Important advances in oncology最新文献

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The multidrug resistance phenotype in human cancer. 人类癌症的多药耐药表型。
Important advances in oncology Pub Date : 1991-01-01
C Cordon-Cardo, J P O'Brien
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引用次数: 0
Is a mechanism such as the NCI's Clinical Alert ever an appropriate alternative to journal peer review? 像NCI的临床预警这样的机制是期刊同行评议的合适替代吗?
Important advances in oncology Pub Date : 1991-01-01
V T DeVita
{"title":"Is a mechanism such as the NCI's Clinical Alert ever an appropriate alternative to journal peer review?","authors":"V T DeVita","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Responsibly handled, a mechanism such as a Clinical Alert can provide physicians with enough information to deal with the early release of data to the public. The journal peer review system was established primarily as an academic tool to allow publication of scientific work for the purpose of communicating information among scientists and physicians. Since both the number of papers published by an investigator and the quality of the journal publishing them are important to academic advancement, bypassing this system naturally threatens many physicians and scientists. The Clinical Alert, however, served its purpose and was well received by the majority of practicing physicians and the public. In fact, a second Alert was issued by NCI in October 1989 when data became available on the effectiveness of a new adjuvant drug therapy for a common stage of colon cancer (Appendix B) and, at a workshop convened by the National Cancer Advisory Board, where the mechanism of the Clinical Alerts was discussed, it was apparent that most participants felt that maintaining this process was important. In light of the current revolution in biology, the public's interest in receiving the benefits of its financial support of the national research enterprise, and access by the press to both scientific literature and meetings, it seems appropriate for public officials, especially when mandated by Congress, to take the responsibility of releasing some types of data to the public before traditional peer review. Some visible public decision-making process must, however, be used where the pros and cons of early release of a particular data set can be discussed, as was done with the original NCI Clinical Alert.(ABSTRACT TRUNCATED AT 250 WORDS)</p>","PeriodicalId":77172,"journal":{"name":"Important advances in oncology","volume":" ","pages":"241-54"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13029253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Potential innovations in scheduling of cancer chemotherapy. 癌症化疗计划的潜在创新。
Important advances in oncology Pub Date : 1991-01-01
L Norton, R Day
{"title":"Potential innovations in scheduling of cancer chemotherapy.","authors":"L Norton,&nbsp;R Day","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77172,"journal":{"name":"Important advances in oncology","volume":" ","pages":"57-72"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13029256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of the human papillomavirus oncoproteins in transformation and carcinogenic progression. 人乳头瘤病毒癌蛋白在转化和致癌进展中的作用。
Important advances in oncology Pub Date : 1991-01-01
B A Werness, K Münger, P M Howley
{"title":"Role of the human papillomavirus oncoproteins in transformation and carcinogenic progression.","authors":"B A Werness,&nbsp;K Münger,&nbsp;P M Howley","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77172,"journal":{"name":"Important advances in oncology","volume":" ","pages":"3-18"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12816964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genetic predisposition to cancer. 癌症的遗传易感性。
Important advances in oncology Pub Date : 1991-01-01
L A Cannon-Albright, D T Bishop, C Goldgar, M H Skolnick
{"title":"Genetic predisposition to cancer.","authors":"L A Cannon-Albright,&nbsp;D T Bishop,&nbsp;C Goldgar,&nbsp;M H Skolnick","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77172,"journal":{"name":"Important advances in oncology","volume":" ","pages":"39-55"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13029255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cellular and molecular aspects of human tumor radioresistance. 人类肿瘤放射抵抗的细胞和分子方面。
Important advances in oncology Pub Date : 1991-01-01
R R Weichselbaum
{"title":"Cellular and molecular aspects of human tumor radioresistance.","authors":"R R Weichselbaum","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77172,"journal":{"name":"Important advances in oncology","volume":" ","pages":"73-83"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13029257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Colony-stimulating factors: clinical status. 集落刺激因素:临床状况。
Important advances in oncology Pub Date : 1991-01-01
J L Gabrilove
{"title":"Colony-stimulating factors: clinical status.","authors":"J L Gabrilove","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77172,"journal":{"name":"Important advances in oncology","volume":" ","pages":"215-37"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12878313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular and cellular mechanisms of angiogenesis. 血管生成的分子和细胞机制。
Important advances in oncology Pub Date : 1990-01-01
T Maciag
{"title":"Molecular and cellular mechanisms of angiogenesis.","authors":"T Maciag","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77172,"journal":{"name":"Important advances in oncology","volume":" ","pages":"85-98"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12855817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CHOP chemotherapy as standard therapy for treatment of patients with diffuse histiocytic lymphoma. CHOP化疗作为弥漫性组织细胞淋巴瘤患者的标准治疗方案。
Important advances in oncology Pub Date : 1990-01-01
R I Fisher
{"title":"CHOP chemotherapy as standard therapy for treatment of patients with diffuse histiocytic lymphoma.","authors":"R I Fisher","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77172,"journal":{"name":"Important advances in oncology","volume":" ","pages":"217-25"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13336990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular genetics of lymphoproliferative processes. 淋巴增生过程的分子遗传学。
Important advances in oncology Pub Date : 1990-01-01
J Cossman, M Stetler-Stevenson, L J Medeiros, M Raffeld
{"title":"Molecular genetics of lymphoproliferative processes.","authors":"J Cossman,&nbsp;M Stetler-Stevenson,&nbsp;L J Medeiros,&nbsp;M Raffeld","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77172,"journal":{"name":"Important advances in oncology","volume":" ","pages":"101-13"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13336984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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