Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians最新文献_第10页

Invasive techniques for prenatal diagnosis: current concepts. 产前诊断的侵入性技术:当前概念。

Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians Pub Date : 1995-01-01

R O Bahado-Singh, R Morotti, J Pirhonen, J A Copel, M J Mahoney

引用次数: 0

Variations in oral glucose tolerance tests: the 100- versus 75-g controversy. 口服葡萄糖耐量试验的变化:100克与75克之争

Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians Pub Date : 1995-01-01

L E Brustman, B D Gela, M Moore, K D Reilly, O Langer

引用次数: 0

Management of tuberculosis in pregnancy. 妊娠期结核病的管理。

Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians Pub Date : 1995-01-01

C E Henderson

引用次数: 0

Hypertension: a multietiological disease requires a multifactorial approach. 高血压：一种多病因疾病，需要采用多因素方法。

Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians Pub Date : 1995-01-01

B W Trotman

引用次数: 0

Impact of an inner-city, hospital-based preterm prevention program on preterm births in twin gestation. 市中心医院早产儿预防项目对双胎早产的影响

Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians Pub Date : 1995-01-01

C F Edwards, C Chazotte, M C Freda, L Shah, B Girz, K Damus, I R Merkatz

{"title":"Impact of an inner-city, hospital-based preterm prevention program on preterm births in twin gestation.","authors":"C F Edwards, C Chazotte, M C Freda, L Shah, B Girz, K Damus, I R Merkatz","doi":"","DOIUrl":"","url":null,"abstract":"The objective of this study was to determine the impact of an inner-city, hospital-based preterm-birth prevention program on the outcome of twin pregnancies. A retrospective study of delivery outcomes from 1985 to 1992 of eligible consecutive twin deliveries that were > or = 20 weeks' gestation compared two inner-city hospitals in the Bronx, New York: one with a preterm prevention program for twin births and a comparable site offering conventional prenatal care. A group of patients receiving no prenatal care was also included. Outcomes were evaluated by prenatal-care site, except for those who received no prenatal care and delivered at either site. Data were analyzed by chi-square analysis and analysis of variance. Of the 377 twin pregnancies, 330 pregnancies were eligible deliveries. One hundred thirty-four women received prenatal care from the preterm prevention program, 161 received conventional prenatal care at a comparable site, and 35 received no prenatal care. Maternal age, parity, and mode of delivery were similar in the two delivery sites. There was an increased incidence of complications in the no-prenatal-care group compared with the groups who received the preterm prevention or conventional prenatal care. The percentage of low-birth-weight (< 2500 g) and very-low-birth-weight (< 1000 g) infants was similar in the preterm prevention and the conventional care groups. The percentage of extremely low-birth-weight (< 1000 g) infants was significantly lower in twin births of the preterm prevention site (9.7%) and the conventional site (11.3%) compared with the no-prenatal-care group (28.6%) (P < .01).(ABSTRACT TRUNCATED AT 250 WORDS)","PeriodicalId":77227,"journal":{"name":"Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians","volume":"6 2","pages":"78-81"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18775960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular analysis of genetic diseases: an overview for clinicians. 遗传疾病的分子分析:临床医生综述。

Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians Pub Date : 1995-01-01

A A Javed, Y Huang, A T Bombard

{"title":"Molecular analysis of genetic diseases: an overview for clinicians.","authors":"A A Javed, Y Huang, A T Bombard","doi":"","DOIUrl":"","url":null,"abstract":"The identification of fetal genetic disease has, for the most part, relied on examination of an end product, such as analysis of factor VIII levels obtained from cord blood in fetuses at risk for hemophilia. Advances in molecular genetics have shifted our focus in prenatal diagnosis away from protein product analysis toward etiology, making new discoveries gleaned from the Human Genome Project relevant to clinicians. This review discusses the basic principles involved in gene-based diagnosis, highlighting the complexities of current approaches to molecular diagnosis of fetal genetic disease. Given an understanding of both the theory and practice of genetic analysis, the review covers the fundamental principles of molecular biology (structure, function, packaging, and regulation) and discusses recombinant DNA techniques presently used for the analysis of mutations. Clinical examples are presented to introduce the techniques most commonly employed in service laboratories: direct detection assays, where the specific mutation is recognized, and indirect detection assays, useful for the deduction of an inheritance pattern where the actual mutation or its gene is not known but may be closely linked to known DNA polymorphisms.","PeriodicalId":77227,"journal":{"name":"Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians","volume":"6 1","pages":"15-27"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18857675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Accuracy and precision of serum gastrin measurements in commercial laboratories. 商业实验室血清胃泌素测定的准确性和精密度。

Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians Pub Date : 1995-01-01

V Notar-Francesco, S Samuel, S Kanakamedala, E W Straus

{"title":"Accuracy and precision of serum gastrin measurements in commercial laboratories.","authors":"V Notar-Francesco, S Samuel, S Kanakamedala, E W Straus","doi":"","DOIUrl":"","url":null,"abstract":"Patients referred to us with \"positive\" secretin tests and the diagnosis of Zollinger-Ellison syndrome were found to be achlorhydric. This observation led us to study prospectively the accuracy and precision of serum gastrin determinations from commercial laboratories. Synthetic gastrin (G17) was added to serum to achieve gastrin concentrations of 50, 100, 250, 500, 750, 1000, 3000, and 5000 pg/mL after subtraction of the basal value (24 pg/mL). Three aliquots of each concentration were analyzed by radioimmunoassay in our laboratory (Health Science Center at Brooklyn) and sent to four major commercial laboratories that perform 5000 to 25,000 gastrin assays per year. The reported gastrin concentrations of the triplicate samples demonstrate that many commercial laboratories failed to accurately measure gastrin. Commercial laboratories generally reported higher-than-actual gastrin concentrations in samples containing less than 500 pg/mL and lower-than-actual gastrin concentrations in samples containing more than 500 pg/mL. Of all aliquots containing 100 pg/mL or less, 14 of 24 samples (58%) were reported by commercial laboratories to contain elevated gastrin concentrations. At gastrin concentrations from 250 to 5000 pg/mL, the range of values (highest- to lowest-reported value for each concentration) was greater than 200 pg/mL in 62% of triplicate samples reported by commercial laboratories. These data indicate that determinations by some commercial laboratories lack the precision required to satisfy the current diagnostic criterion (a postsecretin rise from basal gastrin of 200 pg/mL or greater) for Zollinger-Ellison syndrome. Clinicians should be aware of this problem and obtain more basal serum gastrin samples to allow for an analysis of the range of baseline values prior to secretin injection.","PeriodicalId":77227,"journal":{"name":"Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians","volume":"6 4","pages":"130-3"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19500488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gastric erosions induced by nonsteroidal anti-inflammatory drugs: clinical significance, pathogenesis, and therapeutic perspectives. 非甾体抗炎药引起的胃糜烂:临床意义、发病机制和治疗前景。

Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians Pub Date : 1995-01-01

N M Agrawal, K Aziz

引用次数: 0

Cultural diversity as a factor in self-monitoring blood glucose in gestational diabetes. 文化多样性是妊娠糖尿病患者自我监测血糖的一个因素。

Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians Pub Date : 1995-01-01

O Langer, N Langer, J M Piper, B Elliott, A Anyaegbunam

{"title":"Cultural diversity as a factor in self-monitoring blood glucose in gestational diabetes.","authors":"O Langer, N Langer, J M Piper, B Elliott, A Anyaegbunam","doi":"","DOIUrl":"","url":null,"abstract":"The routine use of self-monitoring of capillary blood glucose by pregnant diabetic patients currently provides the basis for both clinical management and ongoing investigation. Strategies must therefore be developed to ensure that these data are reliable and accurately reported by patients and are not influenced by diverse socioeconomic levels or varied geographic locations. To explore this issue, we used glucose reflectance meters with a memory microchip capable of storing up to 440 consecutive blood glucose determinations. Two diverse groups of women from Texas and New York who had gestational diabetes performed self-monitoring of blood glucose from diagnosis until delivery. Both groups recorded their blood glucose results daily in a logbook. The reporting performance of all the participating subjects resulted in an actual compliance rate of 60% to 70% of testings required of the patients. Comparison of African-American, Mexican-American, and white populations revealed no significant differences in patient performance or compliance. Moreover, no differences were found between the groups at different geographic locations (New York, Texas) in patients' willingness and ability to comply with the regimen of self-monitoring blood glucose. These findings suggest that the use of memory reflectance meters, in conjunction with patient education and positive interaction between patient and care provider, will result in high patient compliance regardless of socioeconomic level or ethnic diversity.","PeriodicalId":77227,"journal":{"name":"Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians","volume":"6 2","pages":"73-7"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18775959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lipid profile in women with preeclampsia: relationship between plasma triglyceride levels and severity of preeclampsia. 子痫前期妇女血脂:血浆甘油三酯水平与子痫前期严重程度的关系

Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians Pub Date : 1995-01-01

M S Mikhail, J Basu, P R Palan, J Furgiuele, S L Romney, A Anyaegbunam

引用次数: 0