Robyn A. Ellis PhD, Emma Trapani BA, R. Kathryn McHugh PhD
{"title":"Age and gender differences in motives for z-drug misuse: Findings from the 2015 to 2019 NSDUH survey","authors":"Robyn A. Ellis PhD, Emma Trapani BA, R. Kathryn McHugh PhD","doi":"10.1111/ajad.13639","DOIUrl":"10.1111/ajad.13639","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background and Objectives</h3>\u0000 \u0000 <p>Approximately 9% of people who are exposed to a nonbenzodiazepine sedative-hypnotic medication (“z-drug”) misuse this medication, yet, the reasons why people misuse z-drugs are not well-characterized.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Using population survey data, we examined gender and age differences in motives for z-drug misuse.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Results suggested women and older adults have higher odds of misusing z-drugs for sleep, and young adults have higher odds of misusing for recreation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion and Conclusions</h3>\u0000 \u0000 <p>Although the majority of people who misuse z-drugs report misusing to manage sleep, this is particularly common in women and older adults.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Scientific Significance</h3>\u0000 \u0000 <p>Addressing inadequately treated sleep concerns may help mitigate z-drug misuse.</p>\u0000 </section>\u0000 </div>","PeriodicalId":7762,"journal":{"name":"American Journal on Addictions","volume":"33 6","pages":"691-694"},"PeriodicalIF":2.5,"publicationDate":"2024-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141888270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Matthew Johnson DO, MBA, Danielle Cosentino BS, Brian Fuehrlein MD, PhD
{"title":"A detox dilemma beyond benzodiazepines; clonidine's quandary in alcohol withdrawal management","authors":"Matthew Johnson DO, MBA, Danielle Cosentino BS, Brian Fuehrlein MD, PhD","doi":"10.1111/ajad.13640","DOIUrl":"10.1111/ajad.13640","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background and Objectives</h3>\u0000 \u0000 <p>Benzodiazepines are the primary method of treatment of alcohol withdrawal, though the American Society of Addiction Medicine guidelines also include alternative agents for consideration. Observations in a Department of Veterans Affairs (VA) psychiatric emergency room noted consistent benzodiazepine use with an overall lack of use of alternative agents, even with low Clinical Institute Withdrawal Assessment for Alcohol (CIWA) scores and in the absence of other concerning symptoms. Due to concerns of potential more-than-necessary benzodiazepine use, we analyzed adjunctive clonidine use for elevated blood pressure/pulse in alcohol withdrawal among this Veteran population.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This is a single-site VA retrospective chart review of the psychiatric emergency room from July 1, 2022, to June 30, 2023, focused on patients with alcohol withdrawal managed on a CIWA protocol. Excluding concurrent opioid withdrawal and clonidine as home medication, 167 patient charts were analyzed for this study.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Among 167 patients, 99 (59.3%) had comorbid hypertension. A total of 614 medication doses were given for elevated CIWA (373, 60.8%) and elevated blood pressure/pulse (241, 39.2%). Of the 241 doses for elevated blood pressure/pulse, only 2.5% were clonidine. Among all benzodiazepine doses, 75.3% were given to patients with comorbid hypertension. Clonidine was administered to 3.0% of patients, making up 2.5% of total dosing.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion and Conclusions</h3>\u0000 \u0000 <p>Alcohol withdrawal management lacks optimization. Integrating adjunctive medications could reduce potential benzodiazepine overuse effectively addressing elevated blood pressure/pulse.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Scientific Significance</h3>\u0000 \u0000 <p>This study sheds light on the potential underutilization of clonidine and its potential role in improving alcohol withdrawal syndrome management. By addressing elevated blood pressure/pulse and curbing potential overuse of benzodiazepines, it may contribute to further optimizing patient care.</p>\u0000 </section>\u0000 </div>","PeriodicalId":7762,"journal":{"name":"American Journal on Addictions","volume":"34 1","pages":"101-103"},"PeriodicalIF":2.5,"publicationDate":"2024-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141888269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nicholas L. Bormann MD, Andrea N. Weber MD, MME, Tyler S. Oesterle MD, MPH, Benjamin Miskle PharmD, Alison C. Lynch MD, MS, Stephan Arndt PhD
