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Cytotoxic Activity of Parmelia perlata Extracts against Artemia Salina 帕尔玛提取物对盐蒿的细胞毒活性研究
Journal of experimental medical sciences Pub Date : 2016-08-23 DOI: 10.19071/jes.2016.v7.3084
M. Mayilsamy, K. Geetharamanan
{"title":"Cytotoxic Activity of Parmelia perlata Extracts against Artemia Salina","authors":"M. Mayilsamy, K. Geetharamanan","doi":"10.19071/jes.2016.v7.3084","DOIUrl":"https://doi.org/10.19071/jes.2016.v7.3084","url":null,"abstract":"The brine shrimp lethality bio assay represents a rapid, inexpensive and simple bioassay for testing plant extracts bioactivity which in most cases correlates reasonably well with cytotoxic and antitumor properties. The assay is considered to be a very useful tool for preliminary assessment of toxicity. In the present study the lichen Parmelia perlata was extracted with solvents of varying polarity such as hexane, ethyl acetate, acetone and methanol and tested for hatch inhibition of cysts of Artemia salina and cytotoxic activities against Artemia salina naupilii. The highest cytotoxic potential among all the plant extracts tested was explored from the hexane extract of P. perlata which showed 100% brine shrimp mortality at 100ppm. The least activity among all the plant extracts was found in the methanol extract of  P. perlata.","PeriodicalId":78355,"journal":{"name":"Journal of experimental medical sciences","volume":"16 1","pages":"36-39"},"PeriodicalIF":0.0,"publicationDate":"2016-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83451183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microalgae-based biodiesel production: Current and future scenario 基于微藻的生物柴油生产:当前和未来的情景
Journal of experimental medical sciences Pub Date : 2016-07-08 DOI: 10.25081/JES.2016.V7.3027
S. Sahay, V. Braganza
{"title":"Microalgae-based biodiesel production: Current and future scenario","authors":"S. Sahay, V. Braganza","doi":"10.25081/JES.2016.V7.3027","DOIUrl":"https://doi.org/10.25081/JES.2016.V7.3027","url":null,"abstract":"Microalgae have a clear potential to be used as a source for the production of biofuel. In order to utilize microalgae for this purpose, the most common systems for cultivating and harvesting them are investigated in the previous years. Since there are many species of microalgae with varying lipid accumulating characteristics, a diversity of options for the production of microalgae based energy have been analyzed. Subsequently, the energy inputs and conditions needed for growing and harvesting the microalgae and its oil production potentials are examined. This concludes with a formulation of complete concept for producing a renewable energy carrier from microalgae, which will be used for in-depth analysis.","PeriodicalId":78355,"journal":{"name":"Journal of experimental medical sciences","volume":"33 1","pages":"31-35"},"PeriodicalIF":0.0,"publicationDate":"2016-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79177558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
In vitro antifungal activity of Turbinaria conoides collected from Mandapam coast, Tamilnadu, India 印度泰米尔纳德邦曼达帕姆海岸产conoides的体外抑菌活性研究
Journal of experimental medical sciences Pub Date : 2016-05-28 DOI: 10.19071/JES.2016.V7.3057
A. Shibu, S. Dhanam
{"title":"In vitro antifungal activity of Turbinaria conoides collected from Mandapam coast, Tamilnadu, India","authors":"A. Shibu, S. Dhanam","doi":"10.19071/JES.2016.V7.3057","DOIUrl":"https://doi.org/10.19071/JES.2016.V7.3057","url":null,"abstract":"ABSTRACT Marine macroalgae have been used as medicines or drug sources for a great many years, stretching back to the era of folk medicines. Algae have been extensively used in the traditional medicines of maritime nations for treatment of goitre, cancer, hypertension, cough and other diseases. The present work was carried out to find out the antifungal activity of the seaweed Turbinaria conoides collected from Mandapam coastal regions of Tamilnadu. The extracts were tested against Candida albicans , Candida parapsilopsis , Fusarium sp, Aspergillus flavus , Asergillus fumigatus . The hexane, chloroform and ethanolic extracts showed a well profound inhibitory activity against Candida albicans and Candida parapsilopsis. No inhibitory activity was found at Fusarium sp , Aspergillus flavus , Asergillus fumigates under chloroform and ethanolic extracts. Key words: Medicine, antifungal, cancer, Candida albicans, diseases.","PeriodicalId":78355,"journal":{"name":"Journal of experimental medical sciences","volume":"1 1","pages":"27-30"},"PeriodicalIF":0.0,"publicationDate":"2016-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79575794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Ovicidal, oviposition deterrent and larvicidal response of Anopheles stephensi Liston, 1901 to Lobophora variegata Lamouroux, 1817 from Tuticorin coast, Gulf of Mannar, India 印度马纳尔湾Tuticorin海岸斯氏按蚊1901年对1817年斑蝽的杀卵、阻卵和杀幼虫反应
