The International journal of pediatric nephrology最新文献

Short-term Outcomes of Pediatric Renal Transplantation in Nigeria; A Single-Center Experience : 尼日利亚儿童肾移植的短期疗效单中心体验:

The International journal of pediatric nephrology Pub Date : 2021-11-10 DOI: 10.22037/JPN.V9I4.35429

E. Anigilaje, O. Olatise, Maduadi Kextero, I. Martins

引用次数: 0

Evaluation of Acute Kidney Injury and its Risk Factors in Children Admitted with Diagnosis of Nephrotic Syndrome 诊断为肾病综合征的儿童急性肾损伤及其危险因素的评价

The International journal of pediatric nephrology Pub Date : 2021-11-10 DOI: 10.22037/JPN.V9I4.35143

A. Kumari, Lehar Sahai, S Kumar, R. Bhatnagar

{"title":"Evaluation of Acute Kidney Injury and its Risk Factors in Children Admitted with Diagnosis of Nephrotic Syndrome","authors":"A. Kumari, Lehar Sahai, S Kumar, R. Bhatnagar","doi":"10.22037/JPN.V9I4.35143","DOIUrl":"https://doi.org/10.22037/JPN.V9I4.35143","url":null,"abstract":"Abstract \u0000Background and Aim: Acute Kidney Injury (AKI) is an important complication of Nephrotic Syndrome (NS) associated with adverse outcome. The frequency of AKI has increased to almost double in the last decade. To determine the incidence of AKI, risk factors and its association with outcome in hospitalized children with NS. \u0000Methods – All children aged 1-18 years with diagnosis of NS from 01 November 2018 to 31 May 2020 were enrolled for the study. AKI was diagnosed using the KIDIGO 2012 guidelines and classified according to pediatric RIFLE definition. \u0000Results –The mean age of children in this cohort was 4.7± 2.8 years. Complications were observed in 67% cases only. Among all complications the most frequent complication was anemia (25%). The incidence of AKI in hospitalized children with NS was 18.6%. According to pRIFLE criteria of AKI; 11.6% of children met Stage 1 (risk) criteria, 4.6% met Stage 2 (injury) criteria and 2.3% met Stage 3 (failure) respectively. Among all NS children, 53% received nephrotoxic drugs during the hospital stay. On applying multivariate logistic regression analysis, only male gender, associated anemia and Vancomycin use in NS patients came out to be significant independent risk factor for acute kidney injury. \u0000Conclusions: AKI is more frequent in first episode of NS rather than in any type of relapses. Although, nephrotoxic drug and male gender are known independent risk factors for development of AKI, associated anemia is till yet not considered as independent risk factor for AKI in children with NS.","PeriodicalId":77809,"journal":{"name":"The International journal of pediatric nephrology","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80077289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sarcoma Botryoides of Bladder in an Infant 1例婴儿膀胱肉样肉瘤

The International journal of pediatric nephrology Pub Date : 2021-11-10 DOI: 10.22037/JPN.V9I4.35638

T. Babu, P. Balakrishnan, V. Sharmila

引用次数: 0

Proportion of urinary tract infection in neonatal sepsis 尿路感染在新生儿败血症中的比例

The International journal of pediatric nephrology Pub Date : 2021-11-10 DOI: 10.22037/JPN.V9I4.35709

Parvez Ahmed, M. Ashraf, S. Andrabi, Asma Wani, S. Bhat, N. Mir

{"title":"Proportion of urinary tract infection in neonatal sepsis","authors":"Parvez Ahmed, M. Ashraf, S. Andrabi, Asma Wani, S. Bhat, N. Mir","doi":"10.22037/JPN.V9I4.35709","DOIUrl":"https://doi.org/10.22037/JPN.V9I4.35709","url":null,"abstract":"Background: Urinary tract infection (UTI) in neonates might be associated with bacteremia and congenital anomalies of the kidney and urinary tract (CAKUT), that in complicated situations can lead to renal parenchymal scarring and chronic kidney disease. Aim: To determine occurrence of UTI in neonatal sepsis. Methods: This cross sectional study was conducted on 500 term, extramural hospitalized neonates, suspected to have infection underwent, a detailed history, physical examination and a comprehensive sepsis workup. The diagnosis of neonatal UTI was based, on positive urine culture, obtained by suprapubic aspiration (SPA). Results: Out of 500 neonates included in our study (324 boys and 176 girls), blood culture was positive in 84 (36.5%) neonates in early-onset sepsis group (n=230), while in late-onset sepsis group (n=270) blood culture was positive in130 (48.1%), p-value < 0.05. In both early-onset sepsis (EOS) and late-onset sepsis (LOS) groups, blood culture was found to be positive in a greater proportion of male (41.3%) than female (29.3%) patients, p-value <0.05. The most common organism isolated from blood and urine culture was Klebsiella, followed by E-coli. Urine culture was positive in 34 (6.8%) patients, among whom 29 (85%) culture-positive cases were from the LOS group, a p-value of <0.05. Conclusions: UTI is not uncommon among the hospitalized neonates, and UTI evaluation among septic neonates can prove beneficial for the prevention of long-term sequelae of neonatal UTI.","PeriodicalId":77809,"journal":{"name":"The International journal of pediatric nephrology","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79113583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of Potassium Citrate Solution in the Treatment of Renal Microlithiasis in Children 1 Month to 15 Years-old 枸橼酸钾溶液治疗1个月~ 15岁儿童肾小结石的疗效观察

