发布求助
文献互助 智能选刊 最新文献

Advances in dermatology最新文献

筛选
英文 中文
Advances in prognostication of cutaneous malignant melanoma. 皮肤恶性黑色素瘤预后研究进展。
Advances in dermatology Pub Date : 2004-01-01
Sunita Penmatcha, Sherry A Rovinsky, Clay J Cockerell, Mei-Yu Hsu
{"title":"Advances in prognostication of cutaneous malignant melanoma.","authors":"Sunita Penmatcha, Sherry A Rovinsky, Clay J Cockerell, Mei-Yu Hsu","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76978,"journal":{"name":"Advances in dermatology","volume":"20 ","pages":"323-43"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24814150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vascular endothelial cell adhesion and signaling during leukocyte recruitment. 白细胞募集过程中血管内皮细胞的粘附和信号传导。
Advances in dermatology Pub Date : 2004-01-01
Martin S Kluger
{"title":"Vascular endothelial cell adhesion and signaling during leukocyte recruitment.","authors":"Martin S Kluger","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>During inflammation, coordinated expression of cytokine-induced adhesion molecules (CAMs) on postcapillary venular endothelial cells (ECs) regulates leukocyte recruitment. During their recruitment from blood, leukocytes adhere to EC CAMs, activating signaling pathways inside ECs. In a forthcoming paradigm, leukocyte transendothelial migration requires active EC participation, with extracellular adhesive CAM functions mirrored by cytoplasmic do-main-dependent intracellular events. These events serve to reorganize the EC actin cytoskeleton. Investigators have visualized this as changes in EC shape, transient opening of EC-EC contacts, and redistribution of CAMs expressed on the luminal EC surface. In this review, we (1) summarize the overlapping extracellular adhesive properties of the 3 EC CAMs most important for leukocyte recruitment during inflammation, namely, E-selectin, vascular cell adhesion molecule, and intercellular adhesion molecule-1; (2) explore the role of these 3 CAMs as signal transducers by identifying the intracellular signals (Ca++, Rho/Rac, and phosphatidylinositol 4,5-bisphosphate) that upon leukocyte engagement, reorganize the EC cytoskeleton and redistribute these apical CAMs, thereby favoring leukocyte recruitment; and (3) describe how CAM-derived signals lead to ezrin-radixin-moesin complex formation and how this complex of plasma membrane-cytoskeleton adapter proteins coordinates CAM-driven intracellular signals with extracellular adhesive CAM functions. This literature review suggests that the cytoplasmic domains of these EC CAMs and their downstream effectors represent new and potentially beneficial intracellular therapeutic targets for treating diseases of the skin.</p>","PeriodicalId":76978,"journal":{"name":"Advances in dermatology","volume":"20 ","pages":"163-201"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24814143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cutaneous biology of gammadelta T cells. γ - T细胞的皮肤生物学。
Advances in dermatology Pub Date : 2004-01-01
Michael Girardi
{"title":"Cutaneous biology of gammadelta T cells.","authors":"Michael Girardi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The vast majority of serious noninfectious skin diseases are the result of inappropriate inflammatory responses (eg, atopic dermatitis, psoriasis) or neoplastic transformation (eg, squamous cell carcinoma, melanoma, cutaneous T-cell lymphoma). T cells are critical to both of these major disease categories, playing critical roles in driving or controlling inflammation, as well as the immunosurveillance of cutaneous tumors. T cells may express either 1 of 2 major T-cell receptor (TCR) subtypes composed of heterodimeric alphabeta or gammadelta proteins. While most T cells in the blood and lymph nodes are of the alphabeta type and demonstrate vast heterogeneity, gammadelta T cells are relatively enriched in epithelial tissues and often show less TCR variability. This distinction is especially evident in mice and several other mammals, as well as in humans, albeit to a lesser degree. Recent studies in laboratory animals have indicated the capacity of gammadelta T cells to play major roles in maintenance of the epidermal barrier, regulation of cutaneous inflammation, and protection against cutaneous neoplasms. This review will expound on the biology of gammadelta T cells, their relationship to the skin, and the implications for our understanding of cutaneous disease.</p>","PeriodicalId":76978,"journal":{"name":"Advances in dermatology","volume":"20 ","pages":"203-15"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24814145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Innovative treatments for chronic dermatitis. 创新治疗慢性皮炎。
Advances in dermatology Pub Date : 2004-01-01
J Mark Jackson
{"title":"Innovative treatments for chronic dermatitis.","authors":"J Mark Jackson","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76978,"journal":{"name":"Advances in dermatology","volume":"20 ","pages":"293-322"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24814149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pediatric dermatologic surgery: a surgical approach to the cutaneous features of tuberous sclerosis complex. 小儿皮肤外科:结节性硬化症复合体皮肤特征的外科方法。
