Clinical reviews in allergy最新文献_第9页

The potential use of monoclonal antibodies as therapeutic modalities in neonatal infection. 单克隆抗体作为新生儿感染治疗方式的潜在应用。

Clinical reviews in allergy Pub Date : 1992-02-01 DOI: 10.1007/978-1-4612-0417-6_3

H R Hill, L A Gonzales, D K Kelsey, H V Raff

引用次数: 0

Clinical use of immune serum globulin as replacement therapy in patients with primary immunodeficiency syndromes. 免疫血清球蛋白作为原发性免疫缺陷综合征患者替代疗法的临床应用。

Clinical reviews in allergy Pub Date : 1992-02-01 DOI: 10.1007/978-1-4612-0417-6_1

S A Schwartz

引用次数: 12

The use of IVIG in neurological disease. 免疫球蛋白在神经系统疾病中的应用。

Clinical reviews in allergy Pub Date : 1992-02-01 DOI: 10.1007/978-1-4612-0417-6_10

A I Levinson

引用次数: 7

Asthma. A role for IVIG therapy? 哮喘。免疫球蛋白治疗的作用?

Clinical reviews in allergy Pub Date : 1992-02-01

P Fireman, G Friday

{"title":"Asthma. A role for IVIG therapy?","authors":"P Fireman, G Friday","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Asthma is a multifactorial, reversible, obstructive lung disease that manifests airway inflammation as well as airway hyperreactivity. In addition to IgE-mediated respiratory reactions, the pathophysiology of asthma can be triggered by both viral respiratory and bacterial sinopulmonary infections. Even though most asthma patients do not manifest undue susceptibility to infection, a subset of asthma patients with recurrent sinopulmonary as well as upper-respiratory infections may have an associated immune deficiency syndrome. In a subset of these patients, deficiencies of serum IgG subclasses have also been described in the presence of low-normal or normal serum IgG and also deficient serum IgA. In addition to the usual asthma therapy with beta 2 agonist and theophylline bronchodilators as well as cromolyn and steroids, many of these immunodeficiency patients will benefit from iv gamma-globulin therapy. However, we suggest that an inability to synthesize specific serum antibody to injected vaccines or immunogens be a prerequisite before initiating iv gamma-globulin therapy. The clinician should not rely on serum IgG subclass levels alone as a criterion for initiation of passive immune globulin therapy. There may be another cohort of asthma patients who could benefit from iv gamma-globulin therapy. In a small open-label pilot study severe steroid-dependent asthma patients who were not immunodeficient and did not have undue susceptibility to infection were treated with iv gamma-globulin with a very large dosage protocol of 2000 mg/kg monthly.(ABSTRACT TRUNCATED AT 250 WORDS)</p>","PeriodicalId":77073,"journal":{"name":"Clinical reviews in allergy","volume":"10 1-2","pages":"135-42"},"PeriodicalIF":0.0,"publicationDate":"1992-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12772758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Immune deficiencies in chronic lymphocytic leukemia and multiple myeloma. 慢性淋巴细胞白血病和多发性骨髓瘤的免疫缺陷。

Clinical reviews in allergy Pub Date : 1992-02-01 DOI: 10.1007/978-1-4612-0417-6_4

A Winkelstein, P S Jordan

引用次数: 13

IVIG in the treatment of children with acute and chronic idiopathic thrombocytopenic purpura and the autoimmune cytopenias. IVIG治疗儿童急慢性特发性血小板减少性紫癜及自身免疫性细胞减少症

Clinical reviews in allergy Pub Date : 1992-02-01 DOI: 10.1007/978-1-4612-0417-6_5

D J Nugent

引用次数: 5

Current status of intravenous immunoglobulin in preventing or treating neonatal bacterial infections. 静脉注射免疫球蛋白预防或治疗新生儿细菌感染的现状。

Clinical reviews in allergy Pub Date : 1992-02-01 DOI: 10.1007/978-1-4612-0417-6_2

L E Weisman, D F Cruess, G W Fischer