Abduraimov S. Ozodbek, Shomurodov F. Habibullo, Beshko Yu. Natalya, Maxmudov V. Azizbek, Mavlanov J. Bekzod, Allamurotov L. Akmal, Sharipova K. Vasila, Mamatkasimov T. Odilbek, Abduraimov S. Azizbek, Giyasiddinov L. Abduaziz
{"title":"Ecological Analysis of Species of the Genus <i>Ferula</i> L., Distributed in Navoi Region (Uzbekistan)","authors":"Abduraimov S. Ozodbek, Shomurodov F. Habibullo, Beshko Yu. Natalya, Maxmudov V. Azizbek, Mavlanov J. Bekzod, Allamurotov L. Akmal, Sharipova K. Vasila, Mamatkasimov T. Odilbek, Abduraimov S. Azizbek, Giyasiddinov L. Abduaziz","doi":"10.4236/ajps.2023.1411085","DOIUrl":"https://doi.org/10.4236/ajps.2023.1411085","url":null,"abstract":"Ferula L. is a perennial herbaceous plant belonging to the family Apiaceae Lindl. (Umbelliferae). Our research was carried out on the territory of Navoi region. The article presents an ecological analysis of the species of the Ferula L. in Navoi region. The species of genus Ferula mostly grows in mountainous regions and some are distributed in arid climates. According to that 15 species of the genus were found in the Navoi region, most of these species are considered to be plants that contain tar as well as have a strong medicinal property. In various parts of the world, different species of Ferula have been used in traditional medicine. In the course of studies, it was found that the species has medicinal, essential-oil, honey-juicy, nutritious, and fodder properties. According to ecological analysis, the genus Ferula grows Rocky, gravelly, fine-grained slopes and ridges of mountains, scree, rocks, outcrops of variegated rocks, rocky slopes, sandy, clay and gravelly deserts, foothill plains, fine-grained slopes. Considered rare, Ferula kyzylkumica Korovin is listed in the Red Book of the Republic of Uzbekistan, while Ferula nuratavica Pimenov is an endemic plant of the Aktau ridge.","PeriodicalId":7726,"journal":{"name":"American Journal of Plant Sciences","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135711602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Flavonoids and Amino Acids Analysis of the Fruits of <i>Cornus mas</i> L. Introduced in Uzbekistan","authors":"Gulnaz Matkarimova, Nodira Nurullayeva, Khislat Khaydarov","doi":"10.4236/ajps.2023.149073","DOIUrl":"https://doi.org/10.4236/ajps.2023.149073","url":null,"abstract":"Cornelian cherry is used in the food and pharmaceutical industry as an ornament, in traditional medicine, and in the manufacture of household items. It is widely used in medicine for the prevention and treatment of many diseases. Therefore, it is important to research the chemical composition of these species. In the article, based on our research, the analysis of the quantitative calculation of flavonoids and amino acids of the fruits of the “Elegant” and “Svetlyachok” cherry varieties was carried out. It was found that the amount of amino acids in the fruits of Cornus mas L., introduced in Uzbekistan, is higher in the variety “Svetlyachok” 2.643235 mg/g. In “Elegant” variety it was 1.794235 mg/g. The amount of 4 different flavonoids in the fruit was also determined. It has been established that the Elegant variety has a high concentration of lutein and rutin, and the svetlyachok has a high concentration of apigenin and quercetin.","PeriodicalId":7726,"journal":{"name":"American Journal of Plant Sciences","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135799120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Valeriya Navrotskaya, Gregory Oxenkrug, Lyudmila Vorobyova, Paul Summergrad
{"title":"Berberine Attenuated Aging-Accelerating Effect of High Temperature in Drosophila Model.","authors":"Valeriya Navrotskaya, Gregory Oxenkrug, Lyudmila Vorobyova, Paul Summergrad","doi":"10.4236/ajps.2014.53037","DOIUrl":"https://doi.org/10.4236/ajps.2014.53037","url":null,"abstract":"<p><p>We have observed that berberine prolonged life span and improved viability of pupae and climbing activity of imagoes of wild-type Drosophila melanogaster maintained at 23°C. As a continuation of our studies of berberine effect on life span, we were interested to evaluate the effect of berberine of life span in flies maintained at a higher temperature (28°C) known to accelerate aging in wild type flies. Considering that genetically or pharmacologically induced deficiency of TRP conversion into KYN prolonged life span in a Drosophila model, we compared the effects of berberine, a powerful inhibitor of kynurenine (KYN) formation from tryptophan (TRP), on life span in wild type and in Drosophila melanogaster mutants (vermilion) with deficient TRP-KYN metabolism maintained at 23°C and 28°C. High (28°C) ambient temperature decreased life span in both wild type and vermilion flies. Aging accelerating effect of high temperature was more pronounced in Oregon than in vermilion flies (-60% vs. -40% decrease of mean life span, resp). Berberine attenuated the aging-accelerating effect of high temperature. Effect of berberine was more pronounced in Oregon (+46%) than in vermilion (+22%) flies. The obtained data suggested the possible involvement of TRP-KYN metabolism in the aging-acceleration effect of the high temperature and in protective effect of berberine.</p>","PeriodicalId":7726,"journal":{"name":"American Journal of Plant Sciences","volume":"5 3","pages":"275-278"},"PeriodicalIF":0.0,"publicationDate":"2014-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498585/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33898358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V V Navrotskaya, G Oxenkrug, L I Vorobyova, P Summergrad
{"title":"Berberine Prolongs Life Span and Stimulates Locomotor Activity of <i>Drosophila melanogaster</i>.","authors":"V V Navrotskaya, G Oxenkrug, L I Vorobyova, P Summergrad","doi":"10.4236/ajps.2012.327123","DOIUrl":"https://doi.org/10.4236/ajps.2012.327123","url":null,"abstract":"<p><p><i>Drosophila melanogaster</i> mutants with deficient kynurenine (KYN) formation from tryptophan (TRP) have longer life span than wild type flies. Administration of alpha-methyl-TRP and 5-methyl-TRY, the inhibitors of TRP-KYN metabolism, prolonged life span in wild-type flies. Both inhibitors are not available for human use. Berberine, an isoquinoline alkaloid isolated from <i>Berberis aristata</i>, is known as the herb widely used in traditional Chinese and Indian medicine. Berberin is a strong inhibitor of the enzyme catalyzing TRP conversion into KYN. Considering this particular feature we investigated the effect of berberine on life- and health-span in wild-type <i>Drosophila melanogaster</i>. The results of our study showed that Berberine extended mean, median and maximum life span of female flies. Berberine did not affect the number of pupae of filial generation and decreased their lethality. Berberine increased locomotor activity (vertical climbing). The results of the study suggest that berberine prolongs life- and improves health-span of <i>Drosophila melanogaster</i>. Berberine might be a candidate drug for prevention and treatment of aging and aging-associated medical and psychiatric disorders.</p>","PeriodicalId":7726,"journal":{"name":"American Journal of Plant Sciences","volume":"3 7A","pages":"1037-1040"},"PeriodicalIF":0.0,"publicationDate":"2012-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4236/ajps.2012.327123","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33898357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}