Anaesthesiology intensive therapy最新文献

{"title":"Computed tomography measured epicardial adipose tissue and psoas muscle attenuation: new biomarkers to predict major adverse cardiac events (MACE) and mortality in patients with heart disease and critically ill patients. Part I: Epicardial adipose tissue.","authors":"Jeroen Walpot,&nbsp;Paul Van Herck,&nbsp;Caroline M Van de Heyning,&nbsp;Johan Bosmans,&nbsp;Samia Massalha,&nbsp;Manu L N G Malbrain,&nbsp;Hein Heidbuchel,&nbsp;João R Inácio","doi":"10.5114/ait.2023.130922","DOIUrl":"https://doi.org/10.5114/ait.2023.130922","url":null,"abstract":"<p><p>Over the last two decades, the potential role of epicardial adipocyte tissue (EAT) as a marker for major adverse cardiovascular events has been extensively studied. Unlike other visceral adipocyte tissues (VAT), EAT is not separated from the adjacent myocardium by a fascial layer and shares the same microcirculation with the myocardium. Adipocytokines, secreted by EAT, interact directly with the myocardium through paracrine and vasocrine pathways. The role of the Randle cycle, linking VAT accumulation to insulin resistance, and the relevance of blood flow and mitochondrial function of VAT, are briefly discussed. The three available imaging modalities for the assessment of EAT are discussed. The advantages of echocardiography, cardiac CT, and cardiac magnetic resonance (CMR) are compared. The last section summarises the current stage of knowledge on EAT as a clinical marker for major adverse cardiovascular events (MACE). The association between EAT volume and coronary artery disease (CAD) has robustly been validated. There is growing evidence that EAT volume is associated with computed tomography coronary angiography (CTCA) assessed high-risk plaque features. The EAT CT attenuation coefficient predicts coronary events. Many studies have established EAT volume as a predictor of atrial fibrillation after cardiac surgery. Moreover, EAT thickness has been independently associated with severe aortic stenosis and mitral annular calcification. Studies have demonstrated that EAT volume is associated with heart failure. Finally, we discuss the potential role of EAT in critically ill patients admitted to the intensive care unit. In conclusion, EAT seems to be a promising new biomarker to predict MACE.</p>","PeriodicalId":7750,"journal":{"name":"Anaesthesiology intensive therapy","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/db/98/AIT-55-51341.PMC10496106.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41092656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medication errors in the practice of paediatric anaesthesia - a narrative review.","authors":"Neha Goyal,&nbsp;Sugandhi Nemani,&nbsp;Ankur Sharma,&nbsp;Varuna Vyas,&nbsp;Nikhil Kothari,&nbsp;Shilpa Goyal","doi":"10.5114/ait.2023.130837","DOIUrl":"https://doi.org/10.5114/ait.2023.130837","url":null,"abstract":"<p><p>Medication error has emerged as a significant problem in healthcare, especially in the past 2 decades. In anaesthesia, the paediatric age group is particularly at risk of such events because of complex age- and weight-based drug calculation, drug formulations, serial dilutions, and often limited staff experience in handling such patients. We searched PubMed, Cochrane, and Google Scholar for literature on medication errors in paediatric anaesthesia in children (< 18 years of age). Two authors searched for the articles independently, and a third author sorted any consensus differences. A total of 2979 articles were retrieved. We studied primary outcomes, the results, and conclusions of the various studies. A total of 21 relevant articles were selected finally. Following preventive strategies like colour coding, accurate dose calculations, verification by a second individual, and checking and encouraging self-reporting can improve perioperative safety in the paediatric population to a significant extent.</p>","PeriodicalId":7750,"journal":{"name":"Anaesthesiology intensive therapy","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3b/49/AIT-55-51321.PMC10496092.