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The Role of Protein Oxidative Modification and the Cellular Redox Status in Realization of Apoptosis of MCF-7 Breast Adenocarcmoma Cells. 蛋白氧化修饰和细胞氧化还原在MCF-7乳腺腺癌细胞凋亡中的作用
Izvestiia Akademii nauk. Seriia biologicheskaia Pub Date : 2016-09-01
E V Shakhristova, E A Stepovaya, N V Ryazantseva, O L Nosareva, V D Yakushina, V V Ivanov, V V Novitsky
{"title":"The Role of Protein Oxidative Modification and the Cellular Redox Status in Realization of Apoptosis of MCF-7 Breast Adenocarcmoma Cells.","authors":"E V Shakhristova,&nbsp;E A Stepovaya,&nbsp;N V Ryazantseva,&nbsp;O L Nosareva,&nbsp;V D Yakushina,&nbsp;V V Ivanov,&nbsp;V V Novitsky","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The aim of this study was to establish the role of redox modification of proteins and redox status in the realization of apoptosis of MCF-7 breast adenocarcinoma cells du-ing cultivation with the SH-group blocker N-ethylmaleimide (NEM) and the SH-group protector 1,4-dithioerythritol (DTE). The activation of apoptosis in MCF-7 breast adenocarcinoma cells was shown to be due to the irreversible modification of redox sensitive protein molecules. The presence of DTE in the culture medium of cancer.cells caused reversible glutathionylation of protein molecules and did not change the: number of apoptotic MCF-7 cells.</p>","PeriodicalId":77187,"journal":{"name":"Izvestiia Akademii nauk. Seriia biologicheskaia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36499006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Irregularity of the Linear Growth of the Margaritifera margaritifera (Bivalvia: Margaritiferidae) Population of the Nemina River, Karelia. 卡累利阿涅米纳河玛格丽特种群线性生长的不规则性(双壳目:玛格丽特科)
Izvestiia Akademii nauk. Seriia biologicheskaia Pub Date : 2016-07-01
A A Zotin, E P Ieshko
{"title":"Irregularity of the Linear Growth of the Margaritifera margaritifera (Bivalvia: Margaritiferidae) Population of the Nemina River, Karelia.","authors":"A A Zotin,&nbsp;E P Ieshko","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The dependence of shell growth in length and height during ontogeny has been studied in the pearl mussel Margaritifera margaritifera inhabiting the Nemina River (basin of Lake Onega, Karelia). It has been shown that the population is heterogenous based on the height-to-length ratio. It has been found that during ontogeny M. margaritifera from the studied population undergoes a constant change in the relative growth of the shell leading to either lengthening or rounding of the shell.</p>","PeriodicalId":77187,"journal":{"name":"Izvestiia Akademii nauk. Seriia biologicheskaia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36520651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Primary Plant Successions of Forest Belt Vegetation on the Tolbachinskii Dol Volcanic Plateau (Kamchatka). 堪察加托尔巴钦斯基火山高原林带植被的原始植物演替
Izvestiia Akademii nauk. Seriia biologicheskaia Pub Date : 2016-07-01
A P Korablev, V Yu Neshataeva
{"title":"Primary Plant Successions of Forest Belt Vegetation on the Tolbachinskii Dol Volcanic Plateau (Kamchatka).","authors":"A P Korablev,&nbsp;V Yu Neshataeva","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Primary plant successions on volcanic deposits of the Tolbachinskii DoI Plateau (Central Kamchatka) were studied. The main factors determining the succession rate were revealed. The peculiarities of plant successions on lava flows and ash-scoria deposits differed significantly. Some common mechanisms for all volcanic regions of the world were revealed. The leading factors of plant succession on lava flows were the type of lava surface, the texture of lava, and the fine tephra accumulation rate. The main factors determining plant succession on ash-scoria deposits were wind and water erosion and the distance to the seed sources. The time of formation of a secondary permanent larch (Larix cajanderi Mayr.) forest should take about 1500-2000 years on lava flows and up to 1000 years (but not less than 300-500 years) on ash-scoria plains.</p>","PeriodicalId":77187,"journal":{"name":"Izvestiia Akademii nauk. Seriia biologicheskaia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36520645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mitotypical Peculiarities of the Population of Moose Alces alces of Southeastern West Siberia. 西伯利亚西部东南部驼鹿种群的有丝分裂特征。
Izvestiia Akademii nauk. Seriia biologicheskaia Pub Date : 2016-07-01
O V Nemoikina, M V Kholodova, O Yu Tyutenkov, N S Moskvitina
{"title":"Mitotypical Peculiarities of the Population of Moose Alces alces of Southeastern West Siberia.","authors":"O V Nemoikina,&nbsp;M V Kholodova,&nbsp;O Yu Tyutenkov,&nbsp;N S Moskvitina","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Based on the structure of the D-loop control region of mitochondrial DNA, the genetic diversity of moose of West Siberia was evaluated and their placement within the structure of current species population was determined. It was noted that the values of genetic diversity exceed the values of analogous indices obtained for western groups of the species. Three haplogroups were identified in the population structure: European- Ural, West Siberian, and American.</p>","PeriodicalId":77187,"journal":{"name":"Izvestiia Akademii nauk. Seriia biologicheskaia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36520648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Suppression of Histamine-Induced Relaxation of Rat Aorta and Calcium Signaling in Endothelial Cells by Two-Pore Channel Blocker trans-NED19 and Hydrogen Peroxide. 双孔通道阻滞剂反式ned19和过氧化氢抑制组胺诱导的大鼠主动脉舒张和内皮细胞钙信号。
