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The interplay of surgeon judgment and available evidence in the long-term outcome of ventral hernia repair
IF 2.7 3区 医学
American journal of surgery Pub Date : 2025-03-07 DOI: 10.1016/j.amjsurg.2025.116292
Aymen H. Sadaka , William J. O'Brien , Kamal M.F. Itani
{"title":"The interplay of surgeon judgment and available evidence in the long-term outcome of ventral hernia repair","authors":"Aymen H. Sadaka ,&nbsp;William J. O'Brien ,&nbsp;Kamal M.F. Itani","doi":"10.1016/j.amjsurg.2025.116292","DOIUrl":"10.1016/j.amjsurg.2025.116292","url":null,"abstract":"<div><h3>Background</h3><div>Since 2011, the New England VA Hernia Registry (NEVAHR) prospectively collected operative details of ventral hernia repairs (VHRs) from 5 VA medical centers. This study aims to determine factors associated with recurrence.</div></div><div><h3>Methods</h3><div>Recurrence and surgical site occurrences (SSO) were directly identified via clinical and operative notes and/or imaging. Analysis was conducted via logistical regression.</div></div><div><h3>Results</h3><div>There were 681 VHRs. Mesh was used in 589 (86.5 ​%) repairs and was associated with larger average defect sizes (p ​&lt; ​0.001) and incisional hernias (p ​= ​0.007). There were 117 (19.9 ​%) recurrences among mesh repairs and 22 (23.9 ​%) among suture repairs (p ​= ​0.033). Among mesh repairs, recurrence was associated with higher BMI (p ​= ​0.009), smoking (p ​= ​0.012), parastomal and subcostal hernias (p ​= ​0.003; p ​= ​0.042), SSOs (p ​= ​0.009), laparoscopy (p ​= ​0.042), and smaller mesh-fascia overlap (p ​= ​0.039). No factors associated with recurrence among suture repairs.</div></div><div><h3>Conclusion</h3><div>Despite proper decision-making by NEVAHR surgeons, suture repair underperforms for hernias &gt;2 ​cm. Utility of suture repair for defects &lt;2 ​cm requires more investigation.</div></div>","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":"243 ","pages":"Article 116292"},"PeriodicalIF":2.7,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143621310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Healthcare disparities and fiscal challenges Medicaid payor proportions' role in academic medical center profit margins.
IF 2.7 3区 医学
American journal of surgery Pub Date : 2025-03-07 DOI: 10.1016/j.amjsurg.2025.116294
Tobi Somorin, Ju Hyung An, David Berger, Panos Kougias, Sherene Sharath
{"title":"Healthcare disparities and fiscal challenges Medicaid payor proportions' role in academic medical center profit margins.","authors":"Tobi Somorin, Ju Hyung An, David Berger, Panos Kougias, Sherene Sharath","doi":"10.1016/j.amjsurg.2025.116294","DOIUrl":"https://doi.org/10.1016/j.amjsurg.2025.116294","url":null,"abstract":"","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":" ","pages":"116294"},"PeriodicalIF":2.7,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The gender paradox in sepsis: Exploring male vulnerability and female resilience.
IF 2.7 3区 医学
American journal of surgery Pub Date : 2025-03-07 DOI: 10.1016/j.amjsurg.2025.116293
Jiyun Hu, Shucai Xie, Ya Liao, Tao Chen, Zhaoxin Qian, Lina Zhang
{"title":"The gender paradox in sepsis: Exploring male vulnerability and female resilience.","authors":"Jiyun Hu, Shucai Xie, Ya Liao, Tao Chen, Zhaoxin Qian, Lina Zhang","doi":"10.1016/j.amjsurg.2025.116293","DOIUrl":"https://doi.org/10.1016/j.amjsurg.2025.116293","url":null,"abstract":"<p><p>The role of gender in sepsis outcomes remains controversial. Numerous epidemiological studies investigating gender-dependent clinical outcomes in sepsis have yielded conflicting evidence. While the literature varies, most studies indicate that male gender is associated with worse sepsis outcomes and survival. Understanding the gender's role in these processes provides valuable insights into potential therapeutic targets for sepsis.</p>","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":" ","pages":"116293"},"PeriodicalIF":2.7,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Incorporating ergonomics into surgical checklist workflows. 将人体工程学纳入手术清单工作流程。
IF 2.7 3区 医学
American journal of surgery Pub Date : 2025-03-05 DOI: 10.1016/j.amjsurg.2025.116281
Andrew T Gabrielson, Ankur Mukherjee, Fahad Alam, Julie Hallet
{"title":"Incorporating ergonomics into surgical checklist workflows.","authors":"Andrew T Gabrielson, Ankur Mukherjee, Fahad Alam, Julie Hallet","doi":"10.1016/j.amjsurg.2025.116281","DOIUrl":"https://doi.org/10.1016/j.amjsurg.2025.116281","url":null,"abstract":"","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":" ","pages":"116281"},"PeriodicalIF":2.7,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Roses & thorns of academic surgery: Paving the way for others with Dr. Paula Ferrada.
