Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism最新文献_第4页

Adolescent alcohol drinking and its long-range consequences. Studies with animal models. 青少年饮酒及其长期后果。动物模型研究。

Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism Pub Date : 2005-01-01 DOI: 10.1007/0-306-48626-1_6

William J McBride, Richard L Bell, Zachary A Rodd, Wendy N Strother, James M Murphy

{"title":"Adolescent alcohol drinking and its long-range consequences. Studies with animal models.","authors":"William J McBride, Richard L Bell, Zachary A Rodd, Wendy N Strother, James M Murphy","doi":"10.1007/0-306-48626-1_6","DOIUrl":"https://doi.org/10.1007/0-306-48626-1_6","url":null,"abstract":"This chapter reviews findings, mainly obtained from the selectively bred alcohol-preferring (P) line of rats, on (a) the development of alcohol drinking during the peri-adolescent period, (b) neurobiological factors that may contribute to adolescent drinking, (c) interventions to prevent alcohol drinking during adolescence, and (d) some long-lasting consequences of adolescent alcohol drinking. The findings indicate that P rats readily initiate alcohol drinking during the early post-weaning, adolescent and peri-adolescent periods of development. The early age-of-onset of alcohol drinking in the P compared to the NP line is associated with (a) higher densities of serotonin-1A (5-HT1A) receptors in cerebral cortical and hippocampal regions; (b) lower densities of dopamine (DA) D2 receptors in the ventral tegmental area (VTA); (c) higher functional activity in several limbic, cortical and hippocampal regions; and (d) sensitivity to the low-dose stimulating effect of ethanol. Conditioned taste aversion (CTA) training during adolescence produces long-term effects on preventing high alcohol drinking behavior of P rats. Alcohol drinking during peri-adolescence by P rats produces long-lasting effects that increase the acquisition of ethanol self-administration in adulthood, and, in addition, increase craving-like behavior and the potential for alcohol relapse. With suitable animal models, a better understanding of the mechanisms underlying adolescent alcohol drinking and its long-range consequences can be attained.","PeriodicalId":77344,"journal":{"name":"Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism","volume":"17 ","pages":"123-42"},"PeriodicalIF":0.0,"publicationDate":"2005-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/0-306-48626-1_6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25022914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 51

Comprehensive approaches to prevent adolescent drinking and related problems. 采取综合措施预防青少年饮酒及相关问题。

Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism Pub Date : 2005-01-01 DOI: 10.1007/0-306-48626-1_10

Kelli A Komro, Melissa H Stigler, Cheryl L Perry

引用次数: 11

Prevention of adolescent alcohol problems in special populations. 在特殊人群中预防青少年酗酒问题。

Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism Pub Date : 2005-01-01 DOI: 10.1007/0-306-48626-1_11

Steve Sussman

引用次数: 10

Policies to reduce underage drinking. A review of the recent literature. 减少未成年人饮酒的政策。近期文献综述。

Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism Pub Date : 2005-01-01

Alexander C Wagenaar, Kathleen M Lenk, Traci L Toomey

引用次数: 0

Prevention for children of alcoholics and other high risk groups. 预防酗酒儿童和其他高危人群。

Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism Pub Date : 2005-01-01 DOI: 10.1007/0-306-48626-1_14

Robert A Zucker, Maria M Wong

引用次数: 34

A brief history and some current dimensions of adolescent treatment in the United States. 美国青少年治疗的简史和现状。

Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism Pub Date : 2005-01-01 DOI: 10.1007/0-306-48626-1_17

Mark D Godley, William L White

{"title":"A brief history and some current dimensions of adolescent treatment in the United States.","authors":"Mark D Godley, William L White","doi":"10.1007/0-306-48626-1_17","DOIUrl":"https://doi.org/10.1007/0-306-48626-1_17","url":null,"abstract":"Resources for the treatment of adolescent substance use disorders have increased over the past century in tandem with the increased visibility and cultural alarm regarding adolescent substance-related problems. The United States now has a multi-branched and growing system of adolescent treatment services that spans public and private sectors and offers services in both specialty and non-specialty service settings. Most adolescents are entering treatment due to alcohol and/or cannabis-related problems (and, to a lesser degree, other illicit drugs), but present with a wide array of co-occurring problems and obstacles to recovery. Multiple levels of specialized care are available but most adolescents being treated via outpatient counseling. The number and methodological rigor of adolescent treatment outcome studies have increased dramatically in recent years. The findings of these studies suggest the need for earlier systems of problem identification and intervention, a model of sustained recovery support for adolescents presenting with high problem severity and complexity, and sustained interventions with the adolescent's post-treatment family and social environment. In the opening decade of the twenty-first century, the treatment of adolescent substance use disorders is itself maturing into a professionalized and science-guided service arena.","PeriodicalId":77344,"journal":{"name":"Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism","volume":"17 ","pages":"367-82"},"PeriodicalIF":0.0,"publicationDate":"2005-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/0-306-48626-1_17","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25024060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 17