Journal of experimental medical sciences Pub Date : 2016-05-14 DOI: 10.19071/JES.2016.V7.2976
T. Veni, T. Pushpanathan, J. Mohanraj
{"title":"Ovicidal, oviposition deterrent and larvicidal response of Anopheles stephensi Liston, 1901 to Lobophora variegata Lamouroux, 1817 from Tuticorin coast, Gulf of Mannar, India","authors":"T. Veni, T. Pushpanathan, J. Mohanraj","doi":"10.19071/JES.2016.V7.2976","DOIUrl":"https://doi.org/10.19071/JES.2016.V7.2976","url":null,"abstract":"The objective of the present study was to investigate the mosquito ovicidal, oviposition deterrent and larvicidal efficacy of hexane, benzene, chloroform, ethyl acetate and methanol extracts of, Lobophora variegata against malarial vector Anopheles stephensi . Among the five extract tested, the methanol extract was notable, which attained the 100 percent mortality at the concentration of 200.0 ppm and the hatchability rate ranged from 71.3 to 36.3 percent. In laboratory oviposition deterrent test, the extract of L. variegata greatly reduced the number of eggs deposited by gravid An. stephensi . The maximum and significant diminished fecundity in An. stephensi was observed with methanol extract which caused 76.15­–97.69% effective deterrence. Larvicidal response of An. stephensi was more susceptible in methanol extract. The LC 50 ­value of methanol extract was 61.63 ppm and the Chi-square value were significant at p <0.05 level. It is concluded, that the extract of  L. variegata could be used in control of malarial vector An. stephensi .","PeriodicalId":78355,"journal":{"name":"Journal of experimental medical sciences","volume":"9 1","pages":"20-26"},"PeriodicalIF":0.0,"publicationDate":"2016-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76494729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A QUANTITATIVE ANALYSIS OF SPATIAL ORGANIZATION OF THE URBAN CENTRES IN KASHMIR VALLEY – A GIS BASED STUDY USING PRIMACY INDEX, RANK SIZE RULE AND NEAREST NEIGHBOUR INDEX 克什米尔山谷城市中心空间组织的定量分析——基于地理信息系统的首要指数、等级大小规则和最近邻指数研究
Journal of experimental medical sciences Pub Date : 2016-05-05 DOI: 10.19071/JES.2016.V7.2992
Z. Fayaz, M. S. Bhat
{"title":"A QUANTITATIVE ANALYSIS OF SPATIAL ORGANIZATION OF THE URBAN CENTRES IN KASHMIR VALLEY – A GIS BASED STUDY USING PRIMACY INDEX, RANK SIZE RULE AND NEAREST NEIGHBOUR INDEX","authors":"Z. Fayaz, M. S. Bhat","doi":"10.19071/JES.2016.V7.2992","DOIUrl":"https://doi.org/10.19071/JES.2016.V7.2992","url":null,"abstract":"Kashmir valley located in the heart of huge mountain ranges has experienced urbanization over time and space and is presently home to 46 urban centres located in different parts of the region. The present study aims at analyzing the spatial distribution pattern and spacing of the towns using geographic information system (GIS) and the rarely used quantitative technique of near neighbour analysis. Kashmir Valley is characterized by the strong urban primacy of Srinagar city which is 8 times larger than the population of Anantnag town, 16 times larger than the population of Baramulla and 17 times larger than the population of Sopore town. The application of Rank Size Rule reveals that the relationship among the urban centres in Kashmir Valley is not in conformity with it. The study reveals that the urban settlements in Kashmir Valley are randomly distributed and do not exhibit any specific distribution pattern. The range of spacing varies from 33 kms to 3 kms. The average distance of spacing between the settlements is 9 kms, while the hypothetical mean nearest neighbour distance is 18 kms. The inferences of the analysis could be used as inputs for the spatial planning process and for balanced urban development.","PeriodicalId":78355,"journal":{"name":"Journal of experimental medical sciences","volume":"168 1","pages":"11-19"},"PeriodicalIF":0.0,"publicationDate":"2016-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73192910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
EFFECT OF BIO-STIMULATORS ON PRODUCTION OF COWPEA SEED FOR FOOD SECURITY AND WEALTH CREATION IN JUJA, KENYA 生物刺激器对肯尼亚朱贾豇豆种子生产的粮食安全和财富创造的影响
