HPB surgery : a world journal of hepatic, pancreatic and biliary surgery最新文献_第4页

The Surgical Management of Concomitant Gallbladder and Common Bile Duct Stones. 胆囊结石及胆总管结石的外科治疗。

HPB surgery : a world journal of hepatic, pancreatic and biliary surgery Pub Date : 2015-01-01 Epub Date: 2015-09-01 DOI: 10.1155/2015/165068

J H Darrien, K Connor, A Janeczko, J J Casey, S Paterson-Brown

{"title":"The Surgical Management of Concomitant Gallbladder and Common Bile Duct Stones.","authors":"J H Darrien, K Connor, A Janeczko, J J Casey, S Paterson-Brown","doi":"10.1155/2015/165068","DOIUrl":"https://doi.org/10.1155/2015/165068","url":null,"abstract":"Background. The management of choledocholithiasis has evolved from open common bile duct exploration (OCBDE) to therapeutic endoscopic retrograde cholangiopancreatography (ERCP) to laparoscopic common bile duct exploration (LCBDE). Each entails a degree of difficulty. Aim. To review 5-year results of bile duct exploration in an UGI unit. Methods. Common bile duct explorations (CBDEs) performed between January 2008 and January 2013 were identified from a prospectively collected clinical audit system and results reviewed retrospectively. Results. 216 CBDEs were performed, 119 (55%) as an emergency and 52 (24%) following failed ERCP. Open CBDE (OCBDE) was performed primarily in 34/216 (16%) patients and attempted laparoscopically in 182 (84%). Fifty nine (32%) Laparoscopic CBDEs (LCBDEs) were converted to OCBDE. Of the remaining 123 LCBDEs, 51 (41%) primary choledochotomies and 72 (59%) primary transcystic CBDEs (TC-CBDEs) were performed. Forty nine (68%) TC-CBDEs were considered successful and 23 (32%) failed. Fifteen failed TC-CBDEs were converted to a successful laparoscopic choledochotomy. Ductal clearance was achieved in 187/216 (87%) patients and retained stones were identified in 20/123 (16%) LCBDEs. Complications occurred in 52/216 (24%) patients. There were 8/216 (4%) bile leaks requiring further intervention. Postoperative ERCP was carried out in 32/216 (15%) patients and 9/216 (4%) required relaparoscopy/laparotomy. No patient died. Conclusions. Successful management of choledocholithiasis requires a breadth of laparoscopic and endoscopic expertise. ","PeriodicalId":77165,"journal":{"name":"HPB surgery : a world journal of hepatic, pancreatic and biliary surgery","volume":"2015 ","pages":"165068"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2015/165068","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34115673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 19

Surgical strategy for isolated caudate lobectomy: experience with 16 cases. 孤立性尾状叶切除术的手术策略:附16例体会。

HPB surgery : a world journal of hepatic, pancreatic and biliary surgery Pub Date : 2014-01-01 Epub Date: 2014-07-01 DOI: 10.1155/2014/983684

Gendong Tian, Qiong Chen, Yuan Guo, Mujian Teng, Jie Li

{"title":"Surgical strategy for isolated caudate lobectomy: experience with 16 cases.","authors":"Gendong Tian, Qiong Chen, Yuan Guo, Mujian Teng, Jie Li","doi":"10.1155/2014/983684","DOIUrl":"https://doi.org/10.1155/2014/983684","url":null,"abstract":"Introduction. Surgical resection is the most effective treatment for neoplasm in the caudate lobe. Isolated caudate lobectomy is still a challenge for hepatobiliary surgeons. No widely accepted surgical strategy for the procedure has been developed yet. Objective. To get a better understanding of isolated caudate lobectomy and to optimize the procedure. Materials and Methods. 16 cases of isolated caudate lobectomy were reviewed to summarize the surgical experience. Results. All the 16 cases of isolated caudate lobectomy were carried out successfully, among which left side approach was adopted in two cases (12.5%), right side approach in three cases (18.75%), and both sides approach in 11 cases (68.75%). No severe complications occurred. Conclusion. The majority of neoplasms confined to the caudate lobe can be resected safely by left and right side approach with proper anatomic surgical procedure, usually in the sequence of mobilization, outflow control, inflow control, and division of the hepatic parenchyma. Fully mobilizing the caudate lobe from the inferior vena cava (IVC) is of great importance. Division of the retrohepatic ligament and the venous ligament facilitated the procedure. ","PeriodicalId":77165,"journal":{"name":"HPB surgery : a world journal of hepatic, pancreatic and biliary surgery","volume":"2014 ","pages":"983684"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/983684","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32566954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