{"title":"State inequities: Gaps in planned treatment for criminal legal referrals with opioid use disorder across two decades of US treatment admissions","authors":"Nicholas L. Bormann MD, Andrea N. Weber MD, MME, Tyler S. Oesterle MD, MPH, Benjamin Miskle PharmD, Alison C. Lynch MD, MS, Stephan Arndt PhD","doi":"10.1111/ajad.13636","DOIUrl":"10.1111/ajad.13636","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background and Objectives</h3>\u0000 \u0000 <p>Criminal-legal (CL) referrals to addiction treatment have historically had low utilization of medications for opioid use disorder (MOUD). While state differences have been reported, an in-depth longitudinal analysis of state-by-state differences is lacking.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The Substance Abuse and Mental Health Services Administration Treatment Episode Dataset-Admissions 2000–2020 provided data for individuals entering their initial treatment with an opioid as their primary substance. Outcome was planned use of MOUD, assessing odds ratio (OR) of CL referrals relative to non-CL referrals cumulatively over the 21-year period and as incremental change (change in relative disparity) using effect sizes, stratified by each state.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>2,187,447 cases met the criteria. Planned MOUD occurred in 37.7% of non-CL clients versus 6.5% of CL clients (OR = 0.11, 95% confidence interval = 0.11–0.12). For all clients, planned MOUD increased from 2000 (33.9%) to 2020 (44.8%). This increase was blunted within CL clients, increasing from 2000 (6.4%) to 2020 (13.3%). Rhode Island saw the greatest improvements in equity.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion and Conclusions</h3>\u0000 \u0000 <p>While rates of planned MOUD increased over the 21 years, a significant disparity persisted among CL clients in most states. As opioid use disorders and opioid-related overdoses are more prevalent among those involved with the CL system, improving this has high impact.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Scientific Significance</h3>\u0000 \u0000 <p>Provides the most comprehensive analysis of state-by-state inequities in MOUD access for CL relative to non-CL referrals over a 21-year period through use of a national data set. Positive outliers are used as case examples for others to follow in pursuit of more equitable care.</p>\u0000 </section>\u0000 </div>","PeriodicalId":7762,"journal":{"name":"American Journal on Addictions","volume":"34 1","pages":"60-68"},"PeriodicalIF":2.5,"publicationDate":"2024-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141888271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Julia D. Buckner PhD, Luke A. Vargo MA, Michael J. Zvolensky PhD
{"title":"Understanding the role of cannabis use on cigarette dependence severity among individuals with e-cigarette and combustible tobacco dual use","authors":"Julia D. Buckner PhD, Luke A. Vargo MA, Michael J. Zvolensky PhD","doi":"10.1111/ajad.13633","DOIUrl":"10.1111/ajad.13633","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background and Objectives</h3>\u0000 \u0000 <p>The use of both electronic and combustible cigarettes is related to greater rates of cannabis use. Further, cannabis use is associated with worse combustible smoking-related outcomes, yet little research has identified mechanisms underlying such relations. It may be that negative-affect-related transdiagnostic factors such as emotion dysregulation, anxiety sensitivity, and/or distress intolerance play a mechanistic role in the cannabis–tobacco interrelations.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The current study tested this hypothesis among 400 adults who endorsed dual use, 33% of whom endorsed current (past 3 months) cannabis use. We conducted analyses of variance and indirect effects model using the PROCESS v4.1 macro in SPSS version 29.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Results indicated that participants who use cannabis reported greater difficulty with emotion regulation, anxiety sensitivity, and cigarette dependence severity. Cannabis use was related to cigarette dependence severity indirectly via difficulty with emotion regulation and anxiety sensitivity.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion and Conclusions</h3>\u0000 \u0000 <p>These results indicate that specific transdiagnostic negative-affect-related factors of difficulty with emotion regulation and anxiety sensitivity are associated with cannabis use among adults who smoke combustible and electronic cigarettes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Scientific Significance</h3>\u0000 \u0000 <p>Given that these transdiagnostic factors are malleable, these findings suggest targeting and engaging such mechanisms may offer novel behavioral change strategies for this high-risk population.</p>\u0000 </section>\u0000 </div>","PeriodicalId":7762,"journal":{"name":"American Journal on Addictions","volume":"33 6","pages":"685-690"},"PeriodicalIF":2.5,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141589409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lilian G. Perez PhD, MPH, Wendy M. Troxel PhD, Joan S. Tucker PhD, Michael S. Dunbar PhD, Anthony Rodriguez PhD, David J. Klein MS, Elizabeth J. D'Amico PhD