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41092657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of clonidine on heart rate variability during spinal anaesthesia: randomized clinical trial.","authors":"Hermes Melo Teixeira Batista,&nbsp;Solange Kelly Lima Araújo,&nbsp;Galba Matos Cardoso de Alencar Júnior,&nbsp;Luiz Carlos de Abreu,&nbsp;Italla Maria Pinheiro Bezerra,&nbsp;Andrés Ricardo Pérez Riera","doi":"10.5114/ait.2023.130821","DOIUrl":"https://doi.org/10.5114/ait.2023.130821","url":null,"abstract":"<p><strong>Introduction: </strong>Spinal anaesthesia consists of administering a local anaesthetic in the subarachnoid space, thus causing sensory, motor, and autonomic nerve conduction block. Currently, recovery from spinal anaesthesia is evaluated by the return of motor function, without considering the autonomic blockade, which is responsible for most complications of the technique. Heart rate variability (HRV) is an indirect method to measure the autonomic nervous system and may be useful in assessing autonomic recovery after spinal anaesthesia. The study objective was to evaluate the autonomic function, through HRV, at the moment of return of motor function in patients who received spinal anaesthesia when clonidine is used as an adjuvant.</p><p><strong>Material and methods: </strong>This was a randomised, double-blind clinical trial. The sample consisted of 64 ASA I-II patients who underwent spinal anaesthesia and were divided into 2 groups. Group C received 20 mg of bupivacaine with 75 mcg of clonidine, and group B received 20 mg of bupivacaine. HRV was evaluated at rest (T1) and at the time of motor function recovery (T2). Data were collected using a Polar V800® heart rate monitor and then analysed and filtered using Kubios 3.0® software.</p><p><strong>Results: </strong>There was no difference in the values of the low-frequency/high-frequency (LF/HF) ratio, Poincaré plot standard deviation (SD2/SD1), detrended fluctuation analysis (DFAα1, DFAα2), or correlation dimension (D2) indices in any of the groups between the 2 moments. In the clonidine group, there was a difference only in approximate entropy (ApEn), where a P of 0.0124 was obtained considering a 95% confidence interval ranging from 17.83 to 141.47.</p><p><strong>Conclusions: </strong>There was no significant difference between the duration of sympathetic blockade and motor blockade in spinal anaesthesia.</p>","PeriodicalId":7750,"journal":{"name":"Anaesthesiology intensive therapy","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/19/08/AIT-55-51318.PMC10496102.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41098157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dexmedetomidine-induced diabetes insipidus during coronary artery bypass graft surgery.","authors":"Tuan Tang,&nbsp;Rishi Wagle,&nbsp;Jamal Hasoon,&nbsp;Sandeep Markan,&nbsp;Anvinh Nguyen","doi":"10.5114/ait.2023.130859","DOIUrl":"https://doi.org/10.5114/ait.2023.130859","url":null,"abstract":"","PeriodicalId":7750,"journal":{"name":"Anaesthesiology intensive therapy","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c8/f0/AIT-55-51326.PMC10496099.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41099924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intranasal sphenopalatine ganglion block by lignocaine spray for postdural puncture headache following spinal anesthesia: a randomized clinical trial","authors":"Shuchi Smita, Prakash K. Dubey, Kunal Singh","doi":"10.5114/ait.2023.132524","DOIUrl":"https://doi.org/10.5114/ait.2023.132524","url":null,"abstract":"AMA Smita S, Dubey P, Singh K. Intranasal sphenopalatine ganglion block by lignocaine spray for postdural puncture headache following spinal anesthesia: a randomized clinical trial. Anaesthesiology Intensive Therapy. 2023. doi:10.5114/ait.2023.132524. APA Smita, S., Dubey, P., & Singh, K. (2023). Intranasal sphenopalatine ganglion block by lignocaine spray for postdural puncture headache following spinal anesthesia: a randomized clinical trial. Anaesthesiology Intensive Therapy. https://doi.org/10.5114/ait.2023.132524 Chicago Smita, Shuchi, Prakash K. Dubey, and Kunal Singh. 