{"title":"Metabolic bone disease and Paget's disease in the elderly. Part II: Paget's disease.","authors":"R L Merkow, J M Lane","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77693,"journal":{"name":"Clinics in rheumatic diseases","volume":"12 1","pages":"70-96"},"PeriodicalIF":0.0,"publicationDate":"1986-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14219193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Metabolic bone disease and Paget's disease in the elderly. Part I: Metabolic bone disease.","authors":"J M Lane, J R Werntz, J H Healey, V J Vigorita","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77693,"journal":{"name":"Clinics in rheumatic diseases","volume":"12 1","pages":"49-70"},"PeriodicalIF":0.0,"publicationDate":"1986-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14645086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Disease-modifying Agents and Immunosuppressive Drugs in the Elderly","authors":"Joseph W. O'callaghan, Peter M. Brooks","doi":"10.1016/S0307-742X(21)00630-5","DOIUrl":"https://doi.org/10.1016/S0307-742X(21)00630-5","url":null,"abstract":"<div><p>Disease-modifying and immunosuppressive therapies are required for elderly patients with rheumatic disorders. The evidence to date suggests that the criteria for choosing a particular drug is not vastly different from the choice in younger patients, and that the elderly have a similar response. More care is required in monitoring elderly patients on immunosuppressive drugs because of the potential for increased adverse reactions consequent on reduced functional capacity of major end organs. There is little data available to judge relative efficacy of these drugs in the elderly and with the ‘greying’ of the population these data should be sought after.</p><p>With careful individual choice of drug and regular reassessment for effect and adverse drug reactions, many elderly patients with rheumatic diseases can obtain useful benefit from these agents.</p></div>","PeriodicalId":77693,"journal":{"name":"Clinics in rheumatic diseases","volume":"12 1","pages":"Pages 275-289"},"PeriodicalIF":0.0,"publicationDate":"1986-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137228346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Immunology of Ageing","authors":"Peter M. Ford","doi":"10.1016/S0307-742X(21)00617-2","DOIUrl":"https://doi.org/10.1016/S0307-742X(21)00617-2","url":null,"abstract":"","PeriodicalId":77693,"journal":{"name":"Clinics in rheumatic diseases","volume":"12 1","pages":"Pages 1-10"},"PeriodicalIF":0.0,"publicationDate":"1986-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136695287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Connective Tissue Disease in the Elderly","authors":"Mary Betty Stevens","doi":"10.1016/S0307-742X(21)00618-4","DOIUrl":"https://doi.org/10.1016/S0307-742X(21)00618-4","url":null,"abstract":"<div><p>The prevalence of the inflammatory disorders of connective tissue in the older age group is quite likely underestimated at the present time; and, in most instances, age-related factors influencing clinical expression and auto-reactivity have not been intensively studied.</p><p>The array of connective tissue disease that usually targets the young adult emerges in the older age group as well; and, selectively in the elderly, GCA and PMR are found. The association of malignancy with PM/DM is increased with advanced age.</p><p>In view of the therapeutic implications, early diagnosis is essential, but this can be especially difficult in the setting of problems related to the ageing process.</p></div>","PeriodicalId":77693,"journal":{"name":"Clinics in rheumatic diseases","volume":"12 1","pages":"Pages 11-32"},"PeriodicalIF":0.0,"publicationDate":"1986-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136695288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Part II: Paget's Disease","authors":"Robert L. Merkow, Joseph M. Lane","doi":"10.1016/S0307-742X(21)00621-4","DOIUrl":"https://doi.org/10.1016/S0307-742X(21)00621-4","url":null,"abstract":"","PeriodicalId":77693,"journal":{"name":"Clinics in rheumatic diseases","volume":"12 1","pages":"Pages 70-96"},"PeriodicalIF":0.0,"publicationDate":"1986-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136705727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ageing in Relation to the Pathogenesis of Osteoarthritis","authors":"Kenneth D. Brandt, Rose S. Fife","doi":"10.1016/S0307-742X(21)00623-8","DOIUrl":"https://doi.org/10.1016/S0307-742X(21)00623-8","url":null,"abstract":"","PeriodicalId":77693,"journal":{"name":"Clinics in rheumatic diseases","volume":"12 1","pages":"Pages 117-130"},"PeriodicalIF":0.0,"publicationDate":"1986-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136705728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}