Bulletin du cancer. Radiotherapie : journal de la Societe francaise du cancer : organe de la societe francaise de radiotherapie oncologique最新文献

{"title":"[Comparison of concomitant radiotherapy and chemotherapy with radiotherapy alone in advanced cancers of the head and neck: results of a randomized trial].","authors":"E Haddad,&nbsp;J J Mazeron,&nbsp;M Martin,&nbsp;L Vergnes,&nbsp;B Brun,&nbsp;P Piedbois,&nbsp;A Coste,&nbsp;G Lelievre,&nbsp;R Peynegre,&nbsp;J P Le Bourgeois","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>From April 1987 to October 1992, 67 patients with inoperable squamous cell carcinoma of the head and neck region were included in a randomized trial. All patients had induction chemotherapy with cisplatin (100 mg/m2, D1) and fluorouracil (1 g/m2, from D1 to D5) every three weeks for a total of three cycles. Patients were randomized to concurrent external radiation therapy (70 Gy/39 fractions/8 weeks) and chemotherapy with cisplatin (50 mg/m2 in short infusion, D1, D15, D29, D43) and fluorouracil (5 mg/kg, intra-muscular, every Monday, Wednesday and Friday) (experimental group) versus radiotherapy alone with the same modalities (control group). The followup for living patients was 14 to 60 months with a median of 42 months. Analysis of preliminary results has shown that: 1) early and late side effects are similar in both groups; 2) after completion of treatment, the percentage of patients in complete remission was 71% (20/28) in the experimental group and 43% (12/28) in the control group; this difference was statistically significant among non responders to induction chemotherapy (1/15 versus 13/20, P = 0.001), but non significant among responders (11/13 versus 7/8) and 3) there were no differences between both randomized groups in term of 3-year overall survival and of 3-year loco-regional control. Results are discussed taking into account a review of literature.</p>","PeriodicalId":79321,"journal":{"name":"Bulletin du cancer. Radiotherapie : journal de la Societe francaise du cancer : organe de la societe francaise de radiotherapie oncologique","volume":"83 2","pages":"97-103"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19662462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neutron dosimetry in French nuclear power plants. Problems and their solutions in 1995","authors":"G. Wolber ,&nbsp;Y. Guibbaud ,&nbsp;R. Dollo","doi":"10.1016/0924-4212(96)84879-1","DOIUrl":"10.1016/0924-4212(96)84879-1","url":null,"abstract":"<div><p>Personal neutron dosimetry in nuclear power plants is one of the hardest to achieve because there is no nuclear reaction that is both efficient and which ensures a suitable discrimination between 50 keV to 2 MeV fast neutrons and gamma photons. Neutron doses being low, the method used until now has been based on ambient dosimetry and the spent time in exposed areas. The advent of bubble detectors meets our immediate requirements until the direct reading electronic neutron dosimeter, which is still at the feasability research stage, can be utilized.</p></div><div><p>La dosimétrie individuelle des neutrons dans les centrales nucléaires est une des plus difficiles à réaliser car il n ‘y a pas de reaction nucléaire à la fois efficace et assurant une bonne discrimination entre les neutrons rapides de 50 keV à 2 MeV et les photons gamma. Les doses neutroniques étant faibles, la méthode utilisée jusqu’à présent a été basée sur la dosimétrie ambiante et le temps de sejour dans les zones exposées. La commercialisation des dosimètres à bulles satisfait nos besoins immédiats en attendant le dosimètre électronique à lecture directe, encore à l’etude de faisabilité.</p></div>","PeriodicalId":79321,"journal":{"name":"Bulletin du cancer. Radiotherapie : journal de la Societe francaise du cancer : organe de la societe francaise de radiotherapie oncologique","volume":"83 ","pages":"Pages 19s-26s"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0924-4212(96)84879-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19912790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Progress in the field of compounds for boron neutron capture therapy","authors":"D. Gabel","doi":"10.1016/0924-4212(96)84910-3","DOIUrl":"10.1016/0924-4212(96)84910-3","url":null,"abstract":"<div><p>For successful application of boron neutron capture therapy to the treatment of cancer, selective accumulation of boron is required. This can be achieved by the preparation of suitable substances, which must contain boron and at the same time accumulate or be retained in tumor tissue. The radiobiological rationale for selection of suitable compounds is disaussed. Examples of useful new compounds are given for which boronated analogues exist.</p></div><div><p>Une concentration sélective des composés borés au niveau des cellules cancéreuses est indispensable pour assurer le succès de la thérapie par capture de neutrons thermiques. Nous passons en revue les principales classes de composés borés susceptibles d’être utilisées en clinique et nous discutons les critères radiobiologiques permettant de les sélectionner. Un certain nombre de nouveaux composés sont présentés pour lesquels il existe des analogues bores.