alexandria journal of veterinary sciences最新文献

{"title":"Clinico-pathological Evaluation of Hepatoprotective Effect of Dandelion and Ginkgo-biloba Extract against Thioacetamide Induced Liver Damage","authors":"H. Shaaban, E. Mehana, S. Oda, Hossam G. Tohamy, Dina Karim","doi":"10.5455/ajvs.124405","DOIUrl":"https://doi.org/10.5455/ajvs.124405","url":null,"abstract":"This study was carried outto investigatethe ameliorative effect of both of Dandelion and Ginko.biloba extract on liver toxicities induced by thioacetamide (TAA) in male albino rats.Sixty male albino rats were divided into sixgroups (10 rats pereach).Group 1 (Negative control): which received 1 ml of saline orally and 1ml of saline intra-peritoneal (I/P),Group 2: received TAA for induction of hepatic injuryGroup 3:received TAA+ ginkgo biloba extract (50 mg/ b.wt.),Group 4: received TAA+ ginkgo biloba extract (100 mg/ kg b.wt.).Group 5: which received TAA + dandelion extract (250 mg/ kg b.wt).Group 6: which received TAA+ dandelion extract (500 mg/ kg b.wt.).TAA was administrated by I/P route at dose level of 250mg/kg b.wt , extracts were administrated orally, they were administrated 3 times/week for 4 weeks. The obtained results revealed that intoxication with TAAshowed a significant elevation in serum liver enzymes activity, total bilirubinplussignificant decrease in serum levels of total proteins andalbumin, significant increase in total cholesterol and triglycerides.At the same time ,intoxication with TAA exhibited severe oxidative damged stress ,represented by a significant increase in hepatic level of malondialdehyde (MDA)as well asa significant decrease in reduced glutathione (GSH).The characteristic pathological changes were represented by ,(TAA),severe degenerative andnecrotic alterationsin the hepatocytes. The treatment with G.biloba and D- in different treateddosesattenuatedTAA-induced,serum biochemical alterations, oxidative stressand histopathological changes in liver.","PeriodicalId":7928,"journal":{"name":"alexandria journal of veterinary sciences","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83145435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intestinal Parasites among Asymptomatic Food Handlers in a Tertiary Institution in Owo, Ondo State, Nigeria","authors":"O. Bolaji, O. Adekunle, Teslim Adebayo, A. Ajayi, Busayomi Dada","doi":"10.5455/ajvs.120293","DOIUrl":"https://doi.org/10.5455/ajvs.120293","url":null,"abstract":"ABSTRACT Incidence of intestinal parasites has been described as one of the most common problems of developing countries like Nigeria. This study was carried out to determine the possible presence of parasites amongst asymptomatic food handlers in tertiary institution in Owo. One hundred and twenty three (123) stool samples were randomly collected from food vendors in Achievers University, Owo. Also, questionnaires were administered and collated. The samples were transported to the University Parasitology Laboratory within 1 hour of production and examined microscopically using physiological saline and iodine direct mount and formal ether concentration techniques. Out of the 123 stool samples analyzed, 20 were infected with gastrointestinal parasitic organisms, giving a prevalence of 16.26%. Three different parasites were identified: Ascaris lumbricoides (12.20%), Giardia lambia (5.67%), and Entamoeba histolytica (3.25%). The prevalence with respect to gender showed that parasitic infestation was higher in females (9.76%) than in males (6.50%). The parasitic infestation was higher in age groups 36–45 years (7.32%), followed by age groups 18–25 years (5.69) and least in age group 26–35 years (3.25%). The parasitic infestation was higher among subjects who sell cooked food and snacks (6.50%), followed by those who sell cooked food only (4.88%), and lastly 2.44% among those that sell snacks and roasted meat respectively. In conclusion, this study confirmed the presence of intestinal parasitic infection among food handlers in Achievers University Owo, Ondo State. Good hygiene and safe food-handling should be exercised by food handlers.","PeriodicalId":7928,"journal":{"name":"alexandria journal of veterinary sciences","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89320468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Foot and Mouth disease outbreaks in Egypt and other African countries","authors":"A. Byomi, S. Zidan, E. Sakr, Nourhan Eissa, Yumna Elsobky","doi":"10.5455/ajvs.153493","DOIUrl":"https://doi.org/10.5455/ajvs.153493","url":null,"abstract":"Foot and mouth disease is endemic in nearly all countries of Africa. The