HPB surgery : a world journal of hepatic, pancreatic and biliary surgery最新文献_第10页

"Incidentaloma" of the liver: management of a diagnostic and therapeutic dilemma. 肝脏“偶发瘤”:诊断和治疗困境的处理。

HPB surgery : a world journal of hepatic, pancreatic and biliary surgery Pub Date : 2012-01-01 Epub Date: 2012-08-08 DOI: 10.1155/2012/891787

Denis Ehrl, Katharina Rothaug, Peter Herzog, Bernhard Hofer, Horst-Günter Rau

{"title":"\"Incidentaloma\" of the liver: management of a diagnostic and therapeutic dilemma.","authors":"Denis Ehrl, Katharina Rothaug, Peter Herzog, Bernhard Hofer, Horst-Günter Rau","doi":"10.1155/2012/891787","DOIUrl":"https://doi.org/10.1155/2012/891787","url":null,"abstract":"The continuous development of highly sensitive clinical imaging increased the detection of focal lesions of the liver. These accidentally detected liver tumors without liver-specific symptoms such as cholestasis have been named \"incidentalomas.\" Diagnostic tools such as sonography, computed tomography, or magnetic resonance imaging are used increasingly in asymptomatic individuals without defined suspected diagnoses in the setting of general prevention or followup after a history of malignancy. But despite continuous improvement of diagnostics, some doubt regarding the benign or malign behavior of a tumor remains. In case an asymptomatic hemangioma or FNH can be preoperatively detected with certainty, the indication for surgery must be very strict. In case of symptomatic liver lesions surgical resection should only be indicated with tumor-specific symptoms. In the remaining cases of benign lesions of the liver, a \"watch and wait\" strategy is recommended. In case of uncertain diagnosis, especially in patients with positive history of a malignant tumor or the suspected diagnosis of hepatocellular adenoma, surgical resection is indicated. Due to the continuous improvement of surgical techniques, liver resection should be done in the laparoscopic technique. Laparoscopic surgery has lower morbidity and shorter hospitalization than open technique.","PeriodicalId":77165,"journal":{"name":"HPB surgery : a world journal of hepatic, pancreatic and biliary surgery","volume":"2012 ","pages":"891787"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2012/891787","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30864341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 30

Initial experience in single-incision transumbilical laparoscopic liver resection: indications, potential benefits, and limitations. 单切口经脐腹腔镜肝切除术的初步经验:指征、潜在益处和局限性。

HPB surgery : a world journal of hepatic, pancreatic and biliary surgery Pub Date : 2012-01-01 Epub Date: 2012-09-25 DOI: 10.1155/2012/921973

Giovanni Dapri, Livia Dimarco, Guy-Bernard Cadière, Vincent Donckier

{"title":"Initial experience in single-incision transumbilical laparoscopic liver resection: indications, potential benefits, and limitations.","authors":"Giovanni Dapri, Livia Dimarco, Guy-Bernard Cadière, Vincent Donckier","doi":"10.1155/2012/921973","DOIUrl":"https://doi.org/10.1155/2012/921973","url":null,"abstract":"Background. Single-incision transumbilical laparoscopic liver resection (SITLLR) has been recently described in limited series. We report our experience in SITLLR and discuss the future of this approach in terms of indications, potential benefits, and limitations, with a special reference to laparoscopic liver resection (LLR). Patients and Methods. Six patients underwent SITLLR. Indications were biliary cysts (3 cases), hydatid cysts (2), and colorectal liver metastasis (1). Procedures consisted in cysts unroofing, left lateral lobectomy, pericystectomy, and wedge resection. SITLLR was performed with 11 mm reusable trocar, 10 or 5 mm 30° scopes, 10 mm ultrasound probe, curved reusable instruments, and straight disposable bipolar shears. Results. Neither conversion to open surgery nor insertion of supplementary trocars was necessary. Median laparoscopic time was 105.5 minutes and median blood loss 275 mL. Median final umbilical scar length was 1.5 cm, and median length of stay was 4 days. No early or late complications occurred. Conclusion. SITLLR remains a challenging procedure. It is feasible in highly selected patients, requiring experience in hepatobiliary and laparoscopic surgery and skills in single-incision laparoscopy. Apart from cosmetic benefit, our experience and literature review did not show significant advantages if compared with multiport LLR, underlying that specific indications remain to be established.","PeriodicalId":77165,"journal":{"name":"HPB surgery : a world journal of hepatic, pancreatic and biliary surgery","volume":"2012 ","pages":"921973"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2012/921973","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30988675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 19

Bile duct leaks from the intrahepatic biliary tree: a review of its etiology, incidence, and management. 胆管从肝内胆道树渗漏:其病因，发病率和管理的回顾。

