The Journal of heart transplantation最新文献_第7页

Patients who refuse heart transplantation. 拒绝心脏移植的患者。

The Journal of heart transplantation Pub Date : 1990-07-01

R L Frierson, J B Tabler, S B Lippmann, A F Brennan

引用次数: 0

Anatomic characteristics and valvular function of the transplanted heart: transthoracic versus transesophageal echocardiographic findings. 移植心脏的解剖特征和瓣膜功能:经胸和经食管超声心动图的表现。

The Journal of heart transplantation Pub Date : 1990-07-01

C E Angermann, C H Spes, A Tammen, H U Stempfle, A Schütz, B M Kemkes, K Theisen

{"title":"Anatomic characteristics and valvular function of the transplanted heart: transthoracic versus transesophageal echocardiographic findings.","authors":"C E Angermann, C H Spes, A Tammen, H U Stempfle, A Schütz, B M Kemkes, K Theisen","doi":"","DOIUrl":"","url":null,"abstract":"In orthotopic heart transplantation atrial size and geometry are altered, whereas ventricles and atrioventricular valves remain structurally unchanged. To analyze the anatomy and function of the transplanted heart, 20 heart transplant recipients, with a mean age of 46.0 +/- 11.8 years, were examined with transthoracic echocardiography (TTE) and transesophageal echocardiography (TEE). Both methods showed atrial enlargement and abnormal configurations of the atria. Although valve leaflet structure appeared normal, TEE showed mitral regurgitation in 13 patients (TTE, 11), mitral prolapse in three patients (TTE, two), tricuspid regurgitation in 17 patients (TTE, 17), and tricuspid prolapse in two patients (TTE, one). Only by TEE, \"pseudoaneurysms\" of the donor part of the interatrial septum were found in six patients and of the receiver part in one patient, possibly as consequence of unequal thickness, asynchronous contraction, and cyclic torsion of both atrial components during the cardiac cycle. Spontaneous atrial echo contrast--again visualized only by TEE--was seen in five patients and a left atrial thrombus in three patients. Spontaneous echo contrast and thrombus formation were associated. One patient with a thrombus had had peripheral arterial embolism. We conclude that, compared with TTE, TEE offers superior imaging of cardiac anatomy, intraatrial abnormalities, and function of the atrioventricular valves. Mitral and tricuspid incompetence are frequent after orthotopic heart transplantation and may be related to abnormal atrial size and function, leading to impaired functional integrity of the valvular apparatus. The high incidence of atrial spontaneous echo contrast and thrombi suggests that antiplatelet or anticoagulant therapy may be advisable in heart transplant recipients with these findings.","PeriodicalId":77638,"journal":{"name":"The Journal of heart transplantation","volume":"9 4","pages":"331-8"},"PeriodicalIF":0.0,"publicationDate":"1990-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13546267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acute humoral rejection: a new entity in the histopathology of heart transplantation. 急性体液性排斥:心脏移植组织病理学中的一个新实体。

The Journal of heart transplantation Pub Date : 1990-07-01

J Kemnitz, I Restrepo-Specht, A Haverich, J Cremer

引用次数: 0

Plasma atrial natriuretic factor concentration in a heart-lung transplant recipient. 心肺移植受者血浆房利钠因子浓度。

The Journal of heart transplantation Pub Date : 1990-07-01

M Hynynen, A L Harjula, M Salmenperä, I Tikkanen, F Fyhrquist, S Mattila

引用次数: 0

Single-lung allotransplantation in pigs: effects of two preservation methods on pulmonary gas exchange. 猪单肺异体移植:两种保存方法对肺气体交换的影响。

The Journal of heart transplantation Pub Date : 1990-07-01

T S Kurki, A L Harjula, L J Heikkilä, A L Lehtola, P Hämmäinen, E Taskinen, S P Mattila

{"title":"Single-lung allotransplantation in pigs: effects of two preservation methods on pulmonary gas exchange.","authors":"T S Kurki, A L Harjula, L J Heikkilä, A L Lehtola, P Hämmäinen, E Taskinen, S P Mattila","doi":"","DOIUrl":"","url":null,"abstract":"Single left lung allotransplantation was performed in 16 pigs to determine an optimal solution for lung preservation. Modified Euro-Collins and oxygenated fluorocarbon solutions (FC-43) were used as the lung preservative. Donors in both groups were pretreated with intravenous prostaglandin E1 infusions. The effects of the two different preservatives on ventilation and oxygenation were noninvasively monitored with capnometry and pulse oximetry. The functional results were further compared with morphologic findings. After implantation the right pulmonary artery was clamped, and the transplanted lung supported pulmonary circulation and ventilation. Arterial carbon dioxide tension (PaCO2) and arterial oxygen tension (PaO2) were measured from the arterial blood samples. The Euro-Collins group experienced hypercarbia (PaCO2, 54 to 72 mm Hg) and low end-tidal carbon dioxide (EtCO2) values (3.3% to 3.9%) when the donor lung was reimplanted and reperfused. The pigs in the Euro-Collins group were also hypoxemic after reimplantation of the left lung. The saturation (SpO2) values were 85% to 89%, and the PaO2 values were between 61 and 66 mm Hg. The oxygenated fluorocarbon group had normal ventilatory parameters and arterial oxygen saturation after reimplantation of the left lung; no significant gradient between EtCO2 and PaCO2 was detected. Scanning and transmission electron-microscopic studies of the transplanted lungs showed good to moderate preservation after reperfusion in the oxygenated fluorocarbon group, whereas preservation was judged to be moderate in the Euro-Collins group. Oxygenated fluorocarbon (FC-43) donor lung preservation thus resulted in superior functional recovery in pulmonary gas exchange during reperfusion compared with Euro-Collins solution. Electron-microscopic findings supported functional results obtained.","PeriodicalId":77638,"journal":{"name":"The Journal of heart transplantation","volume":"9 4","pages":"424-8"},"PeriodicalIF":0.0,"publicationDate":"1990-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13548222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical survey of heart transplantation between ABO blood group-incompatible recipients and donors. ABO血型不相容受者与供者心脏移植的临床调查。

