Karen-Beth G Scholthof, T Erik Mirkov, Herman B Scholthof
{"title":"Plant virus gene vectors: biotechnology applications in agriculture and medicine.","authors":"Karen-Beth G Scholthof, T Erik Mirkov, Herman B Scholthof","doi":"10.1007/978-1-4615-0721-5_4","DOIUrl":"https://doi.org/10.1007/978-1-4615-0721-5_4","url":null,"abstract":"","PeriodicalId":77144,"journal":{"name":"Genetic engineering","volume":"24 ","pages":"67-85"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/978-1-4615-0721-5_4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22096341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The use of DNA polymorphisms in genetic mapping.","authors":"Christopher A Cullis","doi":"10.1007/978-1-4615-0721-5_8","DOIUrl":"https://doi.org/10.1007/978-1-4615-0721-5_8","url":null,"abstract":"<p><p>The introduction of molecular markers has revolutionized genetics. The range of polymorphisms that are available is increasing and the advent of large-scale cDNA and genomic sequencing is a source of an ever-increasing set of available markers. The ease with which any particular marker type can be applied to an experimental system depends, to some extent, on the amount of genomic information available for that system. However, comparative genomics is enabling a wider range of marker technology to be applied to relatively information-poor systems. The types of markers that are available include restriction fragment length polymorphisms, amplified fragment length polymorphisms, ransom amplified polymorphic DNAs, simple sequence repeats, single nucleotide polymorphisms and small insertions/deletions. The types of questions that can be addressed with these molecular markers include the generation of genetic and physical maps for the identification of interesting loci, the development of marker-based gene tags, map-based cloning of agronomically important genes, synteny mapping, marker-assisted selection and quantitative trait analysis. The continued development of technology including new high throughput methods, for example those being applied to single nucleotide polymorphisms, will change the ease with which current questions can be answered as well as enable new analyses that are presently impossible to undertake.</p>","PeriodicalId":77144,"journal":{"name":"Genetic engineering","volume":"24 ","pages":"179-89"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/978-1-4615-0721-5_8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22096345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Protein quality control in bacterial cells: integrated networks of chaperones and ATP-dependent proteases.","authors":"John M Flanagan, Maria C Bewley","doi":"10.1007/978-1-4615-0721-5_2","DOIUrl":"https://doi.org/10.1007/978-1-4615-0721-5_2","url":null,"abstract":"","PeriodicalId":77144,"journal":{"name":"Genetic engineering","volume":"24 ","pages":"17-47"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22096339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Integrins and the myocardium.","authors":"S. Shai, A. Harpf, R. Ross","doi":"10.1161/HH1101.091862","DOIUrl":"https://doi.org/10.1161/HH1101.091862","url":null,"abstract":"Abstract—Extracellular matrix provides a structural, chemical, and mechanical substrate that is essential in cardiac development, growth, and responses to pathophysiological signals. Transmembrane receptors termed integrins provide a dynamic interaction of environmental cues and intracellular events. Integrins orchestrate multiple functions in the intact organism including organogenesis, regulation of gene expression, cell proliferation, differentiation, migration, and death. They are expressed in all cellular components of the cardiovascular system, including the vasculature, blood, cardiac myocytes and nonmuscle cardiac cells. The focus of this review will be on the role of integrins in the myocardium. We will provide background on integrin structure and function, discuss how the expression of integrins is critical to the form and function of the developing and postnatal myocardium, and review the known data on integrins as signaling molecules in the heart. Finally, we will offer insights to the future ...","PeriodicalId":77144,"journal":{"name":"Genetic engineering","volume":"24 1","pages":"87-105"},"PeriodicalIF":0.0,"publicationDate":"2001-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1161/HH1101.091862","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64429734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evolution of transport proteins.","authors":"Milton H. Saier","doi":"10.1007/0-306-47572-3_1","DOIUrl":"https://doi.org/10.1007/0-306-47572-3_1","url":null,"abstract":"","PeriodicalId":77144,"journal":{"name":"Genetic engineering","volume":"23 1","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"2001-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/0-306-47572-3_1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51344328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mechanisms of apoptosis repression.","authors":"C. Vu, J. Cidlowski","doi":"10.1007/0-306-47572-3_2","DOIUrl":"https://doi.org/10.1007/0-306-47572-3_2","url":null,"abstract":"","PeriodicalId":77144,"journal":{"name":"Genetic engineering","volume":"23 1","pages":"11-33"},"PeriodicalIF":0.0,"publicationDate":"2001-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51344361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Deconstructing a conserved protein family: the role of MCM proteins in eukaryotic DNA replication.","authors":"S. Pasion, S. Forsburg","doi":"10.1007/0-306-47572-3_8","DOIUrl":"https://doi.org/10.1007/0-306-47572-3_8","url":null,"abstract":"","PeriodicalId":77144,"journal":{"name":"Genetic engineering","volume":"23 1","pages":"129-55"},"PeriodicalIF":0.0,"publicationDate":"2001-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/0-306-47572-3_8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51344421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cytokine activation of transcription.","authors":"K. Mowen, M. David","doi":"10.1007/0-306-47572-3_3","DOIUrl":"https://doi.org/10.1007/0-306-47572-3_3","url":null,"abstract":"","PeriodicalId":77144,"journal":{"name":"Genetic engineering","volume":"23 1","pages":"35-44"},"PeriodicalIF":0.0,"publicationDate":"2001-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/0-306-47572-3_3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51344373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}