HPB surgery : a world journal of hepatic, pancreatic and biliary surgery Pub Date : 2012-01-01 Epub Date: 2012-05-08 DOI: 10.1155/2012/752932

Sorabh Kapoor, Samiran Nundy

引用次数: 37

Klatskin-like lesions. 克拉皮样病变。

HPB surgery : a world journal of hepatic, pancreatic and biliary surgery Pub Date : 2012-01-01 Epub Date: 2012-06-28 DOI: 10.1155/2012/107519

M P Senthil Kumar, R Marudanayagam

引用次数: 0

Laparoscopic management for carcinoid metastasis to the spleen. 脾类癌转移的腹腔镜治疗。

HPB surgery : a world journal of hepatic, pancreatic and biliary surgery Pub Date : 2011-01-01 Epub Date: 2011-04-06 DOI: 10.1155/2011/346507

Damian Balmforth, Christos Skouras, Fausto Palazzo, Emmanouil Zacharakis

引用次数: 9

A novel classification system to address financial impact and referral decisions for bile duct injury in laparoscopic cholecystectomy. 一个新的分类系统，以解决经济影响和转诊决策的胆管损伤在腹腔镜胆囊切除术。

HPB surgery : a world journal of hepatic, pancreatic and biliary surgery Pub Date : 2011-01-01 Epub Date: 2011-09-08 DOI: 10.1155/2011/371245

Robert M Cannon, Guy Brock, Joseph F Buell

引用次数: 24

Disturbances in the glutathione/ophthalmate redox buffer system in the woodchuck model of hepatitis virus-induced hepatocellular carcinoma. 土拨鼠肝炎病毒诱导的肝细胞癌模型中谷胱甘肽/眼酸盐氧化还原缓冲系统的紊乱

HPB surgery : a world journal of hepatic, pancreatic and biliary surgery Pub Date : 2011-01-01 Epub Date: 2011-09-18 DOI: 10.1155/2011/789323

Rafael Andres Ibarra, R Abbas, R S Kombu, Guo-Fang Zhang, G Jacobs, Z Lee, H Brunengraber, J R Sanabria

{"title":"Disturbances in the glutathione/ophthalmate redox buffer system in the woodchuck model of hepatitis virus-induced hepatocellular carcinoma.","authors":"Rafael Andres Ibarra, R Abbas, R S Kombu, Guo-Fang Zhang, G Jacobs, Z Lee, H Brunengraber, J R Sanabria","doi":"10.1155/2011/789323","DOIUrl":"https://doi.org/10.1155/2011/789323","url":null,"abstract":"Purpose. The incidence of liver tumors is rising in USA. The purpose of this study was to evaluate liver oxido-reductive status in the presence of chronic liver disease and hepatocellular carcinoma (HCC). Methods. Glutathione species and ophthalmate (OA) concentrations were measured by LC-MS in processed plasma and red blood cells (RBC) from infected Woodchuck with hepatitis virus (WHV). Blood samples were obtained from: (i) infected animals with tumors (WHV+/HCC+), (ii) infected animals without tumors (WHV+/HCC-) and (iii) healthy animals (WHC-/HCC-). Results. The concentration of reduced glutathione (GSH) and the ratio GSH/GSG were lower in plasma from WHV+/HCC+ animals when compared to WHV+/HCC- and WHV-/HCC- (P < 0.01). In contrast, the concentration of oxidized glutathione (GSSG) was found to be higher in plasma from WHV+/HCC+ animals when compared to WHV+/HCC- and WHV-/HCC- (P < 0.01). The Glutathione species and its ratio from the RBC compartment were similar among all groups. OA concentration in both plasma and RBC was significantly higher from WHV+/HCC+ when compared to WHV+/HCC- and WHV-/HCC- (P < 0.01). Conclusions. Disturbances of the glutathione redox buffer system and higher concentrations of OA were found in the WCV+/HCC+ animal model. The role of these compounds as biomarkers of early tumor development in patients with end stage liver disease remains to be determined.","PeriodicalId":77165,"journal":{"name":"HPB surgery : a world journal of hepatic, pancreatic and biliary surgery","volume":"2011 ","pages":"789323"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2011/789323","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30161359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

A Malignant Gastrointestinal Stromal Tumor of the Gallbladder Immunoreactive for PDGFRA and Negative for CD 117 Antigen (c-KIT). 恶性胃肠道间质瘤PDGFRA免疫反应，cd117抗原(c-KIT)阴性。

HPB surgery : a world journal of hepatic, pancreatic and biliary surgery Pub Date : 2011-01-01 Epub Date: 2011-04-14 DOI: 10.1155/2011/327192