The International journal of pediatric nephrology Pub Date : 2021-11-10 DOI: 10.22037/JPN.V9I4.34884

S. Mohajeri, Elham Emami, R. Choopani, A. Malekpour, Razieh-Sadat Mousavi

{"title":"Efficacy of Potassium Citrate Solution in the Treatment of Renal Microlithiasis in Children 1 Month to 15 Years-old","authors":"S. Mohajeri, Elham Emami, R. Choopani, A. Malekpour, Razieh-Sadat Mousavi","doi":"10.22037/JPN.V9I4.34884","DOIUrl":"https://doi.org/10.22037/JPN.V9I4.34884","url":null,"abstract":"Abstract \u0000Background and objective: The present research aims to determine efficacy of potassium citrate solution in the treatment of renal microlithiasis in children one month to 15 years old in Shahrekord Pediatric Nephrology Clinic. \u0000Methodology: In this clinical trial study, 60 children aged 1 month to 15 years referred to Shahrekord Pediatric Nephrology Clinic who had one or two (microlithiasis) less than 3 mm in ultrasound; They were included in the study by available sampling. Children were randomly divided into 2 groups receiving placebo (water) and receiving potassium citrate solution. After 3 months, the number and size of stones and the consequences of stones were recorded in both groups and analyzed using SPSS software and relevant statistical tests. \u0000Results: Out of 60 children studied, 34 were male (56.7%) and 26 were females (43.3%) with a mean age of 61.62 47 47.54 months. After 3 months of intervention, the mean number and size of stones in each group had a significant decrease (P <0.001) and this amount was lower in the group receiving potassium citrate than the group receiving placebo, but this difference was not statistically significant (<0.05). P). Also, the consequences of kidney stones in both groups were similar and there was no significant difference (P <0.05). \u0000Conclusion: The results of this study showed that potassium citrate solution has no effect on the treatment of one or two microlithiasis in children and in these patients the use of supportive therapy is still sufficient. \u0000Keywords: Kidney stones, Microlithiasis, Children, Potassium citrate","PeriodicalId":77809,"journal":{"name":"The International journal of pediatric nephrology","volume":"248 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76788265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bilateral Nephromegaly in a Child with Severe Iron-Deficiency Anemia 重度缺铁性贫血儿童双侧肾畸形1例

The International journal of pediatric nephrology Pub Date : 2021-11-08 DOI: 10.22037/JPN.VI.34772

D. Weizmann, D. Genest, C. Litalien, G. Benoît

引用次数: 0

Long-Term Outcome of Kidney Transplantation in Children According to Type of Transplantation in Mashhad, Iran: 伊朗马什哈德不同移植类型儿童肾移植的远期疗效

The International journal of pediatric nephrology Pub Date : 2021-11-08 DOI: 10.22037/JPN.VI.34617

Y. Ravanshad, A. Ghodsi, Mohaddeseh Golsorkhi, A. Azarfar, S. Ravanshad, Samaneh Heidarzadeh, Hamidreza Ghodsi, Aida Tasbandi

{"title":"Long-Term Outcome of Kidney Transplantation in Children According to Type of Transplantation in Mashhad, Iran:","authors":"Y. Ravanshad, A. Ghodsi, Mohaddeseh Golsorkhi, A. Azarfar, S. Ravanshad, Samaneh Heidarzadeh, Hamidreza Ghodsi, Aida Tasbandi","doi":"10.22037/JPN.VI.34617","DOIUrl":"https://doi.org/10.22037/JPN.VI.34617","url":null,"abstract":"Background and Aim: Kidney transplantation is the preferred treatment modality for end-stage renal disease (ESRD) in children. Despite its benefits and advances that have been accomplished, pediatric kidney transplantation remains a challenge in terms of achieving a satisfactory outcome. We sought to evaluate the outcome of pediatric kidney transplantation in Mashhad. \u0000Methods: Data were acquired retrospectively from children below 18 years old who underwent kidney transplantation in three main hospitals of Mashhad from 2000 to 2014. After obtaining written informed consent from parents, data were collected using a questionnaire and analyzed with the SPSS software. \u0000Results: Of 52 children, 51.9% were boys and 48.1% were girls with a mean age of 13.3 ± 4.3 years. Among them, 8 (15.4%) children received transplants from relative live donors, 16 (30.8%) from non-relative live donors, and 28 (53.8%) from deceased donors. The most common etiology leading to ESRD in these children was reflux nephropathy in 18 (34.6%) patients. After a 5-year follow-up period, the graft survival rate was 69.2% with infection being the most common cause of transplant rejection. Moreover, 13.5% of children died, mostly due to surgical complications. \u0000Conclusion: We found that to increase the survival rate of pediatric kidney transplantation in Mashhad, first the surgical methods should be enhanced as they were recognized as the most common cause of death. In addition, infection control in children, as the most common cause of transplant rejection, should be improved.","PeriodicalId":77809,"journal":{"name":"The International journal of pediatric nephrology","volume":"10 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2021-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85129218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative Study of Prophylactic Antibiotic Twice a Week versus Every Night in Recurrent Urinary Tract Infections in Children 每周两次预防性抗生素与每晚预防性抗生素治疗儿童反复尿路感染的比较研究

