{"title":"老年人结缔组织疾病","authors":"Mary Betty Stevens","doi":"10.1016/S0307-742X(21)00618-4","DOIUrl":null,"url":null,"abstract":"<div><p>The prevalence of the inflammatory disorders of connective tissue in the older age group is quite likely underestimated at the present time; and, in most instances, age-related factors influencing clinical expression and auto-reactivity have not been intensively studied.</p><p>The array of connective tissue disease that usually targets the young adult emerges in the older age group as well; and, selectively in the elderly, GCA and PMR are found. The association of malignancy with PM/DM is increased with advanced age.</p><p>In view of the therapeutic implications, early diagnosis is essential, but this can be especially difficult in the setting of problems related to the ageing process.</p></div>","PeriodicalId":77693,"journal":{"name":"Clinics in rheumatic diseases","volume":"12 1","pages":"Pages 11-32"},"PeriodicalIF":0.0000,"publicationDate":"1986-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Connective Tissue Disease in the Elderly\",\"authors\":\"Mary Betty Stevens\",\"doi\":\"10.1016/S0307-742X(21)00618-4\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>The prevalence of the inflammatory disorders of connective tissue in the older age group is quite likely underestimated at the present time; and, in most instances, age-related factors influencing clinical expression and auto-reactivity have not been intensively studied.</p><p>The array of connective tissue disease that usually targets the young adult emerges in the older age group as well; and, selectively in the elderly, GCA and PMR are found. The association of malignancy with PM/DM is increased with advanced age.</p><p>In view of the therapeutic implications, early diagnosis is essential, but this can be especially difficult in the setting of problems related to the ageing process.</p></div>\",\"PeriodicalId\":77693,\"journal\":{\"name\":\"Clinics in rheumatic diseases\",\"volume\":\"12 1\",\"pages\":\"Pages 11-32\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1986-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinics in rheumatic diseases\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0307742X21006184\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinics in rheumatic diseases","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0307742X21006184","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The prevalence of the inflammatory disorders of connective tissue in the older age group is quite likely underestimated at the present time; and, in most instances, age-related factors influencing clinical expression and auto-reactivity have not been intensively studied.
The array of connective tissue disease that usually targets the young adult emerges in the older age group as well; and, selectively in the elderly, GCA and PMR are found. The association of malignancy with PM/DM is increased with advanced age.
In view of the therapeutic implications, early diagnosis is essential, but this can be especially difficult in the setting of problems related to the ageing process.
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