Elber Alberto Soler Arias , Víctor Alejandro Castillo
{"title":"Síndrome de Cushing adrenal dependiente de hormona luteinizante","authors":"Elber Alberto Soler Arias , Víctor Alejandro Castillo","doi":"10.1016/j.raem.2016.05.006","DOIUrl":"10.1016/j.raem.2016.05.006","url":null,"abstract":"<div><p>Luteinising hormone (LH) and human chorionic gonadotropin (hCG) can induce steroidogenesis, hyperplasia, and adrenal tumorigenesis through the stimulus of the constitutive LH receptor (R-LHCG) within the adrenal cortex. The pathophysiological mechanisms of luteinising hormone-dependent Cushing's syndrome are not completely understood, but the ontogenic relationship between the adrenal cortex and the gonads, with mutual participation of different genes, transcription factors and steroidogenic enzymes cited as a possible cause, is well-recognised. SCa-LH has been described in pregnant women, as a result of hCG stimulus, and in post-menopausal women, due to increased levels of LH, as well as in ferrets after gonadectomy.</p></div>","PeriodicalId":78598,"journal":{"name":"Revista argentina de endocrinologia y metabolismo","volume":"53 1","pages":"Pages 36-41"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.raem.2016.05.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54996179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cintia Silvina Palmero , María Marta López , Sandra Paola Zelaya , Lia Marisol Díaz , Laura Elisa Morresi , Enrique Muñoa , Juan Manuel Cohen Sabban , Marcos Alejandro Cohen Sabban
{"title":"Incidencia de cáncer de tiroides en la provincia de Río Negro","authors":"Cintia Silvina Palmero , María Marta López , Sandra Paola Zelaya , Lia Marisol Díaz , Laura Elisa Morresi , Enrique Muñoa , Juan Manuel Cohen Sabban , Marcos Alejandro Cohen Sabban","doi":"10.1016/j.raem.2016.05.004","DOIUrl":"10.1016/j.raem.2016.05.004","url":null,"abstract":"<div><h3>Introduction</h3><p>The incidence of thyroid cancer (TC) has been increasing over the last twenty years or so. There are few data in our country with regard to the epidemiology of this disease.</p></div><div><h3>Objective</h3><p>To assess the incidence of thyroid cancer in the province of Río Negro (RN) for the period 2004- 2013.</p></div><div><h3>Methods</h3><p>All histological reports with TC diagnosis within the study period in the department of General Roca, which represents 50% of the population of RN province, were assessed. Incidence rates were calculated, and the study period was divided into two five-year segments to evaluate the possibility of an increased incidence. Other variables were also assessed, including age, sex, histological type, multicentricity, presence of metastatic lymph nodes, diagnosis and treatment, and whether in public or private health institutions.</p></div><div><h3>Results</h3><p>There was an incidence of 6.77 new cases/100,000 inhabitants/year, (10.76 in women and 2.48 in men).</p><p>Evaluation of the number of TC cases per five-year period showed 41 cases in the first period and 116 in the second, with an incidence rate that increased from 4.52 to 9.30/100,000 inhabitants/year. Almost all cases (98.7%) were found to be Papillary Thyroid Carcinoma, 22.9% showed metastatic lymph nodes, and 36.9% were multifocal. Also, of the total population in study, 80.2% were women, and 75.8% were treated in the private health sector. Mean tumour volume was 19.9<!--> <!-->mm<!--> <!-->±<!--> <!-->14.32<!--> <!-->mm, with no significant differences between the two study periods. An increase from 27% to 35% was observed in the proportion of tumours smaller than 10<!--> <!-->mm in the second period. Although this increase was not statistically significanct (<em>P</em> <!-->=<!--> <!-->.35), a rising trend is observed.</p></div><div><h3>Conclusion</h3><p>Incidence of TC in the province of RN is similar to that reported in the literature and an increase in its incidence was observed during the study period.</p></div>","PeriodicalId":78598,"journal":{"name":"Revista argentina de endocrinologia y metabolismo","volume":"53 1","pages":"Pages 16-21"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.raem.2016.05.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54996141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrea Elena Iglesias Molli , Andrea Millán , Jorge Vilariño , Claudio Daniel González , Marta Sereday , Irma Slavutsky , Gloria Edith Cerrone , Gustavo Daniel Frechtel
