Survey of immunologic research最新文献

Trends in current studies of phagocyte chemotaxis 吞噬细胞趋化性的最新研究趋势

Survey of immunologic research Pub Date : 2014-02-07 DOI: 10.1007/BF02918571

Liana Harvalh

引用次数: 0

Thymopentín as adjuvant to hepatitis vaccination Thymopentín作为肝炎疫苗的佐剂

Survey of immunologic research Pub Date : 1985-03-01 DOI: 10.1007/BF02919065

P. Grob, U. Binswanger, A. Blumberg, H. Gloor, A. Hany, W. Herwig, H. Jselin, K. Záruba, K. Bolla

引用次数: 1

Phenotyping the prothymocyte 胸腺原细胞表型

Survey of immunologic research Pub Date : 1985-03-01 DOI: 10.1007/BF02918581

Allen E. Silverstonea, Yvon Cayreb

引用次数: 3

Thymopentin treatment of herpes simplex infections 胸腺肽治疗单纯疱疹感染

Survey of immunologic research Pub Date : 1985-03-01 DOI: 10.1007/BF02919054

J. DeMaubeugea, E. Hanekeb, D. Djawaric, K. Wolffd, G. Stingld, L. Moline, E. Schöpff, R. Stengelf, H. Degreefg, E. Panconesih, B. Wüthrichi, K. Bollaj

引用次数: 2

Thymopentin in chronicTrichophyton rubrum infection 胸腺肽在慢性红毛癣菌感染中的作用

Survey of immunologic research Pub Date : 1985-03-01 DOI: 10.1007/BF02919069

L. Molin, B. K.

引用次数: 4

Thymopentin in active rheumatoid arthritis 胸腺肽在活动性类风湿关节炎中的作用

Survey of immunologic research Pub Date : 1985-03-01 DOI: 10.1007/BF02919061

P. Franchimont, C. Hauwaert, K. Bolla

引用次数: 2

Thymopentin treatment in AIDS and pre-AIDS patients. 胸腺肽在艾滋病和艾滋病前期患者中的治疗。

Survey of immunologic research Pub Date : 1985-01-01 DOI: 10.1007/BF02919057

N Clumeck, S Cran, P Van de Perre, F Mascart-Lemone, J Duchateau, K Bolla

{"title":"Thymopentin treatment in AIDS and pre-AIDS patients.","authors":"N Clumeck, S Cran, P Van de Perre, F Mascart-Lemone, J Duchateau, K Bolla","doi":"10.1007/BF02919057","DOIUrl":"https://doi.org/10.1007/BF02919057","url":null,"abstract":"Three pilot studies testing thymopentin in AIDS patients are presented. One study included 5 patients with the full-blown syndrome, all treated with 50 mg thymopentin 3 times a week by intravenous slow infusion; no immunologically nor clinically positive results were observed, indicating that the T cell pool in such patients is severely depleted. Six other patients with the prodromal stage of AIDS were treated 1 month with 50 mg thymopentin administered as an intravenous bolus injection 3 times weekly and thereafter for another month with same dose regimen as intravenous slow infusions. The patients on infusion therapy experienced statistically significant immunological improvements; these positive findings were paralleled with an improvement of the patients' clinical condition. These positive responses persisted for an average of 8 months. In another group of 5 pre-AIDS patients thymopentin was administered via the subcutaneous route using 15 mg 3 times weekly; only 1 patient revealed immunological and clinical improvement. In summary, only patients with the pre-AIDS syndrome are likely to benefit from immunomodulation therapy with thymopentin, and the mode of administration seems to be crucial.","PeriodicalId":77804,"journal":{"name":"Survey of immunologic research","volume":"4 Suppl 1 ","pages":"58-62"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02919057","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15014720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 20

Intrathymic differentiation: thymocyte heterogeneity and the characterization of early T-cell precursors. 胸腺内分化:胸腺细胞异质性和早期t细胞前体的表征。

Survey of immunologic research Pub Date : 1985-01-01 DOI: 10.1007/BF02918806

B J Fowlkes, B J Mathieson

{"title":"Intrathymic differentiation: thymocyte heterogeneity and the characterization of early T-cell precursors.","authors":"B J Fowlkes, B J Mathieson","doi":"10.1007/BF02918806","DOIUrl":"https://doi.org/10.1007/BF02918806","url":null,"abstract":"Multiparameter FCA of unfractionated or isolated subpopulations of thymocytes reveals at least seven subpopulations in the mouse thymus. One of these subpopulations, designated dLy1 has been isolated and characterized extensively. The data reviewed here indicate that the dLy1 thymocyte subpopulation, whether derived from the adult or fetal thymus, represents an early stage in intrathymic differentiation. The immature status of dLy1 cells was suggested by the extensive similarity to a predominant cell type that occurs early in fetal thymic ontogeny. Its precursor role was demonstrated by its capacity to generate cortical and medullary-type thymocytes in vivo. Its expression of Ly1, Thy-1 and mRNA specific for the beta-chain of the T-cell antigen receptor support its commitment to a T-cell developmental pathway. In summary, dLy1 thymocytes appear to be the earliest committed T cells yet to be described, isolated and characterized. Further investigation should reveal whether this subpopulation of thymocytes contains subsets of cells in earlier states of maturation and/or precursors already committed to more than one T-cell lineage.","PeriodicalId":77804,"journal":{"name":"Survey of immunologic research","volume":"4 2","pages":"96-109"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02918806","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15014899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 20

Modulation of immune response in aged humans through different administration modes of thymopentin 胸腺肽不同给药方式对老年人免疫反应的调节作用

Survey of immunologic research Pub Date : 1985-01-01 DOI: 10.1007/BF02919063

J. Duchateau, G. Servais, R. Vreyens, G. Delespesse, K. Bolla

引用次数: 26

Macrophages in the thymus. 胸腺中的巨噬细胞。

Survey of immunologic research Pub Date : 1985-01-01 DOI: 10.1007/BF02918671

G W Wood

引用次数: 0