American Journal of Biomedical and Life Sciences最新文献_第4页

Epidemiological Profile of Urinary Tract Infections Observed at the Institut Pasteur in Bangui, Central African Republic 中非共和国班吉巴斯德研究所尿路感染的流行病学概况

American Journal of Biomedical and Life Sciences Pub Date : 2022-01-01 DOI: 10.11648/j.ajbls.20221002.15

Alain Farra, Sylvanus Mogalama, Christian Diamant Mossoro-Kpinde, Gilles Ngaya, Jean Robert Mbecko, Hugues Sanke-Waïgana, A. Manirakiza

引用次数: 0

Study of the Microbiological Quality of Groundwater in the Don Bosco District of Mimboman in the City of Yaoundé, Cameroon 喀麦隆yaound<s:1>市Mimboman Don Bosco区地下水微生物质量研究

American Journal of Biomedical and Life Sciences Pub Date : 2022-01-01 DOI: 10.11648/j.ajbls.20221001.11

Bernadette Fokou Bomgning, Cédric Gueguim, Aurelle Yondo, Maeva Ngouoyou, A. Ragon, H. Gonsu Kamga

引用次数: 0

Sanitary Status and Bio-monitoring of Surface Water Quality in the City of Maroua (Far North, Cameroon) 喀麦隆北部马鲁阿市地表水水质卫生状况及生物监测

American Journal of Biomedical and Life Sciences Pub Date : 2022-01-01 DOI: 10.11648/j.ajbls.20221003.13

Tonmeu Douyong Chimene Sandrine, Nguepidjo Gilbert, Kapso Tchouankep Mireille, Ewodo Mboudou Guillaume

引用次数: 0

The Analysis of Clinical Biological and Pathological Features in Papillary Thyroid Carcinoma 甲状腺乳头状癌临床生物学及病理特征分析

American Journal of Biomedical and Life Sciences Pub Date : 2021-11-17 DOI: 10.11648/J.AJBLS.20210905.21

Ying Li, Yimin Su, Rongqin Dai, F. Zhou, Chao Shen, Zhongzhou Su, Guiqiang Yang

{"title":"The Analysis of Clinical Biological and Pathological Features in Papillary Thyroid Carcinoma","authors":"Ying Li, Yimin Su, Rongqin Dai, F. Zhou, Chao Shen, Zhongzhou Su, Guiqiang Yang","doi":"10.11648/J.AJBLS.20210905.21","DOIUrl":"https://doi.org/10.11648/J.AJBLS.20210905.21","url":null,"abstract":"Papillary thyroid carcinoma (PTC) is one of the most common thyroid tumors in clinic. The incidence of papillary thyroid carcinoma is increasing year by year, especially in Cangzhou area, which brings great physical and mental pain to patients. Object: The understanding is further strengthened, and the level of diagnosis and treatment is improved, through the analysis of the biological and clinicopathological characteristics of papillary thyroid carcinoma. Method: Hospitalized cases with papillary thyroid carcinoma were collectedand biological and pathological characteristics were analyzed. Result: Among 110 cases of papillary thyroid carcinoma, 11 cases were male (10%), 99 cases were female (90%). There was no significant difference in invasiveness, lymph node metastasis, proportion of papillary microcarcinoma, number of lesions and involvement of glandular lobe, which were divided into groups according to different ages and different genders, (P>0.05). The average age of 46 cases with invasion was younger than that without invasion (P<0.001). There was less invasion and lymph node metastasis in papillary microcarcinoma (P<0.001). 16 cases of Hashimoto's thyroiditis were female, the average age of onset was higher, the difference was statistically significant (P<0.001) and TSH level was also higher than the patients without Hashimoto's thyroiditis (P<0.05). Conclusion: There was no significant difference in the clinicopathological characteristics of papillary thyroid carcinoma in different age groups and gender groups, but in the invasive study, the average age of patients with invasion was lower. Patients with papillary microcarcinoma are less likely to have invasion and lymph node metastasis. TSH levels are generally high in patients with Hashimoto's thyroiditis.","PeriodicalId":7857,"journal":{"name":"American Journal of Biomedical and Life Sciences","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85486723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Deep Learning Technology-based Model to Identify Benign and Pro-B Acute Lymphoblastic Leukemia (ALL): Xception + LIME 基于深度学习技术的急性淋巴细胞白血病(ALL)识别模型:例外+ LIME

American Journal of Biomedical and Life Sciences Pub Date : 2021-10-30 DOI: 10.11648/J.AJBLS.20210905.19