The prognostic significance of lymphatics in colorectal liver metastases. 淋巴在结直肠肝转移中的预后意义。

HPB surgery : a world journal of hepatic, pancreatic and biliary surgery Pub Date : 2014-01-01 Epub Date: 2014-05-20 DOI: 10.1155/2014/954604

Vijayaragavan Muralidharan, Linh Nguyen, Jonathan Banting, Christopher Christophi

{"title":"The prognostic significance of lymphatics in colorectal liver metastases.","authors":"Vijayaragavan Muralidharan, Linh Nguyen, Jonathan Banting, Christopher Christophi","doi":"10.1155/2014/954604","DOIUrl":"https://doi.org/10.1155/2014/954604","url":null,"abstract":"Background. Colorectal Cancer (CRC) is the most common form of cancer diagnosed in Australia across both genders. Approximately, 40%-60% of patients with CRC develop metastasis, the liver being the most common site. Almost 70% of CRC mortality can be attributed to the development of liver metastasis. This study examines the pattern and density of lymphatics in colorectal liver metastases (CLM) as predictors of survival following hepatic resection for CLM. Methods. Patient tissue samples were obtained from the Victorian Cancer Biobank. Immunohistochemistry was used to examine the spatial differences in blood and lymphatic vessel densities between different regions within the tumor (CLM) and surrounding host tissue. Lymphatic vessel density (LVD) was assessed as a potential prognostic marker. Results. Patients with low lymphatic vessel density in the tumor centre, tumor periphery, and adjacent normal liver demonstrated a significant disease-free survival advantage compared to patients with high lymphatic vessel density (P = 0.01, P > 0.01, and P = 0.05, resp.). Lymphatic vessel density in the tumor centre and periphery and adjacent normal liver was an accurate predictive marker of disease-free survival (P = 0.05). Conclusion. Lymphatic vessel density in CLM appears to be an accurate predictor of recurrence and disease-free survival. ","PeriodicalId":77165,"journal":{"name":"HPB surgery : a world journal of hepatic, pancreatic and biliary surgery","volume":"2014 ","pages":"954604"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/954604","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32454718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Liver resections of isolated liver metastasis in breast cancer: results and possible prognostic factors. 乳腺癌分离性肝转移的肝切除:结果和可能的预后因素。

HPB surgery : a world journal of hepatic, pancreatic and biliary surgery Pub Date : 2014-01-01 Epub Date: 2014-01-19 DOI: 10.1155/2014/893829

Malte Weinrich, Christel Weiß, Jochen Schuld, Bettina M Rau

{"title":"Liver resections of isolated liver metastasis in breast cancer: results and possible prognostic factors.","authors":"Malte Weinrich, Christel Weiß, Jochen Schuld, Bettina M Rau","doi":"10.1155/2014/893829","DOIUrl":"https://doi.org/10.1155/2014/893829","url":null,"abstract":"Background. Breast cancer liver metastasis is a hematogenous spread of the primary tumour. It can, however, be the expression of an isolated recurrence. Surgical resection is often possible but controversial. Methods. We report on 29 female patients treated operatively due to isolated breast cancer liver metastasis over a period of six years. Prior to surgery all metastases appeared resectable. Liver metastasis had been diagnosed 55 (median, range 1-177) months after primary surgery. Results. Complete resection of the metastases was performed in 21 cases. The intraoperative staging did not confirm the preoperative radiological findings in 14 cases, which did not generally lead to inoperability. One-year survival rate was 86% in resected patients and 37.5% in nonresected patients. Significant prognostic factors were R0 resection, low T- and N-stages as well as a low-grade histopathology of the primary tumour, lower number of liver metastases, and a longer time interval between primary surgery and the occurrence of liver metastasis. Conclusions. Complete resection of metastases was possible in three-quarters of the patients. Some of the studied factors showed a prognostic value and therefore might influence indication for resection in the future. ","PeriodicalId":77165,"journal":{"name":"HPB surgery : a world journal of hepatic, pancreatic and biliary surgery","volume":"2014 ","pages":"893829"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/893829","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32139898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 34