highest prevalence of FMD was detected in Mauritius and Comoros while the lowest prevalence was reported in Mozambique, Namibia, Angola, Malawi, South Africa, Mauritania, Botswana, and Uganda. Serotype A was circulated in 11 African countries. The results showed that serotype A was more prevalent in the northern and eastern parts of Africa than in the southern and western parts. The highest prevalence of serotype A was found in Algeria, Egypt, and Tunisia, while the lowest prevalence was observed in Uganda. Co-circulation of serotype A with other serotypes has been observed in some countries, such as Egypt, Algeria, Tunisia, Libya, Sudan, Zambia, Democratic Republic of the Congo, Eritrea, Ethiopia, and Kenya. This is likely due to the illegal movement of livestock between these countries. Serotype O was the most predominant serotype in Africa. The results found that serotype O was more prevalent in the northern, eastern, and western parts of Africa than in the southern part. The highest prevalence of serotype O was recorded in Mauritius and Comoros, while the lowest prevalence was found in Eritrea, Egypt, Ethiopia, Kenya, Sudan, and Zambia. Unlike Serotype A and O, SAT1 was distributed in 6 African countries. The results revealed that serotype SAT1 was more prevalent in the eastern and southern parts of Africa than in the western and northern parts. The highest prevalence of serotype SAT1 was reported in Zimbabwe, while the lowest prevalence was in Botswana and South Africa. the study also found that the circulating serotype SAT1 was the same genetically in Zimbabwe, Tanzania, Kenya, and South Africa. This suggests that the virus is being transmitted between these countries, either through the illegal movement of livestock or through the movement of wild animals. Serotype SAT2 was widely distributed across African countries. The highest probability of infection of serotype SAT2 was found in Egypt, while the lowest probability of infection was observed in Mozambique, Angola, Namibia, Malawi, Zambia, Mauritania, Botswana, and South Africa. SAT3 serotype being the lowest circulating serotype of FMDV in Africa, it was distributed only in 3 African countries. The results stated that serotype SAT3 was only found in three African countries: Namibia, South Africa, and Zimbabwe. Based on the raster risk map, northern, eastern, and southern African countries were determined to have the highest predicted risk of FMD spatial occurrence during the study period.","PeriodicalId":7928,"journal":{"name":"alexandria journal of veterinary sciences","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88035697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fitness of Some Meat Products for Human Consumption in Relation to Their Physico-Chemical and Bacteriological Quality in the Egyptian Market","authors":"Zakaria Bayoumi, A. Edris, Hossam Hossam, M. Latif, R. Shawish","doi":"10.5455/ajvs.144651","DOIUrl":"https://doi.org/10.5455/ajvs.144651","url":null,"abstract":"Physico-chemical and microbiological quality of meat products are the main acceptability issue to the consumers. So, the current study aimed to determine the acceptability and fitness of four restructured meat products for human consumption based on their sensory, keeping quality and bacteriological quality trough examination of one-hundred and sixty random samples of minced meat, sausage, beef burger and frankfurter (40 of each), which were collected from different supermarkets located in Menoufia governorate, Egypt, and were examined according to standard guidelines. Results revealed that the examined burger and frankfurter samples revealed higher acceptability scores than those of minced meat and sausage samples. In addition, although it revealed lower pH values, minced meat samples had the lowest keeping quality with significant higher TVN and TBA values than the recorded results of the other examined samples. Moreover, the bacteriological examinations revealed detection of Salmonella and E. coli were detected in 20% and 25%; 17.5% and 20%; 12.5% and 12.5%; 5.0% and 7.5% for the examined minced meat, sausage, burger and frankfurter samples, respectively. In addition, S. aureus was counted (CFU/g) in the examined samples with mean values of 1.98×103, 9.64×102, 5.03×102 and 2.16×102 CFU/g for the same examined samples, respectively. Furthermore, minced meat was the most contaminated samples with Pseudomonas and Aeromonas spp., where P. fluorescens and A. sorbia were the most isolated strains in the examined samples. Meat and meat product safety and acceptability are of a major