Journal of experimental medical sciences Pub Date : 2016-04-15 DOI: 10.19071/jes.2016.v7.2960
Judith Oyoo Ilukol
{"title":"EFFECT OF BIO-STIMULATORS ON PRODUCTION OF COWPEA SEED FOR FOOD SECURITY AND WEALTH CREATION IN JUJA, KENYA","authors":"Judith Oyoo Ilukol","doi":"10.19071/jes.2016.v7.2960","DOIUrl":"https://doi.org/10.19071/jes.2016.v7.2960","url":null,"abstract":"A study was done to evaluate the effect of bio-stimulators on seed production of cowpea crop in Juja, Kenya during short rains season 2014-15. Bio-stimulators are plant and animal derived substances that trigger plant processes when applied to the plants at very low concentrations. They contain amino acids, low molecular weight polypeptides, vitamins, enzymes, hormones, sugars, betaines and antioxidants. Drought causes slow rate of the majority of plant growth and development processes leading to discontinuation of cell growth, stomatal closures, increased abscisic acid and proline, drop in cytokinins levels, reduced protein synthesis and reduced activity of nitrate reductase leading to retarded growth and plant senescence. In reducing the impact of the water stress therefore, cytokinins in bio-stimulators promote growth and slow down plant senescence. Parameters investigated were germination rate, days to flowering and pod formation, number of seeds per pod, length of pods, total number of pods and weight of seeds. Results on the effect of bio-stimulators on cowpea seed production are discussed.","PeriodicalId":78355,"journal":{"name":"Journal of experimental medical sciences","volume":"21 1","pages":"7-10"},"PeriodicalIF":0.0,"publicationDate":"2016-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90804620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SILVER NANOPARTICLES FOR ENHANCEMENT OF ACCUMULATION OF CAPSAICIN IN SUSPENSION CULTURE OF CAPSICUM SP. 纳米银粒子对辣椒悬浮培养中辣椒素积累的促进作用。
Journal of experimental medical sciences Pub Date : 2016-03-29 DOI: 10.19071/JES.2016.V7.3001
P. Bhat, Akash P. Bhat
{"title":"SILVER NANOPARTICLES FOR ENHANCEMENT OF ACCUMULATION OF CAPSAICIN IN SUSPENSION CULTURE OF CAPSICUM SP.","authors":"P. Bhat, Akash P. Bhat","doi":"10.19071/JES.2016.V7.3001","DOIUrl":"https://doi.org/10.19071/JES.2016.V7.3001","url":null,"abstract":"Secondary metabolites can be very important chemicals for the development of plants. The secondary metabolite in this study is obtained from capsicum . Capsaicin is industrially very important due to its wide use range. Thestudy involved is the use of silver nanoparticles for elicitation of levels of capsaicin. Mediums with different hormonal combinations were prepared and growth was studied using qualitative analysis using iodine fumes, Gibbs Reagent and quantitative analysisusing Phosphomolybdic Acid Method and Folin- Ciocalteu method. This brings down a conclusion that the nanoparticles acted as an elicitor and brought about capsaicin increase effectively. Extraction of the metabolite from these natural sources also prove easier and the product can be obtained in a much purified form.","PeriodicalId":78355,"journal":{"name":"Journal of experimental medical sciences","volume":"16 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2016-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87518681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 18
Isolation of mosquito larvicidal molecule form the leaves of Clausena anista 从黄花叶中分离灭蚊幼虫分子
Journal of experimental medical sciences Pub Date : 2015-12-23 DOI: 10.19071/JES.2015.V6.2927
M. Jayaraman, A. Senthilkumar, G. A. Raj, V. Venkatesalu
{"title":"Isolation of mosquito larvicidal molecule form the leaves of Clausena anista","authors":"M. Jayaraman, A. Senthilkumar, G. A. Raj, V. Venkatesalu","doi":"10.19071/JES.2015.V6.2927","DOIUrl":"https://doi.org/10.19071/JES.2015.V6.2927","url":null,"abstract":"The vector-borne diseases caused by mosquitoes are one of the major health problems in many countries especially in tropical and sub-tropical countries. The resistance of mosquitoes to synthetic chemicals and environmental toxicity created by the chemicals raised the demand for finding of alternate natural molecules that control mosquito. In the present study, the compound 1, 2-Benzenedicarboxylic acid, mono (2-ethylhexyl) ester was isolated from the ethyl acetate extract of leaves of Clausena anisata and it was identified by various spectral studies. The larvicidal potential of the isolated compound was evaluated