Nayeon Kim

{"title":"Deep Learning Technology-based Model to Identify Benign and Pro-B Acute Lymphoblastic Leukemia (ALL): Xception + LIME","authors":"Nayeon Kim","doi":"10.11648/J.AJBLS.20210905.19","DOIUrl":"https://doi.org/10.11648/J.AJBLS.20210905.19","url":null,"abstract":"Leukemia is a type of cancer that occurs when abnormal blood cells take place in the bone marrow. Leukemia can either be acute (fastly growing) or chronic (slowly growing) and it is considered as one of the most commonly diagnosed cancers for children younger than the age of 15 or adults older than the age of 55. Leukemia can be diagnosed through various types of tests and depending on the aggressiveness of the disease, the treatment may differ. To provide a low-cost, time-efficient solution, this study employs the deep learning technique to train the Xception, VGG16, VGG19, and MobileNet models to optimize the accuracy of medical image detection. Through medical imaging, the trained model is able to detect anomalies in the dataset and identify whether the given data is a benign acute lymphoblastic leukemia (ALL) or a Pro-B ALL. Overall, this VGG16 showed the most optimal performance in terms of accuracy and precision, producing a 98.5% accuracy in detecting abnormal regions from the dataset. This study also further used XAI technique and a deep convolutional neural network to visualize the results of anomalies. As a result, this paper concluded that both deep learning and machine learning techniques are yet to replace human resources and intelligence as the heatmap and the LIME portrayal identified different regions as abnormal parts, therefore proving the inconsistency of deep learning technology.","PeriodicalId":7857,"journal":{"name":"American Journal of Biomedical and Life Sciences","volume":"82 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73031467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Co-relation Between Perinatal Asphyxia with Hypoxic Ischemic Encephalopathy (PNA with HIE) and Blood Sugar Level 围生期缺氧缺血性脑病窒息与血糖水平的关系

American Journal of Biomedical and Life Sciences Pub Date : 2021-10-28 DOI: 10.11648/J.AJBLS.20210905.17

A. Hakim, Mahmuder Rahman, M. Begum

{"title":"Co-relation Between Perinatal Asphyxia with Hypoxic Ischemic Encephalopathy (PNA with HIE) and Blood Sugar Level","authors":"A. Hakim, Mahmuder Rahman, M. Begum","doi":"10.11648/J.AJBLS.20210905.17","DOIUrl":"https://doi.org/10.11648/J.AJBLS.20210905.17","url":null,"abstract":"Introduction: Perinatal asphyxia is one of the most common primary causes of mortality and morbidity among neonates. Perinatal asphyxia will result in neonatal hypoxia and tissue/organ injury. Objective: The aim of this study was to observe the Co-relation between Perinatal asphyxia with Hypoxic Ischemic Encephalopathy (PNA with HIE) and Blood sugar level. Methodology: This is a descriptive cross-sectional case study where a total of 182 neonates were admitted to the hospital with the problem of Perinatal asphyxia with Hypoxic Ischemic Encephalopathy and with some other associated problem. Result: Among the cases, 114 (62.6%) were Boys and 68 (37.45%) Girls. The mean age was 29.72 ± 78.42, Weight 2.77 ± .60, RBS 6.57 ± 7.38. Among the asphyxiated neonates blood sugar levels in arterial cord blood were significantly lower and had a negative (r=−0.195, P<0.01) correlation with the severity of birth asphyxia and different stages of HIE. Conclusion: Perinatal asphyxia can result in neonatal hypoxia and tissue/organ injury. A variety of maternal, obstetric, and neonatal conditions predispose the fetus and newborn to asphyxia, which can occur before, during, or after birth From our result, we can conclude that the relationship between Perinatal asphyxia and blood sugar level is significantly lower and negative.","PeriodicalId":7857,"journal":{"name":"American Journal of Biomedical and Life Sciences","volume":"74 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86444608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Effectiveness and Tolerability of the ASAQ versus AL Association in Children 6-59 Months for the Treatment of Uncomplicated P. falciparum Malaria in Massakory (Chad) 乍得Massakory地区6-59月龄儿童无并发症恶性疟原虫ASAQ与AL相关性的疗效和耐受性比较

American Journal of Biomedical and Life Sciences Pub Date : 2021-10-21 DOI: 10.11648/J.AJBLS.20210905.16

Mahamat Moussa Hassane Taïsso, I. Souleymane, Hamit Mahamat Alio, Mahamat Saleh Issakha Diar, Djiddi Ali Sougoudi, D. Mbanga, P. Ringwald, D. Honoré, Issa Ali Haggar, Hassoumi Manah, Hassan Ahmat Mihedi, N’garadoum Olivier, D. Koffi, O. Touré, D. Joseph