IF 2.7 3区 医学
American journal of surgery Pub Date : 2025-03-05 DOI: 10.1016/j.amjsurg.2025.116290
Mytien Nguyen, Alizeh Abbas, Lamario J Williams, Wendelyn M Oslock, Ranganath G Kathawate, Paula A Ferrada
{"title":"Roses & thorns of academic surgery: Paving the way for others with Dr. Paula Ferrada.","authors":"Mytien Nguyen, Alizeh Abbas, Lamario J Williams, Wendelyn M Oslock, Ranganath G Kathawate, Paula A Ferrada","doi":"10.1016/j.amjsurg.2025.116290","DOIUrl":"https://doi.org/10.1016/j.amjsurg.2025.116290","url":null,"abstract":"","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":" ","pages":"116290"},"PeriodicalIF":2.7,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inflammatory breast cancer response to modern neoadjuvant chemotherapy: Tumor response and survival outcomes
IF 2.7 3区 医学
American journal of surgery Pub Date : 2025-03-05 DOI: 10.1016/j.amjsurg.2025.116288
Dorsa Mousa-Doust , Amy Bazzarelli , Melina Deban , Carol Dingee , Jieun Newman-Bremang , Jin-Si Pao , Rebecca Warburton , Elaine McKevitt
{"title":"Inflammatory breast cancer response to modern neoadjuvant chemotherapy: Tumor response and survival outcomes","authors":"Dorsa Mousa-Doust ,&nbsp;Amy Bazzarelli ,&nbsp;Melina Deban ,&nbsp;Carol Dingee ,&nbsp;Jieun Newman-Bremang ,&nbsp;Jin-Si Pao ,&nbsp;Rebecca Warburton ,&nbsp;Elaine McKevitt","doi":"10.1016/j.amjsurg.2025.116288","DOIUrl":"10.1016/j.amjsurg.2025.116288","url":null,"abstract":"<div><h3>Background</h3><div>Inflammatory breast cancer (IBC) is a rare, aggressive form of breast cancer. This study evaluates oncologic outcomes in IBC patients treated with modern multimodal treatment.</div></div><div><h3>Methods</h3><div>A retrospective review analyzed clinicopathologic data of 5063 patients, 646 of whom underwent NAC followed by surgery between 2012 and 2024. Survival outcomes were compared across biologic subtypes.</div></div><div><h3>Results</h3><div>Twenty-six cases of T4dM0 IBC were identified, with 57.7 ​% HER-2 positive, 26.9 ​% ER positive/HER-2 negative, and 15.4 ​% ER negative/HER-2 negative. The total pCR rate was highest in HER-2 positive (53.3 ​%) and lowest in ER-positive/HER-2 negative patients (p ​= ​0.036). Among 19 patients with ≥3 years of follow-up, 47 ​% experienced recurrence (78 ​% distant and 22 ​% locoregional) and 42 ​% died of breast cancer. No significant differences in locoregional recurrence, or survival outcomes were found across subtypes.</div></div><div><h3>Conclusion</h3><div>pCR has limited prognostic value in IBC. Although HER-2 positive patients are more likely to achieve pCR, this does not necessarily translate into improved outcomes.</div></div>","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":"243 ","pages":"Article 116288"},"PeriodicalIF":2.7,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143621311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of social determinants of health on patient outcomes in acute trauma: A systematic review
IF 2.7 3区 医学
American journal of surgery Pub Date : 2025-03-05 DOI: 10.1016/j.amjsurg.2025.116284
Jaclyn N Portelli Tremont, Erik H. Ander, Szu-In Lim, Jared R. Gallaher, Trista Reid
{"title":"The effect of social determinants of health on patient outcomes in acute trauma: A systematic review","authors":"Jaclyn N Portelli Tremont,&nbsp;Erik H. Ander,&nbsp;Szu-In Lim,&nbsp;Jared R. Gallaher,&nbsp;Trista Reid","doi":"10.1016/j.amjsurg.2025.116284","DOIUrl":"10.1016/j.amjsurg.2025.116284","url":null,"abstract":"<div><h3>Introduction</h3><div>Social determinants of health (SDoH) may mediate disparities, but their effect on outcomes after trauma is not well known. The purpose of this review is to improve existing gaps of knowledge for a broad range of SDoH and trauma-related outcomes.</div></div><div><h3>Methods</h3><div>This was a systematic search to identify studies that evaluated the effect of race, insurance status, socioeconomic status (SES), health literacy, and community deprivation on inpatient mortality, morbidity, and post-discharge health care utilization in diverse trauma populations ≥16 years. Data were extracted on study design, patient and injury characteristics, outcomes, and covariates. Qualitative analysis was performed and reported results were stratified by exposure. An overall assessment of the strength of evidence for key clinically relevant comparisons was conducted.