Bailliere's clinical obstetrics and gynaecology最新文献_第2页

2 Neuraxial opioids in labour 2 .分娩过程中轴向阿片类药物

Bailliere's clinical obstetrics and gynaecology Pub Date : 1998-09-01 DOI: 10.1016/S0950-3552(98)80072-2

MBBS Deborah J. Wilson (Clinical Research Fellow) , MD, FRCPC M. Joanne Douglas (Clinical Professor, Head)

引用次数: 4

8 New amide local anaesthetics for obstetric use 产科用新型酰胺局麻药

Bailliere's clinical obstetrics and gynaecology Pub Date : 1998-09-01 DOI: 10.1016/S0950-3552(98)80078-3

MD Esther M. Yun (Assistant Professor of Anethesiology), MD Warner Meadows (Instructor in Anesthesiology), MD Alan C. Santos (Associate Professor of Anesthesiology, Obstetrics and Gynecology)

{"title":"8 New amide local anaesthetics for obstetric use","authors":"MD Esther M. Yun (Assistant Professor of Anethesiology), MD Warner Meadows (Instructor in Anesthesiology), MD Alan C. Santos (Associate Professor of Anesthesiology, Obstetrics and Gynecology)","doi":"10.1016/S0950-3552(98)80078-3","DOIUrl":"https://doi.org/10.1016/S0950-3552(98)80078-3","url":null,"abstract":"<div><p>For a number of reasons, bupivacaine has become the most frequently used local anaesthetic in obstetric anaesthesia, despite the fact that it has a narrower margin of safety than other local anesthetics. In recent years, advances in technology have made singleisomer formulations of drugs available for clinical use. Generally speaking, the levo stereoisomer of amide local anaesthetic has a lowe rpotential for systemic toxicity than the dextro form of the drug while retaining anaesthetic potency. Ropivacaine (Naropin<sup>®</sup>, Astra Ltd), a homologue of mepivacaine and bupivacaine, has recently been released for use. Its clinical efficacy appears to be quite similar to that of bupivacaine but it has a greater margin of safety. The other drug currently being investigated is levobupivacaine (Chirocaine<sup>®</sup>, Chiroscience Ltd). Both drugs appear to be similar in efficacy to the currently used formulation of bupivacaine; however, they are more costly. Thus, cost-benefit analyses are required to define more clearly their future role in obstetric anaesthesia.</p></div>","PeriodicalId":77031,"journal":{"name":"Bailliere's clinical obstetrics and gynaecology","volume":"12 3","pages":"Pages 461-471"},"PeriodicalIF":0.0,"publicationDate":"1998-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0950-3552(98)80078-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92006562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

3 New epidural techniques for labour analgesia: patient-controlled epidural analgesia and combined spinal-epidural analgesia 新硬膜外分娩镇痛技术:患者自控硬膜外镇痛和脊髓-硬膜外联合镇痛

Bailliere's clinical obstetrics and gynaecology Pub Date : 1998-09-01 DOI: 10.1016/S0950-3552(98)80073-4

MBBS, DRCOG, FRCA, FANZCA Michael Paech (Staff Anaesthetist)

引用次数: 10

9 The effects of epidural analgesia on the course and outcome of labour 硬膜外镇痛对分娩过程和结局的影响

Bailliere's clinical obstetrics and gynaecology Pub Date : 1998-09-01 DOI: 10.1016/S0950-3552(98)80079-5

MD Mieczyslaw Finster (Professor of Anesthesiology, Obstetrics and Gynecology), MD Alan C. Santos (Associate Professor of Anesthesiology, Obstetrics and Gynecology)

{"title":"9 The effects of epidural analgesia on the course and outcome of labour","authors":"MD Mieczyslaw Finster (Professor of Anesthesiology, Obstetrics and Gynecology), MD Alan C. Santos (Associate Professor of Anesthesiology, Obstetrics and Gynecology)","doi":"10.1016/S0950-3552(98)80079-5","DOIUrl":"https://doi.org/10.1016/S0950-3552(98)80079-5","url":null,"abstract":"<div><p>The potential effects of epidural analgesia on the progress and outcome of labour have been the subject of lasting controversy. Retrospective reviews indicate that epidurals are associated with longer labours and/or an increase in the incidence of instrumental or operative delivery. Similar results were obtained in non-randomized prospective studies. None of them established a causal relationship, because without randomization the selection bias cannot be ruled out. Other factors, such as premature rupture of membranes and maternal socioeconomic status, may affect the outcome of labour. It was also reported that introduction of the on-demand epidural service did not increase the primary caesarean section rate. The few prospective randomized studies are contradictory and not very reliable owing to small patient populations and high cross-over rates. There is, however, unanimity among the authors regarding the superiority of pain relief provided by epidural blocks over systemically administered opioids.</p></div>","PeriodicalId":77031,"journal":{"name":"Bailliere's clinical obstetrics and gynaecology","volume":"12 3","pages":"Pages 473-483"},"PeriodicalIF":0.0,"publicationDate":"1998-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0950-3552(98)80079-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92006559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