concern as commercial foods. Minced meat showed lower acceptability levels than the other examined samples, with higher contamination levels. So, monitoring of the chemical and bacteriological quality of restructured meat products is significantly helping in its improvement.","PeriodicalId":7928,"journal":{"name":"alexandria journal of veterinary sciences","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90175252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Spirulina Platensis Efficacy Against Local Field Vvibdv Challenge in Broiler Chickens","authors":"Mahmoud Sedeik, Nahed Shall, Ahmed Salaheldin, Raghda Goda, Ashraf Awad","doi":"10.5455/ajvs.148911","DOIUrl":"https://doi.org/10.5455/ajvs.148911","url":null,"abstract":"The antiviral and immunostimulant effect of dietary supplementation of Spirulina platensis (SP) against Infectious bursal disease (IBD) was assessed as follows; 126 one-day-old cobb broiler chicks were randomly distributed into six groups (21 birds/group with three replicates, 7 birds each): negative control (non-vaccinated, and non-challenged ; NC), positive control (non-vaccinated, and challenged; PC), vaccinated control (vaccinated, and challenged; VC), Spirulina 0.1% (vaccinated, 0.1% SP-supplemented, and challenged; VSP-0.1), Spirulina 0.3% (vaccinated, 0.3% SP-supplemented, and challenged; VSP-0.3), and Spirulina 0.5% (vaccinated, 0.5% SP-supplemented, and challenged; VSP-0.5). The chicks in NC, PC, and VC groups were not supplemented with SP. All vaccinated groups, regardless SP supplementation, showed significant improvement of body weight gain (19% in 0.3% SP) and FCR during IBDv challenge (10 dpc) (P˂0.05). On the 10th dpc, IBD ELISA titer in SP-supplemented groups were decreased (P>0.05) than that of G3, suggesting an antiviral efficacy of SP. This antiviral activity was evident by the viral RNA load in the cloacal swabs as well. The viral shedding peak was on the 5th day pc which was significantly decreased on G4-6 (P˂0.05) in comparison to G2 and G3. Also, the bursal ratio was improved in SP supplemented groups comparable to G3. Moreover, in unchallenged broilers, the gene expression of INF-γ and IL-18 were upregulated while that of IL-10 was downregulated in spleen of SP-supplemented chicks. Finally, severe histopathological lesions of kidneys, bursa, thymus, and spleen were observed in G2 which moderately minimized in G3 and were more alleviated in SP-supplemented groups. Collectively, SP supplementation improved body weight gain and decreasing viral shedding with antiviral activity. The mechanisms of SP against IBDV challenge may include cell-mediated immunity promoting effect, antiviral activity, and/or anti-inflammatory effect that should be further studied","PeriodicalId":7928,"journal":{"name":"alexandria journal of veterinary sciences","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135447648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Spirulina Supplementation on Some Immune and Biochemical Parameters of Nile Tilapia Under Cold Stress","authors":"Hoda AbdAllah, Abd Hamed, Mohamed Bakry, Ibtisam Eldin, Magda AbdElal, Dalia Mohamed, Sahar Mohamady","doi":"10.5455/ajvs.164820","DOIUrl":"https://doi.org/10.5455/ajvs.164820","url":null,"abstract":"Climatic change is a grave and growing threat to natural systems and aquatic species. Cold stress has caused a great worldwide economic loss in aquacultures worldwide. This study aimed to evaluate the effect of dietary Spirulina (Arthrospira platensis) on immunobiochemical parameters, antioxidants, some metabolic gene expressions, and histological structure of liver and kidney of Nile tilapia (Oreochromis niloticus) under cold stress. One hundred and sixty Nile tilapia were divided into eight groups (10 fish per aquarium) in two replicates. The first four groups were maintained at 26 °C whereas, the rest were subjected to 17 °C cold stress. They were fed three spirulina-contained diets (0.75, 1.5, and 3%) and a control diet for three weeks. Blood and tissue samples were collected from all groups after exposure to cold stress. The results of the cold-stressed group that fed control diet showed a significant decreases in the serum level of cortisol, catalase, superoxide dismutase, phagocytic activity, tumor necrotic factor α, Interleukin 1β, Interleukin 6, and Interleukin 17. Also, it explored a significant increased serum level of heat shock protein 70, glucose, Interleukin 10, and malondialdehyde, beside up-regulation of Phosphoenolpyruvate carboxykinase 1, and mitochondrial transcription factor A genes. In addition to, alteration of