Metabolic, pediatric, and systemic ophthalmology最新文献_第8页

Metabolic, pediatric, and systemic ophthalmology Pub Date : 1982-01-01

Y Ne'man

引用次数: 0

Decreasing B-wave amplitude noted in erg in one type of retinitis pigmentosa. 一种色素性视网膜炎的b波振幅下降。

Metabolic, pediatric, and systemic ophthalmology Pub Date : 1982-01-01

D V Schoon, M Harris

引用次数: 0

Disease of the ornithine-proline pathway: delta 1-pyrroline-5-carboxylate reductase deficiency in the retina of retinal degeneration mice. 鸟氨酸-脯氨酸途径疾病:视网膜变性小鼠视网膜1-吡咯-5-羧酸还原酶缺乏。

Metabolic, pediatric, and systemic ophthalmology Pub Date : 1982-01-01

T Matsuzawa

引用次数: 0

Visual development: early experience with torsionally disparate images. 视觉发展:早期对扭曲的不同图像的体验。

Metabolic, pediatric, and systemic ophthalmology Pub Date : 1982-01-01

M Podell, M R Isley, P G Shinkman, D C Rogers

{"title":"Visual development: early experience with torsionally disparate images.","authors":"M Podell, M R Isley, P G Shinkman, D C Rogers","doi":"","DOIUrl":"","url":null,"abstract":"Environmental influences on the developing primary visual cortex of kittens were studied by exposing dark reared kittens to prism-induced interocular rotational disparities of 32 degrees, the visual input rotated equally and oppositely in the two eyes. The present report describes preliminary results obtained from two kittens that received this altered visual exposure during 1-6 hours each day from 4 until 12 weeks of age. Subsequent single-unit recordings from the striate cortex revealed three major changes in functional cortical visual physiology. First, there was a disruption in binocularity, with many more cells being monocularly driven in the rotated conditions compared to control conditions. Second, there was an increased variance in the distribution of cells' interocular differences in preferred stimulus orientation (interocular orientation disparity, or IOD) as compared to control conditions. Third, changes were noted in orientation tuning and in the distribution of orientation preferences: cells most selective for orientation tended to be in the extreme ocular dominance groups, and monocular cells were often the most highly selective; also, both binocular and monocular cells showed a tendency for preferred orientations for both eyes to fall near the horizontal or vertical (+/- 22.5 degrees). Thus, a large optically-induced orientation disparity between the two eyes' visual fields during the critical period can modify the characteristics of striate cortical neurons, particularly binocularity and IOD. In addition, these results indicate that an inherent cortical mechanism may ensure the encoding of horizontal and vertical orientation specificities for a subclass of primary visual cortical neurons.","PeriodicalId":79237,"journal":{"name":"Metabolic, pediatric, and systemic ophthalmology","volume":"6 3-4","pages":"273-83"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18198562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Orientation disparity and plasticity of cortical cells in kittens following surgical rotation of the eye. 小猫眼旋转手术后皮质细胞的取向差异和可塑性。

Metabolic, pediatric, and systemic ophthalmology Pub Date : 1982-01-01

U Yinon

{"title":"Orientation disparity and plasticity of cortical cells in kittens following surgical rotation of the eye.","authors":"U Yinon","doi":"","DOIUrl":"","url":null,"abstract":"We have studied the effect of surgically induced monocular rotation of the eye on cells in visual area 17 of normal kittens (N = 420 cells) and of kittens monocularly deprived (N = 296 cells) at early (1-1.5 months) or late (3 months) ages. The receptive fields of cortical neurons in monocularly deprived kittens of the early operated group were abnormal in shape, a condition which is reflected by the high proportions of cells missing orientation (46.9%) and direction (47.7%) specificity when driven through the rotated eye. In addition, many cells (46%) were visually inactive in these kittens. The proportions of the above cell groups were less pronounced in the operated kittens with binocular vision and in all late operated kittens, indicating a specific effect of the rotation itself. In the early operated kittens with binocular vision, the rotation resulted in 35.9% binocular cells in the hemisphere contralateral and 40.0% in the hemisphere ipsilateral to the rotated eye. The results for the monocularly deprived early operated kittens were 42.8% and 21.5% respectively. Thus, the rotation was effective in limiting the influence of the deprivation to only the contralateral hemisphere. The distribution of the cells in accordance with their receptive field orientations following correction for the surgical rotation shows a considerable disturbance to orientation specificity, as reflected by the wide range of angular disparities found for the binocular cells. While for three kittens (28 cells) a tendency toward the zero line was found, for four kittens (28 cells) we could not prove, it indicating that a compensation for the interocular difference surgically induced is not seen.","PeriodicalId":79237,"journal":{"name":"Metabolic, pediatric, and systemic ophthalmology","volume":"6 3-4","pages":"237-50"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18200029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0