Preoperative gadoxetic Acid-enhanced MRI and simultaneous treatment of early hepatocellular carcinoma prolonged recurrence-free survival of progressed hepatocellular carcinoma patients after hepatic resection. 术前加多西酸增强MRI和同时治疗早期肝癌延长进展期肝癌患者肝切除术后无复发生存期。

HPB surgery : a world journal of hepatic, pancreatic and biliary surgery Pub Date : 2014-01-01 Epub Date: 2014-02-19 DOI: 10.1155/2014/641685

Masanori Matsuda, Tomoaki Ichikawa, Hidetake Amemiya, Akira Maki, Mitsuaki Watanabe, Hiromichi Kawaida, Hiroshi Kono, Katsuhiro Sano, Utaroh Motosugi, Hideki Fujii

{"title":"Preoperative gadoxetic Acid-enhanced MRI and simultaneous treatment of early hepatocellular carcinoma prolonged recurrence-free survival of progressed hepatocellular carcinoma patients after hepatic resection.","authors":"Masanori Matsuda, Tomoaki Ichikawa, Hidetake Amemiya, Akira Maki, Mitsuaki Watanabe, Hiromichi Kawaida, Hiroshi Kono, Katsuhiro Sano, Utaroh Motosugi, Hideki Fujii","doi":"10.1155/2014/641685","DOIUrl":"https://doi.org/10.1155/2014/641685","url":null,"abstract":"Background/Purpose. The purpose of this study was to clarify whether preoperative gadoxetic acid-enhanced magnetic resonance imaging (EOB-MRI) and simultaneous treatment of suspected early hepatocellular carcinoma (eHCC) at the time of resection for progressed HCC affected patient prognosis following hepatic resection. Methods. A total of 147 consecutive patients who underwent their first curative hepatic resection for progressed HCC were enrolled. Of these, 77 patients underwent EOB-MRI (EOB-MRI (+)) before hepatic resection and the remaining 70 patients did not (EOB-MRI (-)). Suspected eHCCs detected by preoperative imaging were resected or ablated at the time of resection for progressed HCC. Results. The number of patients who underwent treatment for eHCCs was significantly higher in the EOB-MRI (+) than in the EOB-MRI (-) (17 versus 6; P = 0.04). Recurrence-free survival (1-, 3-, and 5-year; 81.4, 62.6, 48.7% versus 82.1, 41.5, 25.5%, resp., P < 0.01), but not overall survival (1-, 3-, and 5-year; 98.7, 90.7, 80.8% versus 97.0, 86.3, 72.4%, resp., P = 0.38), was significantly better in the EOB-MRI (+). Univariate and multivariate analyses showed that preoperative EOB-MRI was one of the independent factors significantly correlated with better recurrence-free survival. Conclusions. Preoperative EOB-MRI and simultaneous treatment of eHCC prolonged recurrence-free survival after hepatic resection. ","PeriodicalId":77165,"journal":{"name":"HPB surgery : a world journal of hepatic, pancreatic and biliary surgery","volume":"2014 ","pages":"641685"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/641685","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32236462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 23

Combined liver and multivisceral resections. 肝及多脏器联合切除。

HPB surgery : a world journal of hepatic, pancreatic and biliary surgery Pub Date : 2014-01-01 Epub Date: 2014-02-11 DOI: 10.1155/2014/976546

Martin de Santibañes, Agustin Dietrich, Eduardo de Santibañes

引用次数: 2

The Interaction between Diabetes, Body Mass Index, Hepatic Steatosis, and Risk of Liver Resection: Insulin Dependent Diabetes Is the Greatest Risk for Major Complications. 糖尿病、体重指数、肝脂肪变性和肝切除术风险之间的相互作用:胰岛素依赖型糖尿病是主要并发症的最大风险。

HPB surgery : a world journal of hepatic, pancreatic and biliary surgery Pub Date : 2014-01-01 Epub Date: 2014-08-14 DOI: 10.1155/2014/586159