The International journal of pediatric nephrology Pub Date : 2021-09-18 DOI: 10.22037/JPN.V9I3.34181

Amin Taheri, A. Azarfar, Y. Ravanshad, Azade Sahebkari

{"title":"Comparative Study of Prophylactic Antibiotic Twice a Week versus Every Night in Recurrent Urinary Tract Infections in Children","authors":"Amin Taheri, A. Azarfar, Y. Ravanshad, Azade Sahebkari","doi":"10.22037/JPN.V9I3.34181","DOIUrl":"https://doi.org/10.22037/JPN.V9I3.34181","url":null,"abstract":"Background and Aim: Urinary tract infection is one of the most common childhood diseases. The results of studies investigating discontinuation or continuation of antibiotics in children with recurrent urinary tract infections and urinary reflux are controversial. Therefore, this study was conducted to compare prophylactic antibiotic treatment twice a week versus every night in the recurrence of urinary tract infections in children. \u0000Methods: This clinical trial was conducted using non-random simple sampling. Group A was given a single daily dose of cephalexin 10 mg/kg and group B was given cotrimoxazole at a dose of 5 mg/kg. Both groups were followed for ten months. Recurrences of urinary tract infections were compared between the two groups. \u0000Results: The mean age of the participants was 3.53±2.04 years. Most of the subjects were female (n=37, 61.7%). Urinary reflux was unilateral in 65% of the cases (n=39) and bilateral in the rest. There was no significant difference in age distribution, sex, and type of reflux between groups A and B. The frequency of recurrent urinary tract infection was 8.3% in group A and 6.7% in group B indicating no significant difference (p = 0.500). \u0000Conclusion: The results of this study showed that the frequency of recurrence of urinary tract infections in children who received prophylactic antibiotic treatment twice a week was not significantly different compared to the group of children who received continuous antibiotic prophylaxis.","PeriodicalId":77809,"journal":{"name":"The International journal of pediatric nephrology","volume":"32 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2021-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78500486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anaplastic Wilms’ Tumor Mimicking a Rhabdoid Tumor: A Diagnostic Challenge: 模拟横纹肌样瘤的间变性肾母细胞瘤:诊断挑战

The International journal of pediatric nephrology Pub Date : 2021-09-06 DOI: 10.22037/JPN.V9I3.35043

Smita Singh, K. Agarwal, A. Anand, N. Suman

引用次数: 0

Prognostic Role of Gestational Age and Birth Weight in Nephrotic Syndrome: A Retrospective Cross-Sectional Study 胎龄和出生体重对肾病综合征预后的影响:一项回顾性横断面研究

The International journal of pediatric nephrology Pub Date : 2021-09-06 DOI: 10.22037/JPN.V9I3.34482

K. Ghasemi, S. Montazeri, A. Mokhtari

{"title":"Prognostic Role of Gestational Age and Birth Weight in Nephrotic Syndrome: A Retrospective Cross-Sectional Study","authors":"K. Ghasemi, S. Montazeri, A. Mokhtari","doi":"10.22037/JPN.V9I3.34482","DOIUrl":"https://doi.org/10.22037/JPN.V9I3.34482","url":null,"abstract":"Background and Aim: Nephrotic syndrome (NS) is a common disease in children characterized by proteinuria, hypoalbunemia and hyperlipidemia. In some cases, NS is resistant to steroid therapy and may have frequent relapses. The aim of this study was to determine the prognostic role of gestational age and birth weight in the clinical outcomes of NS. \u0000Methods: This retrospective cross-sectional study was conducted on 77 patients. The patients’ data such as history of relapse and steroid resistance, birth weight, gestational age, and pathological variant were collected. Data was analysed using the SPSS software. \u0000Results: Twenty-three patients were females and 54 were males. There was no significant association between the number of recurrences and premature birth (P value= 0.99). Mann-Whitney U test showed no significant difference between birth weight of patients who recurred less than two times during six months and those who recurred more than two times in six months (P= 0.336). Besides, Fisher’s exact test showed no significant association between premature birth and the chance of developing steroid resistance (P value = 0.643). Moreover, there was no significant association between birth weight and steroid resistance (P-value = 0.768). \u0000Conclusion: Low birth weight and premature birth did not have a role in the prognosis of nephrotic syndrome in our study population. Other factors including uterine-placental disorders, maternal underlying diseases, quality of weight gain in the first years of life, and ethnicity should also be examined in further investigations including larger samples of different ethnic groups.","PeriodicalId":77809,"journal":{"name":"The International journal of pediatric nephrology","volume":"44 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2021-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85778508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1