{"title":"[The components of the negative chronotropic effect of the vagus nerve on the heart and a method for their definition].","authors":"Iu R Sheĭkh-Zade, I L Cherednik","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Stimulation of the peripheral end of the right n.vagus led to synchronizing of the vagal and cardiac rhythms in anesthetised cats. The stimulation of the n.vagus beyond the synchronizing range resulted in the sinus arrhythmia. The negative chronotropic effect of the vagus nerve on the heart was shown to consist of tonic as well as synchronizing components. The latter component did not depend on the heart rate and may be expressed as a difference between the maximal and minimal cardiac cycle during the sinus arrhythmia. The tonic component was determined as a difference between the initial cardiac cycle and the minimal cardiac cycle during the sinus arrhythmia. It seems to be cumulative in nature and to depend on the heart rate.</p>","PeriodicalId":77130,"journal":{"name":"Fiziologicheskii zhurnal imeni I.M. Sechenova","volume":"82 10-11","pages":"58-63"},"PeriodicalIF":0.0,"publicationDate":"1996-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20109481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V A Shul'ga, N N Barykina, T A Alekhina, V G Kolpakov
{"title":"[The physiological characteristics of genetic predisposition to catalepsy in rats depending on the stage of selection].","authors":"V A Shul'ga, N N Barykina, T A Alekhina, V G Kolpakov","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Male rats with a genetic predisposition to cataleptic reactions revealed a reduced motor activity and a diminished activation of mineralocorticoid and testosterone synthesis in response to a mild stress as compared with the Wistar rats. The reactions, however, were exactly opposite in the Wistar rats with signs of cataleptic features. The data obtained suggest that, when creating genetic animal models of human diseases, the initial stages of breeding should correspond to early stages of the disease whereas advanced stages of breeding are similar to later, chronic phases of the disease.</p>","PeriodicalId":77130,"journal":{"name":"Fiziologicheskii zhurnal imeni I.M. Sechenova","volume":"82 10-11","pages":"77-83"},"PeriodicalIF":0.0,"publicationDate":"1996-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20109937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The biochemical changes in the blood of variously adapted persons under exposure to different physical loads who develop tolerance].","authors":"K Milasius","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Study of the energy metabolism indices and those of acid-alkaline balance in highly trained sportsmen and in the beginners revealed a dependence of the organism biochemical changes on intensity of physical loads, thus indicating a direct relationship between the energy metabolism rate and the degree of the athletes organism's adaptation. The study revealed fluctuations of regenerative processes during 24 hours and specified the contribution of each energy source to energy production under a variety of physical load. A growing adaptation of the athlete organism to physical loads results in a stronger correlation ties among separate indices of the energy metabolism.</p>","PeriodicalId":77130,"journal":{"name":"Fiziologicheskii zhurnal imeni I.M. Sechenova","volume":"82 10-11","pages":"98-107"},"PeriodicalIF":0.0,"publicationDate":"1996-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20110029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S V Ul'kin, V F Piatin, A N Volobuev, V G Shakhov, O G Lagno
{"title":"[An automated system for determining tracheobronchial resistance].","authors":"S V Ul'kin, V F Piatin, A N Volobuev, V G Shakhov, O G Lagno","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77130,"journal":{"name":"Fiziologicheskii zhurnal imeni I.M. Sechenova","volume":"82 10-11","pages":"126-30"},"PeriodicalIF":0.0,"publicationDate":"1996-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20109474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The dynamics of the somatotropin content in the follicular fluid during maturation and atresia of the antral follicles in bovine ovaries].","authors":"I Iu Lebedeva, T I Kuz'mina, V A Lebedev","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Somatotropin level was shown to rise in follicular fluid from bovine ovaries during the follicular growth stage with increasing of the follicular diameter from 3-5 to 6-10 mm. Follicles with the diameter of 10-20 mm containing over 40% of pycnotic granulosa cells revealed lower levels of somatotropin in their fluid as compared with those containing 20% or lesser amount of pycnotic cells. The data obtained suggest a direct involvement of somatotropin in regulation of the growth and atretic processes in antral bovine ovarian follicles.</p>","PeriodicalId":77130,"journal":{"name":"Fiziologicheskii zhurnal imeni I.M. Sechenova","volume":"82 10-11","pages":"91-7"},"PeriodicalIF":0.0,"publicationDate":"1996-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20110026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A A Shandra, L S Godlevskiĭ, R S Vast'ianov, M B Zaporozhchenko, M Ibragim, A I Brusentsov, A A Oleĭnik
{"title":"[A rotational syndrome induced by administration of the delta sleep-inducing peptide into the reticular portion of the rat substantia nigra].","authors":"A A Shandra, L S Godlevskiĭ, R S Vast'ianov, M B Zaporozhchenko, M Ibragim, A I Brusentsov, A A Oleĭnik","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Unilateral intranigral administration of a delta-sleep-induced peptide (DSIP) evoked a contralateral rotation. Naloxon prevented development of the effect whereas haloperidol administration enhanced the DSIP cataleptogenic effect.</p>","PeriodicalId":77130,"journal":{"name":"Fiziologicheskii zhurnal imeni I.M. Sechenova","volume":"82 10-11","pages":"69-72"},"PeriodicalIF":0.0,"publicationDate":"1996-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20110027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T M Vinogradova, T N Iuzniuk, A V Zaĭtsev, L V Rozenshtraukh