2023. \"Intranasal sphenopalatine ganglion block by lignocaine spray for postdural puncture headache following spinal anesthesia: a randomized clinical trial\". Anaesthesiology Intensive Therapy. doi:10.5114/ait.2023.132524. Harvard Smita, S., Dubey, P., and Singh, K. (2023). Intranasal sphenopalatine ganglion block by lignocaine spray for postdural puncture headache following spinal anesthesia: a randomized clinical trial. Anaesthesiology Intensive Therapy. https://doi.org/10.5114/ait.2023.132524 MLA Smita, Shuchi et al. \"Intranasal sphenopalatine ganglion block by lignocaine spray for postdural puncture headache following spinal anesthesia: a randomized clinical trial.\" Anaesthesiology Intensive Therapy, 2023. doi:10.5114/ait.2023.132524. Vancouver Smita S, Dubey P, Singh K. Intranasal sphenopalatine ganglion block by lignocaine spray for postdural puncture headache following spinal anesthesia: a randomized clinical trial. Anaesthesiology Intensive Therapy. 2023. doi:10.5114/ait.2023.132524.","PeriodicalId":7750,"journal":{"name":"Anaesthesiology intensive therapy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135704696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of Mozart music on patient satisfaction during caesarean delivery: a randomised controlled trial.","authors":"Dan M Drzymalski, Mohammad Dahlawi, Robert R Hall, Shreya Ranjan, Craig L Best","doi":"10.5114/ait.2023.129007","DOIUrl":"10.5114/ait.2023.129007","url":null,"abstract":"<p><strong>Background: </strong>Music is a low-cost intervention that can improve patient satisfaction.</p><p><strong>Methods: </strong>This was a prospective, randomised, controlled trial conducted at an urban tertiary care academic medical centre in the United States. Nulliparous women 18-50 years old with a healthy singleton pregnancy at ≥ 37 weeks gestational age undergoing elective caesarean delivery under neuraxial anaesthesia were randomised to the music group (Mozart sonatas) or control group (no music). Mozart sonatas were broadcast to the music group immediately prior to patient entry and maintained throughout the procedure. The primary outcome was patient satisfaction using the Maternal Satisfaction Scale for Caesarean Section (MSSCS). Secondary outcomes were changes in anxiety pre- and post-operatively and post-operative mean arterial pressure (MAP). Student's t-test, the Wilcoxon rank sum test, and the c2 test were used where appropriate for statistical analyses.</p><p><strong>Results: </strong>27 parturients were evaluated for participation between 2018 and 2019, and 22 enrolled. The final study subject number was 20 due to two withdrawals. There were no clinically meaningful differences in baseline demographics, vital signs, and anxiety. The mean (SD) total patient satisfaction for music vs. control was 116 (16) vs. 120 (22), mean difference 4 (95% CI: -14.0 to 22.0), P = 0.645. The mean (SD) change in anxiety with music vs. control was 2.7 (2.7) vs. 2.5 (2.6), mean difference -0.4 (95% CI: -4.0 to 3.2), P = 0.827. The median (IQR) post-operative MAP with music vs. control was 77.7 (73.7-85.3) vs. 77.3 (72.0-87.3), P = 0.678.</p><p><strong>Conclusions: </strong>The use of Mozart sonatas did not result in improvements in patient satis-faction, anxiety or MAP in parturients undergoing elective caesarean delivery.</p>","PeriodicalId":7750,"journal":{"name":"Anaesthesiology intensive therapy","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/63/b2/AIT-55-50938.PMC10415609.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10071066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing general anaesthesia versus sedation for endoscopic submucosal dissection: results from a systematic review and meta-analysis.","authors":"Choy-May Leung,&nbsp;Rex Wan-Hin Hui","doi":"10.5114/ait.2023.125416","DOIUrl":"https://doi.org/10.5114/ait.2023.125416","url":null,"abstract":"<p><p>Endoscopic submucosal dissection (ESD) is an advanced endoscopic procedure for management of gastrointestinal tumours. ESD is usually performed under sedation. However, the use of general anaesthesia (GA) has been hypothesised to improve ESD outcomes. We performed a systematic review and meta-analysis to compare GA against sedation in ESD. A systematic literature search was performed on Cochrane Library, EMBASE and MEDLINE using the terms \"General Anaesthesia\", \"Sedation\" and \"Endoscopic submucosal dissection\". Original articles comparing GA versus sedation in ESD were included. The risk of bias and level of evidence were assessed by validated methods. This review is registered in PROSPERO (CRD42021275813). 