{"title":"Effectiveness and Tolerability of the ASAQ versus AL Association in Children 6-59 Months for the Treatment of Uncomplicated P. falciparum Malaria in Massakory (Chad)","authors":"Mahamat Moussa Hassane Taïsso, I. Souleymane, Hamit Mahamat Alio, Mahamat Saleh Issakha Diar, Djiddi Ali Sougoudi, D. Mbanga, P. Ringwald, D. Honoré, Issa Ali Haggar, Hassoumi Manah, Hassan Ahmat Mihedi, N’garadoum Olivier, D. Koffi, O. Touré, D. Joseph","doi":"10.11648/J.AJBLS.20210905.16","DOIUrl":"https://doi.org/10.11648/J.AJBLS.20210905.16","url":null,"abstract":"Background and Objective: Artemisinin-based combination therapies are the first-line antimalarial drugs used to treat uncomplicated Plasmodium falciparum malaria in many endemic countries worldwide. This study was conducted to assess the efficacy and tolerability of two fixed-dose formulations of artesunate-amodiaquine and artemether-lumefantrine for the treatment of Plasmodium falciparum malaria in Chad. Methodology and Results: A two-arm single cohort study was conducted assessing the efficacy artesunate-amodiaquine and artemether-lumefantrine for the treatment of children with uncomplicated falciparum malaria. This study was carried out from December 14, 2019 to March 14, 2020 at the Massakory I Health Center in Chad. Primary efficacy endpoint was day 28, parasitological cure rate. Secondary endpoints were parasite and fever clearance times and tolerability. A total of 113 patients were included, including 56 in the artesunate-amodiaquine arm and 57 in the artemether-lumefantrine arm. In intention to treat these patients, the Adequate Clinical and Parasitological Response on day 28 were 100% for the two groups. No early treatment failure was observed. The drugs were well tolerated and no serious adverse events were noted. Conclusion: Both forms of Artemisinin-based combination therapy were still effective and safe in the treatment of uncomplicated P. falciparum malaria in Chad. Further studies are warranted in different regions of Chad for monitoring of drug resistance.","PeriodicalId":7857,"journal":{"name":"American Journal of Biomedical and Life Sciences","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75062618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Growth Delay in Children: Experience of the Department of Metabolic and Endocrine Diseases at the Children's Hospital of Rabat 儿童生长迟缓:拉巴特儿童医院代谢和内分泌疾病科的经验

American Journal of Biomedical and Life Sciences Pub Date : 2021-10-19 DOI: 10.11648/J.AJBLS.20210905.15

Touzani Asmae, Tahri Joutei Abderrafie, Joutei Abderrafie, Dami Abdellah, Balouch Lhousaine, Kriouile Yamna, Z. Imane, Gaouzi Ahmed

{"title":"Growth Delay in Children: Experience of the Department of Metabolic and Endocrine Diseases at the Children's Hospital of Rabat","authors":"Touzani Asmae, Tahri Joutei Abderrafie, Joutei Abderrafie, Dami Abdellah, Balouch Lhousaine, Kriouile Yamna, Z. Imane, Gaouzi Ahmed","doi":"10.11648/J.AJBLS.20210905.15","DOIUrl":"https://doi.org/10.11648/J.AJBLS.20210905.15","url":null,"abstract":"Objective: The aim of our study is to describe the epidemiological, clinical and biological aspects of staturo-ponderal delay and to deduce the main etiologies. Material and Methods: the study was carried out on 141 patients (78 boys and 63 girls). Patients ranged in age from 9 months to 17 years (mean: 9 years 1 month) with a statural delay that varied from -2DS to -5DS (mean: -2.5DS). Results: Analysis of the data showed a frequency of 13.5% of patients with severe growth retardation, 35% of whom had a growth hormone deficiency. The hormonal assessment showed a GH deficiency in 43% of patients with a greater difference in chronological age and bone age (2.5 years) than in non-deficient patients (2 years). Among them, 51% of patients have an elevated TSH. Magnetic resonance imaging performed in 37 cases was in favor of a pituitary anomaly in 12% of cases, including interruption of the pituitary stem (4% of cases), hypoplasia (3% of cases), an adenoma (1% of cases) and an empty sella turcica in 4% of cases. Conclusion: Severe central growth retardation is common. Systematic monitoring and follow-up of growth is essential in children, as is vaccination, in order to identify and manage early any causal pathology that may disrupt the child's growth.","PeriodicalId":7857,"journal":{"name":"American Journal of Biomedical and Life Sciences","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73890308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of a CMAM Intervention on Demand for Other Primary Health Care Services in Katsina State, Nigeria cmm干预对尼日利亚卡齐纳州其他初级卫生保健服务需求的影响