The Journal of heart transplantation Pub Date : 1990-07-01

D K Cooper

引用次数: 0

Treatment of cardiac allograft failure by use of an intraaortic axial flow pump. 应用主动脉内轴流泵治疗同种异体心脏移植衰竭。

The Journal of heart transplantation Pub Date : 1990-07-01

O H Frazier, M P Macris, R K Wampler, J M Duncan, M S Sweeney, J M Fuqua

{"title":"Treatment of cardiac allograft failure by use of an intraaortic axial flow pump.","authors":"O H Frazier, M P Macris, R K Wampler, J M Duncan, M S Sweeney, J M Fuqua","doi":"","DOIUrl":"","url":null,"abstract":"Since April 1988 we have used the Hemopump device, a new means of circulatory support, to successfully treat three orthotopic heart transplant recipients with biventricular failure refractory to conventional therapy. The Hemopump device is a 21F catheter-mounted, transvalvular, intraaortic axial flow pump. Power to the pump is percutaneously transmitted from an external electromechanical drive console by a flexible drive cable. We first used the pump in a 61-year-old man in whom severe steroid-resistant rejection developed 28 days after heart transplant, resulting in cardiogenic shock (cardiac index less than 2.0 L/min/m2) despite maximal inotropic support. In the second case a 49-year-old man with no evidence of pulmonary hypertension sustained cardiac arrest 2 hours after heart transplant, necessitating open chest massage and emergency cardiopulmonary bypass. The third patient was a 9-year-old boy in whom rejection developed 5 months after heart transplant, resulting in congestive heart failure that was unresponsive to maximal medical therapy. The device was implanted by way of the femoral artery approach in the first case, the ascending aorta in the second, and the distal abdominal aorta in the third. Duration of support was 46 hours, 65 hours, and 6 days, respectively. Increased blood flow provided by the pump ranged from 2 to 4 L/min. No device-related complications, such as hemolysis, infection, or thromboembolic events, occurred. All patients recovered normal heart function and were weaned from the device. The first patient is well after 12 months. The second patient died of metastatic lymphoma at 2 months, and the third died of Pseudomonas pneumonia after 2 weeks.(ABSTRACT TRUNCATED AT 250 WORDS)","PeriodicalId":77638,"journal":{"name":"The Journal of heart transplantation","volume":"9 4","pages":"408-14"},"PeriodicalIF":0.0,"publicationDate":"1990-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13546126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Registry of the International Society for Heart Transplantation: seventh official report--1990. 国际心脏移植学会登记:第七次官方报告——1990年。

The Journal of heart transplantation Pub Date : 1990-07-01

J M Kriett, M P Kaye

{"title":"The Registry of the International Society for Heart Transplantation: seventh official report--1990.","authors":"J M Kriett, M P Kaye","doi":"","DOIUrl":"","url":null,"abstract":"During the past decade we have witnessed a continuing evolution in intrathoracic transplantation. The role of heart transplantation in end-stage heart disease has been well established; and combined heart-lung and lung transplantation techniques developed during the past 10 years have been applied to an expanding array of diseases associated with end-stage pulmonary failure. Recently a plateau in number of transplants per year has become evident. Although the areas of pediatric heart and single lung transplantation continue to expand, it appears that further overall growth in heart and lung transplantation is now limited by donor availability. Although operative mortality has shown gradual improvement, organ preservation and other intraoperative complications remain major factors associated with early death, especially in combined heart-lung and lung transplantation. Infection and rejection are the most common causes of late deaths for all types of intrathoracic transplantation. Although long-term survival has shown improvement over the past 10 years, an increasing number of patients now require retransplantation because of chronic rejection. Results with heart, combined heart-lung, and lung retransplantation, in operative mortality and in long-term survival, have not been as encouraging as with the primary transplant procedure. We await further developments in heart and lung transplantation during the new decade.","PeriodicalId":77638,"journal":{"name":"The Journal of heart transplantation","volume":"9 4","pages":"323-30"},"PeriodicalIF":0.0,"publicationDate":"1990-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13546268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative trial of immunoprophylaxis with RATG versus OKT3. RATG与OKT3免疫预防的比较研究。

The Journal of heart transplantation Pub Date : 1990-05-01

B P Griffith, R L Kormos, J M Armitage, J S Dummer, R L Hardesty

引用次数: 0

Repair of infected pseudoaneurysm with aortic arch replacement after orthotopic heart transplantation. 原位心脏移植术后主动脉弓置换术修复感染假性动脉瘤。

The Journal of heart transplantation Pub Date : 1990-05-01

A D Slater, B L Ganzel, M Keller, G R Tobin, L A Gray

引用次数: 0