Genetic engineering最新文献

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An introduction to 13C metabolic flux analysis. 介绍13C代谢通量分析。
Genetic engineering Pub Date : 2002-01-01 DOI: 10.1007/978-1-4615-0721-5_10
Wolfgang Wiechert
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引用次数: 37
Gene silencing--principles and application. 基因沉默——原理与应用。
Genetic engineering Pub Date : 2002-01-01 DOI: 10.1007/978-1-4615-0721-5_11
Cathryn Horser, David Abbott, Varsha Wesley, Neil Smith, Peter Waterhouse
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引用次数: 5
Plant virus gene vectors: biotechnology applications in agriculture and medicine. 植物病毒基因载体:生物技术在农业和医学中的应用。
Genetic engineering Pub Date : 2002-01-01 DOI: 10.1007/978-1-4615-0721-5_4
Karen-Beth G Scholthof, T Erik Mirkov, Herman B Scholthof
{"title":"Plant virus gene vectors: biotechnology applications in agriculture and medicine.","authors":"Karen-Beth G Scholthof, T Erik Mirkov, Herman B Scholthof","doi":"10.1007/978-1-4615-0721-5_4","DOIUrl":"https://doi.org/10.1007/978-1-4615-0721-5_4","url":null,"abstract":"","PeriodicalId":77144,"journal":{"name":"Genetic engineering","volume":"24 ","pages":"67-85"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/978-1-4615-0721-5_4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22096341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 31
The use of DNA polymorphisms in genetic mapping. DNA多态性在遗传作图中的应用。
Genetic engineering Pub Date : 2002-01-01 DOI: 10.1007/978-1-4615-0721-5_8
Christopher A Cullis
{"title":"The use of DNA polymorphisms in genetic mapping.","authors":"Christopher A Cullis","doi":"10.1007/978-1-4615-0721-5_8","DOIUrl":"https://doi.org/10.1007/978-1-4615-0721-5_8","url":null,"abstract":"<p><p>The introduction of molecular markers has revolutionized genetics. The range of polymorphisms that are available is increasing and the advent of large-scale cDNA and genomic sequencing is a source of an ever-increasing set of available markers. The ease with which any particular marker type can be applied to an experimental system depends, to some extent, on the amount of genomic information available for that system. However, comparative genomics is enabling a wider range of marker technology to be applied to relatively information-poor systems. The types of markers that are available include restriction fragment length polymorphisms, amplified fragment length polymorphisms, ransom amplified polymorphic DNAs, simple sequence repeats, single nucleotide polymorphisms and small insertions/deletions. The types of questions that can be addressed with these molecular markers include the generation of genetic and physical maps for the identification of interesting loci, the development of marker-based gene tags, map-based cloning of agronomically important genes, synteny mapping, marker-assisted selection and quantitative trait analysis. The continued development of technology including new high throughput methods, for example those being applied to single nucleotide polymorphisms, will change the ease with which current questions can be answered as well as enable new analyses that are presently impossible to undertake.</p>","PeriodicalId":77144,"journal":{"name":"Genetic engineering","volume":"24 ","pages":"179-89"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/978-1-4615-0721-5_8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22096345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 23
Protein quality control in bacterial cells: integrated networks of chaperones and ATP-dependent proteases. 细菌细胞中的蛋白质质量控制:伴侣蛋白和atp依赖性蛋白酶的整合网络。
Genetic engineering Pub Date : 2002-01-01 DOI: 10.1007/978-1-4615-0721-5_2
John M Flanagan, Maria C Bewley
{"title":"Protein quality control in bacterial cells: integrated networks of chaperones and ATP-dependent proteases.","authors":"John M Flanagan,&nbsp;Maria C Bewley","doi":"10.1007/978-1-4615-0721-5_2","DOIUrl":"https://doi.org/10.1007/978-1-4615-0721-5_2","url":null,"abstract":"","PeriodicalId":77144,"journal":{"name":"Genetic engineering","volume":"24 ","pages":"17-47"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22096339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Integrins and the myocardium. 整合素和心肌。
Genetic engineering Pub Date : 2001-06-08 DOI: 10.1161/HH1101.091862