{"title":"[The development of local nonexcitability in sinus node cells and other cells with diastolic depolarization in the right atrium of the rabbit under the action of acetylcholine].","authors":"T M Vinogradova, T N Iuzniuk, A V Zaĭtsev, L V Rozenshtraukh","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The sinus node is heterogeneous structure. In the intact sinus node acetylcholine induced shift of pacemaker from the center of sinus node suggesting higher sensitivity of typical pacemaker cells to acetylcholine. The aim of this study was to compare the acetylcholine (10(-5), 10(-4) M) action on different cell types in the intercaval region as well as in the sinus node. The rabbit right atrium, with the sinus node region intact, was pinned in a tissue bath. One or two microelectrodes were impaled in the sinus node and atrial electrogram was obtained simultaneously. During superfusion with acetylcholine though the preparations retained regular rhythm some of the cells with diastolic depolarization became inexcitable, their amplitude fell below 30% of the control value while others did not. In pacemaker cells (upstroke velocity < 5 V/s; smooth transition from diastolic depolarization into upstroke) occurrence of inexcitability was the highest: 36 of 40 cells (90%). With increasing upstroke velocity, the occurrence of inexcitability decreased. Effects of acetylcholine were completely reversible and were blocked by pretreatment with atropine 10(-7) M. It may be suggested that particular sensitivity of typical pacemaker cells to acetylcholine could arise from two facts: 1. In typical pacemaker cells calcium current plays the main role in action potential upstroke; 2. The calcium current in the sinus node cells is particular sensitive to acetylcholine.</p>","PeriodicalId":77130,"journal":{"name":"Fiziologicheskii zhurnal imeni I.M. Sechenova","volume":"82 10-11","pages":"1-19"},"PeriodicalIF":0.0,"publicationDate":"1996-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20109471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V P Krotov, V Convertino, V I Korol'kov, R Latham, E V Trambovetskiĭ, J Fanton, R Crisman, A N Truzhennikov, D Evert, A M Nosovskiĭ, J Conolly
{"title":"[Heart functions in monkeys during a 2-week antiorthostatic hypokinesia].","authors":"V P Krotov, V Convertino, V I Korol'kov, R Latham, E V Trambovetskiĭ, J Fanton, R Crisman, A N Truzhennikov, D Evert, A M Nosovskiĭ, J Conolly","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Dynamics of the left heart ventricular muscle contractility and compliance was studied in 4 monkeys in the head down position (antiorthostatic hypokinesia) with the body angle 10 during 2 weeks. Functional tests on a tilt table and under two conditions of centrifuge rotation were performed prior to and after the antiorthostatic hypokinesia. No changes in the left heart ventricular muscle contractility was found. However, the sensitivity level of the baroreflex control decreased. Compliance of the left heart myocardial fibre increased in the first hours and days of the antiorthostatic hypokinesia.</p>","PeriodicalId":77130,"journal":{"name":"Fiziologicheskii zhurnal imeni I.M. Sechenova","volume":"82 10-11","pages":"34-45"},"PeriodicalIF":0.0,"publicationDate":"1996-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20109478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The functional significance of alpha activity in the visual cortex for the recognition of images and movement].","authors":"I A Shevelev","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The idea of the EEG alpha-waves as a rhythmically spreading scanning process was tested in 27 subjects. The stimuli presentation was not synchronised with the alpha-wave phase in control. In experimental group, recognition of different-shape figures and size coincided with one of four phases of the EEG alpha-wave in occipital area. Under flicker stimulation through closed eyes with the alpha-frequency, 11 of the 12 subjects perceived distinct illusory visual objects. The optimal stimulation frequency was always within the alpha-range and closely correlated with the individual predominant alpha-frequency. The data obtained corroborate the theory that the alpha-wave in the visual cortex reflects a uniformity of the spreading scanning process which plays a major part in the process of visual recognition.</p>","PeriodicalId":77130,"journal":{"name":"Fiziologicheskii zhurnal imeni I.M. Sechenova","volume":"82 10-11","pages":"20-33"},"PeriodicalIF":0.0,"publicationDate":"1996-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20109477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The effect of plaferon on cerebral circulatory hypoxia in rabbits].","authors":"G I Kvrivishvili, N P Mitagvariia","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Local cerebral blood flow (LCBF) was reduced following plaferon administration in rabbits due to impairment of the vasodilator responses of cerebral vessels or their transformation into vasoconstrictor responses, the effect being added to that of vasoconstrictor responses to vasoactive neuropeptides contained in plaferon.</p>","PeriodicalId":77130,"journal":{"name":"Fiziologicheskii zhurnal imeni I.M. Sechenova","volume":"82 10-11","pages":"64-8"},"PeriodicalIF":0.0,"publicationDate":"1996-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20109482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}