M G Wiggans, J T Lordan, G Shahtahmassebi, S Aroori, M J Bowles, D A Stell

{"title":"The Interaction between Diabetes, Body Mass Index, Hepatic Steatosis, and Risk of Liver Resection: Insulin Dependent Diabetes Is the Greatest Risk for Major Complications.","authors":"M G Wiggans, J T Lordan, G Shahtahmassebi, S Aroori, M J Bowles, D A Stell","doi":"10.1155/2014/586159","DOIUrl":"https://doi.org/10.1155/2014/586159","url":null,"abstract":"Background. This study aimed to assess the relationship between diabetes, obesity, and hepatic steatosis in patients undergoing liver resection and to determine if these factors are independent predictors of major complications. Materials and Methods. Analysis of a prospectively maintained database of patients undergoing liver resection between 2005 and 2012 was undertaken. Background liver was assessed for steatosis and classified as <33% and ≥33%. Major complications were defined as Grade III-V complications using the Dindo-Clavien classification. Results. 504 patients underwent liver resection, of whom 56 had diabetes and 61 had steatosis ≥33%. Median BMI was 26 kg/m(2) (16-54 kg/m(2)). 94 patients developed a major complication (18.7%). BMI ≥ 25 kg/m(2) (P = 0.001) and diabetes (P = 0.018) were associated with steatosis ≥33%. Only insulin dependent diabetes was a risk factor for major complications (P = 0.028). Age, male gender, hypoalbuminaemia, synchronous bowel procedures, extent of resection, and blood transfusion were also independent risk factors. Conclusions. Liver surgery in the presence of steatosis, elevated BMI, and non-insulin dependent diabetes is not associated with major complications. Although diabetes requiring insulin therapy was a significant risk factor, the major risk factors relate to technical aspects of surgery, particularly synchronous bowel procedures. ","PeriodicalId":77165,"journal":{"name":"HPB surgery : a world journal of hepatic, pancreatic and biliary surgery","volume":"2014 ","pages":"586159"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/586159","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32651296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Laparoscopic versus Open Liver Resection: Differences in Intraoperative and Early Postoperative Outcome among Cirrhotic Patients with Hepatocellular Carcinoma-A Retrospective Observational Study. 腹腔镜与开放式肝切除术:肝硬化肝细胞癌患者术中及术后早期预后的差异——回顾性观察研究

HPB surgery : a world journal of hepatic, pancreatic and biliary surgery Pub Date : 2014-01-01 Epub Date: 2014-12-04 DOI: 10.1155/2014/871251

Antonio Siniscalchi, Giorgio Ercolani, Giulia Tarozzi, Lorenzo Gamberini, Lucia Cipolat, Antonio D Pinna, Stefano Faenza

{"title":"Laparoscopic versus Open Liver Resection: Differences in Intraoperative and Early Postoperative Outcome among Cirrhotic Patients with Hepatocellular Carcinoma-A Retrospective Observational Study.","authors":"Antonio Siniscalchi, Giorgio Ercolani, Giulia Tarozzi, Lorenzo Gamberini, Lucia Cipolat, Antonio D Pinna, Stefano Faenza","doi":"10.1155/2014/871251","DOIUrl":"https://doi.org/10.1155/2014/871251","url":null,"abstract":"Introduction. Laparoscopic liver resection is considered risky in cirrhotic patients, even if minor surgical trauma of laparoscopy could be useful to prevent deterioration of a compromised liver function. This study aimed to identify the differences in terms of perioperative complications and early outcome in cirrhotic patients undergoing minor hepatic resection for hepatocellular carcinoma with open or laparoscopic technique. Methods. In this retrospective study, 156 cirrhotic patients undergoing liver resection for hepatocellular carcinoma were divided into two groups according to type of surgical approach: laparoscopy (LS group: 23 patients) or laparotomy (LT group: 133 patients). Perioperative data, mortality, and length of hospital stay were recorded. Results. Groups were matched for type of resection, median number of nodules, and median diameter of largest lesions. Groups were also homogeneous for preoperative liver and renal function tests. Intraoperative haemoglobin decrease and transfusions of red blood cells and fresh frozen plasma were significantly lower in LS group. MELD score lasted stable after laparoscopic resection, while it increased in laparotomic group. Postoperative liver and renal failure and mortality were all lower in LS group. Conclusions. Lower morbidity and mortality, maintenance of liver function, and shorter hospital stay suggest the safety and benefit of laparoscopic approach. ","PeriodicalId":77165,"journal":{"name":"HPB surgery : a world journal of hepatic, pancreatic and biliary surgery","volume":"2014 ","pages":"871251"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/871251","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32942290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 22