{"title":"Análisis de la longitud de los telómeros en obesos metabólicamente sanos","authors":"Andrea Elena Iglesias Molli , Andrea Millán , Jorge Vilariño , Claudio Daniel González , Marta Sereday , Irma Slavutsky , Gloria Edith Cerrone , Gustavo Daniel Frechtel","doi":"10.1016/j.raem.2016.05.005","DOIUrl":"10.1016/j.raem.2016.05.005","url":null,"abstract":"<div><p>Obesity is the principal component in Metabolic Syndrome (MetS) and determines the progression of metabolic complications. Metabolically healthy obese individuals (MHO) seem to be protected against those complications. Telomere length (TL), as a novel marker of cellular aging, has a complex relationship with MetS. The principal aim of this study was to investigate TL in MHO, and to study the association between TL and the number of MetS components.</p><p>A study was conducted on 398 women (mean age: 46.76<!--> <!-->±<!--> <!-->15.47 years; range: 18 - 86 years), grouped according to the number of MetS components (0, 1<!--> <!-->+<!--> <!-->2, MetS), a group of normal-weight individuals with 0 MetS components (NW0), and a group of obese without MetS (MHO).</p><p>No differences were found in the TL of the MHO group compared to the NW0, but it was significantly higher than that of individuals with MetS (<em>P</em> <!-->=<!--> <!-->.032). A decrease in TL was observed with a progressive increase in the number of MetS components (<em>P</em> <!-->=<!--> <!-->.004), whereas the group of individuals without MetS components had significantly longer TL than the groups with 1 and 2 components (<em>P</em> <!-->=<!--> <!-->.027), and MetS (<em>P</em> <!-->=<!--> <!-->.003).</p><p>Shorter TL is not associated with MHO, but is related to MetS and with an increased number of metabolic abnormalities.</p></div>","PeriodicalId":78598,"journal":{"name":"Revista argentina de endocrinologia y metabolismo","volume":"53 1","pages":"Pages 22-28"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.raem.2016.05.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54996155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J M Cervino, J Maggiolo, J P Saralegui Buela, M L Iraola
{"title":"[2 cases of papilliferous thyroid carcinoma associated with anaplastic carcinoma].","authors":"J M Cervino, J Maggiolo, J P Saralegui Buela, M L Iraola","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":78598,"journal":{"name":"Revista argentina de endocrinologia y metabolismo","volume":"16 4","pages":"193-203"},"PeriodicalIF":0.0,"publicationDate":"1970-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16600910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Current status of our knowledge on prolactin].","authors":"J Moratõ Manaro","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":78598,"journal":{"name":"Revista argentina de endocrinologia y metabolismo","volume":"16 4","pages":"205-14"},"PeriodicalIF":0.0,"publicationDate":"1970-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16092362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nuclear vacuolization of the parafollicular cells of the thyroid gland in a curious disease of bovines.","authors":"J Ruager, F C Iturriza, A A Martĩn","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":78598,"journal":{"name":"Revista argentina de endocrinologia y metabolismo","volume":"16 4","pages":"159-64"},"PeriodicalIF":0.0,"publicationDate":"1970-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16092361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Functional thyroid nodules].","authors":"J M Cervino, S Cervino, P Garra","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":78598,"journal":{"name":"Revista argentina de endocrinologia y metabolismo","volume":"16 4","pages":"173-92"},"PeriodicalIF":0.0,"publicationDate":"1970-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16600909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Production of fatty acids by adipose tissue of obese patients].","authors":"J M Domìnquez","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":78598,"journal":{"name":"Revista argentina de endocrinologia y metabolismo","volume":"16 4","pages":"165-71"},"PeriodicalIF":0.0,"publicationDate":"1970-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16605660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D Davidovich, H Stigliano, J R Garcĩa, D Felman, R E Adriãn
{"title":"[Study of thyroid function in 20 inhabitants of a zone with an excess of iodine in the drinking water].","authors":"D Davidovich, H Stigliano, J R Garcĩa, D Felman, R E Adriãn","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":78598,"journal":{"name":"Revista argentina de endocrinologia y metabolismo","volume":"16 3","pages":"75-9"},"PeriodicalIF":0.0,"publicationDate":"1970-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16606589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Positive sex chromatin in the male population].","authors":"J Z Albescũ, R Spada, B M De Behar, C Bergadã","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":78598,"journal":{"name":"Revista argentina de endocrinologia y metabolismo","volume":"16 3","pages":"81-3"},"PeriodicalIF":0.0,"publicationDate":"1970-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16606591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}