</div></div><div><h3>Results</h3><div>60 studies were included. Overall, race was not meaningfully predictive of mortality or morbidity, with evidence reporting inconsistent or small magnitude of effects. However, African American/Black race was consistently associated with decreased odds of discharge to rehabilitation. Compared to insured patients, uninsured patients may have greater mortality risk and be less likely to discharge to rehabilitation. Studies evaluating health literacy or community deprivation reported conflicting results.</div></div><div><h3>Conclusions</h3><div>Disparities related to race are most profound for post-discharge health care utilization, while insurance status may be a strong negative predictor of both mortality and discharge disposition. More research is needed on health literacy and community deprivation to better understand mechanisms of disparity after trauma. Interventions targeted at improving continuity of inpatient and outpatient care may be beneficial.</div></div>","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":"243 ","pages":"Article 116284"},"PeriodicalIF":2.7,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143609311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sheltered yet unscreened: Exploring cancer screening rates and barriers in the unhoused (homeless) population
IF 2.7 3区 医学
American journal of surgery Pub Date : 2025-03-04 DOI: 10.1016/j.amjsurg.2025.116289
Talal Al-Assil , Claire Kalina , Madison C. Laird , Ryan C. Olivier , Nataly Dawood , Neya Suresh Kumar , Raven Riordan , Saad Shebrain , Cheryl Dickson , Gitonga Munene
{"title":"Sheltered yet unscreened: Exploring cancer screening rates and barriers in the unhoused (homeless) population","authors":"Talal Al-Assil ,&nbsp;Claire Kalina ,&nbsp;Madison C. Laird ,&nbsp;Ryan C. Olivier ,&nbsp;Nataly Dawood ,&nbsp;Neya Suresh Kumar ,&nbsp;Raven Riordan ,&nbsp;Saad Shebrain ,&nbsp;Cheryl Dickson ,&nbsp;Gitonga Munene","doi":"10.1016/j.amjsurg.2025.116289","DOIUrl":"10.1016/j.amjsurg.2025.116289","url":null,"abstract":"<div><h3>Introduction</h3><div>Cancer related mortality amongst the homeless and unhoused has been reported to be significantly higher than the housed population. This study explores cancer screening uptake and barriers in a homeless community in Michigan.</div></div><div><h3>Methods</h3><div>Questionnaires were administered at two homeless shelters focusing on Hepatitis C (HCV), lung, breast, colon, and cervical cancer screenings.</div></div><div><h3>Results</h3><div>Amongst 143 participants, rates of screening uptake were lowest for breast cancer (44 ​%), followed by colorectal cancer (45 ​%), HCV (55 ​%), and cervical cancer (79 ​%). The three most common barriers to receiving screenings were lack of transportation (21.8 ​%), lack of access to or awareness of screenings (20.5 ​%), and low prioritization of health compared to other insecurities faced while being homeless (17.9 ​%).</div></div><div><h3>Conclusions</h3><div>Enhancing the unhoused/homeless community's access to cancer screenings is crucial. High willingness to undergo screenings suggests potential targeted interventions, such as providing transportation tokens and comprehensive educational resources, onsite screenings, and potentially employing social work navigators at shelters.</div></div>","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":"248 ","pages":"Article 116289"},"PeriodicalIF":2.7,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143642280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From past to present: A comparison of interpersonal firearm violence between historically graded neighborhoods of Kansas City 从过去到现在:堪萨斯城历史上分级街区之间人际枪支暴力的比较
IF 2.7 3区 医学
American journal of surgery Pub Date : 2025-03-04 DOI: 10.1016/j.amjsurg.2025.116287
Terra M. Hill , Lauren T. Kerivan , Milind Phadnis , Christopher A. Guidry , Robert D. Winfield