176 articles were found in the initial literature search, and 7 articles (comprising 518 patients receiving GA and 495 receiving sedation) were included. Compared with sedation, GA was associated with higher en-bloc resection rates in oesophageal ESD (RR 1.05; 95% CI: 1.00-1.10; I 2 = 65%; P = 0.05). GA patients also trended towards lower rates of gastrointestinal perforation in all ESD procedures (RR 0.62; 95% CI: 0.21-1.82; I 2 = 52%; P = 0.06). Rates of intra- procedural desaturation and post-procedural aspiration pneumonia were lower in GA patients than in patients under sedation. The included studies had a moderate to high risk of bias, and the overall level of evidence was low. GA appears safe and feasible for ESD, yet high-quality trials will be required before GA can be regularly implemented for ESD.</p>","PeriodicalId":7750,"journal":{"name":"Anaesthesiology intensive therapy","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b7/9d/AIT-55-50200.PMC10156556.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9618031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of positive pressure extubation with traditional extubation in critically ill patients - a randomised control study.","authors":"Ajeetviswanath Thanjavur Prabhakaran,&nbsp;Darlong Vanalal,&nbsp;Kapil Soni,&nbsp;Dalim Baidya,&nbsp;Richa Aggarwal,&nbsp;Harsha Binu,&nbsp;Shivanand Gamanagatti,&nbsp;Maya Dehran,&nbsp;Anjan Trikha","doi":"10.5114/ait.2023.125584","DOIUrl":"https://doi.org/10.5114/ait.2023.125584","url":null,"abstract":"<p><strong>Background: </strong>Two extubation methods are commonly used in the intensive care unit (ICU): the traditional method with endotracheal suctioning and the positive- pressure method without suctioning. Better physiological outcomes were found in lab studies using the latter, as the air passing between the endotracheal tube and the larynx pushes out the collected subglottic secretions, which can be suctioned.</p><p><strong>Methods: </strong>70 mechanically ventilated patients in a tertiary ICU were randomised into 2 groups of 35 patients each. At the end of the spontaneous breathing trial (SBT), the positive pressure extubation (PPE) group was given a pressure support of 15 cm H 2 O and a positive end expiratory pressure of 10 cm H 2 O for 5 minutes while the other group (traditional extubation - TE) was extubated directly. We compared the lung ultrasound scores (LUS), chest X-ray findings, alveolar arterial oxygen gradient changes, adverse clinical events, ICU-free days and reintubation rates between the two groups.</p><p><strong>Results: </strong>Median LUS at the end of the SBT was similar between the two groups. However, the median post-extubation LUS at 30 minutes, 6 hours, 24 hours in the PPE group [5 (4-8) ( P = 0.04), 5 (3-8) ( P = 0.02), 4 (3-7) ( P = 0.02), respectively] were significantly lower compared to the TE group [6 (6-8), 6 (5-7.5), 6 (5-7.5), respectively]. There was a persistent lowering of the scores even at the end of 24 hours in the PPE group, while the percentage of patients without adverse clinical events was significantly higher (80% vs. 57.14%, P = 0.04).</p><p><strong>Conclusions: </strong>The study shows that positive pressure extubation is a safe procedure which improves aeration and reduces adverse events.</p>","PeriodicalId":7750,"journal":{"name":"Anaesthesiology intensive therapy","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7c/bf/AIT-55-50250.PMC10156539.