</p></div>","PeriodicalId":79321,"journal":{"name":"Bulletin du cancer. Radiotherapie : journal de la Societe francaise du cancer : organe de la societe francaise de radiotherapie oncologique","volume":"83 ","pages":"Pages 186s-190s"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0924-4212(96)84910-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19912796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Nice high-energy neutron facility: dosimetry intercomparisons","authors":"N. Iborra-Brassart ,&nbsp;S. Vynckier ,&nbsp;J. Herault ,&nbsp;P. Chauvel","doi":"10.1016/0924-4212(96)84902-4","DOIUrl":"10.1016/0924-4212(96)84902-4","url":null,"abstract":"<div><p>Neulron dosimetry intercomparison studies have been undertaken at the Nice neutrontherapy facility with the staff at Louvain-la-Neuve which has had wide experience in both dosimetric and radiobiological intercomparisons. Tissue equivalent (TE) ionization chambers were first calibrated in ⁶⁰Co beams and then exposed in the neulron beam at different depths in a water phantom; the largest difference observed in neutron beam measurements with all the chambers tested was 0.89%, and most of them agreed to within less than 0.5%. The gamma component at four depths was derived from measurements with Geiger-Müller counters; the results obtained with the two counters (Nice and Louvain-Ia-Neuve), expressed as a percentage of the total dose (neutron + gamma), agreed to within less than 0.03% and the value increased from 1.4 to 4.2% between 2 and 20 cm in depth.</p></div><div><p>Une intercomparaison dosimétrique et radiobiologique a été réalisée sous le faisceau de neutrons à Nice avec l’équipe de Louvain-la-Neuve qui a participé à toutes les intercomparaisons sous les différents faisceaux de neutrons en Europe, en Afrique et aux États-Unis. Les chambres d’ionisation, à tissu équivalent (TE) ont d’abord été étalonnées sous faisceau de ⁶⁰Co puis des mesures ont été réalisées à différentes profondeurs, dans un fantôme d’eau, sous le faisceau de neutrons; les résultats obtenus diffèrent au maximum de 0,89% entre toutes les chambres et quelles que soient les profondeurs; l’écart entre la plupart des mesures est inférieur à 0,5%. La composante gamma a été étudiée à quatre profondeurs différentes avec des compteurs Geiger-Muller; les résultats sont exprimés en pourcentage de la dose totale (neutron + gamma). Les valeurs obtenues avec les deux compteurs ne diffèrent que par 0,03% au maximum et la composante gamma augmente de 1,4% à 4,2% entre 2 et 20<!--> <!-->cm de profondeur.</p></div>","PeriodicalId":79321,"journal":{"name":"Bulletin du cancer. Radiotherapie : journal de la Societe francaise du cancer : organe de la societe francaise de radiotherapie oncologique","volume":"83 ","pages":"Pages 153s-156s"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0924-4212(96)84902-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19914160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Portal imaging: the legal point of view].","authors":"P Martin","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79321,"journal":{"name":"Bulletin du cancer. Radiotherapie : journal de la Societe francaise du cancer : organe de la societe francaise de radiotherapie oncologique","volume":"83 4","pages":"414-7"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20034141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Non-Hodgkin's lymphoma in adults. Therapeutic strategy].","authors":"J P Le Bourgeois,&nbsp;F Reyes","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79321,"journal":{"name":"Bulletin du cancer. Radiotherapie : journal de la Societe francaise du cancer : organe de la societe francaise de radiotherapie oncologique","volume":"83 4","pages":"258-64"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20034205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Treatment of bone metastases].","authors":"G Kantor,&nbsp;J M Simon","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79321,"journal":{"name":"Bulletin du cancer. Radiotherapie : journal de la Societe francaise du cancer : organe de la societe francaise de radiotherapie oncologique","volume":"83 4","pages":"275-6"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20034208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Radiotherapy of bone metastases. A review of the literature].","authors":"J M Simon","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79321,"journal":{"name":"Bulletin du cancer. Radiotherapie : journal de la Societe francaise du cancer : organe de la societe francaise de radiotherapie oncologique","volume":"83 4","pages":"290-8"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20034211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Hyperfractionated and accelerated radiotherapy in head and neck cancers: results of the EORTC trials and impact on clinical practice].","authors":"J C Horiot,&nbsp;P Bontemps,&nbsp;A C Begg,&nbsp;R Le Fur,&nbsp;W Van den Bogaert,&nbsp;M Bolla,&nbsp;T N'Guyen,&nbsp;D Van den Weijngaert,&nbsp;J Bernier,&nbsp;A Lusinchi,&nbsp;D Stuschke,&nbsp;D Lopez Torrecilla,&nbsp;B Jancar,&nbsp;L Collette,&nbsp;M Van Glabbeke,&nbsp;M Pierart","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79321,"journal":{"name":"Bulletin du cancer. Radiotherapie : journal de la Societe francaise du cancer : organe de la societe francaise de radiotherapie oncologique","volume":"83 4","pages":"314-20"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20034214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Quality control in electronic portal imaging devices. Commission Imagerie, Société française des physiciens d'hôpital].","authors":"J Lescrainier,&nbsp;M Grelot,&nbsp;C Boutinaud,&nbsp;H Bouscayrol,&nbsp;I Champeaux,&nbsp;C Ginestet","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79321,"journal":{"name":"Bulletin du cancer. Radiotherapie : journal de la Societe francaise du cancer : organe de la societe francaise de radiotherapie oncologique","volume":"83 4","pages":"409-13"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20034228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}