Assessment issues in adolescent drug abuse treatment research. 青少年药物滥用治疗研究中的评估问题。

Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism Pub Date : 2005-01-01 DOI: 10.1007/0-306-48626-1_19

Ken Winters, Tamara Fahnhorst

引用次数: 10

Diagnosis, course, and assessment of alcohol abuse and dependence in adolescents. 青少年酒精滥用和依赖的诊断、过程和评估。

Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism Pub Date : 2005-01-01 DOI: 10.1007/0-306-48626-1_1

Tammy Chung, Christopher S Martin, Ken C Winters

引用次数: 40

Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism Pub Date : 2005-01-01 DOI: 10.1007/0-306-48626-1_8

Aaron M White, H Scott Swartzwelder

{"title":"Age-related effects of alcohol on memory and memory-related brain function in adolescents and adults.","authors":"Aaron M White, H Scott Swartzwelder","doi":"10.1007/0-306-48626-1_8","DOIUrl":"https://doi.org/10.1007/0-306-48626-1_8","url":null,"abstract":"As detailed in this brief review, there is now clear evidence that adolescence represents a unique stage of brain development. Changes in brain organization and function during adolescence are widespread, and include intense rewiring in the frontal lobes and other neorcortical regions, as well as changes in a litany of subcortical structures. Recent research suggests that, because of these changes in brain function, drugs like alcohol affect adolescents and adults differently. The available evidence, much of it from research with animal models, suggests that adolescents might be more sensitive than adults to the memory impairing effects of alcohol, as well as the impact of alcohol on the brain function that underlies memory formation. For instance, when treated with alcohol, adolescent rats perform worse than adults in spatial learning tasks that are known to require the functioning of the hippocampus. Alcohol disrupts hippocampal function, and does so more potently in adolescents than adults. In contrast, adolescents appear to be far less sensitive than adults to both the sedative and motor impairing effects of alcohol. While research on this topic is still in its infancy, the findings clearly suggest that adolescence represents a unique stage of sensitivity to the impact of alcohol on behavior and brain function.","PeriodicalId":77344,"journal":{"name":"Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism","volume":"17 ","pages":"161-76"},"PeriodicalIF":0.0,"publicationDate":"2005-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/0-306-48626-1_8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25024051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 164

Treatment of adolescent alcohol-related problems. A translational perspective. 治疗青少年酒精相关问题。翻译视角。

Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism Pub Date : 2005-01-01 DOI: 10.1007/0-306-48626-1_15

Sandra A Brown, Kristen G Anderson, Danielle E Ramo, Kristin L Tomlinson

{"title":"Treatment of adolescent alcohol-related problems. A translational perspective.","authors":"Sandra A Brown, Kristen G Anderson, Danielle E Ramo, Kristin L Tomlinson","doi":"10.1007/0-306-48626-1_15","DOIUrl":"https://doi.org/10.1007/0-306-48626-1_15","url":null,"abstract":"In the present chapter we have sought to articulate a translational perspective linking development during adolescence to alcohol treatment and its evaluation. Clearly adolescents with alcohol use disorders cannot be treated as younger versions of adults. The unique demands of their developmental stage permeate all aspects of their behavior, including alcohol use and abuse. Multi-dimensional developmental models help inform the design, implementation, and evaluation of alcohol and drug treatment programs. While an understanding of individual risk factors is informative, only through models integrating multiple risk pathways embedded in the context of adolescent development can we hope to build more efficacious and effective systems of intervention for youth with AUDs. Effective treatment of adolescent AUDs not only urges translation of the developmental perspective into pre-existing treatment approaches but argues for a paradigm shift towards alternative intervention designs and evaluation procedures and foci.","PeriodicalId":77344,"journal":{"name":"Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism","volume":"17 ","pages":"327-48"},"PeriodicalIF":0.0,"publicationDate":"2005-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/0-306-48626-1_15","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25024058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11