Athanasios Petrou, Pari Alexandrou, Alexandros Papalambros, Angelica Saetta, Paraskevi Fragkou, Michalis Kontos, Nicholas Brennan, Antonio Manzelli, Kostantinos Bramis, Evangelos Felekouras

引用次数: 12

Clinical application of the hanover classification for iatrogenic bile duct lesions. 汉诺威分类在医源性胆管病变中的临床应用。

HPB surgery : a world journal of hepatic, pancreatic and biliary surgery Pub Date : 2011-01-01 Epub Date: 2012-01-05 DOI: 10.1155/2011/612384

Hüseyin Bektas, Moritz Kleine, Azad Tamac, Jürgen Klempnauer, Harald Schrem

{"title":"Clinical application of the hanover classification for iatrogenic bile duct lesions.","authors":"Hüseyin Bektas, Moritz Kleine, Azad Tamac, Jürgen Klempnauer, Harald Schrem","doi":"10.1155/2011/612384","DOIUrl":"https://doi.org/10.1155/2011/612384","url":null,"abstract":"Background. There is only limited evidence available to justify generalized clinical classification and treatment recommendations for iatrogenic bile duct lesions. Methods. Data of 93 patients with iatrogenic bile duct lesions was evaluated retrospectively to analyse the variety of encountered lesions with the Hanover classification and its impact on surgical treatment and outcomes. Results. Bile duct lesions combined with vascular lesions were observed in 20 patients (21.5%). 18 of these patients were treated with additional partial hepatectomy while the majority were treated by hepaticojejunostomy alone (n = 54). Concomitant injury to the right hepatic artery resulted in additional right anatomical hemihepatectomy in 10 of 18 cases. 8 of 12 cases with type A lesions were treated with drainage alone or direct suture of the bile leak while 2 patients with a C2 lesion required a Whipple's procedure. Observed congruence between originally proposed lesion-type-specific treatment and actually performed treatment was 66-100% dependent on the category of lesion type. Hospital mortality was 3.2% (n = 3). Conclusions. The Hannover classification may be helpful to standardize the systematic description of iatrogenic bile duct lesions in order to establish evidence-based and lesion-type-specific treatment recommendations.","PeriodicalId":77165,"journal":{"name":"HPB surgery : a world journal of hepatic, pancreatic and biliary surgery","volume":"2011 ","pages":"612384"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2011/612384","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30408359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 23

The dynamics of glutathione species and ophthalmate concentrations in plasma from the VX2 rabbit model of secondary liver tumors. VX2兔继发性肝肿瘤模型血浆中谷胱甘肽种类和眼药浓度的变化。

HPB surgery : a world journal of hepatic, pancreatic and biliary surgery Pub Date : 2011-01-01 Epub Date: 2011-02-17 DOI: 10.1155/2011/709052

R Abbas, R S Kombu, R A Ibarra, K K Goyal, H Brunengraber, J R Sanabria

{"title":"The dynamics of glutathione species and ophthalmate concentrations in plasma from the VX2 rabbit model of secondary liver tumors.","authors":"R Abbas, R S Kombu, R A Ibarra, K K Goyal, H Brunengraber, J R Sanabria","doi":"10.1155/2011/709052","DOIUrl":"https://doi.org/10.1155/2011/709052","url":null,"abstract":"Purpose: Available tumor markers have low sensitivity/specificity for the diagnosis of liver tumors. The present study was designed to evaluate the oxidoreductive status of the liver as surrogates of tumor subsistence and growth.Methods: Glutathione species (GSH:GSSG), ophthalmate (OA) concentrations, and their turnover were measured in plasma of rabbits (n = 6) in their healthy state and in the state of tumor growth after implantation of the VX2 carcinoma in their liver. Tumors were allowed to grow for a period of 14 days when rabbits were sacrificed. Livers were removed and cysteine concentration was measured in liver tissue.Results: Tumor growth was found in 100% of the rabbits. Concentration and labeling of GSH/GSSG were similar in experimental animals before and after tumor implantation and to sham animals. In contrast, OA concentration increased significantly in experimental animals after tumor implantation when compared to same animals prior to tumor implantation and to sham animals (P < .05). The concentration of cysteine, a precursor of GSH, was found to be significantly lower in the liver tissue adjacent to the tumor (P < .05).Conclusion: Disturbances in the oxidoreductive state of livers appear to be a surrogate of early tumor growth.","PeriodicalId":77165,"journal":{"name":"HPB surgery : a world journal of hepatic, pancreatic and biliary surgery","volume":"2011 ","pages":"709052"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2011/709052","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29697468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 16