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Metabolic, pediatric, and systemic ophthalmology (New York, N.Y. : 1985)最新文献

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Optic neuropathies: therapeutic approach. 视神经病变:治疗方法。
Metabolic, pediatric, and systemic ophthalmology (New York, N.Y. : 1985) Pub Date : 1990-01-01
M T Dorigo, F Moro
{"title":"Optic neuropathies: therapeutic approach.","authors":"M T Dorigo,&nbsp;F Moro","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The review deals with therapeutic aspects of optic nerve diseases. Attention is given to the lack of established guidelines for treatment of different optic neuropathies. In fact, there are no sure protocols in the literature for infective, inflammatory and vascular disorders. The authors present some new drugs and discuss the efficacy of related therapy, in particular for vascular disorders. The differentiated therapy for arteritic and non-arteritic AION is discussed. Treatment of vascular occlusion in the acute phase, in the post-occlusive state and prophylaxis is reported. The usefulness of anticoagulants is examined. In the conclusion, the authors stress the necessity to carry out properly controlled multicenter trials to obtain valid knowledge that allows rational and effective therapy protocols.</p>","PeriodicalId":77261,"journal":{"name":"Metabolic, pediatric, and systemic ophthalmology (New York, N.Y. : 1985)","volume":"13 2-4","pages":"106-10"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13122558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Red cell reduced glutathione and tobacco smoke-induced optic neuropathy. 红细胞减少谷胱甘肽与烟草烟雾诱导的视神经病变。
Metabolic, pediatric, and systemic ophthalmology (New York, N.Y. : 1985) Pub Date : 1990-01-01
C Costagliola, L Cotticelli, M Menzione, M Rinaldi, S Russo, E Rinaldi
{"title":"Red cell reduced glutathione and tobacco smoke-induced optic neuropathy.","authors":"C Costagliola,&nbsp;L Cotticelli,&nbsp;M Menzione,&nbsp;M Rinaldi,&nbsp;S Russo,&nbsp;E Rinaldi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Cigarette smoke contains detectable amounts of cyanide, regardless of the type of cigarette. The very high levels of this compound in plasma of amblyopic smokers suggests that cyanide causes optic neuropathy. The detoxification of cyanide in man occurs through various metabolic pathway; the most important are those that use sulfur to transform cyanide into thiocyanate. One of the richest sources of reduced sulfhydryl groups is reduced glutathione (GSH). For this reason we investigated red cell GSH levels in non-smokers, in healthy smokers and in smokers affected by optic neuropathy to ascertain whether this compound is a marker of the disease. Red cell GSH levels in the non-smokers group were similar to those of affected smokers. On the contrary, GSH levels in healthy smokers were significantly more elevated. During therapy with vitamin E we noted that the concentration of GSH decreased with the progression of the disease and increased with recovery. Moreover, there was a good correlation between GSH levels and clinical findings. Our findings demonstrate that GSH plays a key role in the detoxification of cyanide and so it could be a marker of tobacco smoke-induced optic neuropathy.</p>","PeriodicalId":77261,"journal":{"name":"Metabolic, pediatric, and systemic ophthalmology (New York, N.Y. : 1985)","volume":"13 2-4","pages":"96-8"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13236061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Occult ocular damage as a leading sign in the battered child syndrome. 隐蔽性眼损伤是受虐儿童综合征的主要症状。
Metabolic, pediatric, and systemic ophthalmology (New York, N.Y. : 1985) Pub Date : 1990-01-01
I Levy, Y S Wysenbeek, M Nitzan, I Nissenkorn, T Lerman-Sagle, R Steinherz
{"title":"Occult ocular damage as a leading sign in the battered child syndrome.","authors":"I Levy,&nbsp;Y S Wysenbeek,&nbsp;M Nitzan,&nbsp;I Nissenkorn,&nbsp;T Lerman-Sagle,&nbsp;R Steinherz","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A three-month old, premature female infant is presented with severe bilateral occult ocular damage comprised of cataracts, lenses dislocation, retinal hemorrhages and total funnel-shaped retinal detachment without external signs such as bruises. This severe eye trauma is the result of child abuse. We would like to alert pediatricians as well as ophthalmologists that any ocular injury should raise the possible diagnosis of battered child syndrome even in the absence of other supportive evidence of external trauma.</p>","PeriodicalId":77261,"journal":{"name":"Metabolic, pediatric, and systemic ophthalmology (New York, N.Y. : 1985)","volume":"13 1","pages":"20-2"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13519584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optic nerve head drusen: histopathological considerations--clinical features. 视神经头水肿:组织病理学考虑-临床特征。
Metabolic, pediatric, and systemic ophthalmology (New York, N.Y. : 1985) Pub Date : 1990-01-01
L Giarelli, G Ravalico, S Saviano, A Grandi
{"title":"Optic nerve head drusen: histopathological considerations--clinical features.","authors":"L Giarelli,&nbsp;G Ravalico,&nbsp;S Saviano,&nbsp;A Grandi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The histopathological features made on 18 autopsies have proved that the optic nerve head drusen are calcified formations situated within the margins of the optic nerve head. It has been supposed that not only an aberrant axoplasmic transport, but also the presence of local factors, partly depending on the Bruch's membrane, can play a determining role in the pathogenesis of the optic disc drusen. A spongiotic edema gives us the histopathological equivalent of the clinical aspect of the optic disc with indistinct margins and lack of the central cup and furthermore gives us an explanation about the perimetric alterations pathogenesis. Clinical observations confirm that the optic nerve head drusen are prevalently asymptomatic and that visual acuity remains unchanged. The threshold tests are able to quantify exactly the entity and the depth of the visual field defects and its possible changing within a certain period of time. As regards the diagnosis, the retinal fluoroangiography is of great importance allowing to distinguish clearly a pseudo-papillary edema from a papillary edema.</p>","PeriodicalId":77261,"journal":{"name":"Metabolic, pediatric, and systemic ophthalmology (New York, N.Y. : 1985)","volume":"13 2-4","pages":"88-91"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13236059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Contribution of manual and computerized perimetry to the differential diagnosis of optic neuropathies. 人工和计算机视野检查对视神经病变鉴别诊断的贡献。
