{"title":"Medical-social intervention in a 70-year-old Swedish population. A general presentation of methodological experience.","authors":"B G Eriksson, D Mellström, A Svanborg","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The possibilities of improving physical, mental and social functioning or retarding the development of handicap and reducing the need for medical and social services were investigated in an interdisciplinary intervention study in a representative population sample of 1206 70-year-olds. The assessments concerned cognitive function and mental health, earlier and current social interaction and living conditions, state of health including dental status, muscular strength and performance, pulmonary and cardiovascular function, bone mineral content, ADL and dietary habits. The intervention (response rate 76.8%) concerned social, psychological, environmental and medical aspects in 400 and medical aspects only in 406 probands. 400 register controls were sampled for comparison. The intervention period was 2 years, and a follow-up study will be performed at the age of 75. The interventions were guided by the life-style and the activity hypotheses within the resource perspective to promote everyday activities. The study allows comparisons with two previous 70-year-old cohorts investigated with similar methods in Gothenburg.</p>","PeriodicalId":77838,"journal":{"name":"Comprehensive gerontology. Section C, Interdisciplinary topics","volume":"1 ","pages":"49-56"},"PeriodicalIF":0.0,"publicationDate":"1987-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14107243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ageing in the hypothalamo-neurohypophysial-renal system.","authors":"I Davies","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Ageing is characterised by a failure in the maintenance of the internal environment (homeostasis) which is regulated by the hypothalamic neuroendocrine system. Of the many systems that undergo age-related degeneration is the control of water metabolism which leads to a variety of complications in the elderly. The magnocellular neurons of the hypothalamus produce the peptide anti-diuretic hormone (vasopressin) which acts on the kidney regulating water loss in the urine. This physiological axis lends itself to both fundamental studies of the cellular and molecular biology of ageing, and to studies of age-related alterations in the functional ability of elderly people. This review summarises some of the recent research into age-related changes in this system. The morphological and functional changes in the hypothalamus, neurohypophysis and kidney are described for the various species examined and the results discussed in terms of ageing in humans.</p>","PeriodicalId":77838,"journal":{"name":"Comprehensive gerontology. Section C, Interdisciplinary topics","volume":"1 ","pages":"12-23"},"PeriodicalIF":0.0,"publicationDate":"1987-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14461061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}