Advances in dermatology Pub Date : 2004-01-01
Susan M Sweeney
{"title":"Pediatric dermatologic surgery: a surgical approach to the cutaneous features of tuberous sclerosis complex.","authors":"Susan M Sweeney","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76978,"journal":{"name":"Advances in dermatology","volume":"20 ","pages":"117-35"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24814744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In vivo reflectance-mode confocal scanning laser microscopy in dermatology. 皮肤病学中的体内反射模式共聚焦扫描激光显微术。
Advances in dermatology Pub Date : 2004-01-01
Salvador González, Yolanda Gilaberte-Calzada, Antonia González-Rodríguez, Abel Torres, Martin C Mihm
{"title":"In vivo reflectance-mode confocal scanning laser microscopy in dermatology.","authors":"Salvador González,&nbsp;Yolanda Gilaberte-Calzada,&nbsp;Antonia González-Rodríguez,&nbsp;Abel Torres,&nbsp;Martin C Mihm","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>RCM offers tremendous potential for the advancement of medical research and clinical care. In research, it offers benefits both ex vivo and in vivo. Ex vivo, it can allow us to sample tissue and evaluate it noninvasively to determine what further testing--on the same exact tissue--may be helpful. In vivo RCM can be used to study normal or pathophysiologic processes in real-time noninvasively and by the same technique sequentially over time. Immunologic events previously only studied ex vivo or by static images can be traced from their inception to completion (Table 1). The potential of RCM in vivo is tremendous. How would our world change if we could noninvasively diagnose skin lesions and, with the advent of new minimally invasive therapies, administer treatment and noninvasively monitor that treatment? The potential to allow better medical care based on actual visualization of therapeutic response and healing is obvious. Much like early X-ray and ultrasound imaging, RCM is in its infancy. It is only a matter of time and continued persistent research that will lead to similar success and utility for RCM.</p>","PeriodicalId":76978,"journal":{"name":"Advances in dermatology","volume":"20 ","pages":"371-87"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24814641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical repair of the auricle. 耳廓术耳廓的外科修复
Advances in dermatology Pub Date : 2004-01-01
Edward B Desciak, Yehuda D Eliezri
{"title":"Surgical repair of the auricle.","authors":"Edward B Desciak,&nbsp;Yehuda D Eliezri","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Secondary intention, primary closure, and full thickness skin grafts can handle the majority of ear closures. Transposition flaps work nicely at the root of the helix, the preauricular area, the intertragal notch and the postauricular area. Helical rim advancements and their variations are the workhorse for repairing and restoring the natural arch of the helix. Retroauricular 2-stage pedicle flaps with or without a cartilage graft will provide a nice cosmetic result for larger defects involving the helical rim. Remember, most importantly, know your wound, know your patient, and the simplest closure is often the best one.</p>","PeriodicalId":76978,"journal":{"name":"Advances in dermatology","volume":"20 ","pages":"137-61"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24814745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Update in the diagnosis of keratinocytic neoplasia. 角化细胞瘤诊断的最新进展。
Advances in dermatology Pub Date : 2004-01-01
Jennifer Clay Cather, J Christian Cather, Clay J Cockerell
{"title":"Update in the diagnosis of keratinocytic neoplasia.","authors":"Jennifer Clay Cather,&nbsp;J Christian Cather,&nbsp;Clay J Cockerell","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76978,"journal":{"name":"Advances in dermatology","volume":"20 ","pages":"345-69"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24814151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neurofibromatosis-1 in childhood. 儿童神经纤维瘤病-1。
Advances in dermatology Pub Date : 2004-01-01
Robert Listernick, Joel Charrow
{"title":"Neurofibromatosis-1 in childhood.","authors":"Robert Listernick,&nbsp;Joel Charrow","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76978,"journal":{"name":"Advances in dermatology","volume":"20 ","pages":"75-115"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24814743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
What's news in pediatric dermatology: an update. 儿科皮肤病学最新消息:最新进展。
Advances in dermatology Pub Date : 2004-01-01
Albert C Yan, Andrew C Krakowski, Paul J Honig
{"title":"What's news in pediatric dermatology: an update.","authors":"Albert C Yan,&nbsp;Andrew C Krakowski,&nbsp;Paul J Honig","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76978,"journal":{"name":"Advances in dermatology","volume":"20 ","pages":"1-21"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24814740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信
小红书