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9618033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commentary: Barotrauma in critically ill patients with COVID-19: miles to go to unwrap the pathophysiology.","authors":"Dipasri Bhattacharya,&nbsp;Mohanchandra Mandal,&nbsp;Antonio Esquinas","doi":"10.5114/ait.2023.126223","DOIUrl":"https://doi.org/10.5114/ait.2023.126223","url":null,"abstract":"Dear Editor, We read with great interest the retrospective case-control study of Venkateswaran et al. [1]. However, we consider that there are certain points that need further clarification, and that the provision of more data in the methodology would make it even more interesting. Firstly, the authors did not mention what flow was used during use of a high-flow nasal cannula (HFNC) for their patients. Lower flow rates (35–40 L min-1) may be advantageous for better patient comfort and initial adaptation, while a higher flow rate (60 L min-1) can provide a faster relief of dyspnoea. One might start with 60 L min-1 and individualise the flow to the highest value tolerated by the patient [2]. The decrease of transoesophageal pressure fluctuations can be used as a measure of patient effort and work of breathing. HFNC may be a fruitful therapy when personalised bedside titration to optimum flow is ensured. Secondly, we are curious to know about the level of positive end-expiratory pressure (PEEP) (the PEEP maximum) used during invasive mechanical ventilation, and whether they utilised any lung-protective strategy and ventilator modes in their cases. Low tidal volume lung protective ventilation remains the cornerstone of supportive therapy in patients with acute respiratory distress syndrome (ARDS), thereby yielding a considerable improvement in outcomes [3]. Higher maximum PEEP has been observed among patients who suffered barotrauma compared with non-barotrauma patients [4]. Finally, in the present study, the authors relied on clinical examination findings and utilised chest radiography, computed tomography, ultrasonography, or a combination thereof to diagnose pneumothorax. It would be interesting to know the details of how many patients were diagnosed using which diagnostic modality. In any study assessing barotrauma, a plausible cause of reported higher incidence of pneumothorax could be the broader use of chest CT with its higher sensitivity to detect extra-alveolar gas collections [5].","PeriodicalId":7750,"journal":{"name":"Anaesthesiology intensive therapy","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c9/d5/AIT-55-50435.PMC10156551.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9625540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prospective, randomised comparison of two intravenous sedation methods for magnetic resonance imaging in children.","authors":"Viktor Mark Brzózka,&nbsp;Andrzej Jerzy Piotrowski","doi":"10.5114/ait.2023.128715","DOIUrl":"https://doi.org/10.5114/ait.2023.128715","url":null,"abstract":"<p><strong>Background: </strong>Children usually need sedation or even anaesthesia for magnetic resonance imaging (MRI) studies. As there is no universally accepted method for this purpose we undertook a prospective, randomised comparison of propofol and dexmedetomidine in children aged 1 to 10 years.</p><p><strong>Methods: </strong>After Institutional Board approval and parents' informed consent 64 ASA status I or II children scheduled for MRI scan were enrolled. Patients were premedicated with intravenous (IV) midazolam (0.1 mg kg -1 ) and ketamine (1 mg kg -1 ) and randomised to propofol (P) or dexmedetomidine (D) group. A propofol bolus of 1 mg kg -1 followed by infusion of 4 mg kg -1 h -1 , or dexmedetomidine 1 µg kg -1 followed by 2 µg kg -1 h-1 infusion were used. Heart rate, SpO 2 and non-invasive blood pressure were monitored and recorded at 5 min intervals. Results were compared by means of standard statistical methods.</p><p><strong>Results: </strong>Both dexmedetomidine and propofol after premedication with ketamine and midazolam are suitable for MRI sedation, although propofol use results in shorter recovery time. Less interventions are needed when dexmedetomidine is used.</p>","PeriodicalId":7750,"journal":{"name":"Anaesthesiology intensive therapy","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/96/99/AIT-55-50864.PMC10415600.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10446666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}