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European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics最新文献

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Nomenclature for factors of the HLA System, update September 2000. HLA系统因子命名法，2000年9月更新。
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics Pub Date : 2000-12-01 DOI: 10.1034/j.1399-0039.2000.560615.x
S. Marsh
{"title":"Nomenclature for factors of the HLA System, update September 2000.","authors":"S. Marsh","doi":"10.1034/j.1399-0039.2000.560615.x","DOIUrl":"https://doi.org/10.1034/j.1399-0039.2000.560615.x","url":null,"abstract":"","PeriodicalId":77121,"journal":{"name":"European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84788577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Nomenclature for factors of the HLA System, update October 2000. HLA系统因子命名法，2000年10月更新。
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics Pub Date : 2000-12-01 DOI: 10.1016/S0198-8859(00)00237-8
S. Marsh
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引用次数: 4
Molecular cloning of the cDNAs encoding the feline B-lymphocyte activation antigen B7-1 (CD80) and B7-2 (CD86) homologues which interact with human CTLA4-Ig. 猫b淋巴细胞活化抗原B7-1 (CD80)和B7-2 (CD86)与人CTLA4-Ig相互作用同源基因的克隆
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics Pub Date : 2000-10-01 DOI: 10.1046/j.1365-2370.2000.00221.x
Y Nishimura, M Shimojima, T Miyazawa, E Sato, K Nakamura, Y Izumiya, Y Ikeda, T Mikami, E Takahashi
{"title":"Molecular cloning of the cDNAs encoding the feline B-lymphocyte activation antigen B7-1 (CD80) and B7-2 (CD86) homologues which interact with human CTLA4-Ig.","authors":"Y Nishimura,&nbsp;M Shimojima,&nbsp;T Miyazawa,&nbsp;E Sato,&nbsp;K Nakamura,&nbsp;Y Izumiya,&nbsp;Y Ikeda,&nbsp;T Mikami,&nbsp;E Takahashi","doi":"10.1046/j.1365-2370.2000.00221.x","DOIUrl":"https://doi.org/10.1046/j.1365-2370.2000.00221.x","url":null,"abstract":"<p><p>We cloned the cDNAs encoding the feline homologues of B-lymphocyte activation antigens B7-1 (CD80) and B7-2 (CD86). We expressed recombinant feline CD80 and CD86 molecules by the baculovirus expression system, and demonstrated their binding ability to human CTLA4-murine immunoglobulin fusion protein.</p>","PeriodicalId":77121,"journal":{"name":"European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2000-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1046/j.1365-2370.2000.00221.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21860566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Mouse cytokine gene nucleotide sequence alignments, 2000. Part I. 小鼠细胞因子基因核苷酸序列比对，2000。我一部分。
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics Pub Date : 2000-08-01 DOI: 10.1046/j.1365-2370.2000.00217.x
G J Laundy, J L Bidwell
{"title":"Mouse cytokine gene nucleotide sequence alignments, 2000. Part I.","authors":"G J Laundy,&nbsp;J L Bidwell","doi":"10.1046/j.1365-2370.2000.00217.x","DOIUrl":"https://doi.org/10.1046/j.1365-2370.2000.00217.x","url":null,"abstract":"","PeriodicalId":77121,"journal":{"name":"European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2000-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1046/j.1365-2370.2000.00217.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21830874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
A novel PCR-RFLP assay for the detection of the single nucleotide polymorphism at position -1082 in the human IL-10 gene promoter. 一种新的PCR-RFLP检测人类IL-10基因启动子-1082位单核苷酸多态性的方法。
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics Pub Date : 2000-06-01 DOI: 10.1046/j.1365-2370.2000.00213.x
M R Bazrafshani, W E Ollier, A H Hajeer
{"title":"A novel PCR-RFLP assay for the detection of the single nucleotide polymorphism at position -1082 in the human IL-10 gene promoter.","authors":"M R Bazrafshani,&nbsp;W E Ollier,&nbsp;A H Hajeer","doi":"10.1046/j.1365-2370.2000.00213.x","DOIUrl":"https://doi.org/10.1046/j.1365-2370.2000.00213.x","url":null,"abstract":"","PeriodicalId":77121,"journal":{"name":"European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2000-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21778728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 15
Human immunoglobulin VH4 sequences resolved by population-based analysis after enzymatic amplification and denaturing gradient gel electrophoresis. 人免疫球蛋白VH4序列经酶扩增和变性梯度凝胶电泳后进行群体分析。
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics Pub Date : 2000-02-01 DOI: 10.1046/j.1365-2370.2000.00191.x
X Cui, H Li
{"title":"Human immunoglobulin VH4 sequences resolved by population-based analysis after enzymatic amplification and denaturing gradient gel electrophoresis.","authors":"X Cui,&nbsp;H Li","doi":"10.1046/j.1365-2370.2000.00191.x","DOIUrl":"https://doi.org/10.1046/j.1365-2370.2000.00191.x","url":null,"abstract":"<p><p>Exhaustive gene identification followed by assignment of the genes identified to corresponding loci is a key step in elucidating the physical structure of a multigene family. However, problems occur in this process because genes in a multigene family usually share a high degree of sequence identity and are highly polymorphic. To address these problems, an efficient population-based approach was developed. Using this approach, sequences in the human immunoglobulin VH4 family were amplified by PCR with family-specific primers. Denaturing gradient gel electrophoresis (DGGE) was used to separate the resulting sequences with either very similar or identical sizes and differing by as little as 1 base pair (bp). Eighteen distinct bands and 21 banding patterns were observed in the samples collected from 41 unrelated individuals. Of the 18 bands, 12 were polymorphic. No sample had all 18 bands. The estimated frequencies for the alleles represented by the 18 bands ranged from 1.2 to 100%. The 18 sequences differed from each other by 1-19 bases (0.7 to 13%) within the 145-146-bp amplified region. Sequences in eight bands (44%) were not reported previously. These results were used to assign the majority (14 out of 18) of the VH4 sequences to 10 loci. This PCR-DGGE method, in conjunction with a population-based assay, may also be used to study other multigene families including those involved in the development of the immune system.