7 The substance-abusing parturient: implications for analgesia and anaesthesia management 药物滥用产妇:镇痛和麻醉管理的意义

Bailliere's clinical obstetrics and gynaecology Pub Date : 1998-09-01 DOI: 10.1016/S0950-3552(98)80077-1

MD David J. Birnbach (Director of Obstetric Anesthesiology, Associate Professor of Anesthesiology in Obstetrics and Gynecology) , MD Deborah J. Stein (Associate Director of Obstetric Anesthesiology, Assistant Professor of Anesthesiology)

引用次数: 8

Index 指数

Bailliere's clinical obstetrics and gynaecology Pub Date : 1998-09-01 DOI: 10.1016/S0950-3552(98)80082-5

引用次数: 0

10 The long-term effects of analgesia in labour 分娩镇痛的长期影响

Bailliere's clinical obstetrics and gynaecology Pub Date : 1998-09-01 DOI: 10.1016/S0950-3552(98)80080-1

MB, BS, FRCA Jacqueline Durbridge (Specialist Registrar in Anaesthesia), MD, FRCA Anita Holdcroft (Reader in Anaesthesia)

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引用次数: 8

4 Promising non-narcotic analgesic techniques for labour 4、有前景的非麻醉性分娩镇痛技术

Bailliere's clinical obstetrics and gynaecology Pub Date : 1998-09-01 DOI: 10.1016/S0950-3552(98)80074-6

MD Frédéric J. Mercier (Assistant Professor of Anaesthesia, Head of the Unit of Obstetric Anaesthesia), MD Dan Benhamou (Professor of Anaesthesia, Chairman of the Department of Anaesthesia)

{"title":"4 Promising non-narcotic analgesic techniques for labour","authors":"MD Frédéric J. Mercier (Assistant Professor of Anaesthesia, Head of the Unit of Obstetric Anaesthesia), MD Dan Benhamou (Professor of Anaesthesia, Chairman of the Department of Anaesthesia)","doi":"10.1016/S0950-3552(98)80074-6","DOIUrl":"https://doi.org/10.1016/S0950-3552(98)80074-6","url":null,"abstract":"<div><p>Epidural analgesia and spinal analgesia are the most effective techniques for relieving labour pain. Basically, local anaesthetics (i.e. bupivacaine) and opioids (i.e. fentanyl or sufentanil), especially when combined, produce excellent analgesia with minimal motor blockade. However, none of these agents is devoid of side-effects and analgesia remains sometimes imperfect, suggesting that new drugs would be welcome. Adrenalin and clonidine act on a<sub>2</sub>-adrenoceptors in the spinal cord and both have been found to improve analgesia. These two drugs have already been used in many patients and studies because the absence of neurotoxicity has been well documented. Clonidine looks more attractive, although sedation and hypotension limit its use. Other analgesic drugs are promising alternatives but are still at an experimental or very early clinical stage. Neostigmine and ketamine (without preservative) are not neurotoxic while midazolam neurotoxicity is still controversial. Intravenous remifentanil might prove useful when neuraxial analgesia is contraindicated.</p></div>","PeriodicalId":77031,"journal":{"name":"Bailliere's clinical obstetrics and gynaecology","volume":"12 3","pages":"Pages 397-407"},"PeriodicalIF":0.0,"publicationDate":"1998-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0950-3552(98)80074-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92088442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

11 Maternal satisfaction with labour analgesia 11产妇对分娩镇痛的满意度

Bailliere's clinical obstetrics and gynaecology Pub Date : 1998-09-01 DOI: 10.1016/S0950-3552(98)80081-3

MBBS, FFARACS, Dip. Health Med. Law Andrew Ross (Deputy Director)

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引用次数: 25

1 Physiology of pain in labour 分娩疼痛的生理学

Bailliere's clinical obstetrics and gynaecology Pub Date : 1998-09-01 DOI: 10.1016/S0950-3552(98)80071-0

MBBS, FRACOG Shelley Rowlands (Fellow in Perinatal Medicine), MD, MRCP, MRCOG, FRACOG Michael Permezel (Professor)

引用次数: 45