Metabolic, pediatric, and systemic ophthalmology (New York, N.Y. : 1985) Pub Date : 1990-01-01
M Zingirian, M T Dorigo, E Gandolfo
{"title":"Contribution of manual and computerized perimetry to the differential diagnosis of optic neuropathies.","authors":"M Zingirian,&nbsp;M T Dorigo,&nbsp;E Gandolfo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The contribution given by manual perimetry to differential diagnosis of optic neuropathies is described. The advantages and the disadvantages of automated perimetry in respect to manual perimetry are examined. The programs to use for a more precise diagnosis and according to different pathology are also examined. The problems connected to perimetric interpretation are discussed. The value of global indices in evaluating the visual field as well as the importance of statistical program in comparing more than one test performed are reported. The review stresses the usefulness of automated perimetry in early diagnosis and in the follow up of optic nerve diseases.</p>","PeriodicalId":77261,"journal":{"name":"Metabolic, pediatric, and systemic ophthalmology (New York, N.Y. : 1985)","volume":"13 2-4","pages":"50-4"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13235505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tumors of the optic nerve. 视神经肿瘤。
Metabolic, pediatric, and systemic ophthalmology (New York, N.Y. : 1985) Pub Date : 1990-01-01
F C Blodi
{"title":"Tumors of the optic nerve.","authors":"F C Blodi","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77261,"journal":{"name":"Metabolic, pediatric, and systemic ophthalmology (New York, N.Y. : 1985)","volume":"13 2-4","pages":"47-9"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13235504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of retinoblastoma: a preliminary report of a modified approach. 视网膜母细胞瘤的治疗:一种改良方法的初步报告。
Metabolic, pediatric, and systemic ophthalmology (New York, N.Y. : 1985) Pub Date : 1990-01-01
A el Massri
{"title":"Treatment of retinoblastoma: a preliminary report of a modified approach.","authors":"A el Massri","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Overdosage of radiation in the treatment of retinoblastoma is agreed upon as the main cause of chorioretinopathic complications and is due to following the conventional empirical dosages blindly. A clinical assessment is substituted and a lower dose proved effective and prevention or at least minimizing the degree of complications is achieved.</p>","PeriodicalId":77261,"journal":{"name":"Metabolic, pediatric, and systemic ophthalmology (New York, N.Y. : 1985)","volume":"13 1","pages":"10-4"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13519581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of fluorescein angiography in the interpretation of optic nerve head diseases. 荧光素血管造影在视神经头疾病诊断中的作用。
Metabolic, pediatric, and systemic ophthalmology (New York, N.Y. : 1985) Pub Date : 1990-01-01
T Segato, S Piermarocchi, E Midena
{"title":"The role of fluorescein angiography in the interpretation of optic nerve head diseases.","authors":"T Segato,&nbsp;S Piermarocchi,&nbsp;E Midena","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In normal individuals fluorescein angiography of the optic nerve head has some peculiar signs. Three early phases can be distinguished, they include: 1) retrolaminar and laminar filling, 2) prelaminar filling, 3) superficial capillary filling. A late staining is also part of the fluorescein angiography of a normal disc. Many optic nerve disturbances show changes of the above mentioned angiographic signs. The Authors discuss the fluorescein angiographic pattern of 1) anterior ischemic optic neuropathy, 2) central retinal vein occlusion, 3) papilledema and 4) drusen.</p>","PeriodicalId":77261,"journal":{"name":"Metabolic, pediatric, and systemic ophthalmology (New York, N.Y. : 1985)","volume":"13 2-4","pages":"111-4"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13235501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ischemic optic neuropathies. 缺血性视神经病变。
Metabolic, pediatric, and systemic ophthalmology (New York, N.Y. : 1985) Pub Date : 1990-01-01
F Moro, D Doro, E Mantovani, M Sala
{"title":"Ischemic optic neuropathies.","authors":"F Moro,&nbsp;D Doro,&nbsp;E Mantovani,&nbsp;M Sala","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Primary or secondary impairment of blood supply to the optic nerve results in a spectrum of ischemic optic neuropathies with multiple etiopathogenesis. Among these the clinical features of traumatic and radiation optic neuropathy are outlined. Diagnostic criteria, associated conditions, risk factors and functional prognosis of anterior ischemic optic neuropathy are reviewed and discussed in the light of the contribution of recent literature.</p>","PeriodicalId":77261,"journal":{"name":"Metabolic, pediatric, and systemic ophthalmology (New York, N.Y. : 1985)","volume":"13 2-4","pages":"75-8"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13236056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The optic nerve. Padua, Italy, November 1988. 视神经。1988年11月，意大利帕多瓦。
Metabolic, pediatric, and systemic ophthalmology (New York, N.Y. : 1985) Pub Date : 1990-01-01
{"title":"The optic nerve. Padua, Italy, November 1988.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77261,"journal":{"name":"Metabolic, pediatric, and systemic ophthalmology (New York, N.Y. : 1985)","volume":"13 2-4","pages":"45-128"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13140929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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