beta-T cell receptors (TCR). Superantigens have therefore become intensively studied tools for examining parameters of immunoregulation and they may represent model antigens for pathogenic agents. An HIV-encoded superantigen has for example been implicated in the dramatic loss of helper T cells in AIDS. We investigated the response of V beta 8+ T cells in mice after primary and secondary exposure to the superantigen Staphylococcus Enterotoxin B (SEB).</p>","PeriodicalId":79340,"journal":{"name":"Immunodeficiency","volume":"4 1-4","pages":"137-9"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19159039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Structure of the NADPH-oxidase: membrane components. nadph氧化酶的结构:膜组分。
Immunodeficiency Pub Date : 1993-01-01
A W Segal
{"title":"Structure of the NADPH-oxidase: membrane components.","authors":"A W Segal","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79340,"journal":{"name":"Immunodeficiency","volume":"4 1-4","pages":"167-79"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19159048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Potential utility of passive immunization in preventing vertical HIV-1 transmission. 被动免疫在预防HIV-1垂直传播中的潜在效用。
Immunodeficiency Pub Date : 1993-01-01
D G Braun, M S Fung, N T Chang, T W Chang
{"title":"Potential utility of passive immunization in preventing vertical HIV-1 transmission.","authors":"D G Braun,&nbsp;M S Fung,&nbsp;N T Chang,&nbsp;T W Chang","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79340,"journal":{"name":"Immunodeficiency","volume":"4 1-4","pages":"349-51"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19158260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
T-cell dependent and T-cell independent antibody response to bacterial polysaccharides in patients with IgG2 deficiency. IgG2缺乏患者对细菌多糖的t细胞依赖性和t细胞非依赖性抗体反应。
Immunodeficiency Pub Date : 1993-01-01
P Bartmann, J Freihorst, R Seger, M Schmitt, U Wahn, V Wahn, H Jager
{"title":"T-cell dependent and T-cell independent antibody response to bacterial polysaccharides in patients with IgG2 deficiency.","authors":"P Bartmann,&nbsp;J Freihorst,&nbsp;R Seger,&nbsp;M Schmitt,&nbsp;U Wahn,&nbsp;V Wahn,&nbsp;H Jager","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79340,"journal":{"name":"Immunodeficiency","volume":"4 1-4","pages":"59-61"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19158266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信