</p>","PeriodicalId":77121,"journal":{"name":"European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2000-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21506825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Nomenclature for factors of the HLA system, 1998. HLA系统因子命名法，1998。
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics Pub Date : 1999-04-01 DOI: 10.1046/j.1365-2370.1999.00164.x
J G Bodmer, S G Marsh, E D Albert, W F Bodmer, R E Bontrop, B Dupont, H A Erlich, J A Hansen, B Mach, W R Mayr, P Parham, E W Petersdorf, T Sasazuki, G M Schreuder, J L Strominger, A Svejgaard, P I Terasaki
{"title":"Nomenclature for factors of the HLA system, 1998.","authors":"J G Bodmer,&nbsp;S G Marsh,&nbsp;E D Albert,&nbsp;W F Bodmer,&nbsp;R E Bontrop,&nbsp;B Dupont,&nbsp;H A Erlich,&nbsp;J A Hansen,&nbsp;B Mach,&nbsp;W R Mayr,&nbsp;P Parham,&nbsp;E W Petersdorf,&nbsp;T Sasazuki,&nbsp;G M Schreuder,&nbsp;J L Strominger,&nbsp;A Svejgaard,&nbsp;P I Terasaki","doi":"10.1046/j.1365-2370.1999.00164.x","DOIUrl":"https://doi.org/10.1046/j.1365-2370.1999.00164.x","url":null,"abstract":"","PeriodicalId":77121,"journal":{"name":"European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1999-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1046/j.1365-2370.1999.00164.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21200120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 153
Negative association between type 1 diabetes and HLA DQB1*0602-DQA1*0102 is attenuated with age at onset. Swedish Childhood Diabetes Study Group. 1型糖尿病与HLA DQB1*0602-DQA1*0102的负相关随发病年龄的增加而减弱。瑞典儿童糖尿病研究小组。
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics Pub Date : 1999-04-01
J Graham, I Kockum, C B Sanjeevi, M Landin-Olsson, L Nyström, G Sundkvist, H Arnqvist, G Blohmé, F Lithner, B Littorin, B Scherstén, L Wibell, J Ostman, A Lernmark, N Breslow, G Dahlquist
{"title":"Negative association between type 1 diabetes and HLA DQB1*0602-DQA1*0102 is attenuated with age at onset. Swedish Childhood Diabetes Study Group.","authors":"J Graham,&nbsp;I Kockum,&nbsp;C B Sanjeevi,&nbsp;M Landin-Olsson,&nbsp;L Nyström,&nbsp;G Sundkvist,&nbsp;H Arnqvist,&nbsp;G Blohmé,&nbsp;F Lithner,&nbsp;B Littorin,&nbsp;B Scherstén,&nbsp;L Wibell,&nbsp;J Ostman,&nbsp;A Lernmark,&nbsp;N Breslow,&nbsp;G Dahlquist","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>HLA-associated relative risks of type 1 (insulin-dependent) diabetes mellitus were analysed in population-based Swedish patients and controls aged 0-34 years. The age dependence of HLA-associated relative risks was assessed by likelihood ratio tests of regression parameters in separate logistic regression models for each HLA category. The analyses demonstrated an attenuation with increasing age at onset in the relative risk for the positively associated DQB1*0201-A1*0502/B1*0302-A1*0301 (DQ2/8) genotype (P = 0.02) and the negatively associated DQB1*0602-A1*0102 (DQ6.2) haplotype (P = 0.004). At birth, DQ6.2-positive individuals had an estimated relative risk of 0.03, but this increased to 1.1 at age 35 years. Relative risks for individuals with DQ genotype 8/8 or 8/X or DQ genotype 2/2 or 2/X, where X is any DQ haplotype other than 2, 8 or 6.2, were not significantly age-dependent. An exploratory analysis of DQ haplotypes other than 2, 8 and 6.2 suggested that the risk of type 1 diabetes increases with age for DQB1*0604-A1*0102 (DQ6.4) and that the peak risk for the negatively associated DQB1*0301-A1*0501 haplotype is at age 18 years. There was also weak evidence that the risk for DQB1*0303-A1*0301 (DQ9), which has a positive association in the Japanese population, may decrease with age. We speculate that HLA-DQ alleles have a significant effect on the rate of beta cell destruction, which is accelerated in DQ2/8-positive individuals and inhibited, but not completely blocked, in DQ6.2-positive individuals.</p>","PeriodicalId":77121,"journal":{"name":"European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1999-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21200121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nomenclature for factors of the HLA system, update September 1998. HLA系统因子命名法，1998年9月更新。
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics Pub Date : 1998-12-01
S G Marsh
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引用次数: 0
Nomenclature for factors of the HLA system, update August 1998. HLA系统因子命名法，1998年8月更新。
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics Pub Date : 1998-12-01
S G Marsh
{"title":"Nomenclature for factors of the HLA system, update August 1998.","authors":"S G Marsh","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77121,"journal":{"name":"European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1998-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20855027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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