S. Shai, A. Harpf, R. Ross
{"title":"Integrins and the myocardium.","authors":"S. Shai, A. Harpf, R. Ross","doi":"10.1161/HH1101.091862","DOIUrl":"https://doi.org/10.1161/HH1101.091862","url":null,"abstract":"Abstract—Extracellular matrix provides a structural, chemical, and mechanical substrate that is essential in cardiac development, growth, and responses to pathophysiological signals. Transmembrane receptors termed integrins provide a dynamic interaction of environmental cues and intracellular events. Integrins orchestrate multiple functions in the intact organism including organogenesis, regulation of gene expression, cell proliferation, differentiation, migration, and death. They are expressed in all cellular components of the cardiovascular system, including the vasculature, blood, cardiac myocytes and nonmuscle cardiac cells. The focus of this review will be on the role of integrins in the myocardium. We will provide background on integrin structure and function, discuss how the expression of integrins is critical to the form and function of the developing and postnatal myocardium, and review the known data on integrins as signaling molecules in the heart. Finally, we will offer insights to the future ...","PeriodicalId":77144,"journal":{"name":"Genetic engineering","volume":"24 1","pages":"87-105"},"PeriodicalIF":0.0,"publicationDate":"2001-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1161/HH1101.091862","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64429734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 421
Evolution of transport proteins. 转运蛋白的进化。
Genetic engineering Pub Date : 2001-01-01 DOI: 10.1007/0-306-47572-3_1
Milton H. Saier
{"title":"Evolution of transport proteins.","authors":"Milton H. Saier","doi":"10.1007/0-306-47572-3_1","DOIUrl":"https://doi.org/10.1007/0-306-47572-3_1","url":null,"abstract":"","PeriodicalId":77144,"journal":{"name":"Genetic engineering","volume":"23 1","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"2001-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/0-306-47572-3_1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51344328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 27
Mechanisms of apoptosis repression. 细胞凋亡抑制机制。
Genetic engineering Pub Date : 2001-01-01 DOI: 10.1007/0-306-47572-3_2
C. Vu, J. Cidlowski
{"title":"Mechanisms of apoptosis repression.","authors":"C. Vu, J. Cidlowski","doi":"10.1007/0-306-47572-3_2","DOIUrl":"https://doi.org/10.1007/0-306-47572-3_2","url":null,"abstract":"","PeriodicalId":77144,"journal":{"name":"Genetic engineering","volume":"23 1","pages":"11-33"},"PeriodicalIF":0.0,"publicationDate":"2001-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51344361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Deconstructing a conserved protein family: the role of MCM proteins in eukaryotic DNA replication. 解构保守蛋白家族:MCM蛋白在真核生物DNA复制中的作用。
Genetic engineering Pub Date : 2001-01-01 DOI: 10.1007/0-306-47572-3_8
S. Pasion, S. Forsburg
{"title":"Deconstructing a conserved protein family: the role of MCM proteins in eukaryotic DNA replication.","authors":"S. Pasion, S. Forsburg","doi":"10.1007/0-306-47572-3_8","DOIUrl":"https://doi.org/10.1007/0-306-47572-3_8","url":null,"abstract":"","PeriodicalId":77144,"journal":{"name":"Genetic engineering","volume":"23 1","pages":"129-55"},"PeriodicalIF":0.0,"publicationDate":"2001-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/0-306-47572-3_8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51344421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Cytokine activation of transcription. 细胞因子的转录激活。
Genetic engineering Pub Date : 2001-01-01 DOI: 10.1007/0-306-47572-3_3
K. Mowen, M. David
{"title":"Cytokine activation of transcription.","authors":"K. Mowen, M. David","doi":"10.1007/0-306-47572-3_3","DOIUrl":"https://doi.org/10.1007/0-306-47572-3_3","url":null,"abstract":"","PeriodicalId":77144,"journal":{"name":"Genetic engineering","volume":"23 1","pages":"35-44"},"PeriodicalIF":0.0,"publicationDate":"2001-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/0-306-47572-3_3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51344373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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