American Journal of Biomedical and Life Sciences Pub Date : 2021-10-19 DOI: 10.11648/J.AJBLS.20210905.14

Azeez Afebu Oseni, Wale Falade

{"title":"Impact of a CMAM Intervention on Demand for Other Primary Health Care Services in Katsina State, Nigeria","authors":"Azeez Afebu Oseni, Wale Falade","doi":"10.11648/J.AJBLS.20210905.14","DOIUrl":"https://doi.org/10.11648/J.AJBLS.20210905.14","url":null,"abstract":"Malnutrition in both acute and chronic forms is a global issue responsible for as much as 50% of infant mortality worldwide. Acute malnutrition exists as both moderate and severe forms depending on factors such as access to nutritious meals and maternal care practices. Moderate Acute Malnutrition (MAM) can be easily treated and has lesser mortality impacts compared to Severe Acute Malnutrition (SAM). Community Management of Acute Malnutrition (CMAM) is a community-based approach to addressing SAM and MAM. In this study, the impact of a donor funded CMAM intervention delivered through primary healthcare (PHC) facilities in Katsina state, Nigeria is measured. Prior to this study, there was low utilization of these facilities due to the several factors such as transportation and communication problems, traditional conservatism, poor quality of services, and low literacy rates. A randomised sampling method was used to select and compare 5 CMAM and 5 non-CMAM facilities across the state. A test for significance for two independent groups (CMAM supported and non-CMAM supported sites) was also conducted for different categories of admissions such as antenatal care (ANC), outpatient department (OPD) and routine immunization (RI). From the result, it is concluded that the CMAM intervention increased the rate of patient access and use of PHCs within the state. The test of significance also shows significant differences between the admissions for OPD, ANC, and RI when compared to non-CMAM sites.","PeriodicalId":7857,"journal":{"name":"American Journal of Biomedical and Life Sciences","volume":"58 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84158626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Vascular Endothelial Growth Factor’s Expression in Gastric Cancer and Progress in Prognostic Research 血管内皮生长因子在胃癌中的表达及预后研究进展

American Journal of Biomedical and Life Sciences Pub Date : 2021-09-30 DOI: 10.11648/J.AJBLS.20210905.13

Li Hongyan, Zhan Shuli, Hou Jianzhang

{"title":"The Vascular Endothelial Growth Factor’s Expression in Gastric Cancer and Progress in Prognostic Research","authors":"Li Hongyan, Zhan Shuli, Hou Jianzhang","doi":"10.11648/J.AJBLS.20210905.13","DOIUrl":"https://doi.org/10.11648/J.AJBLS.20210905.13","url":null,"abstract":"Gastric cancer (GC) is not only one of the common gastrointestinal malignancies in clinic, but also the most common cancer in the world. In recent years, its morbidity has increased. The global morbidity and mortality of gastric cancer rank fifth among all malignancies. The morbidity and mortality of gastric cancer in our country ranks second among malignant tumors, which is twice as high as the world average. In rural, the number is 1.6 times of in urban. The early diagnosis of most gastric cancers is rare in majority of patients, and most of them are in intermediate or advanced stage when they are in treatment. The proportion of radical surgery is not high, and it is easy to relapse and metastasize. The 5-year survival rate is about 40%, and the treatment effect is poor, which is severely harmful to people’s health. Although the pathogenesis of gastric cancer is related to many factors, the nosogenesis is vague. The occurrence of tumors is closely related to the formation of new blood vessels. New blood vessels are the internal conditions for tumor cell proliferation and metastasis. The factors that promoting angiogenesis include more than 10 kinds of fibroblast growth factors (FGFs) and vascular endothelial growth factors (VEGF), among which VEGF is the most important regulator that promotes angiogenesis. By promoting the mitosis of vascular endothelial cells, it forms an essential matrix for the growth of vascular endothelial cells, plays a crucial regulatory role in the process of tumor angiogenesis, and participates in the occurrence and development of a variety of tumor cells. This article summarizes the research progress on the vascular endothelial growth factor’s expression in gastric cancer and prognostics follows.","PeriodicalId":7857,"journal":{"name":"American Journal of Biomedical and Life Sciences","volume":"65 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76312230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0