Izvestiia Akademii nauk. Seriia biologicheskaia Pub Date : 2016-07-01
I L Zharkich, A D Nadeev, E B Tsitrin, N V Goncharov, P V Avdonin
{"title":"Suppression of Histamine-Induced Relaxation of Rat Aorta and Calcium Signaling in Endothelial Cells by Two-Pore Channel Blocker trans-NED19 and Hydrogen Peroxide.","authors":"I L Zharkich,&nbsp;A D Nadeev,&nbsp;E B Tsitrin,&nbsp;N V Goncharov,&nbsp;P V Avdonin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The blocker of two-pore channels trans-NED 19 and hydrogen peroxide were found to inhibit histamine-induced relaxation of rat-aorta. The degree of inhibition depended on histamine concentration. The relaxation in response to I μM histamine of rat aorta preconstricted with 30 mM KCI, serotonin, or endothelin- 1, was completely abolished by 30 μM trans-NED 19. On the other hand, trans-NED 19 decreased the relaxation of the aorta in the presence of 10 μM histamine only by 2.1-fold to 2.4-fold, and there was almost no inhibition by trans-NED 19 of the relaxationinduced by 100 ptM histamine.) Relaxation of precontracted with serotonin aorta in response to 10 and 100 μM histamine was reduced by hydrogen peroxide (200 M) by 10- and 2.5-fold, respectively. Suppression of aorta relaxation by trans-NED 19 and H202 correlated with their inhibitory effect on the histamine-induced increase in the cytoplasmic free calcium concentration in human umbilical vein endothelial cells. With the use of a fluorescent probe LysoTracker, the cis-NED19 binding sites were demonstrated to be localized in endolysosomes of the endothelial cells. These data indicate that two-pore calcium channels participate in the histamine-induced endothelium-dependent relaxation of rat aorta. Furthermore, their functional role is exhibited much more clearly at low histamine concentrations. We suggest that hydrogen peroxide evokes depletion of intracellular calcium depots thereby suppressing the response to histamine.</p>","PeriodicalId":77187,"journal":{"name":"Izvestiia Akademii nauk. Seriia biologicheskaia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36520652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changes in the Composition and Physiological and Biochemical Properties of Fungi during Passage through the Digestive Tract of Earthworms. 真菌在蚯蚓消化道中的组成及生理生化特性的变化。
Izvestiia Akademii nauk. Seriia biologicheskaia Pub Date : 2016-07-01
A V Kurakov, S A Kharin, B A Byzov
{"title":"Changes in the Composition and Physiological and Biochemical Properties of Fungi during Passage through the Digestive Tract of Earthworms.","authors":"A V Kurakov,&nbsp;S A Kharin,&nbsp;B A Byzov","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>It was established that the biomass of fungal mycelium decreased by 30-50% during passage through the in- testine of the Aporrectodea caliginosa and Lumbricus terrestris earthworms, while its content in empty intes- tines was 40-60% less than in the soil. It was found that the amount of mycelium increases again in three-day-old coprolites due to the rapid growth of the species. It was demonstrated that the physiological activity of fungi (estimated according to the time of the appearance of colonies on the medium and probability of propagation) is lower in the intestine content, digestive tract, and fresh excrement of the worms than in the soil. It was noted that the activity and diversity of organic substrates (utilized by fungi), as well as proteolytic activity is lower in fungal isolates from the intestine than from the soil. It was registered that the death of a part of the fungi occurs in the worm intestine, while the physiological state changes in the animals withstanding the effect of the digestive medium.</p>","PeriodicalId":77187,"journal":{"name":"Izvestiia Akademii nauk. Seriia biologicheskaia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36520643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pine Wilt Disease and Possible Causes of Its Incidence in Russia. 俄罗斯松树萎蔫病及其可能的发病原因。
Izvestiia Akademii nauk. Seriia biologicheskaia Pub Date : 2016-07-01
E N Arbuzova, O A Kulinich, E S Mazurin, A Yu Ryss, N I Kozyreva, S V Zinovieva