liver and kidney biomarkers with severe histopathological perturbations of liver and kidney were detected. Dietary Spirulina supplementation at 0.75% during cold stress ameliorate the immune and antioxidant status, biochemical parameters and protecting the integrated tissue architecture from oxidative damage of Nile tilapia.","PeriodicalId":7928,"journal":{"name":"alexandria journal of veterinary sciences","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135261761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinicopathological study on some vaccines in Barki ewes","authors":"A. Darwish, Ahmed Sify, T. Allam","doi":"10.5455/ajvs.142770","DOIUrl":"https://doi.org/10.5455/ajvs.142770","url":null,"abstract":"Vaccines are the most effective method for animal immunization against infectious diseases. This work aimed to study the effect of some vaccines commonly, used in sheep, on some innate immunological and clinicopathological parameters. For this purpose, forty-five Barki ewes were housed at the sustainable development Centre of Matrouh resources farm. They were divided into: Pox group: fifteen ewes were injected with live-attenuated pox vaccine. FMD+RVF group: fifteen ewes were injected separately with two vaccines (polyvalent inactivated foot and mouth disease oil adjuvant vaccine and rift valley inactivated vaccine). Ultrabac group: fifteen ewes were injected with 2.5 ml bacterial toxoid (Ultrabac® 8, Zoetis). Blood samples were collected then immunological and clinicopathological parameters were estimated and statistically analyzed. The three studied groups showed a significant (P˂0.05) increase in the activity of pro-inflammatory cytokines, ceruloplasmin, and oxidative stress, associated with serious clinicopathological changes (anemia, leukocytosis, increased liver and kidney functions, hyperglobulinemia, hypoalbuminemia). These alterations peaked on the 14th day, and subsequently moved towards their baseline values. They were more prominent and sustained in the Ultrabac group (with selective hyperproteinemia) than in the other two groups. The FMD+RVF group displayed a higher degree of cytokines activity, APR, oxidative stress, leukocytosis, and AST values than the Pox group. Conclusion: Sheep vaccination evokes an innate immune response which results in clinicopathological changes. These alterations are more pronounced in bacterial and combined vaccines than viral and single vaccines. The first 14 days after vaccination is a critical period and needs proper management.","PeriodicalId":7928,"journal":{"name":"alexandria journal of veterinary sciences","volume":"77 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75331591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanostructured Lipid Carrier Technology to Enhance Natural Extracts Delivery: Potential of Skin Regeneration","authors":"Ola Elkhateeb, M. Badawy, H. Ahmed, M. Kammar, H. Elkhenany","doi":"10.5455/ajvs.107122","DOIUrl":"https://doi.org/10.5455/ajvs.107122","url":null,"abstract":"Natural extracts (EXTR) have been proven to effectively regenerate tissues however may need long treatment periods. Here in this study, we investigated curcumin (CURC) and Propolis (PROP) encapsulated in the form of nanostructure lipid carrier (NLC) form. The results have shown that this technology has preserved a higher flavonoid content compared to crude EXTR from both materials under investigation. Interestingly, phenolic content in PROP NLC was significantly higher than EXTR, however, CURC NLC did not show the same pattern compared to its relative EXTR. Further investigations are needed to prove the efficacy of this PROP and CURC NLC as antioxidant, antibacterial and wound healing proficiency.","PeriodicalId":7928,"journal":{"name":"alexandria journal of veterinary sciences","volume":"95 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84398439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Pathogenic Intestinal Parasites and Enteropathogenic Bacteria in Faecal Samples Obtained from Abattoirs in Ogbomoso, Oyo State, Nigeria","authors":"O. Bolaji, O. Adekunle, A. Ajayi, Abolaji T. Adeyemo, A. Ojewuyi, A. Ibrahim, A. Adeyemo, A. Ajayi, Akinwumi Akindele, O. Adeyeba","doi":"10.5455/ajvs.148234","DOIUrl":"https://doi.org/10.5455/ajvs.148234","url":null,"abstract":"This study was undertaken to determine the prevalence of intestinal parasites and enteropathogenic bacteria in fecal effluents from abattoir. A total of 162 samples were examined out of which 70 faecal samples were collected from cow, 35 from pig, 35 from goat and 22 from sheep. These samples were processed