{"title":"From past to present: A comparison of interpersonal firearm violence between historically graded neighborhoods of Kansas City","authors":"Terra M. Hill ,&nbsp;Lauren T. Kerivan ,&nbsp;Milind Phadnis ,&nbsp;Christopher A. Guidry ,&nbsp;Robert D. Winfield","doi":"10.1016/j.amjsurg.2025.116287","DOIUrl":"10.1016/j.amjsurg.2025.116287","url":null,"abstract":"<div><h3>Background</h3><div>Interpersonal firearm violence (IFV) has been connected to the structural racism of redlining. We explored the relationship between historic redlining and IFV with population-level factors.</div></div><div><h3>Methods</h3><div>A cross-sectional study of IFV within historically graded neighborhoods was performed, and incidence rate ratios (IRRs) between these neighborhoods and the rate of IFV were modeled with a Poisson regression model.</div></div><div><h3>Results</h3><div>Comparing redlined to non-redlined neighborhoods, the IRRs adjusted for income was 14.9 (p ​&lt; ​0.0001), adjusted for poverty was 14.4 (p ​&lt; ​0.0001), adjusted for uninsured was 15.6 (p ​&lt; ​0.0001), and adjusted for IFV-related mortality was 26.05 (p ​&lt; ​0.0001). After county adjustment, every one unit increase in logarithm of income decreases the IFV rate by 64.7 ​% (p ​&lt; ​0.0001), whereas every one percent increase of poverty and uninsured, increases the IFV rates by 4.1 ​% (p ​&lt; ​0.0001) and 3.05 ​% (p ​&lt; ​0.0002), respectively.</div></div><div><h3>Conclusion</h3><div>Historically redlined communities have higher rates of IFV in Kansas City, Kansas.</div></div>","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":"248 ","pages":"Article 116287"},"PeriodicalIF":2.7,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143561742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of immediate symmetrizing oncoplastic surgery with patient-reported outcomes in patients with breast cancer – A retrospective cohort study
IF 2.7 3区 医学
American journal of surgery Pub Date : 2025-03-04 DOI: 10.1016/j.amjsurg.2025.116286
Martin Heidinger , Gilles Bilfeld , Nico Föge , Julie M. Loesch , Nadia Maggi , Rama Kiblawi , Ruth S. Eller , Marie Louise Frevert , Fabienne D. Schwab , Christian Kurzeder , Tibor A. Zwimpfer , Walter P. Weber
{"title":"Association of immediate symmetrizing oncoplastic surgery with patient-reported outcomes in patients with breast cancer – A retrospective cohort study","authors":"Martin Heidinger ,&nbsp;Gilles Bilfeld ,&nbsp;Nico Föge ,&nbsp;Julie M. Loesch ,&nbsp;Nadia Maggi ,&nbsp;Rama Kiblawi ,&nbsp;Ruth S. Eller ,&nbsp;Marie Louise Frevert ,&nbsp;Fabienne D. Schwab ,&nbsp;Christian Kurzeder ,&nbsp;Tibor A. Zwimpfer ,&nbsp;Walter P. Weber","doi":"10.1016/j.amjsurg.2025.116286","DOIUrl":"10.1016/j.amjsurg.2025.116286","url":null,"abstract":"<div><h3>Introduction</h3><div>Oncoplastic breast surgery (OPS) with immediate symmetrization is commonly performed. However, its impact on patient-reported outcomes (PROs) remains uncertain.</div></div><div><h3>Methods</h3><div>Patients with stage 0-III breast cancer who underwent OPS (including oncoplastic breast conserving surgery, or nipple- or skin-sparing mastectomy) at a Swiss university hospital between 01/2013-12/2023 who completed a postoperative BREAST-Q questionnaire were identified from a prospectively maintained database. A generalized linear model was used to detect differences in PROs between those who underwent unilateral versus immediate symmetrizing surgery.</div></div><div><h3>Results</h3><div>Of 441 eligible patients, 333 (75.5 ​%) underwent unilateral OPS, while 108 (24.5 ​%) underwent bilateral OPS. Median time to PRO assessment was 35.1 months (Q1-Q3 13.4–49.5). No differences in PROs were identified between patients who underwent unilateral versus bilateral OPS. Short-term surgical morbidity was more common in patients who underwent symmetrizing surgery, which negatively impacted PROs.</div></div><div><h3>Conclusion</h3><div>The present study did not demonstrate any impact of immediate symmetrization on PROs.</div></div>","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":"243 ","pages":"Article 116286"},"PeriodicalIF":2.7,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143577165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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