{"title":"Discrimination experiences and problematic alcohol and cannabis use in young adulthood","authors":"Lilian G. Perez PhD, MPH, Wendy M. Troxel PhD, Joan S. Tucker PhD, Michael S. Dunbar PhD, Anthony Rodriguez PhD, David J. Klein MS, Elizabeth J. D'Amico PhD","doi":"10.1111/ajad.13632","DOIUrl":"10.1111/ajad.13632","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background and Objectives</h3>\u0000 \u0000 <p>Limited research has examined how discrimination in young adulthood relates to substance use. We examined how multiple and specific types (e.g., race-based) of experiences of unfair treatment are related to problematic alcohol and cannabis use.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We analyzed cross-sectional data from a diverse cohort of young adults (mean age 24.7) predominantly residing in southern California (<i>n</i> = 2303) to examine associations of multiple (count) and specific experiences (race-, sexual orientation-, gender-based) of perceived everyday discrimination with self-reported alcohol and cannabis use outcomes (consequences, use disorders, and solitary use). We also tested interactions between the three specific discrimination experiences and sociodemographic characteristics (e.g., race-based discrimination × race/ethnicity).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>In this diverse sample (e.g., 47% Latinx/o and 22% Asian; 22% sexual/gender diverse; 56% female) of young adults, about 46% reported up to four different discrimination experiences and 27% reported race-, 26% gender-, and 5% sexual orientation-based discrimination. Race- and gender-based discrimination and experiencing more types of discrimination were associated with worse cannabis use outcomes. Race-based discrimination was associated with fewer alcohol consequences and lower Alcohol Use Disorders Identification Test (AUDIT) scores. Associations with sexual orientation-based discrimination and the interactions were not significant.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion and Conclusions</h3>\u0000 \u0000 <p>Findings build on limited research on associations of discrimination with cannabis use in young adults. More work is needed to understand the mechanisms by which discrimination influences drinking behaviors.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Scientific Significance</h3>\u0000 \u0000 <p>This study advances the field by examining the unique contributions of specific and multiple types of discrimination experiences in young adulthood, a critical developmental period in which substance use peaks.</p>\u0000 </section>\u0000 </div>","PeriodicalId":7762,"journal":{"name":"American Journal on Addictions","volume":"34 1","pages":"30-39"},"PeriodicalIF":2.5,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141557864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Call for Special Issue 2024","authors":"","doi":"10.1111/ajad.13623","DOIUrl":"https://doi.org/10.1111/ajad.13623","url":null,"abstract":"<p>Click on the PDF file for live links</p><p></p>","PeriodicalId":7762,"journal":{"name":"American Journal on Addictions","volume":"33 4","pages":"489"},"PeriodicalIF":2.5,"publicationDate":"2024-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ajad.13623","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141441448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"AM Registration Flyer","authors":"","doi":"10.1111/ajad.13628","DOIUrl":"https://doi.org/10.1111/ajad.13628","url":null,"abstract":"<p>Click on the PDF file for live links</p><p></p>","PeriodicalId":7762,"journal":{"name":"American Journal on Addictions","volume":"33 4","pages":"494"},"PeriodicalIF":2.5,"publicationDate":"2024-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ajad.13628","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141441337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Become a AAAP Member","authors":"","doi":"10.1111/ajad.13629","DOIUrl":"https://doi.org/10.1111/ajad.13629","url":null,"abstract":"<p>Click on the PDF file for live links</p><p></p>","PeriodicalId":7762,"journal":{"name":"American Journal on Addictions","volume":"33 4","pages":"495"},"PeriodicalIF":2.5,"publicationDate":"2024-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ajad.13629","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141441447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction to “2024 Annual Meeting Posters”","authors":"","doi":"10.1111/ajad.13618","DOIUrl":"https://doi.org/10.1111/ajad.13618","url":null,"abstract":"<p>2024 Annual Meeting Posters, Am J Addict. 2024;33:167-224. doi:10.1111/ajad.13545.</p><p>When the above “2024 Annual Meeting Posters” were published as part of the 34th AAAP Annual Meeting and Scientific Symposium, several posters were inadvertently not included in the published materials. These missing posters are now included here. We apologize for the error and for any resulting inconvenience incurred.</p>","PeriodicalId":7762,"journal":{"name":"American Journal on Addictions","volume":"33 4","pages":"430-487"},"PeriodicalIF":2.5,"publicationDate":"2024-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ajad.13618","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141441378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Call for Review Papers 2024","authors":"","doi":"10.1111/ajad.13622","DOIUrl":"https://doi.org/10.1111/ajad.13622","url":null,"abstract":"<p>Click on the PDF file for live links</p><p></p>","PeriodicalId":7762,"journal":{"name":"American Journal on Addictions","volume":"33 4","pages":"488"},"PeriodicalIF":2.5,"publicationDate":"2024-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ajad.13622","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141441382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}