against early 4 th instar larvae of Culex quinquefasciatus , Aedes aegypti and Anopheles stephensi. The compound exhibited 100% larval mortality against A. aegypti and A. stephensi at 40 ppm with LC 50 values of 8.944 and 9.230 ppm respectively. The molecule also showed the LC 50 value of 12.067 ppm against C . quinquefasciatus. The molecule isolated from C. anisata can be better explored for the control of mosquito population after toxicological evaluation.","PeriodicalId":78355,"journal":{"name":"Journal of experimental medical sciences","volume":"1 1","pages":"12-16"},"PeriodicalIF":0.0,"publicationDate":"2015-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91221657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Vertical Electrical Soundings for Locating Groundwater Potential Zones in Osmania University Campus, Hyderabad, Telangana State, India 印度特伦甘纳邦海得拉巴奥斯马尼亚大学校园地下水潜势区的垂直电测深
Journal of experimental medical sciences Pub Date : 2015-11-18 DOI: 10.19071/JES.2015.V6.2844
D. V. Kumar, G. Ramadass
{"title":"Vertical Electrical Soundings for Locating Groundwater Potential Zones in Osmania University Campus, Hyderabad, Telangana State, India","authors":"D. V. Kumar, G. Ramadass","doi":"10.19071/JES.2015.V6.2844","DOIUrl":"https://doi.org/10.19071/JES.2015.V6.2844","url":null,"abstract":"Based on the resistivity investigations Osmania University Campus, precisely depth and  resistivity of subsurface layers were computed, Various geoelectric sections along different profiels (I to VIII) was obtained and analyzed. The study area is showing four layered geoelectrical sections, the top soil layer of variable resisitivity  value between  11.2 to 599 Ωm, whose maximum thickness is 0.75 to 4.45 m.  The highly weathered second  layer resistivity value varing from1.72 to 1800 Ωm.  And thickness is 0.12 to 36.6m.  The third fractured layer indicated by resistivity value 16.3 to 46074 Ωm and thickness  is 4.9 to 87.4 m.  The basement that is associated with hard rock and very high resistivities ranging to infinity. The low restivity with thick overbuden and fractured bed rock constitute the aquifer units and the series of  basementt undulations identified from the geolelectrical sections  are potential points for groundwater  locations.","PeriodicalId":78355,"journal":{"name":"Journal of experimental medical sciences","volume":"8 1","pages":"1-11"},"PeriodicalIF":0.0,"publicationDate":"2015-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78485339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Antihepatotoxic potential of Citrullus colocynthis root extract, fractions and isolated compounds 瓜蒌根提取物、组分及分离化合物的抗肝毒性研究
Journal of experimental medical sciences Pub Date : 2013-04-15 DOI: 10.15415/jptrm.2014.22009
A. Mukerjee, S. Mishra, S. Saraf
{"title":"Antihepatotoxic potential of Citrullus colocynthis root extract, fractions and isolated compounds","authors":"A. Mukerjee, S. Mishra, S. Saraf","doi":"10.15415/jptrm.2014.22009","DOIUrl":"https://doi.org/10.15415/jptrm.2014.22009","url":null,"abstract":"Medicinal plants are considered to be effective and safe alternative treatment for liver toxicity. The article reveals the hepatoprotective activity of the ethanolic extract of the roots of the Citrullus colocynthis commonly known as INDRYAN using carbon tetrachloride (CCl 4 ) experimental model in albino rats. After receiving significant protection of Ethanolic extract on liver the extract further undergone fractionation into three fractions & the activity was localized in the toluene fraction. These on purification led to the isolation of two pure compounds which were identified as - Cucurbitacin B(1) and Colocynthin (2). The pure compound shows reduction in enzymatic level viz. (SGOT 68.09%, SGPT 63.64%, ALP 76.81%, BL 68.22%) and (SGOT 71.28%, SGPT 65.24%, ALP 80.68%, BL 54.92%) at 50 mg/ kg dose respectively whereas drug Silymarin showed reduction as (SGOT 79.73%, SGPT 74.26%, ALP 87.88%,BL 82.75% ) at 25 mg/kg dose level. On comparing the obtained data it was observed that the roots of C. colocynthis Sch. exhibited significantly better hepatoprotective activity, thus justifying the traditional claims.","PeriodicalId":78355,"journal":{"name":"Journal of experimental medical sciences","volume":"72 1","pages":"43-45"},"PeriodicalIF":0.0,"publicationDate":"2013-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86581106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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