{"title":"Adenylyl cyclases and alcohol.","authors":"B Tabakoff, P L Hoffman","doi":"10.1016/s1040-7952(98)80011-6","DOIUrl":"https://doi.org/10.1016/s1040-7952(98)80011-6","url":null,"abstract":"","PeriodicalId":76981,"journal":{"name":"Advances in second messenger and phosphoprotein research","volume":"32 ","pages":"173-93"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20350064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Regulation of cAMP signaling by phosphorylation.","authors":"Y Ishikawa","doi":"10.1016/s1040-7952(98)80007-4","DOIUrl":"https://doi.org/10.1016/s1040-7952(98)80007-4","url":null,"abstract":"","PeriodicalId":76981,"journal":{"name":"Advances in second messenger and phosphoprotein research","volume":"32 ","pages":"99-120"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20350060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Simultaneous fluorescence ratio imaging of cyclic AMP and calcium kinetics in single living cells.","authors":"M A DeBernardi, G Brooker","doi":"10.1016/s1040-7952(98)80012-8","DOIUrl":"https://doi.org/10.1016/s1040-7952(98)80012-8","url":null,"abstract":"","PeriodicalId":76981,"journal":{"name":"Advances in second messenger and phosphoprotein research","volume":"32 ","pages":"195-213"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20350065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F A Antoni, S M Smith, J Simpson, R Rosie, G Fink, J M Paterson
{"title":"Calcium control of adenylyl cyclase: the calcineurin connection.","authors":"F A Antoni, S M Smith, J Simpson, R Rosie, G Fink, J M Paterson","doi":"10.1016/s1040-7952(98)80010-4","DOIUrl":"https://doi.org/10.1016/s1040-7952(98)80010-4","url":null,"abstract":"","PeriodicalId":76981,"journal":{"name":"Advances in second messenger and phosphoprotein research","volume":"32 ","pages":"153-72"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20350063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Modulation of sodium and calcium channels by protein phosphorylation and G proteins.","authors":"W A Catterall","doi":"10.1016/s1040-7952(97)80017-1","DOIUrl":"https://doi.org/10.1016/s1040-7952(97)80017-1","url":null,"abstract":"","PeriodicalId":76981,"journal":{"name":"Advances in second messenger and phosphoprotein research","volume":"31 ","pages":"159-81"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20276682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K Taskén, B S Skålhegg, K A Taskén, R Solberg, H K Knutsen, F O Levy, M Sandberg, S Orstavik, T Larsen, A K Johansen, T Vang, H P Schrader, N T Reinton, K M Torgersen, V Hansson, T Jahnsen
{"title":"Structure, function, and regulation of human cAMP-dependent protein kinases.","authors":"K Taskén, B S Skålhegg, K A Taskén, R Solberg, H K Knutsen, F O Levy, M Sandberg, S Orstavik, T Larsen, A K Johansen, T Vang, H P Schrader, N T Reinton, K M Torgersen, V Hansson, T Jahnsen","doi":"10.1016/s1040-7952(97)80019-5","DOIUrl":"https://doi.org/10.1016/s1040-7952(97)80019-5","url":null,"abstract":"<p><p>A large number of hormones, neurotransmitters, and other signaling substances that bind to G-protein-coupled cell-surface receptors have their signals converge at one sole second messenger, cAMP. The question of how specificity can be maintained in a signal-transduction system in which many extracellular signals leading to a vast array of intracellular responses are all mediated through one second-messenger system has been the subject of thorough investigation and a great deal of speculation. An increasing number of cAK isozymes, consisting of homo- or heterodimers of R subunits (RIalpha, RIbeta, RIIalpha, RIIbeta) with associated catalytic subunits (C alpha, Cbeta, Cgamma), may, at least in part, explain this specificity. The various cAK isozymes display distinct biochemical properties, and the heterogeneous subunits of cAK reveal cell-specific expression and differential regulation at the level of gene transcription, mRNA stability, and protein stability in response to a wide range of hormones and other signaling substances. The existence of a number of anchoring proteins specific to either RIIalpha or RIIbeta, and which localize cAKII isozymes toward distinct substrates at defined subcellular loci, strongly supports the idea that specific functions can be assigned to the various cAK isozymes. The demonstration that selective activation of cAKI is necessary and sufficient for cAMP-mediated inhibition of T-cell proliferation, and the observation that T-cell activation is associated with redistribution and colocalization of cAKI to the TCR, is also compatible with the notion of isozyme-specific effects.</p>","PeriodicalId":76981,"journal":{"name":"Advances in second messenger and phosphoprotein research","volume":"31 ","pages":"191-204"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20276684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L N Johnson, D Barford, D J Owen, M E Noble, E F Garman
{"title":"From phosphorylase to phosphorylase kinase.","authors":"L N Johnson, D Barford, D J Owen, M E Noble, E F Garman","doi":"10.1016/s1040-7952(97)80005-5","DOIUrl":"https://doi.org/10.1016/s1040-7952(97)80005-5","url":null,"abstract":"","PeriodicalId":76981,"journal":{"name":"Advances in second messenger and phosphoprotein research","volume":"31 ","pages":"11-28"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20275568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R B Reed, M Sandberg, T Jahnsen, S M Lohmann, S H Francis, J D Corbin
{"title":"Structural order of the slow and fast intrasubunit cGMP-binding sites of type I alpha cGMP-dependent protein kinase.","authors":"R B Reed, M Sandberg, T Jahnsen, S M Lohmann, S H Francis, J D Corbin","doi":"10.1016/s1040-7952(97)80020-1","DOIUrl":"https://doi.org/10.1016/s1040-7952(97)80020-1","url":null,"abstract":"","PeriodicalId":76981,"journal":{"name":"Advances in second messenger and phosphoprotein research","volume":"31 ","pages":"205-17"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20276685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rab3A-rabphilin-3A system in neurotransmitter release.","authors":"T Sasaki, H Shirataki, H Nakanishi, Y Takai","doi":"10.1016/s1040-7952(97)80025-0","DOIUrl":"10.1016/s1040-7952(97)80025-0","url":null,"abstract":"","PeriodicalId":76981,"journal":{"name":"Advances in second messenger and phosphoprotein research","volume":"31 ","pages":"279-94"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20276690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N Uyttersprot, A Allgeier, M Baptist, D Christophe, F Coppee, K Coulonval, S Deleu, F Depoortere, S Dremier, F Lamy, C Ledent, C Maenhaut, F Miot, V Panneels, J Parma, M Parmentier, I Pirson, V Pohl, P Roger, V Savonet, M Taton, M Tonacchera, J van Sande, F Wilkin, G Vassart
{"title":"The cAMP in thyroid: from the TSH receptor to mitogenesis and tumorigenesis.","authors":"N Uyttersprot, A Allgeier, M Baptist, D Christophe, F Coppee, K Coulonval, S Deleu, F Depoortere, S Dremier, F Lamy, C Ledent, C Maenhaut, F Miot, V Panneels, J Parma, M Parmentier, I Pirson, V Pohl, P Roger, V Savonet, M Taton, M Tonacchera, J van Sande, F Wilkin, G Vassart","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76981,"journal":{"name":"Advances in second messenger and phosphoprotein research","volume":"31 ","pages":"125-40"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20276679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}