using standard parasitological techniques ( macroscopy, microscopy; the Formol-ether concentration technique and zinc sulphate floatation technique) and bacteriological (culture, Gram reaction and biochemical characterization). Data was analyzed using Chi-square test. One hundred and eleven (111) samples were found positive with one or more parasites giving an overall prevalence of 68.5%. Pigs recorded the highest prevalence of 77.1% for intestinal parasites, followed by goat and cow with prevalence of 68.6% and 65.7% respectively and the least prevalence was observed in sheep, 63.6%. The prevalence of different parasites encountered include Fasciolopsis buski (8.6%), Hookworm (8.0%), Ascaris suum (7.4%), Balantidium coli (7.4%), Fasciola hepatica (7.4%), Entamoeba histolytica (7.4%), Taenia species (6.2%), Fasciola gigantica (4.3%) and Toxocara species (1.2%). Mixed infections of Balantidium coli+Entamoeba histolytica has the highest frequency of 4(2.5%) followed by Entamoeba histolytica+Hookworm and Toxocara species+Balantidium coli with the frequency of 3(1.9%) each, Ascaris suum+Taenia species, Ascaris suum+Taenia species+Hookworm and Balantidium coli+Fasciola hepatica with a frequency of 2(1.2%) each and Toxocara species+Balantidium coli recorded the lowest frequency of 1(0.6%). Also the prevalence of potentially pathogenic bacteria and yeast cells encountered include Bacillus species (29.6%), Escherichia coli (23.5%), Campylobacter species (17.3%), Pseudomonas aeruginosa (11.1%), Staphylococcus aureus (10.5%), Yeast cells (4.9%) and Staphylococcus species (3.1%). This study shows high degrees of fecal contamination of intestinal parasites and bacterial agents. As a result of this sanitary measures and Government policy should be strictly employed as this will go a long way to help check environmental contamination and reduce potential risks posed by these pathogens.","PeriodicalId":7928,"journal":{"name":"alexandria journal of veterinary sciences","volume":"99 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89543429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antimicrobial Resistance Profile of Aerobic Nasal Microflora of Nigerian Indigenous Pigs","authors":"O. Omotosho, Sandra Ukatu, M. Okandeji, O. Okunlade, A. Adeola, B. Emikpe","doi":"10.5455/ajvs.70219","DOIUrl":"https://doi.org/10.5455/ajvs.70219","url":null,"abstract":"There is increasing global threat of antimicrobial resistance (AMR) mostly with regards to the exchange of potentially harmful microbes across human and animal populations. There is also limited information in literature on the microbial population of Nigerian Indigenous Pigs (NIP). This study was designed as a preliminary investigation to provide baseline information on the AMR profile of nasal flora of NIP. Thirty-one nasal swabs were collected from NIPs on the Teaching and Research Farm, University of Ibadan, Nigeria. Bacteria were isolated, characterized and identified using cultural and biochemical characteristics. Antibiotic Susceptibility Testing (AST) was carried out on the pure strains of bacteria using the gram positive and negative antibiotic sensitivity discs. Three media were used for isolation; Nutrient agar, MacConkey agar and Mannitol Salt Agar. Data were analysed using descriptive statistics. Ten multi-drug resistant bacteria were identified; Staphylococcus aureus (96.8%), Escherichia coli (87.1%), Shigella species (80.6%), Bacillus species 51.6% (16/31) and Serratia species 51.6% (16/31) were the most frequently isolated. Of the isolated organisms, the gram positive organisms showed high resistance to Ceftazidime (81.1%), Ceftriaxone (86.9%), Cloxacilin (93.4%), Augmentin (100%), and Cefuroxime (100%) with considerable sensitivity to Ofloxacin (74.6%) and Gentamicin (80.9%). While the gram negative bacteria were highly resistant to Tetracycline (77.6%), Cefuroxime (90%), Ceftriaxone (87.1%), Sulbactarm (83.2%) and Ampiclox (85.7%) with considerable sensitivity to Levofloxacin (78.9%) and Nitrofurantoin (93.4%). This study reveals a high microbial load of AMR bacteria in the nasal cavity of NIPs making them a possible reservoir. These findings unveil the need for genetic data to determine the pattern, extent and basis of AMR resistance in the nasal flora of NIPs. We therefore recommend more rational use of antibiotics in pigs and other food animals to safeguard animal and human health.","PeriodicalId":7928,"journal":{"name":"alexandria journal of veterinary sciences","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91248813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}