The Association between Survival and the Pathologic Features of Periampullary Tumors Varies over Time. 壶腹周围肿瘤的生存与病理特征之间的关系随着时间的推移而变化。

HPB surgery : a world journal of hepatic, pancreatic and biliary surgery Pub Date : 2014-01-01 Epub Date: 2014-07-01 DOI: 10.1155/2014/890530

Jennifer K Plichta, Anjali S Godambe, Zachary Fridirici, Sherri Yong, James M Sinacore, Gerard J Abood, Gerard V Aranha

{"title":"The Association between Survival and the Pathologic Features of Periampullary Tumors Varies over Time.","authors":"Jennifer K Plichta, Anjali S Godambe, Zachary Fridirici, Sherri Yong, James M Sinacore, Gerard J Abood, Gerard V Aranha","doi":"10.1155/2014/890530","DOIUrl":"https://doi.org/10.1155/2014/890530","url":null,"abstract":"Introduction. Several histopathologic features of periampullary tumors have been shown to be correlated with prognosis. We evaluated their association with mortality at multiple time points. Methods. A retrospective chart review identified 207 patients with periampullary adenocarcinomas who underwent pancreaticoduodenectomy between January 1, 2001 and December 31, 2009. Clinicopathologic features were assessed, and the data were analyzed using univariate and multivariate methods. Results. In univariate analysis, perineural invasion had a strong association with 1-year mortality (OR 3.03, CI 1.42-6.47), and one lymph node (LN) increase in the LN ratio (LNR) equated with a 5-fold increase in mortality. In contrast, LN status (OR 6.42, CI 3.32-12.41) and perineural invasion (OR 5.44, CI 2.81-10.52) had the strongest associations with mortality at 3 years. Using Cox proportional hazards, perineural invasion (HR 2.61, CI 1.77-3.85) and LN status (HR 2.69, CI 1.84-3.95) had robust associations with overall mortality. Recursive partitioning analysis identified LNR as the most important risk factor for mortality at 1 and 3 years. Conclusions. Overall mortality was closely related to the LNR within the first year, while longer follow-up periods demonstrated a stronger association with perineural invasion and overall LN status. Therefore, the current staging for periampullary tumors may need to be updated to include the LNR. ","PeriodicalId":77165,"journal":{"name":"HPB surgery : a world journal of hepatic, pancreatic and biliary surgery","volume":"2014 ","pages":"890530"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/890530","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32570492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Primary leiomyoma of the liver: a review of a rare tumour. 原发性肝脏平滑肌瘤:一个罕见肿瘤的回顾。

HPB surgery : a world journal of hepatic, pancreatic and biliary surgery Pub Date : 2014-01-01 Epub Date: 2014-11-19 DOI: 10.1155/2014/959202

Ayodeji Oluwarotimi Omiyale

{"title":"Primary leiomyoma of the liver: a review of a rare tumour.","authors":"Ayodeji Oluwarotimi Omiyale","doi":"10.1155/2014/959202","DOIUrl":"https://doi.org/10.1155/2014/959202","url":null,"abstract":"Context. Primary leiomyoma of the liver is a rare tumour with uncertain pathogenesis with similar presentation with other tumours of the liver. Little is known about its clinical course. Objectives. To review the literature for case reports of primary leiomyoma of the liver. Methods. Extensive literature search was carried out for case reports of primary leiomyoma of the liver. Results. A total of 36 cases of primary leiomyoma of the liver were reviewed. The mean age of presentation is 43 years with slight female sex affectation; females accounted for 55.6% of the cases reported in the literature. The average size of the tumour is 8.7 cm. 34.4% of the cases reviewed were incidental finding with the mean follow-up time of 33 months with most cases reporting no evidence of disease. Conclusions. Primary leiomyoma of the liver is very rare tumour with complex pathogenesis which remains largely unknown. Imaging of the tumour does not allow for a tissue specific diagnosis; hence histological review of the tissue specimen and immunohistochemical stains are imperative for diagnosis. Surgical resection is both diagnostic and curative. The diagnosis of primary leiomyoma of the liver should be considered as a differential in the management of liver tumours. ","PeriodicalId":77165,"journal":{"name":"HPB surgery : a world journal of hepatic, pancreatic and biliary surgery","volume":"2014 ","pages":"959202"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/959202","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32906108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 16