American journal of reproductive immunology and microbiology : AJRIM最新文献

Correlations between results of the immunobead test and the sperm penetration assay. 免疫珠试验结果与精子穿透试验结果的相关性。

American journal of reproductive immunology and microbiology : AJRIM Pub Date : 1989-02-01 DOI: 10.1097/00006254-198902000-00025

B. Gocial, S. Corson, F. Batzer, G. Maislin, J. Marmar

引用次数: 2

Production of immunosuppressor factor(s) by preimplantation human embryos. 人胚胎植入前免疫抑制因子的产生。

American journal of reproductive immunology and microbiology : AJRIM Pub Date : 1988-08-01

M Adinolfi

引用次数: 0

Immunohistochemical characterization of stromal leucocytes in nonpregnant human endometrium. 未怀孕人子宫内膜间质白细胞的免疫组织化学特征。

American journal of reproductive immunology and microbiology : AJRIM Pub Date : 1988-07-01 DOI: 10.1097/00006254-198904000-00019

J. Bulmer, D. Lunny, Susan V. HAGlN

引用次数: 99

Heterosexual transmission of AIDS. 艾滋病的异性传播。

American journal of reproductive immunology and microbiology : AJRIM Pub Date : 1988-01-01 DOI: 10.7326/0003-4819-113-7-564_3

N. Alexander

引用次数: 0

Genetic factors in fetal losses. 胎儿流产的遗传因素。

American journal of reproductive immunology and microbiology : AJRIM Pub Date : 1987-12-01

T J Gill

引用次数: 0

Prenatal effects of maternal-fetal HLA compatibility. 母胎HLA相容性的产前影响。

American journal of reproductive immunology and microbiology : AJRIM Pub Date : 1987-12-01 DOI: 10.1097/00006254-198806000-00015

Carole Ober, J. Simpson, Michael Ward, Ruta M. Radvany, Rhonda L. Andersen, Sherman Elias, R. Sabbagha

{"title":"Prenatal effects of maternal-fetal HLA compatibility.","authors":"Carole Ober, J. Simpson, Michael Ward, Ruta M. Radvany, Rhonda L. Andersen, Sherman Elias, R. Sabbagha","doi":"10.1097/00006254-198806000-00015","DOIUrl":"https://doi.org/10.1097/00006254-198806000-00015","url":null,"abstract":"Both retrospective studies of idiopathic aborters, as well as prospective studies of normal couples, have shown reduced fertility among couples sharing HLA antigens. However, the effects of maternal-fetal histocompatibility on surviving embryos are largely univestigated. We thus prospectively studied 53 healthy, fertile women whose timed pregnancies were verified within 21 days of conception. Maternal-fetal histocompatibility status was determined for HLA-A,-B, and -DR locus antigens. Fetal growth rates were monitored by ultrasound at 8, 12, and 20 weeks gestation. Neonates were weighed, measured (birthlength, chest circumference, head circumference), and examined within 72 h of delivery (116 major and minor anomalies) in standardized fashion by one of two geneticists. Although no significant differences were found between infants compatible and incompatible at the HLA-A or HLA-B locus, significant differences were observed between HLA-DR compatible and incompatible infants for sex ratios (p less than .003) and minor anomaly rates (p less than .05). Although differences in mean birthweights between HLA-DR compatible and incompatible infants were not significant in this sample, HLA-DR compatible infants were on average 200 grams smaller than HLA-DR incompatible infants. We interpret these findings as evidence for selection against histocompatible fetuses throughout gestation, particularly with respect to HLA-DR compatibility. Potential immunologic and genetic mechanisms are discussed.","PeriodicalId":77662,"journal":{"name":"American journal of reproductive immunology and microbiology : AJRIM","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1987-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87835205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 28

Influence of major histo(in)compatibility complex on reproduction. 主要历史相容性复合体对生殖的影响。

American journal of reproductive immunology and microbiology : AJRIM Pub Date : 1987-12-01