{"title":"Pine Wilt Disease and Possible Causes of Its Incidence in Russia.","authors":"E N Arbuzova,&nbsp;O A Kulinich,&nbsp;E S Mazurin,&nbsp;A Yu Ryss,&nbsp;N I Kozyreva,&nbsp;S V Zinovieva","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Surveys of forests and stockpiled timber of pine, spruce, larch, and silver fir in 14 administrative subjects of the Russian Federation revealed widespread occurrence of the coniferous wood parasitic nematode Bursaphelenchus mucronatus. Twenty species of bacteria belonging to 13 genera have been detected in 25 B. mucronatus isolates, and their identity has been determined by direct sequencing of the 16S- RNA gene. The most frequently occurring were bacteria from the genera Pseudomonas, -Stenotrophomonas, Pantoea, Bacillus, Burkholderia, and Serratia. Prevalence of Pseudomonas brenneri and P. fluorescence, which were also found in the nematode dauer larva (Liv) isolated from the fir sawyer beetle Monochamus urussovi, have also been assessed. Two nematode B. xylophilus isolates from Portugal and one isolate from the United States have been examined, and 10 symbiotic bacteria species have been isolated, including Agrobacterium tumefacience, P.fluorescens, P. brenneri, Rahnella aquatilis, Stenotrophomonas maltophilia, S. rhizophila, and Yersinia mollaretfi.</p>","PeriodicalId":77187,"journal":{"name":"Izvestiia Akademii nauk. Seriia biologicheskaia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36520644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effect of Commercial Cuttings on Faunal Associations in Taiga Ecosystems: A Case Study of Small Mammals in Eastern Fennoscandia. 商业插枝对针叶林生态系统动物群落的影响——以芬诺斯坎迪亚东部小型哺乳动物为例
Izvestiia Akademii nauk. Seriia biologicheskaia Pub Date : 2016-07-01
E V Ivanter, Yu P Kurkhinen
{"title":"The Effect of Commercial Cuttings on Faunal Associations in Taiga Ecosystems: A Case Study of Small Mammals in Eastern Fennoscandia.","authors":"E V Ivanter,&nbsp;Yu P Kurkhinen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The general patterns of the effect of cuttings on the habitat structure, abundance, territorial distribution, and specific ecological features of 11 small mammalian species are analyzed based on long-term studies (1958-2013) covering the overall area of eastern Fennoscandia. The responses to concentrated cuttings common for most of the examined species include a decrease in total population size, transition to an- arrhythmic population dynamics with drastic short-term rises and deep long depressions, formation of unstable mosaic spatial distribution, disturbances of the reproduction rates, and a decrease in reproduction intensity.</p>","PeriodicalId":77187,"journal":{"name":"Izvestiia Akademii nauk. Seriia biologicheskaia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36520649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Seasonal Changes in Blood Cells and Biochemical Parameters in the Mongolian Hamster (Allocricetulus curtatus). 蒙古仓鼠(Allocricetulus curtatus)血细胞和生化指标的季节变化。
Izvestiia Akademii nauk. Seriia biologicheskaia Pub Date : 2016-07-01
E V Kuznetsova, N Y Feoktistova, S V Naidenko, A V Surov, N B Tikhonova, Ju E Kozlovskii
{"title":"Seasonal Changes in Blood Cells and Biochemical Parameters in the Mongolian Hamster (Allocricetulus curtatus).","authors":"E V Kuznetsova,&nbsp;N Y Feoktistova,&nbsp;S V Naidenko,&nbsp;A V Surov,&nbsp;N B Tikhonova,&nbsp;Ju E Kozlovskii","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>It was shown previously that the Mongolian hamster (Allocricetulus curtatus) is a mammalian species with irregular short hibernation. The purpose of the present study was to determine how this status affects seasonal changes in the biochemical and hematological parameters in A. curtatus males under a natural temperature and light regime. It was found that a reduction in circulating white blood cells, specifically lymphocytes, neutrophils, eosinophils, basophils, and monocytes, occurred in-winter. and bilirubin levels increased in spring. These characteristics make Mongolian hamsters closer to the true hibernating species. At the same time, the character of seasonal changes in the number of red blood cells, glucose, total protein, creatinine, and albumin is closer to species with torpor.</p>","PeriodicalId":77187,"journal":{"name":"Izvestiia Akademii nauk. Seriia biologicheskaia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36520650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Diversity of Parasites in the Chinese Sleeper Perccottus glenii Dybowski 1877 (Actinopterygii: Perciformes) under the Conditions of Large-Scale Range Expansion. 大规模活动范围扩大条件下中国卧蚊(actinopterygi_perciformes)寄生生物多样性研究。
Izvestiia Akademii nauk. Seriia biologicheskaia Pub Date : 2016-07-01
S G Sokolov, A V Zhukov
{"title":"The Diversity of Parasites in the Chinese Sleeper Perccottus glenii Dybowski 1877 (Actinopterygii: Perciformes) under the Conditions of Large-Scale Range Expansion.","authors":"S G Sokolov,&nbsp;A V Zhukov","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>It has been found that the species composition of parasites infesting the Chinese sleeper Perccottus glenii in water bodies from the nonnative part of its range is more depleted. Here, the phylogenetic distances between parasites exceed those in the native part of the range. It has been revealed that parasitological differences between P. glenii populations from the nonnative and native parts of the range, as well as between populations inside the nonnative part, have similar composition and abundance of the host-specific and euryxenous components in the parasitic fauna. It has been shown that these differences are determined by the genesis of sites from which P. glenii is introduced, as well as the local conditions of the recipient water bodies.</p>","PeriodicalId":77187,"journal":{"name":"Izvestiia Akademii nauk. Seriia biologicheskaia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36519110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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