J Singh, I C Verma

{"title":"Influence of major histo(in)compatibility complex on reproduction.","authors":"J Singh, I C Verma","doi":"","DOIUrl":"","url":null,"abstract":"Approximately 80% of all human conceptions are lost prior to term, and about 6% of all human newborns exhibit in-utero fetal growth retardation resulting in perinatal mortality and a major share of perinatal morbidity. Recent interest has focused on the plausibility of an MHC-linked immunological effect in cases of spontaneous abortions in which no possible cause, particularly a chromosome abnormality, is indicated. Paradoxically, placenta has been shown to serve as an efficient immunosorbent where antipaternal MHC antibodies on binding to target MHC antigen-bearing placenta are internalized and rapidly degraded, thereby preventing potential damage to the fetus. We, in our attempts to resolve if active immune responses on the part of female following early recognitive events during pregnancy play any decisive role in the reproductive process, raised a highly inbred colony of mice (Balb/cJ, Jackson Labs, USA) to produce H-Y antibodies. An outbred colony of mice (Swiss, AIIMS) was maintained to study the cumulated effect of H-Y and H-2 antibodies on the sex ratio, reproductive performance, litter size, and fetal wastage. A definite sex ratio was observed in control groups. However, the H-Y antibodies produced by hyperimmunized inbred female mice before fertilization, significantly (P less than 0.01) reduced the sex ratio. The combined effect of H-Y and H-2 antibodies on the pregnant outbred mice produced more lethal congenital abnormalities. There was a significant (P less than or equal to 0.01) loss in the reproductive performance of male mice born from hyperimmunized female mice both inbred and outbred colonies.(ABSTRACT TRUNCATED AT 250 WORDS)","PeriodicalId":77662,"journal":{"name":"American journal of reproductive immunology and microbiology : AJRIM","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1987-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14559511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prenatal effects of maternal-fetal HLA compatibility. 母胎HLA相容性的产前影响。

American journal of reproductive immunology and microbiology : AJRIM Pub Date : 1987-12-01

C Ober, J L Simpson, M Ward, R M Radvany, R Andersen, S Elias, R Sabbagha

{"title":"Prenatal effects of maternal-fetal HLA compatibility.","authors":"C Ober, J L Simpson, M Ward, R M Radvany, R Andersen, S Elias, R Sabbagha","doi":"","DOIUrl":"","url":null,"abstract":"Both retrospective studies of idiopathic aborters, as well as prospective studies of normal couples, have shown reduced fertility among couples sharing HLA antigens. However, the effects of maternal-fetal histocompatibility on surviving embryos are largely univestigated. We thus prospectively studied 53 healthy, fertile women whose timed pregnancies were verified within 21 days of conception. Maternal-fetal histocompatibility status was determined for HLA-A,-B, and -DR locus antigens. Fetal growth rates were monitored by ultrasound at 8, 12, and 20 weeks gestation. Neonates were weighed, measured (birthlength, chest circumference, head circumference), and examined within 72 h of delivery (116 major and minor anomalies) in standardized fashion by one of two geneticists. Although no significant differences were found between infants compatible and incompatible at the HLA-A or HLA-B locus, significant differences were observed between HLA-DR compatible and incompatible infants for sex ratios (p less than .003) and minor anomaly rates (p less than .05). Although differences in mean birthweights between HLA-DR compatible and incompatible infants were not significant in this sample, HLA-DR compatible infants were on average 200 grams smaller than HLA-DR incompatible infants. We interpret these findings as evidence for selection against histocompatible fetuses throughout gestation, particularly with respect to HLA-DR compatibility. Potential immunologic and genetic mechanisms are discussed.","PeriodicalId":77662,"journal":{"name":"American journal of reproductive immunology and microbiology : AJRIM","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1987-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14605013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical significance of naturally occurring anti-zona pellucida antibodies in infertile women. 不孕症妇女天然抗透明带抗体的临床意义。

American journal of reproductive immunology and microbiology : AJRIM Pub Date : 1987-12-01

M R Caudle, C A Shivers, R A Wild

引用次数: 0

Immunology and birth defects: introduction to special issue. 免疫学与出生缺陷:特刊导论。

American journal of reproductive immunology and microbiology : AJRIM Pub Date : 1987-12-01

D A Clark

引用次数: 0